International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. This most current release in this highly cited series focuses on such timely topics as novel treatments in immunotherapy in breast cancer, chemokine receptor signaling and the hallmarks of cancer, tumor-targeting antibodies, and a section on mitochondrion and whether they are a common organelle for cell death. As always, readers will find the articles in this series to be of great value, with a high impact and average cited half-life of nine years. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This great resource ranks high amongst scientific journals dealing with cell biology.

Manganese (Mn) oxides are among the most reactive minerals in the earth's surface environment, and play a significant role in adsorption, co-precipitation and redox reactions, affecting biogeochemical cycles of numerous nutrients and contaminants. In addition, manganese oxides are widely applied as absorbents, ion sieves, chemical oxidants and catalysts for environmental remediation and pollution control. There are, however, still many aspects poorly understood in terms of the environmental geochemistry of manganese oxides, such as biogenic formation mechanisms, detailed crystal structure of nanocrystalline phases, electron transfer paths in redox reactions, adsorption mechanisms of contaminants on surfaces, physiochemical factors controlling the contents of structural Mn(III) and vacant sites that largely determine Mn oxide reactivity, and the role of Mn(III) in the above processes. This book aims to bring together advances on manganese oxide environmental biogeochemistry from leading scientists in multiple disciplines, e.g., mineralogy, geochemistry, soil science and environmental engineering. A number of frontier research topics are included in the book, such as in-situ characterization of Mn oxide reactivity with As and Cr, kinetics and molecular-scale mechanisms of metal oxidation by mangnese oxides, mechanistic understanding of metal sorption through density function theory, the role of surface edge sites of birnessites in metal(loid) sorption, reactivity of natural crytomelane, pathways of phyllomanganate transformation to todorokite, water-oxidation catalysis by manganese oxides, in situ As immobilization using stabilized Fe-Mn binary oxides, and synthesis of Li ion-sieves from biogenic oxides and stability of colloidal Mn oxides. The book should be of interest to scientists and engineers in a broad range of disciplines, such as geochemistry, soil science, mineralogy, microbiology, materials science, and environment engineering, as well as graduate students who are engaged in research on manganese oxide biogeochemistry and the engineering application of Mn-bearing materials.

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Neurotrophins, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions, and the biological actions of neurotrophins related to clinical conditions and disease. Each volume is thoroughly reviewed and focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others.

Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

A Generalized Framework of Linear Multivariable Control proposes a number of generalized models by using the generalized inverse of matrix, while the usual linear multivariable control theory relies on some regular models. The book supports that in H-infinity control, the linear fractional transformation formulation is relying on the inverse of the block matrix. If the block matrix is not regular, the H-infinity control does not apply any more in the normal framework. Therefore, it is very important to relax those restrictions to generalize the classical notions and models to include some non-regular cases. This book is ideal for scholars, academics, professional engineer and students who are interested in control system theory.

Origins of the Earth, Moon, and Life: An Interdisciplinary Approach presents state-of-the-art knowledge that is based on theories, experiments, observations, calculations, and analytical data from five astro-sciences, astronomy, astrobiology, astrogeology, astrophysics, and cosmochemistry. Beginning with the origin of elements, and moving on to cover the formation of the early Solar System, the giant impact model of the Earth and Moon, the oldest records of life, and the possibility of life on other planets in the Solar System, this interdisciplinary reference provides a complex understanding of the planets and the formation of life. Synthesizing concepts from all branches of astro-sciences into one, the book is a valuable reference for researchers in astrogeology, astrophysics, cosmochemistry, astrobiology, astronomy, and other space science fields, helping users better understand the intersection of these sciences.

The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome. * Covers sections on model systems and functional studies, imaging-based approaches, and emerging studies* Includes chapters written by experts in the field* Contains cutting-edge material on the topics discussed

Networks of Invasion bridges a conceptual gap between ecological network studies and invasion biology studies. This book contains chapters detailing pressing concerns regarding invasive species in food webs, but also extends the idea of networks of invasion to other systems, such as mutualistic networks or even the human microbiome. Chapters describe the tools, models, and empirical methods adapted for tackling invasions in ecological networks.

Molecular Biology of Placental Development and Disease, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease.

Proteomics in Biology Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field, and a focus on proteomics for this updated volume.

This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry.

Single-Molecule Enzymology, Part B, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, and nanopore and tethered particle motion.

Enzymology at the Membrane Interface, the latest volume in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes.

Annual Reports on NMR Spectroscopy provides a thorough and in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications. Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained as much significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required, and where the nature of interactions and reactions in solution is being studied. This book has established itself as a premier means for both specialists and non-specialists looking to familiarize themselves with the newest techniques and applications pertaining to NMR spectroscopy.

J.B.S. Haldane (1892-1964) is widely appreciated as one of the greatest and most influential British scientists of the 20th century, making significant contributions to genetics, physiology, biochemistry, biometry, cosmology, and other sciences. More remarkable, then, is the fact that Haldane had no formal qualification in science. He made frequent appearances in the media, making pronouncements on a variety of poignant topics including mining disasters, meteorites, politics, and the economy, and was a popular scientific essay writer. Haldane also was famed for conducting painful experiments on himself, including several instances in which he permanently himself. A staunch Marxist and convert to Hinduism, Haldane lived a diverse, lively and interesting life that is still revered by today's science community. A biography of Haldane has not been attempted since 1968, and that book provided an incomplete account of the man's scientific achievement. "The Life and Works of J.B.S. Haldane" serves to fix this glaring omission, providing a complete biographical sketch written by Krishna Dronamraju, one of the last living men to have worked personally with Haldane. A new genre of biographies of 20th-century scientists has come into being, and thus far works have been written about men like Einstein, Oppenheimer, Bernal, Galton, and many more; the inclusion of Haldane within this genre is an absolute necessity. Dronamraju evaluates Haldane's social and political background, as well as his scientific creativity and accomplishments. Haldane embodies a generation of intellectuals who believed and promoted knowledge for its own sake, and that spirit of scientific curiosity and passion is captured in this biography.

Advances in Imaging and Electron Physics merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. The series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.

Advances in Catalysis fills the gap between journal papers and textbooks across the diverse areas of catalysis research. For more than 60 years, this series has dedicated itself to record and present the latest progress in the field of catalysis, providing the scientific community with comprehensive and authoritative reviews. This series is an invaluable and comprehensive resource for chemical engineers and chemists working in the field of catalysis in both academia and industry.

Imaging Bacterial Molecules, Structures and Cells, the latest volume in the Methods in Microbiology series, provides comprehensive, cutting-edge reviews of current and emerging technologies in the field of clinical microbiology. The book features a wide variety of state-of-the art methods and techniques for the diagnosis and management of microbial infections, with chapters authored by internationally renowned experts. This particular volume focuses on current techniques, such as MALDI-TOF mass spectroscopy and molecular diagnostics, along with newly emerging technologies, such as host-based diagnostics and next generation sequencing.

Advances in Organometallic Chemistry contains authoritative review articles of worldwide known researchers on the field of organometallic chemistry, covering topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. The book will benefit a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies, and practical applications.

Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science, and physics. The book's main emphasis is on rare earth elements [Sc, Y, and the lanthanides (La through Lu], but whenever relevant, information is also included on the closely related actinide elements. Individual chapters are comprehensive, broad, up-to-date, critical reviews written by highly experienced, invited experts. The series, which was started in 1978 by Professor Karl A. Gschneidner Jr., combines, and integrates, both the fundamentals and applications of these elements with two published volumes each year.

Advances in Geophysics, the latest in this critically acclaimed serialized review journal that has published for over 50 years, contains the latest information available in the field. Since 1952, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now in its 57th volume, it contains material still relevant today. It is truly an essential publication for researchers in all fields of geophysics. Volume 57 of Advances in Geophysics consists of three chapters of interest to a broad readership: "Limit Analysis" is reviewed and explained by Leroy and Maillot, who, apart from presenting the theoretical framework, also present their material in a pedagogic way well-suited for teaching; Malehmir et al. present the state-of-the art in high-resolution geophysical imaging of settings prone to natural hazards by explaining and showing a variety of imaging methods in their rich-illustrated contribution; The importance of light snow in relation to understanding weather and climate is presented by Gultepe et al., who highlight the importance of obtaining high-quality measurements and discuss implications for weather and climate simulations.

Developmental Signaling in Plants, the latest volume in The Enzymes series, follows up on the themes discussed in volume 35, notably cell-to-cell and organ-to-organ communication. In addition, it looks at the environmental and hormonal effects on development and the epigenetics on development.

De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction.