There is nothing more essential to our health and wellbeing than breathing: take air in, let it out, repeat 25,000 times a day. Yet, as a species, humans have lost the ability to breathe correctly, with grave consequences.

In Breath, journalist James Nestor travels the world to discover the hidden science behind ancient breathing practices to figure out what went wrong and how to fix it.

Modern research is showing us that making even slight adjustments to the way we inhale and exhale can:

• improve our exercise techniques
• restore healthy sleep patterns and minimise snoring
• halt allergies, asthma and even autoimmune disease

Drawing on thousands of years of ancient wisdom and cutting-edge studies, Breath is full of revelations, turning what we thought we knew about our most basic biological function on its head.

You will never breathe the same again.

Codon-based models of evolution are a relatively new addition to the toolkit of computational biologists, and in recent years remarkable progress has been made in this area. The study of evolution at the codon level captures information contained in both amino acid and synonymous DNA substitutions. By combining these two types of information, codon analyses are more powerful than those of either amino acid or DNA evolution alone. This is a clear benefit for most evolutionary analyses, including phylogenetic reconstruction, detection of selection, ancestral sequence reconstruction, and alignment of coding DNA. Despite the theoretical advantages of codon based models, their relative complexity delayed their widespread use. Only in recent years, when large-scale sequencing projects produced sufficient genomic data and computational power increased, did their usage become more common. In Codon Evolution, leading researchers in the field of molecular evolution provide the latest insights from codon-based analyses of genetic sequences. The first part of the book provides comprehensive coverage of the developments of various types of codon substitution models such as parametric and empirical models used in maximum likelihood as well as Bayesian frameworks. Subsequent chapters examine the use of codon models to infer selection and other applications of codon models to biological systems. The second part of the book focuses on codon usage bias. Both the underlying mechanisms as well as current methods to analyse codon usage bias are presented.

Chemistry is intimately involved in the development of the oldest known civilizations, resulting in a range of chemical technologies that not only continue to be part of modern civilized societies, but are so commonplace that it would be hard to imagine life without them. Such chemical technology has a very long and rich history, in some cases dating back to as early as 20,000 BCE. Chemistry Technology in Antiquity aims to present the discovery, development, and early history of a range of such chemical technologies, with the added goal of including a number of smaller subjects often ignored in the presentation of early chemical technology. While the book does not aim to be a comprehensive coverage of the full range of chemical technologies practiced during antiquity, it provides a feel and appreciation for both the deep history involved with these topics, as well as the complexity of the chemical processes that were being utilized at such a very early time period.

The UK's most trusted A level Mathematics resources With over 900,000 copies sold (plus 1.3 million copies sold of the previous edition), Pearson's own resources for Pearson Edexcel are the market-leading and most trusted for AS and A level Mathematics. Our A level Mathematics Statistics and Mechanics Year 2 Practice Book helps you get exam-ready with confidence and practice at the right pace. Coverage: the practice workbooks cover all Pure, Statistics and Mechanics topics Quantity: the most A level question practice available, with over 2,000 extra questions per book Practice at the right pace: start with the essentials, build your skills with various practice questions to make connections between topics, then apply this to exam-style questions at the end of each chapter Get exam-ready with confidence: differentiated questions including 'Bronze, Silver, Gold' in each chapter, and a mixed problem-solving section for each book, will guide and help you to develop the skills you need for your exams Designed to be used flexibly, the practice books are fully mapped to the scheme of work and textbooks so you can use them seamlessly in and out of the classroom and all year round. Use them lesson by lesson, topic by topic, for homework, revision and more - the choice is yours Great value practice materials that are cheaper than photocopying, saves more time than independently sourcing questions and answers, and are all in one place Pearson Edexcel A level Mathematics Statistics & Mechanics Year 2 Practice Book matches the Pearson Edexcel exam structure and is fully integrated with Pearson Edexcel's interactive scheme of work. Practice books are also available offering the most comprehensive and flexible AS/A level Maths practice with over 2000 extra questions. Pearson's revision resources are the smart choice for those revising for Pearson Edexcel AS and A level Mathematics - there is a Revision Workbook for exam practice and a Revision Guide for classroom and independent study. Practice Papers Plus+ books contain additional full length practice papers, so you can practice answering questions by writing straight into the book and perfect your responses with targeted hints, guidance and support for every question, including fully worked solutions.

Our revision resources are the smart choice for those revising for AQA AS/A Level Chemistry. This book will help you to: * Consolidate your revision with topic- and exam-based formats * Check your understanding with worked examples * Build your confidence with Grade boosters and guided questions * Avoid common misconceptions and pitfalls with helpful tips throughout * Develop your exam technique with exam-style questions and answers. (Full worked solutions available online.)

This is a book written primarily for graduate students and early researchers in the fields of Analysis and Partial Differential Equations (PDEs). Coverage of the material is essentially self-contained, extensive and novel with great attention to details and rigour. The strength of the book primarily lies in its clear and detailed explanations, scope and coverage, highlighting and presenting deep and profound inter-connections between different related and seemingly unrelated disciplines within classical and modern mathematics and above all the extensive collection of examples, worked-out and hinted exercises. There are well over 700 exercises of varying level leading the reader from the basics to the most advanced levels and frontiers of research. The book can be used either for independent study or for a year-long graduate level course. In fact it has its origin in a year-long graduate course taught by the author in Oxford in 2004-5 and various parts of it in other institutions later on. A good number of distinguished researchers and faculty in mathematics worldwide have started their research career from the course that formed the basis for this book.

Why are some countries better than others at science and technology (S&T)? Written in an approachable style, The Politics of Innovation provides readers from all backgrounds and levels of expertise a comprehensive introduction to the debates over national S&T competitiveness. It synthesizes over fifty years of theory and research on national innovation rates, bringing together the current political and economic wisdom, and latest findings, about how nations become S&T leaders. Many experts mistakenly believe that domestic institutions and policies determine national innovation rates. However, after decades of research, there is still no agreement on precisely how this happens, exactly which institutions matter, and little aggregate evidence has been produced to support any particular explanation. Yet, despite these problems, a core faith in a relationship between domestic institutions and national innovation rates remains widely held and little challenged. The Politics of Innovation confronts head-on this contradiction between theory, evidence, and the popularity of the institutions-innovation hypothesis. It presents extensive evidence to show that domestic institutions and policies do not determine innovation rates. Instead, it argues that social networks are as important as institutions in determining national innovation rates. The Politics of Innovation also introduces a new theory of "creative insecurity" which explains how institutions, policies, and networks are all subservient to politics. It argues that, ultimately, each country's balance of domestic rivalries vs. external threats, and the ensuing political fights, are what drive S&T competitiveness. In making its case, The Politics of Innovation draws upon statistical analysis and comparative case studies of the United States, Japan, South Korea, China, Taiwan, Thailand, the Philippines, Argentina, Brazil, Mexico, Canada, Turkey, Israel, Russia and a dozen countries across Western Europe.

Well-structured and adopting a pedagogical approach, this self-contained monograph covers the fundamentals of scanning probe microscopy, showing how to use the techniques for investigating physical and chemical properties on the nanoscale and how they can be used for a wide range of soft materials. It concludes with a section on the latest techniques in nanomanipulation and patterning. This first book to focus on the applications is a must-have for both newcomers and established researchers using scanning probe microscopy in soft matter research. From the contents: * Atomic Force Microscopy and Other Advanced Imaging Modes * Probing of Mechanical, Thermal Chemical and Electrical Properties * Amorphous, Poorly Ordered and Organized Polymeric Materials * Langmuir-Blodgett and Layer-by-Layer Structures * Multi-Component Polymer Systems and Fibers * Colloids and Microcapsules * Biomaterials and Biological Structures * Nanolithography with Intrusive AFM Tipand Dip-Pen Nanolithography * Microcantilever-Based Sensors

Clusters - regional concentrations of related firms and organizations - are seen as being an important element of economic growth and innovation. But there is little understanding of how clusters come into existence, and little guidance provided on the role of policies that are conducive to the formation of clusters. Cluster Genesis focuses on these early origins of clusters. The case histories of well-known, established clusters, as well as more recently-developed clusters are discussed, including: The Hollywood motion picture cluster, Silicon Valley, Boston and San Francisco biotech regions, The Biotech industry in China, Medicon Valley in Scandinavia, The Irish ITC sector. Leading scholars contribute chapters examining cluster genesis, the divergent processes by which clusters arise, how multinationals contribute to cluster development, and how economic development policy may promote or hinder cluster genesis. Cluster Genesis uses a variety of methodological perspectives, examines a range of policy options, and draws on a number of rich case histories, and will be key reading for academics, researchers, and students of Economics, Innovation, Sociology, Geography, and Management Studies, as well as economic development officials and policy makers.

For courses in introductory calculus-based physics. A research-driven approach to physics Physics for Scientists and Engineers incorporates Physics Education Research and cognitive science best practices that encourage conceptual development, problem-solving skill acquisition, and visualization. Knight stresses qualitative reasoning through physics principles before formalizing physics mathematically, developing student problem-solving skills with a systematic, scaffolded approach. The text presents a finely tuned, practical introduction to physics with problems that relate physics to everyday life and includes models, modeling, and advanced topics. With the 5th Edition, new and expanded media and assessments in Mastering and the Pearson eText provide fully integrated print and digital resources for both the active and traditional classroom. New content includes key topics such as Entropy quantitatively, Viscosity and Poiseuille’s Equation, and Carnot Efficiency details. This title is also available digitally as a standalone Pearson eText, or via Mastering Physics, which includes the Pearson eText. Contact your Pearson rep for more information. Mastering® empowers you to personalize learning and reach every student. This flexible digital platform combines trusted content with customizable features so you can teach your course your way. And with digital tools and assessments, students become active participants in their learning, leading to better results. Learn more about Mastering Physics. Pearson eText is an easy-to-use digital textbook available within Mastering Physics that lets students read, highlight, take notes, and review key vocabulary all in one place. For instructors not using Mastering Physics, Pearson eText can also be adopted on its own as the main course material. Learn more about Pearson eText.

The UK's most trusted A level Mathematics resources With over 900,000 copies sold (plus 1.3 million copies sold of the previous edition), Pearson's own resources for Pearson Edexcel are the market-leading and most trusted for AS and A level Mathematics. This book covers all the content needed for the optional Edexcel AS and A level Further Mechanics 1 exams Enhanced focus on problem-solving and modelling, as well as supporting the large data set and calculators Packed with worked examples with guidance, lots of exam-style questions, practice papers, and plenty of mixed and review exercises Full worked solutions to every question available free and online for quick and easy access. Plus free additional online content with GeoGebra interactives and Casio calculator tutorials Practice books also available offering the most comprehensive and flexible AS/A level Maths practice with over 2000 extra questions Includes access to an online digital edition (valid for 3 years once activated) Pearson Edexcel AS and A level Further Mathematics Further Mechanics 1 Textbook + e-book matches the Pearson Edexcel exam structure and is fully integrated with Pearson Edexcel's interactive scheme of work. All of the books in this series focus on problem-solving and modelling, as well as supporting the large data set and calculators. They are packed with worked examples with guidance, lots of exam-style questions, practice papers, and plenty of mixed and review exercises. There are full worked solutions to every question available free and online for quick and easy access. You will also have access to lots of free additional online content with GeoGebra interactives and Casio calculator tutorials. There are separate Pure and Applied textbooks for AS and A level Maths, and a textbook per option for AS and A level Further Maths. Practice books are also available offering the most comprehensive and flexible AS/A level Maths practice with over 2000 extra questions. Pearson's revision resources are the smart choice for those revising for Pearson Edexcel AS and A level Mathematics - there is a Revision Workbook for exam practice and a Revision Guide for classroom and independent study. Practice Papers Plus+ books contain additional full length practice papers, so you can practice answering questions by writing straight into the book and perfect your responses with targeted hints, guidance and support for every question, including fully worked solutions.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

Increased energy prices and the growing attention on global warming are motivating the creation of economically viable alternatives to fossil fuels. Nanotechnologies have been recognized as one effective approach to solve energy problems. Therefore, to promote the improvement of research and to foster professional collaboration among researchers in energy-related nanotechnologies, we organized a symposium on "Nanotechnology for a Sustainable Energy Economy" as a part of the 243rd American Chemical Society National Meeting, which took place March 25-29, 2012 in San Diego, California, USA. Forty-four contributors from 12 countries presented their research works from industrial, university, and national laboratories in nanotechnology areas related to energy and fuel technologies. This ACS Symposium Series book was developed from this symposium. This book presents a very useful and readable collection of reviews and research papers in nanotechnologies for energy conversion, storage, and utilization, offering new results which are sure to be of interest to researchers, students, and engineers in the field of nanotechnologies and energy. The book focuses on the following topics: Li batteries (Chapters 1-4), supercapacitors (Chapter 5), dye-sensitized solar cells (Chapter 6), photocatalysis (Chapters 7-9), fuel cells (Chapter 10), electrocatalysis (Chapter 11), and electron beam lithography (Chapter 12). All 12 chapters were recruited from oral presentations at the symposium.

From the pocket dosemeter and the photographic emulsion to the superheated drop detector and the single particle calorimeter - such is the wide range of detectors for nuclear radiation in this textbook. Emphasis is placed on simple but thorough explanations of the underlying physics for each detector and on the applications to which these detectors can be put. Introductions to the types of radiations concerned and their interaction with matter lead to descriptions of well-established devices such as ionization chambers, proportional and Geiger counters, scintillation counters and semiconductor detectors, and other more recent types such as semiconductor drift chambers and dark matter detectors. A separate chapter discusses sources of noise and their influence on the energy resolution achievable with detector systems, and another the electronics used with radiation detectors. This book has been written by two university physicists who have worked and taught in the field for many years. It is intended for final-year students and new postgraduates as well as all established workers who use sources of ionizing radiation.