In 1997, Dr Marie Cassidy arrived in Dublin from Glasgow. There to discuss a possible deputy state pathologist post with Professor John Harbison, instead she was whisked by police escort to a Grangegorman murder scene. There was no turning back. She became Ireland's State Pathologist from 2004 until 2018, her image synonymous with breaking news of high-profile cases - a trusted figure in turbulent times. Here, with the scalpel-like precision and calm authority of her trade, Marie shares her remarkable personal journey from working-class Scotland into the world of forensic pathology, describing in candid detail the intricate processes central to solving modern crime. She recounts her work following the tragic deaths of Rachel O'Reilly, Siobhan Kearney, Robert Holohan, Tom O'Gorman and others - along with the Stardust exhumations and lesser known cases from her long career - outlining the subtle methods by which pathology and the justice system meet. Beyond the Tape is a unique behind-the-scenes journey into the mysteries of unexplained and sudden death - by turns poignant, stark and deeply compelling.

A uniquely practical DSP text, this book gives a thorough understanding of the principles and applications of DSP with a minimum of mathematics, and provides the reader with an introduction to DSP applications in telecoms, control engineering and measurement and data analysis systems.
The new edition contains:
- Expanded coverage of the basic concepts to aid understanding
- New sections on filter sysnthesis, control theory and contemporary topics of speech and image recognition
- Full solutions to all questions and exercises in the book
- A complete on-line resource
The on-line resource offers instructors and students complete lecture notes, lecture videos, PowerPoint slides for presentations, final exams and solutions, project exercises, URLs to DSP applet experiment animations and e-meeting software for direct communication with the authors.
Assuming the reader already has some prior knowledge of signal theory, this textbook will be highly suitable for undergraduate and postgraduate students in electrical and electronic engineering taking introductory and advanced courses in DSP, as well as courses in communications and control systems engineering. It will also prove an invaluable introduction to DSP and its applications for the professional engineer.
- Expanded coverage of the basic concepts to aid understanding, along with a wide range of DSP applications
- New textbook features included throughout, including learning objectives, summary
sections, exercises and worked examples to increase accessibility of the text
- Full solutions to all questions and exercises included in the book, with extra resources on-line

Infinite Words is an important theory in both Mathematics and Computer Sciences. Many new developments have been made in the field, encouraged by its application to problems in computer science. Infinite Words is the first manual devoted to this topic.
Infinite Words explores "all" aspects of the theory, including Automata, Semigroups, Topology, Games, Logic, Bi-infinite Words, Infinite Trees and Finite Words. The book also looks at the early pioneering work of Buchi, McNaughton and Schutzenberger.
Serves as both an introduction to the field and as a reference book.
Contains numerous exercises desgined to aid students and readers.
Self-contained chapters provide helpful guidance for lectures.

A combination of population growth, public health failures, environmental degradation and rapid global transportation has resulted in a world that is at increasing risk to vectorborne and other infectious diseases. A large percentage of emerging diseases are vectorborne and over one-third of the agents on the list of greatest concern from bioterrorism are vectorborne. Many of these diseases are viral that have no effective drug or vaccine treatments. Drug and insecticide resistance is now common and has greatly compromised our ability to provide effective and affordable control. Parasitic diseases, including malaria, leishmmaniasis and African trypanosomiasis are likewise increasing in many parts of the world. Control programs for onchocerciasis and to some extent filariasis are reducing the impact of these diseases, largely due to the availability of filaricides such as ivermectin. Chagas disease has also declined significantly through home improvements and indoor insecticide application against the domicilary kissing bug vectors.
Despite these gains, this tend has not been sustainable. Instead, infectious disease is now responsible for greater than 25% of all deaths and nearly 50% of premature deaths among those under 45 years of age, and 63% for children less than 4 years of age. A significant proportion of these deaths is attributed to vectorborne diseases, particularly from malaria ( 11%). Indeed, more that 1 million people are killed annually by malaria, about 3000 per day. It is estimated that 700,000 children under the age of 5 die of malaria and at least 300 million are ill due to malaria each year. In response, the American Institute of Medicine (2003) has called for a renewed effort to rebuild public health infrastructures needed to conduct disease surveillance and vector control programs and to increase research to provide improved pesticides and their use, new repellents, new biopestcides and biocontrol agents to augment pesticidal control, as well as novel strategies to interrupt pathogen transmission.
With these goals in mind, we convened the first vector control symposium as part of the scientific program of the 3rd Pan-Pacific Conference of Pesticide Science in 2003. Five years after (2008), we re-convened this expanded topic at the 4th Pan-Pacific Conference on Pesticide Science and the scientific presentations made over two days comprise this current volume, Advances in Human Vector Control. The book covers two major areas: 1) Current Status and Control Practices, covering malaria, dengue, Chagas, human lice, cockroach and house dust mite issues; and 2) Novel Approaches and Resistance Management of these diseases. Chapters are provided by internationally-recognized experts who are actively involved in vector control and management, providing an up to date summary of this critically important area of public health. The effective use of novel control strategies is stressed and the status of recently acquired genomic approaches is critically reviewed.

Galvani's Spark chronicles the gradual understanding of the nerve impulse which is the basis of all thoughts, sensations and actions. The story begins with Luigi Galvani's chance observation of a spark from a friction machine causing a frog's leg to twitch from across the room. The accurate recording and the understanding of the properties of the nerve fiber membrane that makes the impulse possible became the objectives of neuroscientists for over 200 years.
The author, Alan J. McComas finely interweaves the stories, the challenges, and the controversies of the most prominent figures in neuroscience, from the histological descriptions of nerve cells by Cajal to the discovery of a three-dimensional structure of ion channels in cell membranes by MacKinnon. Along the way he details the first recordings of the impulse with a cathode ray oscilloscope by Gasser and Erlanger, Adrian's discovery that stimulus intensity is coded by the frequency of nerve impulses, and Hodgkin and Huxley's brilliant voltage clamp experiments, amongst many others.
The recognition by Galvani that muscles and nerves have an electrical component triggered the field of neurophysiology and in turn has produced some of the greatest discoveries in neuroscience. 16 investigators of the nerve impulse went on to win or share Nobel prizes and this book not only emphasizes their work but also traces their brilliant careers. For anyone interested in the nervous system and the history of neuroscience, Galvani's Spark: The Story of the Nerve Impulse is essential reading.

This book is concerned with two major industrial minerals: Lithium and Calcium Chloride. The geology of their deposits is first reviewed, along with discussions of most of the major deposits and theories of their origin. The commercial mining and processing plants are next described, followed by a review of the rather extensive literature on other proposed processing methods. The more important uses for lithium and calcium chloride are next covered, along with their environmental considerations. This is followed by a brief review of the production statistics for each industry, and some of their compounds' phase data and physical properties.
- Describes the chemistry, chemical engineering, geology and mineral processing aspects of lithium and calcium chloride
- Collects in one source the most important information concerning these two industrial minerals
- Presents new concepts and more comprehensive theories on their origin

What happens when the Dalai Lama meets with leading physicists and a historian? This book is the carefully edited record of the fascinating discussions at a Mind and Life conference in which five leading physicists and a historian (David Finkelstein, George Greenstein, Piet Hut, Arthur Zajonc, Anton Zeilinger, and Tu Weiming) discussed with the Dalai Lama current thought in theoretical quantum physics, in the context of Buddhist philosophy. A contribution to the science-religion interface, and a useful explanation of our basic understanding of quantum reality, couched at a level that intelligent readers without a deep involvement in science can grasp. In the tradition of other popular books on resonances between modern quantum physics and Zen or Buddhist mystical traditions--notably The Dancing Wu Li Masters and The Tao of Physics, this book gives a clear and useful update of the genuine correspondences between these two rather disparate approaches to understanding the nature of reality.

This volume is an attempt to educate, to provide a source of information, knowledge, and wisdom to the person who has spent so much time and energy on his or her schooling. The Council for Chemical Research (CCR) and the American Chemical Society (ACS) have both spent considerable effort over the past decades focusing on how to ensure that graduate education in the chemical sciences remains at the absolute highest caliber, and produces the best possible professionals. In spite of notable efforts from both organizations to prepare graduate students for the professional world, neither has specifically asked what a person needs to be successful once they have both the Ph.D. and the first job in hand. Put succinctly, there is much more to being successful in a career in chemistry than just the hard-earned Ph.D. degree. What You Need for the First Job, Besides the Ph.D. in Chemistry is based on a symposium of the same name held at the 246th National Meeting of the American Chemical Society, which took place in Indianapolis, Indiana in September, 2013. This book is the result of seeds that were planted during numerous informal conversations at the annual meetings of the CCR, as well as during such discussions at national and regional meetings of the ACS, and at the ACS employment clearing houses. The authors felt that the same intense focus a person needs to earn a Ph.D. might actually work against the attention to other details needed in order to be successful once he or she has obtained a position. Leaders want to ensure that new hires are working effectively toward tenure, are quickly becoming productive members of their corporate team, or are well integrated into their government laboratory research group. While it is easy to lump factors other than technical competence in one's job under the term "soft skills," this is an oversimplification. This book represents an attempt to have voices from all three pillars of the chemical enterprise - academia, industry, and government laboratories - heard in terms of relating what is important for their newly hired Ph.D.-holders. What You Need for the First Job, Besides the Ph.D. in Chemistry will be a valuable resource for first-time job seekers, as well as those with aspirations of a future career in the chemical sciences.

Together with other volumes in this series, Volume 56 presents thoughtful and forward-looking articles on developmental biology and developmental medicine.
Reviews include:
* Selfishness in moderation: evolutionary success of the yeast plasmid
* Nongenomic actions of androgen in sertoli cells
* Regulation of chromatin structure and gene activity by Poly(ADP-ribose) polymerases
* Centromeres and Kinetochores, Who Needs 'Em? The Role of Non-centromeric Chromatin in Spindle Assembly
* Modeling Cardiogenesis: The Challenges and Promises of 3D Reconstruction
* Plasmid and Chromosome Traffic Control: How ParA and ParB Drive Partition
The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage

Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies.
*Methods in Liposome Preparation
*Physiochemical Characterization of Liposomes

The authors of this book argue that there is a great divide between species that makes extrapolation of biochemical research from one group to another utterly invalid. In their previous book, "Sacred Cows and Golden Geese: The Human Cost of Experiments on Animals", the Greeks showed how an amorphous but insidious network of drug manufacturers, researchers dependent on government grants to earn their living, even cage-manufacurers - among others benefiting from "white-coat welfare" - have perpetuated animal research in spite of its total unpredictability when applied to humans. (Cancer in mice, for example, has long been cured. Chimps live long and relatively healthy lives with AIDS. There is no animal form of Alzheimer's disease.) In doing so, the Greeks aimed to blow the lid off the "specious science" we have been culturally conditioned to accept. Taking these revelations one step further, this book uses accessible language to provide the scientific underpinning for the Greeks' philosophy of "do no harm to any animal, human or not," by examining paediatrics, diseases of the brain, new surgical techniques, in vitro research, the Human Genome and Proteome Projects, an array of scien

This third volume of NMR Spectroscopy in the Undergraduate Curriculum continues the work we started with the first and second volumes in providing effective approaches for using nuclear magnetic resonance spectrometers as powerful tools for investigating a wide variety of phenomena at the undergraduate level. This volume focuses on upper-level courses and NMR spectroscopy across the curriculum. The applications and strategies in this volume will be helpful to those who are looking to transform their curriculum by integrating more NMR spectroscopy, to those who might not have considered NMR spectroscopy as a tool for solving certain types of problems, or for those seeking funding for a new or replacement NMR spectrometer.

The powerful potential of digital media to engage citizens in political actions has now crossed our news screens many times. But scholarly focus has tended to be on "networked," anti-institutional forms of collective action, to the neglect of advocacy and service organizations. This book investigates the changing fortunes of the citizen-civil society relationship by exploring how social changes and innovations in communication technology are transforming the information expectations and preferences of many citizens, especially young citizens. In doing so, it is the first work to bring together theories of civic identity change with research on civic organizations. Specifically, it argues that a shift in "information styles" may help to explain the disjuncture felt by many young people when it comes to institutional participation and politics. The book theorizes two paradigms of information style: a dutiful style, which was rooted in the society, communication system and citizen norms of the modern era, and an actualizing style, which constitutes the set of information practices and expectations of the young citizens of late modernity for whom interactive digital media are the norm. Hypothesizing that civil society institutions have difficulty adapting to the norms and practices of the actualizing information style, two empirical studies apply the dutiful/actualizing framework to innovative content analyses of organizations' online communications-on their websites, and through Facebook. Results demonstrate that with intriguing exceptions, most major civil society organizations use digital media more in line with dutiful information norms than actualizing ones: they tend to broadcast strategic messages to an audience of receivers, rather than encouraging participation or exchange among an active set of participants. The book concludes with a discussion of the tensions inherent in bureaucratic organizations trying to adapt to an actualizing information style, and recommendations for how they may more successfully do so.

Artificial intelligence (AI) is often discussed as something extraordinary, a dream-or a nightmare-that awakens metaphysical questions on human life. Yet far from a distant technology of the future, the true power of AI lies in its subtle revolution of ordinary life. From voice assistants like Siri to natural language processors, AI technologies use cultural biases and modern psychology to fit specific characteristics of how users perceive and navigate the external world, thereby projecting the illusion of intelligence. Integrating media studies, science and technology studies, and social psychology, Deceitful Media examines the rise of artificial intelligence throughout history and exposes the very human fallacies behind this technology. Focusing specifically on communicative AIs, Natale argues that what we call "AI" is not a form of intelligence but rather a reflection of the human user. Using the term "banal deception," he reveals that deception forms the basis of all human-computer interactions rooted in AI technologies, as technologies like voice assistants utilize the dynamics of projection and stereotyping as a means for aligning with our existing habits and social conventions. By exploiting the human instinct to connect, AI reveals our collective vulnerabilities to deception, showing that what machines are primarily changing is not other technology but ourselves as humans. Deceitful Media illustrates how AI has continued a tradition of technologies that mobilize our liability to deception and shows that only by better understanding our vulnerabilities to deception can we become more sophisticated consumers of interactive media.

This book presents the first comprehensive description of the lithic assemblages from Qafzeh Cave, one of only two Middle Paleolithic sites in the Levant that has yielded multiple burials of early anatomically modern Homo sapiens (AMHs). The record from this region raises the question of possible long-term temporal overlap between early AMHs and Neanderthals. For this reason, Qafzeh has long been one of the pivotal sites in debates on the origins of AMHs and in attempts to compare and contrast the two species' adaptations and behavior.
Although the hominin fossils from the site were published years ago, until now the associated archaeological assemblages were incompletely described, often leading to conflicting interpretations. This monograph includes a thorough technological analysis of the lithic assemblages, incorporated in their geological and sedimentological contexts. This description serves as a springboard for regional comparisons as well as a more general discussion about Middle Paleolithic behavior, which is relevant to important and as yet unresolved questions on the origins of "modern" behavior patterns.
The volume includes a wide-ranging and up-to-date bibliography that provides the middle-range for discussing the ecological context and behavioral complexity of the Middle Paleolithic period, and ends with some thought-provoking conclusions about the dynamic human interations that existed in the region during this time.

This book should be of value to anyone interested in bird evolution and taxonomy, biogeography, distributional history, dispersal and migration patterns. It provides an up-to-date synthesis of current knowledge on species formation, and the factors influencing current distribution patterns. It draws heavily on new information on Earth history, including past glacial and other climatic changes, on new developments in molecular biology and palaeontology, and on recent studies of bird distribution and migration patterns, to produce a coherent account of the factors that have influenced bird species diversity and distribution patterns worldwide.
Received the Best Bird Book of the Year award for 2004 from British Birds magazine.
* Winner of the British Birds/British Trust for Ornithology, Bird Book of the Year 2004
* The first book to deal comprehensively with bird speciation and biogeography
* Up-to-date synthesis of new information
* Clearly written
* No previous book covers the same ground
* Many maps and diagrams
* Makes difficult and widely scattered information accessible and easily understood
* A sound base for future research
* Takes full account of recent developments in molecular biology

Viruses that infect plants are responsible for reduction in both yield and quality of crops around the world, and thus are of great economic importance. This has provided the impetus for the extensive research into the molecular and cellular biology of these pathogens and into their interaction with their plant hosts and their vectors. However, interest in plant viruses extends beyond their ability to damage crops. Many plant viruses - for example, tobacco mosaic virus - have been used as model systems to provide basic understanding of how viruses express genes and replicate. Others permitted the elucidation of the processes underlying RNA silencing, now recognized as a core epigenetic mechanism underpinning numerous areas of biology. This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. The book concludes with two chapters on biotechnological applications of plant viruses. Throughout, the focus is on the most recent, cutting-edge research, making this book essential reading for everyone working with plant viruses.

Microbiological risk assessment (MRA) is one of the most important recent developments in food safety management. Adopted by Codex Alimentarius and many other international bodies, it provides a structured way of identifying and assessing microbiological risks in food. Edited by two leading authorities, and with contributions by international experts in the field, Microbiological risk assessment provides a detailed coverage of the key steps in MRA and how it can be used to improve food safety.
The book begins by placing MRA within the broader context of the evolution of international food safety standards.
Part one introduces the key steps in MRA methodology. A series of chapters discusses each step, starting with hazard identification and characterisation before going on to consider exposure assessment and risk characterisation. Given its importance, risk communication is also covered. Part two then considers how MRA can be implemented in practice. There are chapters on implementing the results of a microbiological risk assessment and on the qualitative and quantitative tools available in carrying out a MRA. It also discusses the relationship of MRA to the use of microbiological criteria and another key tool in food safety management, Hazard Analysis and Critical Control Point (HACCP) systems.
With its authoritative coverage of both principles and key issues in implementation, Microbiological risk assessment in food processing is a standard work on one of the most important aspects of food safety management.
Provides a detailed coverage of the key steps in microbiological risk assessment (MRA) and how it can be used to improve food safetyPlaces MRA within the broader context of the evolution of international food safety standardsIntroduces the key steps in MRA methodology, considers exposure assessment and risk characterisation, and covers risk communication

Transnational Cooperation: An Issue-Based Approach presents an analysis of transnational cooperation or collective action that stresses basic concepts and intuition. Throughout the book, authors Clint Peinhardt and Todd Sandler identify factors that facilitate and/or inhibit such cooperation. The first four chapters lay the analytical foundations for the book, while the next nine chapters apply the analysis to a host of exigencies and topics of great import. The authors use elementary game theory as a tool for illustrating the ideas put forth in the text. Game theory reminds us that rational actors (for example, countries, firms, or individuals) must account for the responses by other rational actors. The book assumes no prior knowledge of game theory; all game-theoretic concepts and analyses are explained in detail to the reader. Peinhardt and Sandler also employ paired comparisons in illustrating the book's concepts. The book is rich in applications and covers a wide range of topics, including superbugs, civil wars, money laundering, financial crises, drug trafficking, terrorism, global health concerns, international trade liberalization, acid rain, leadership, sovereignty, and many others. Students, researchers, and policymakers alike have much to gain from Transnational Cooperation. It is a crossover book for economics, political science, and public policy.

Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions.
Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes.
An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool.
Key Features
* The first comprehensive book on the roles of histidine kinases in cells
* 23 in-depth chapters written by leading experts in the field
* Describes the most recent advances in the field of signal transduction

Solid state physics is the branch of physics that is primarily devoted to the study of matter in its solid phase, especially at the atomic level. This prestigious serial presents timely and state-of-the-art reviews pertaining
to all aspects of solid state physics.
This latest volume in the series is devoted to the science underpinning two cutting edge areas: protein crystallization and semiconductor nanostructures. The extended and very complete review by E. Runge was awarded this year's Karl-Scheel Prize for "the outstanding publication by a young physicist from Berlin."

This book presents a brief compilation of results from nearly a century of research on the globular star clusters in the Andromeda Galaxy (M31). It explores the techniques and limitations of the observations, the successes and challenges of the models, and the paradigm for the formation of M31 that has gradually emerged. These results will eventually be superseded by new data, better analysis techniques, and more complex models. However, the emphasis of this book is on the techniques, thought processes, and connections with other studies.

This book will explore our forests as the most readily available and renewable source of carbon as well as the building block of chemicals, plastics, and pharmaceuticals as the next 100 years gradually push consumers toward alternate sources of chemicals. Meeting these needs from trees requires that new chemistry be developed so that plant materials is converted to commodity chemicals. This focused discussion on ongoing global efforts at creativity using forest and biomass based renewable materials will include six different mechanisms for bringing about change on this very innovative topic.