Advances in Applied Microbiology, Volume 102, the latest release in one of the most widely read and authoritative review sources in microbiology, contains comprehensive reviews of the most current research in applied microbiology. This latest release includes specific chapters on a variety of topics, most notably, Twenty-five Years of Investigating the Universal Stress Protein: Structure, function and applications, Fungal Genomes and Genotyping, Fungi in deep subsurface environments, Spore germination in pathogenic fungi, Host sensing by pathogenic fungi, Advances in the Microbial Ecology of Biohydrometallurgy, and The mycosphere and turnover of contaminants, amongst others.

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more.

Advances in Agronomy, Volume 149, the latest release in the series, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

Routley-Meyer Ternary Relational Semantics for Intuitionistic-type Negations examines how to introduce intuitionistic-type negations into RM-semantics. RM-semantics is highly malleable and capable of modeling families of logics which are very different from each other. This semantics was introduced in the early 1970s, and was devised for interpreting relevance logics. In RM-semantics, negation is interpreted by means of the Routley operator, which has been almost exclusively used for modeling De Morgan negations. This book provides research on particular features of intuitionistic-type of negations in RM-semantics, while also defining the basic systems and many of their extensions by using models with or without a set of designated points.

Progress in Medicinal Chemistry, Volume 57, provides a review of eclectic developments in medicinal chemistry, with this volume including chapters on the CaSR field, CFTR modulators in cystic fibrosis, macrocycles, VMAT2 inhibitors, and Big Data in Drug Discovery.

Advances in Clinical Chemistry, Volume 83, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest, most up-to-date technologies related to the field of clinical chemistry, with this release presenting comprehensive updates on Urinary Nucleosides and Deoxynucleosides, Locked Nucleic Acid Technology for Highly Sensitive Detection of Somatic Mutations in Cancer, Liquid Biopsy: From Basic Research to Clinical Practice, Circulating Tumor Cells and Implications of the Epithelial-to-Mesenchymal Transition, and more.

Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Application, Volume 79, highlights the most recent LC-MS evolutions through a series of contributions by world renowned scientists that will lead the readers through the most recent innovations in the field and their possible applications. Many authoritative books on LC-MS are already present in market, describing in detail the different interfaces and their principles of operation. This book focuses more on new trends, starting with the innovations of each technique, to the most progressive challenges of LC-MS.

Nanoparticle Technology Handbook, Third Edition, is an updated and expanded authoritative reference providing both the theory behind nanoparticles and the practical applications of nanotechnology. This third edition features twenty new chapters, providing a reference much broader in scope than the previous edition. Over 140 experts in nanotechnology and/or particle technology contributed to this new edition. The book not only includes the theory behind nanoparticles, but also the practical applications of nanotechnology. It examines future possibilities and new innovations and contains important knowledge on nanoparticle characterization and the effect of nanoparticles on the environment and humans. Nanoparticle technology is a new and revolutionary technology, which is increasingly used in electronic devices and nanomaterials. It handles the preparation, processing, application and characterization of nanoparticles and has become the core of nanotechnology as an extension of conventional fine particle/powder technology. Nanoparticle technology plays an important role in the implementation of nanotechnology in many engineering and industrial fields, including electronic devices, advanced ceramics, new batteries, engineered catalysts, functional paint and ink, drug delivery system, biotechnology, etc., making use of the unique properties of nanoparticles, which are completely different from those of bulk materials.

Handbook of Thermal Analysis and Calorimetry: Recent Advances, Techniques and Applications, Volume Six, Second Edition, presents the latest in a series that has been well received by the thermal analysis and calorimetry community. This volume covers recent advances in techniques and applications that complement the earlier volumes. There has been tremendous progress in the field in recent years, and this book puts together the most high-impact topics selected for their popularity by new editors Sergey Vyazovkin, Nobuyoshi Koga and Christoph Schick-all editors of Thermochimica Acta. Among the important new techniques covered are biomass conversion; sustainable polymers; polymer nanocompsoties; nonmetallic glasses; phase change materials; propellants and explosives; applications to pharmaceuticals; processes in ceramics, metals, and alloys; ionic liquids; fast-scanning calorimetry, and more.

Professor Steve Peters is a Consultant Psychiatrist and author of the bestselling self-help book, The Chimp Paradox. He has years of experience as a clinician, an educator and has worked with some of the world's most successful athletes. His new book 'A Path through the Jungle' will help you to become robust and resilient. Professor Peters explains complex neuroscience in straightforward terms with his Chimp Management Mind Model Robust: Becoming robust means having plans in place to manage your own mind and whatever situations you meet in life. Resilient: is being able to bounce back and manage the challenges of life. Resilience is a skill. A Path through the Jungle offers a structured programme with exercises and practical real-life examples. This book will help you to improve in areas such as: * Managing stress and anxiety * Improved relationships * Emotional management * Grief and loss * Self-confidence * Peace of mind * Happiness * Managing stress

The Alkaloids, Volume 79 is the latest in a series that has covered the topic for more than 60 years. It is considered to be the leading book series in the field of alkaloid chemistry, with more than 70 volumes that cover all aspects of alkaloids, including their chemistry, biology and pharmacology. Each release includes high-quality, timeless reviews written by renowned experts in the field, with this release focusing on pyrrolizidine alkaloids.

Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more.

Nonlinear Differential Problems with Smooth and Nonsmooth Constraints systematically evaluates how to solve boundary value problems with smooth and nonsmooth constraints. Primarily covering nonlinear elliptic eigenvalue problems and quasilinear elliptic problems using techniques amalgamated from a range of sophisticated nonlinear analysis domains, the work is suitable for PhD and other early career researchers seeking solutions to nonlinear differential equations. Although an advanced work, the book is self-contained, requiring only graduate-level knowledge of functional analysis and topology. Whenever suitable, open problems are stated and partial solutions proposed. The work is accompanied by end-of-chapter problems and carefully curated references.

Studies in Natural Products Chemistry, Volume 56 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

The identification and quantification of the widespread occurrence of trace organic chemicals at minute concentrations in the aqueous environment impacted by human activities is a result of rapid advances in environmental analytical chemistry. The body of knowledge regarding the characterization, fate and transport of these chemicals of emerging concern (CECs) in the natural water environment and engineered water treatment processes, as well as their toxicity, has grown substantially over the last two decades. Recently, the focus in the environmental chemistry community has shifted from these CEC parent compounds to the fate, transport, and toxicity of transformation products, which are generated through abiotic and biotic mechanisms in natural systems and during engineered advanced water treatment processes. This two-part book focuses on the studies and recent advancements towards the development of more harmonized strategies and workflows using non-target and suspects screening methods, including suitable bioassay approaches to assess the overall relevance of transformation products. Volume I covers the relevance of transformation products and international strategies to manage CECs, new methods for a comprehensive assessment of transformation products, and the fate and transport of transformation products in natural systems. This book is ideal for environmental scientists and engineers, particularly chemists, environmental engineers, public health officials, regulators, other chemistry-related professionals, and students.

WNT Signaling, Volume 153, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series provides readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, along with insights into how this knowledge may be applied to understand and ameliorate human disease. Each volume is edited by an internationally recognized expert who selects contributors at the forefront of a field.

Novel Electronic Structure Theory: General Innovations and Strongly Correlated Systems, Volume 76, the latest release in the Advances in Quantum Chemistry series presents work and reviews of current work in quantum chemistry (molecules), but also includes scattering from atoms and solid state work of interest in physics. Topics covered in this release include the Present Status of Selected Configuration Interaction with Truncation Energy Error, Recent Developments in Asymptotic Expansions from Numerical Analysis and Approximation Theory, The kinetic energy Pauli enhancement factor and its role in determining the shell structure of atoms and molecules, Numerical Hartree-Fock and Many-Body Calculations for Diatomic Molecules, and more.

Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.

Insect Epigenetics, Volume 53 provides readers with the latest interdisciplinary reviews on the topic. Updated chapters in this new release include Epigenetics in insects: Mechanisms, ecological outcomes, and evolutionary consequences, Nutrition and epigenetic change in insects, microRNAs in Drosophila insulin regulation, Epigenetic regulation of longevity in insects, Epigenetic influences on diapause, the Impact of parasites on epigenetics of their insect hosts, The molecular physiology of locust swarming behavior, The future of environmental epigenetics: insights using the clonal water-flea model, and. Epigenetics - A hidden target of insecticides. Led by volume editor Heleen Verlinden, this is an essential reference source for entomologists, zoologists, geneticists and insect chemists.

Advances in Agronomy, Volume 143 continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. This latest release brings new and updated information on Soil: The Forgotten Piece of the Water, Food, Energy Nexus, Humin: Its Composition and Importance in Soil Organic Matter, the Effects of Drought Stress on Morpho-Physiological Traits, Biochemical Characteristics, Yield and Yield Components in Different Ploidy Wheat: A Meta-Analysis, and a section on the Delineation of Soil Management Zones for Variable Rate Fertilization - A Review. Each volume in this series contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. This most current release in this highly cited series focuses on such timely topics as novel treatments in immunotherapy in breast cancer, chemokine receptor signaling and the hallmarks of cancer, tumor-targeting antibodies, and a section on mitochondrion and whether they are a common organelle for cell death. As always, readers will find the articles in this series to be of great value, with a high impact and average cited half-life of nine years. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This great resource ranks high amongst scientific journals dealing with cell biology.

Gibbs' Entropic Paradox and Problems of Separation Processes reviews the so-called Gibb's Paradox observed during the mixing of two systems. During the last 150 years, many physicists and specialists in thermodynamics, statistical and quantum mechanics been engaged in the solution of the Gibbs paradox. Many books and journal articles have written on this topic, but a widely accepted answer is still lacking. In this book, the author reviews and analyzes all this data. Based on findings, the book formulates a different approach to this paradox and substantiates it on the basis of physical and statistical principles. The book clearly shows that entropy consists of two parts, static and dynamic. Up to now, entropy has been connected only with the process dynamics. However, the Gibbs paradox is caused by the change in the static component of entropy. Finally, the book includes examples of separation processes and how to optimize them in various fields, including biology, cosmology, crystallography and the social sciences.

Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.

Fundamentals of Quantum Mechanics, Third Edition is a clear and detailed introduction to quantum mechanics and its applications in chemistry and physics. All required math is clearly explained, including intermediate steps in derivations, and concise review of the math is included in the text at appropriate points. Most of the elementary quantum mechanical models-including particles in boxes, rigid rotor, harmonic oscillator, barrier penetration, hydrogen atom-are clearly and completely presented. Applications of these models to selected "real world" topics are also included. This new edition includes many new topics such as band theory and heat capacity of solids, spectroscopy of molecules and complexes (including applications to ligand field theory), and small molecules of astrophysical interest.

Advances in the Study of Behavior, Volume 49 provides users with the latest insights in this ever-evolving field. Users will find new information on a variety of species, including social behaviors in reptiles, the behavioral evidence of felt emotions, a section on developmental plasticity, a chapter on covetable corpses and plastic beetles and the socioecological behavior of burying beetles, and a section on the mechanisms of communication and cognition in chickadees. This volume makes another important contribution to the development of the field by presenting theoretical ideas and research findings to professionals studying animal behavior and related fields. Researchers in a variety of behavioral fields will find this longstanding series, initiated over 40 years ago, to be a go-to resource for the study of animal behavior.