This book is focused on recent progress in the dynamically developing field of controlled/living radical polymerization. It is a sequel to ACS Symposium Series 685, 768, 854, and 944. The volume contains 24 chapters on other controlled/living radical polymerization techniques including kinetics and mechanism of RAFT, DT, NMP, and OMRP, macromolecular architecture by RAFT, DT, and NMP, materials prepared by RAFT and NMP, and industriral aspects of RAFT and NMP.

"Progress in Medicinal Chemistry" provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more.

Extended timely reviews of topics in medicinal chemistryTargets and technologies relevant to the discovery of tomorrow s drugs.Analyses of successful drug discovery programmes"

This book is focused on recent progress in the dynamically developing field of controlled/living radical polymerization. It is a sequel to ACS Symposium Series 685, 768, 854, and 944. Volume 1023 contains 26 chapters on mechanistic, synthetic and materials aspects of ATRP. Volume 1024 contains 24 chapters on other controlled/living radical polymerization techniques.

Levels of mycotoxin contamination in agricultural commodities are regulated in more than 100 countries, and exposure to these naturally occurring toxins presents serious risks to the health of humans and animals with negative impacts to commodity values. This symposium series book presents significant scientific developments in the multifaceted approach to reducing exposure to these naturally occurring toxins. A broad-spectrum of subject matter of the multidisciplinary field of mycotoxin research is conveniently compiled in this single volume, and general themes include prevention, control, exposure, molecular biology, biosynthesis, analytical methodology, and emerging techniques. The book opens with an overview of prevention of mycotoxin production by means of biological control and human exposure to contaminated foods, including tofu, apples, figs, and a broad range of fruits.
The second section focuses on molecular biological approaches to control mycotoxin exposure. Topics covered include genomic approaches, detoxification, structure-activity studies of biosynthetic precursors, and mycotoxin biosynthesis. The success of these strategies is supported by the reduction of mycotoxin occurrence and incidence in foods. Accurate estimates of mycotoxin concentration in foods are important for food safety and wholesomeness.
The final section covers analytical approaches, including sampling plans for foods and dietary supplements, extraction efficiency of mycotoxins from naturally contaminated grains, traditional detection methods such as chromatography/mass spectrometry, and emerging techniques such as the use of molecularly imprinted polymers for purification and isolation and cyclodextrins for fluorescent enhancement of several mycotoxins.

This book brings together the latest perspectives and ideas on teaching modern physical chemistry. It includes perspectives from experienced and well-known physical chemists, a thorough review of the education literature pertaining to physical chemistry, a thorough review of advances in undergraduate laboratory experiments from the past decade, in-depth descriptions of using computers to aid student learning, and innovative ideas for teaching the fundamentals of physical chemistry. This book will provide valuable insight and information to all teachers of physical chemistry.

Aggregation-induced emission (AIE) stands for an intriguing phenomenon in which a series of non-emissive molecules in solutions are induced to emit strongly in the aggregate or solid state. The concept of AIE was first coined by author Ben Zhong Tang in 2001, when he and his co-workers serendipitously discovered that 1-methyl-1,2,3,4,5-pentaphenylsilole was almost non-emissive in ethanol solution but became extremely bright in water-ethanol mixtures. Over the past 15 years, AIE has grown into a research field with high visibility and broad impact across both science and technology. Aggregation-Induced Emission: Materials and Applications summarizes the recent advances in AIE research, ranging from fundamentals, such as design, synthesis, and optical properties of AIE-active molecules, to mechanism studies supported by modeling and experimental investigations, and further to promising applications in the fields of energy, environment, and biology. The topics covered in Volume 2 include: AIE polymers; AIE-induced chirogenesis; Room-temperature phosphorescent AIE molecules; Liquid crystalline AIE molecules; AIE materials for energy devices; New chemo- and biosensors with AIE molecules; Cell structure and function imaging with AIE molecules; and AIE materials in drug delivery and therapy.

New Publication! Based on years of experience and prior publications, the NEW two-volume book, STEM RESEARCH for STUDENTS, is a vital resource for K-12 teachers, higher education faculty, and their students. In Volume Two, students build upon a strong foundation to create original STEM projects: Brainstorm ideas for projects; Analyze and address the safety risks involved in a project; Use the library and Web to expand understanding and develop a valid idea; Conduct a group mini-project which involves readily-available materials in the classroom, on a field site, or at a community location. Use algebra to represent patterns and develop mathematical models; Use statistics to detect the significance of relationships; and Communicate project findings through formal papers, visual presentations, and interactions with peers or judges. STEM Research for Students, Volume 2 is: Student friendly! Each chapter is carefully sequenced and contains a variety of formative assessment tools. Key definitions are included in an appendix. Essential foundational knowledge from Volume 1 is clearly referenced. STEM encompassing! Students have multiple opportunities to make connections by applying information from the various chapters to original projects. Teacher enhanced! Each chapter contains learning objectives and assessment tools checklists or rubrics. Answers to the practice sets are available on a secure Kendall Hunt web site. Standards aligned! All chapters are aligned with the Next Generation Science Standards, Common Core Standards for Mathematics and Literacy in Science and Technical Subjects, and the International Standards for Technology in Education Standards for Students. Available in print and e-Book formats, STEM Research for Students, Volume 2, may be used: As a supplemental text in middle school, high school, and introductory college courses; As core text for research classes and STEM clubs where students are ready to engage in group or individual projects: For pre-service and in-service teachers of science, mathematics, career and technical courses, and gifted students; As a resource for all teachers involved with experiments, engineering designs, mathematical investigations, and competitive STEM projects. The companion volume, STEM Research for Students, Volume 1, is a resource for students to acquire or strengthen the foundational knowledge necessary to engage in an original project.

New Publication! Based on years of experience and prior publications, the NEW two-volume book, STEM RESEARCH for STUDENTS, is a vital resource for K-12 teachers, higher education faculty, and their students. In Volume One, students acquire the fundamentals and apply them to their investigations: Conduct experiments and refine the design and procedures; Construct data tables and graphs, use descriptive statistics, and make sense of an experiment; Meet a human need by designing, building, and testing a model; Communicate findings through reports and interactions with peers; Apply mathematical concepts to data including ratio and proportional relationships, geometry and measurement, algebra, and statistics. STEM Research for Students, Volume 1, is: Student friendly! Chapters contain investigations with readily available materials, explanations of major concepts, practice sets, and formative assessment tools. Use as a sequence or as individual units of study for specific content. STEM encompassing! For each core experiment, students have multiple options for making connections to various scientific disciplines, engineering, and mathematics. Teacher enhanced! Each chapter contains learning objectives and assessment tools checklists or rubrics. Answers to the practice sets are available on a secure Kendall Hunt web site. Standards aligned! All chapters are aligned with the Next Generation Science Standards, Common Core Standards for Mathematics and Literacy in Science and Technical Subjects, and the International Standards for Technology in Education Standards for Students. Available in print and e-Book formats, STEM Research for Students, Volume 1, may be used: As a supplemental text in upper elementary, middle, and senior high classrooms; As a core text for introductory research courses and STEM research clubs; For pre-service and in-service teachers of science, mathematics, career and technical courses, and gifted students; As a resource for all teachers involved with experiments, engineering designs, mathematical investigations, and competitive STEM projects. The companion volume, STEM Research for Students, Volume 2 enables students to build upon this strong foundation and create effective science experiments, engineering designs, and mathematical investigations.

Die skrywer se doelstelling met hierdie publikasie is om die beginsels van sterrekunde toeganklik te maak vir almal, om ‘n teks daar te stel wat bruikbare toeligting vir die amateursterrekundige is en kan dien as voorbereiding vir verdere studie in die sterrekunde.

Van Zyl se eenvoudige, onderhoudende skryfstyl dra verder by tot die boek se toeganklikheid vir sterrekundiges sowel as leke met ‘n besondere belangstelling in die heelal. Deurgaans word gepoog om te verduidelik hoe sterrekundiges te werk gaan. Om begrip te vergemaklik, verskyn ook 11 bladsye bylaes waarin die wiskunde wat gebruik word uit grondbeginsels herlei word. Dit bevat gedetailleerde beskrywings en verduidelikings van die heelal se geheime.

Inligting oor nuwe ontdekkings en teoriee, kleurvolle diagramme en foto’s verhoog die waarde.

Africa has been and continues to be a significant source of medicinal and aromatic plants and botanicals to the world's food, drug, herb and dietary supplement market, and in the past decade numerous African plant materials have established a strong international market presence. This book provides an excellent opportunity to delve into the current and future contributions that African plants can and will continue to make both internal to Africa and on the global stage. This book expertly covers various medicinal plants of African origin and the some of the latest basic and clinical research supporting their ongoing and potential uses in self-care and healthcare. This work also examines various issues and trends in medicinal plants from their uses in Traditional Medicine and ethnobotany, to our modern understanding of the plants chemistry and pharmacognosy, natural products chemistry and applications of medicinal plants, quality control, and models of benefit sharing.

Chirality as an environmental phenomenon was dealt with in a thorough and interesting manner in a series of three symposia entitled "Modern Chiral Pesticides: Enantioselectivity and Its Consequences," sponsored by the Agrochemical Division of the American Chemical Society and held in Washington, DC (2005), Boston, MA (2007) and San Francisco, CA (2010). All three symposia included speakers from industry, government and academia, representing several European countries, China, and the United States. Corresponding to this broad group of countries, institutions and speakers, the range of topics touched on almost all facets of chirality as it is manifested in environmental and human exposure and toxicity. The 40 oral and 20 poster presentations indeed approached comprehensive coverage: analysis of enantiomers and other stereoisomers; preparative separation of enantiomers; stereoselective occurrences of chiral pesticides in environment soil and water and in wildlife and human tissues and fluids; stereoselective degradation and metabolism of chiral pesticides; and stereoselective toxicity.
This book is a result of manuscript contributions by some of the oral and poster presenters to the third symposium in 2010. In addition to symposium participants, invitations were extended to the environmental chiral chemistry community in general, including most of the speakers in the 2005 and 2007 symposia, in an attempt to attain good coverage of this rather broad topic. Thus, this ACS Symposium book will generate many new ideas from interested readers and inform them of useful techniques for experimental exploration of the somewhat exotic, but important, area of chiral chemistry of pesticides.

Fire is a continuing problem around the world and it must be controlled. This ACS Symposium Series volume addresses recent advances in fire retardancy and examines progress that has been made in controlling fires. It focuses on the chemistry of the polymers themselves and how those chemical structures yield particular heat release, thermal decomposition products, and full-scale fire performance. The book consists of 5 sections. First, the Editors produce an overview to put the latest research into perspective. The first third of the book focuses on Nanocomposites and Flame Retardancy and represents the current state of the field. The second third of the book is devoted to Polymer Flammability Measurement and Mechanisms. The remainder of the book will is equally divided between New Flame Retardant Chemistry and Recent Developments in Flame Retardant Materials. Each of the 4 technical sections is preceded by a short overview provided by the editors.

The Nobel Prize is the only scientific prize that has achieved worldwide recognition among the general public. Each year, announcement of the prizes is covered by the national news media, and countries and universities brag about how many Nobel Prize winners they have. As of 2015, 172 individuals have received the Nobel Prize in chemistry. This book explores the reasons why the Nobel Prize has not been awarded to various deserving chemists over the years, and points specifically to eleven deceased chemists in particular who did not receive the Nobel Prize in Chemistry.

Linearity plays a critical role in the study of elementary differential equations; linear differential equations, especially systems thereof, demonstrate a fundamental application of linear algebra. In Differential Equations with Linear Algebra, we explore this interplay between linear algebra and differential equations and examine introductory and important ideas in each, usually through the lens of important problems that involve differential equations. Written at a sophomore level, the text is accessible to students who have completed multivariable calculus. With a systems-first approach, the book is appropriate for courses for majors in mathematics, science, and engineering that study systems of differential equations.
Because of its emphasis on linearity, the text opens with a full chapter devoted to essential ideas in linear algebra. Motivated by future problems in systems of differential equations, the chapter on linear algebra introduces such key ideas as systems of algebraic equations, linear combinations, the eigenvalue problem, and bases and dimension of vector spaces. This chapter enables students to quickly learn enough linear algebra to appreciate the structure of solutions to linear differential equations and systems thereof in subsequent study and to apply these ideas regularly.
The book offers an example-driven approach, beginning each chapter with one or two motivating problems that are applied in nature. The following chapter develops the mathematics necessary to solve these problems and explores related topics further. Even in more theoretical developments, we use an example-first style to build intuition and understanding before stating or proving general results. Over 100 figures provide visual demonstration of key ideas; the use of the computer algebra system Maple and Microsoft Excel are presented in detail throughout to provide further perspective and support students' use of technology in solving problems. Each chapter closes with several substantial projects for further study, many of which are based in applications.
Errata sheet available at: www.oup.com/us/companion.websites/9780195385861/pdf/errata.pdf

This volume consists of written chapters taken from the presentations at the symposium "100+ Years of Plastics: Leo Baekeland and Beyond," held March 22, 2010, at the 239th ACS National Meeting in San Francisco. The symposium celebrates the 100th anniversary of the formation of General Bakelite Corp., which was preceded by Leo Baekland's synthesis of Bakelite in 1907 and the unveiling of the Bakelite process in 1909. It is quite reasonable to use the synthesis of Bakelite as the starting point of the Age of Plastics. Indeed, Time magazine in its June 14, 1999, issue on the 100 most influential people of the 20th century chose Leo Baekeland and his Bakelite synthesis as the sole representative of chemistry.
Leo Baekeland and Bakelite are the topics of the first four chapters of this volume. The first two chapters come from the perspective of Baekeland family members. Carl Kaufmann is related to the Baekeland family through marriage and is the author of the only full-length biography of Baekeland, published as a master's thesis from the University of Delaware. As a family member Kaufmann had access to all of Baekeland's papers. This first chapter (Leo H. Baekeland) is not only a biographical sketch, but an exploration of Baekeland's effect on the chemical industry. Hugh Karraker is Baekeland's great-grandson, and his chapter (A Portrait of Leo H. Baekeland) provides a family picture of the great inventor. Gary Patterson's chapter (Materia Polymerica: Bakelite) goes into the history of Bakelite chemistry, while Burkhard Wagner's contribution (Leo Baekeland's Legacy-100 Years of Plastics) covers the history of Bakelite manufacture through time and space, finishing with a description of another Baekeland legacy, the Baekeland Award given through the North Jersey Section of the ACS.
In later chapters, Les Sperling (History of Interpenetrating Polymer Networks Starting with Bakelite-Based Compositions) covers the improvements in interpenetrating networks. James Economy and Z. Parkar (Historical Perspectives on Phenolic Resins and High-Temperature Aromatic Polyesters of p-Hydroxybenzoic Acid and Their Copolyesters) follow the paths of resoles, novolaks, and related chemicals.

The role of the Maillard reaction in forming flavors from amino acid and sugar precursors has been studied for many years. To establish the basic chemistry of the reaction, researchers have used model systems, often solutions of a single amino acid with a single sugar. Despite the apparent simplicity of the system, heating such a solution can generate tens if not hundreds of compounds, which requires careful and time-consuming analysis to identify and quantify each component.
Data from the model systems has allowed researchers to study the pathways that lead to flavor formation, and various schemes have been proposed to identify the main "routes" that lead to flavor compounds. Such schemes have led to one of the main control principles, namely an understanding of the role of amino acids in forming some characteristic aromas, e.g., bread flavor from proline, as well as an appreciation of the role of C5 and C6 sugars in controlling the rate of reaction.
Recently, the formation of taste compounds through the Maillard reaction has been investigated and new potent compounds have been discovered that can contribute to the overall flavor formed during the Maillard reaction. These findings also offer the potential for control and manipulation of the Maillard reaction to form specific types of flavor. Although the nature of the end-products of the Maillard reaction in both food and model systems are well documented, applying these principles to control flavor formation in real foods has proved difficult.
This book describes recent research and developments related to the control of the Maillard reaction to give optimum flavor quality. These include kinetic modeling of the reaction, the effect of physical parameters (temperature, time, moisture content, pH), and the effect of chemical parameters (amino acid and sugar composition, the presence of other components). The topics covered relate to real food systems and reaction product flavorings, as well as model systems. Contributors from academia and industry have come together to provide an up to date overview of progress in this important area of flavor research.

This third volume of NMR Spectroscopy in the Undergraduate Curriculum continues the work we started with the first and second volumes in providing effective approaches for using nuclear magnetic resonance spectrometers as powerful tools for investigating a wide variety of phenomena at the undergraduate level. This volume focuses on upper-level courses and NMR spectroscopy across the curriculum. The applications and strategies in this volume will be helpful to those who are looking to transform their curriculum by integrating more NMR spectroscopy, to those who might not have considered NMR spectroscopy as a tool for solving certain types of problems, or for those seeking funding for a new or replacement NMR spectrometer.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

A combination of population growth, public health failures, environmental degradation and rapid global transportation has resulted in a world that is at increasing risk to vectorborne and other infectious diseases. A large percentage of emerging diseases are vectorborne and over one-third of the agents on the list of greatest concern from bioterrorism are vectorborne. Many of these diseases are viral that have no effective drug or vaccine treatments. Drug and insecticide resistance is now common and has greatly compromised our ability to provide effective and affordable control. Parasitic diseases, including malaria, leishmmaniasis and African trypanosomiasis are likewise increasing in many parts of the world. Control programs for onchocerciasis and to some extent filariasis are reducing the impact of these diseases, largely due to the availability of filaricides such as ivermectin. Chagas disease has also declined significantly through home improvements and indoor insecticide application against the domicilary kissing bug vectors.
Despite these gains, this tend has not been sustainable. Instead, infectious disease is now responsible for greater than 25% of all deaths and nearly 50% of premature deaths among those under 45 years of age, and 63% for children less than 4 years of age. A significant proportion of these deaths is attributed to vectorborne diseases, particularly from malaria ( 11%). Indeed, more that 1 million people are killed annually by malaria, about 3000 per day. It is estimated that 700,000 children under the age of 5 die of malaria and at least 300 million are ill due to malaria each year. In response, the American Institute of Medicine (2003) has called for a renewed effort to rebuild public health infrastructures needed to conduct disease surveillance and vector control programs and to increase research to provide improved pesticides and their use, new repellents, new biopestcides and biocontrol agents to augment pesticidal control, as well as novel strategies to interrupt pathogen transmission.
With these goals in mind, we convened the first vector control symposium as part of the scientific program of the 3rd Pan-Pacific Conference of Pesticide Science in 2003. Five years after (2008), we re-convened this expanded topic at the 4th Pan-Pacific Conference on Pesticide Science and the scientific presentations made over two days comprise this current volume, Advances in Human Vector Control. The book covers two major areas: 1) Current Status and Control Practices, covering malaria, dengue, Chagas, human lice, cockroach and house dust mite issues; and 2) Novel Approaches and Resistance Management of these diseases. Chapters are provided by internationally-recognized experts who are actively involved in vector control and management, providing an up to date summary of this critically important area of public health. The effective use of novel control strategies is stressed and the status of recently acquired genomic approaches is critically reviewed.

This volume is an attempt to educate, to provide a source of information, knowledge, and wisdom to the person who has spent so much time and energy on his or her schooling. The Council for Chemical Research (CCR) and the American Chemical Society (ACS) have both spent considerable effort over the past decades focusing on how to ensure that graduate education in the chemical sciences remains at the absolute highest caliber, and produces the best possible professionals. In spite of notable efforts from both organizations to prepare graduate students for the professional world, neither has specifically asked what a person needs to be successful once they have both the Ph.D. and the first job in hand. Put succinctly, there is much more to being successful in a career in chemistry than just the hard-earned Ph.D. degree. What You Need for the First Job, Besides the Ph.D. in Chemistry is based on a symposium of the same name held at the 246th National Meeting of the American Chemical Society, which took place in Indianapolis, Indiana in September, 2013. This book is the result of seeds that were planted during numerous informal conversations at the annual meetings of the CCR, as well as during such discussions at national and regional meetings of the ACS, and at the ACS employment clearing houses. The authors felt that the same intense focus a person needs to earn a Ph.D. might actually work against the attention to other details needed in order to be successful once he or she has obtained a position. Leaders want to ensure that new hires are working effectively toward tenure, are quickly becoming productive members of their corporate team, or are well integrated into their government laboratory research group. While it is easy to lump factors other than technical competence in one's job under the term "soft skills," this is an oversimplification. This book represents an attempt to have voices from all three pillars of the chemical enterprise - academia, industry, and government laboratories - heard in terms of relating what is important for their newly hired Ph.D.-holders. What You Need for the First Job, Besides the Ph.D. in Chemistry will be a valuable resource for first-time job seekers, as well as those with aspirations of a future career in the chemical sciences.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

Viruses that infect plants are responsible for reduction in both yield and quality of crops around the world, and thus are of great economic importance. This has provided the impetus for the extensive research into the molecular and cellular biology of these pathogens and into their interaction with their plant hosts and their vectors. However, interest in plant viruses extends beyond their ability to damage crops. Many plant viruses - for example, tobacco mosaic virus - have been used as model systems to provide basic understanding of how viruses express genes and replicate. Others permitted the elucidation of the processes underlying RNA silencing, now recognized as a core epigenetic mechanism underpinning numerous areas of biology. This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. The book concludes with two chapters on biotechnological applications of plant viruses. Throughout, the focus is on the most recent, cutting-edge research, making this book essential reading for everyone working with plant viruses.

Through four editions, Lactic Acid Bacteria: Microbiological and Functional Aspects, has provided readers with information on the how's and why's lactic acid-producing fermentation improves the storability, palatability, and nutritive value of perishable foods. Thoroughly updated and fully revised, with 12 new chapters, the Fifth Edition covers regulatory aspects globally, new findings on health effects, properties and stability of LAB as well as production of target specific LAB. The new edition also addresses the technological use of LAB in various fermentations of food, feed and beverage, and their safety considerations. It features the detailed description of the main genera of LAB as well as such novel bacteria as fructophilic LAB and novel probiotics and discusses such new targets as cognitive function, metabolic health, respiratory health and probiotics. Key Features: In 12 new chapters, findings are presented on health effects, properties and stability of LAB as well as production of target specific LAB Covers such novel bacteria as fructophilic LAB and novel probiotics Presents new discoveries related to the mechanisms of lactic acid bacterial metabolism and function Covers the benefits of LAB, both in fermentation of dairy, cereal, meat, vegetable and silage, and their health benefits on humans and animals Discusses the less-known role of LAB as food spoilers Covers the global regulatory framework related to safety and efficacy