In recent decades immunology has been one of the most exciting--and
successful--fields of biomedical research. Over the past thirty
years immunologists have acquired a detailed understanding of the
immune system's unique recognition mechanism and of the cellular
and chemical means used to destroy or neutralize invading
organisms. This understanding has been formulated in terms of the
clonal selection theory, the dominant explanation of immune
behavior. That story is the subject of "The Generation of
Diversity,"
A major problem for immunologists had long been to determine how
cells of the immune system could produce millions of distinct
antibodies--and produce them on demand. The clonal selection theory
explains that cells with genetic instructions to produce each
antibody exist in the body in small numbers until exposure to the
right molecule--the antigen--triggers the selective cloning that
will reproduce exactly the cell needed. But how can so many
different antibody-producing cells be generated from such limited
genetic material? The solution to this question came from new
applications of molecular biology, and, as the authors argue, the
impact of the new techniques changed both the methods and the
concepts of immunology.
"The Generation of Diversity" is an intellectual history of the
major theoretical problem in immunology and its resolution in the
post-World War II period. It will provide for immunologists
essential background for understanding the conceptual conflicts
occurring in the field today.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!