Books > Medicine > Clinical & internal medicine > Haematology
|
Buy Now
Immunology and Blood Transfusion - Proceedings of the Seventeenth International Symposium on Blood Transfusion, Groningen 1992, organized by the Red Cross Blood Bank Groningen-Drenthe (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R2,970
Discovery Miles 29 700
|
|
Immunology and Blood Transfusion - Proceedings of the Seventeenth International Symposium on Blood Transfusion, Groningen 1992, organized by the Red Cross Blood Bank Groningen-Drenthe (Paperback, Softcover reprint of the original 1st ed. 1993)
Series: Developments in Hematology and Immunology, 28
Expected to ship within 10 - 15 working days
|
In transfusion medicine the scientific fundamentals of immunology
have had a considerable clinical impact. Transfusion may suppress
the immunity but some patients could suffer disadvantages including
GvHD, alloimmunisation and possible cancer, where white cells (WBC)
play pivotal roles in this phenomenon, presenting antigens and
producing cytokines. A clinical application of this practice is
LAK-cells targeted against cancer. MHC on the WBC may provide
additional immunological modulations through series of secondary
messengers. Thus reduction of WBC in the blood and bone marrow may
be advantageous for patients. On the other hand, sharing a part of
MHC or making the transplanted white cells anergic by storage may
be even more advantageous for patients. CMV infection could mimic
part of this MHC. UV radiation is effective in the inactivation of
the WBC although filters are easy means for such removal. However,
their accurate quantification requires flow cytometry that has
considerable potential application in blood transfusions. Idiotypic
antibody could play an important role in platelet theory. However,
the potential infection risks in transfusion like HIV and HCV
remain, but application of molecular biological methods like PCR or
RT/PCR has great potentials in detection of infectious diseases,
transplantation and genetic disorders. Immuno affinity purified
concentrates, like factor IX and protein C, could reduce patients'
immune functions, where in the future protein C could be derived
from transgenic animals. Advances are sure to emerge through
adoptive immunotherapy and gene therapies are exciting prospects
when genes transferred into lymphocytes could be used to correct
cell mediated immune deficiency, as in ADA.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.