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Targets of Cancer Diagnosis and Treatment - Ion Transport in Tumor Biology (Hardcover, 1st ed. 2022)
Loot Price: R4,209
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Targets of Cancer Diagnosis and Treatment - Ion Transport in Tumor Biology (Hardcover, 1st ed. 2022)
Series: Reviews of Physiology, Biochemistry and Pharmacology, 183
Expected to ship within 12 - 17 working days
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This third and final volume in the "Ion Transport in Tumor Biology"
collection presents novel diagnostic and therapeutic approaches in
cancer based on the exploitation of ion transport proteins. The
authors critically examine several transportome members,
particularly Na+, K+, Ca2+, and Cl- channels, as well as organic
solute carriers regarding their suitability as therapeutic targets.
Synergistic effects resulting from the combined use of classical
cytostatics with ion transport-inhibiting drugs are pointed out,
and the capability of bispecific antibodies to function as
anticancer drugs is discussed. As readers will also learn, the use
of ion channel inhibitors could improve the outcome of radiotherapy
because the development of radio-resistance during radiotherapeutic
treatment often correlates with increases in the expression levels
and conductance of ion channels. The translational topics of this
volume form a bridge between biochemical research and therapeutic
application. As part of a three-volume collection, this book will
fascinate members of the active research community, as well as
clinicians in the cancer field.
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