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Transportome Malfunction in the Cancer Spectrum - Ion Transport in Tumor Biology (Paperback, 1st ed. 2021)
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Transportome Malfunction in the Cancer Spectrum - Ion Transport in Tumor Biology (Paperback, 1st ed. 2021)
Series: Reviews of Physiology, Biochemistry and Pharmacology, 181
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This is the first of three volumes in the "Ion Channels &
Transporters in Tumor Biology" collection, which discusses the
function of ion transport proteins in cellular and systemic
homeostasis. The authors highlight the role of the so-called
transportome, which is defined by the entirety of ion transporters
and ion channels. Thereby, readers will get a better understanding
of the impact dysregulated ion transport has on the whole spectrum
of cancer types. Cancers display deficiencies in several, sometimes
interdependent members of the transportome. Clinicians will be
interested in the fact that controlled expression of ion transport
proteins dramatically impacts the life span of cancer patients, as
shown in recent studies. These observations offer a promising
outlook for biomedical scientists, as members of the transportome
could be the tumor markers of tomorrow - both for diagnostic and
therapeutic purposes. As part of a three-volume collection, this
book will fascinate members of the active research community, as
well as clinicians from the cancer field.
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