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Bioreactor Systems for Tissue Engineering (Paperback, Softcover reprint of hardcover 1st ed. 2009)
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Bioreactor Systems for Tissue Engineering (Paperback, Softcover reprint of hardcover 1st ed. 2009)
Series: Advances in Biochemical Engineering/Biotechnology, 112
Expected to ship within 10 - 15 working days
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The editors of this special volume would first like to thank all
authors for their excellent contributions. We would also like to
thank Prof. Dr. Thomas Scheper, Dr. Marion Hertel and Ulrike
Kreusel for providing the opportunity to compose this volume and
Springer for organizational and technical support. Tissue
engineering represents one of the major emerging fields in modern
b- technology; it combines different subjects ranging from
biological and material sciences to engineering and clinical
disciplines. The aim of tissue engineering is the development of
therapeutic approaches to substitute diseased organs or tissues or
improve their function. Therefore, three dimensional biocompatible
materials are seeded with cells and cultivated in suitable systems
to generate functional tissues. Many different aspects play a role
in the formation of 3D tissue structures. In the first place the
source of the used cells is of the utmost importance. To prevent
tissue rejection or immune response, preferentially autologous
cells are now used. In particular, stem cells from different
sources are gaining exceptional importance as they can be
differentiated into different tissues by using special media and
supplements. In the field of biomaterials, numerous scaffold
materials already exist but new composites are also being developed
based on polymeric, natural or xenogenic sources. Moreover, a very
important issue in tissue en- neering is the formation of tissues
under well defined, controlled and reprod- ible conditions.
Therefore, a substantial number of new bioreactors have been
developed.
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