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Stress Proteins (Paperback, Softcover reprint of the original 1st ed. 1999)
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Stress Proteins (Paperback, Softcover reprint of the original 1st ed. 1999)
Series: Handbook of Experimental Pharmacology, 136
Expected to ship within 10 - 15 working days
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This work is concerned with a group of proteins which were
originally consid ered to be an esoteric phenomenon but which have
now been shown to play critical roles both in normal and stressed
cells as well as being involved in a variety of human diseases. It
is the purpose of this work to give a comprehen sive view of these
proteins and their various aspects. After an introductory chapter
providing an overview of these proteins, the work is divided into
four main sections each of which deals with one important aspect of
these proteins. Thus, the first section contains a series of
chapters which describe individual stress proteins and their roles
in particular biological phenomena. Evidently, the induction of
these proteins by elevated tempera ture or other stresses is their
defining feature and the second section of this book therefore
considers the regulation of stress protein gene expression both by
stressful stimuli such as elevated temperature or ischaemia and by
non stressful stimuli such as cytokines.
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