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Quasispecies: From Theory to Experimental Systems (Hardcover, 1st ed. 2016)
Loot Price: R4,847
Discovery Miles 48 470
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Quasispecies: From Theory to Experimental Systems (Hardcover, 1st ed. 2016)
Series: Current Topics in Microbiology and Immunology, 392
Expected to ship within 12 - 17 working days
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This volume brings together recent developments in quasispecies
theory extended to variable environments and practical applications
in elucidating viral dynamics and treatment designs. In particular,
the existence of an error threshold in rugged fitness landscapes
has opened the way to a new antiviral strategy termed lethal
mutagenesis, which is now under intensive theoretical, experimental
and clinical investigation. As such the book explains how an
understanding of quasispecies dynamics within infected organisms
has increased our knowledge of viral disease events. From a
clinical perspective, population dynamics highlights important
problems for viral disease control, such as the selection of
drug-resistant mutants that often accompanies treatment failures,
and suggests means of increasing the effectiveness of antiviral
treatments. The book is intended for students and scientists
interested in basic and applied aspects of biophysics, chemistry,
biology, evolution and medical virology.
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