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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Ventricular/Vascular Coupling - Clinical, Physiological, and Engineering Aspects (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R2,686
Discovery Miles 26 860
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Ventricular/Vascular Coupling - Clinical, Physiological, and Engineering Aspects (Paperback, Softcover reprint of the original 1st ed. 1987)
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Physiologists have long been interested in the interaction, or
coupling, between the heart and the vasculature. The early
literature consists mainly of phenomenological descriptions of
cardiac alterations resulting from specific interventions in the
vasculature. Hundreds of studies, for example, describe functional
aspects of hypertrophied myocardium associated with the excessive
vascular loading produced by various types of experimental
hypertension. Recently, the concepts of ventricular/vascular
interaction have found important clinical application. The
widespread use of vaso dilators and of intraaortic counterpUlsation
balloons for unloading an ov erburdened, diseased heart is a prime
example. Despite the interest in this field, until as recently as
20 years ago we were not able to describe ventricular or vascular
function in a framework suitable for quantitatively expressing the
interaction between these two complex systems. Three major
developments-description of ventricular function in terms of both
the time-varying elastance and the pump function graph and
quantification of vascular function in terms of impedance have
changed this. These functional descriptions now enable systems en
gineers, bioengineers, physiologists, and clinicians to address
very specific quantitative aspects of ventricular/vascular
interaction and have resulted in a flurry of papers and symposia
devoted to this subject."
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