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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes
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Exploring Pancreatic Metabolism and Malignancy (Paperback, 1st ed. 2019)
Loot Price: R2,957
Discovery Miles 29 570
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Exploring Pancreatic Metabolism and Malignancy (Paperback, 1st ed. 2019)
Expected to ship within 10 - 15 working days
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This book comprehensively describes the association between
metabolic syndrome and pancreatic cancer progression, and the
mechanism of action and target definition with a view to drug
discovery. Metabolic syndrome, which includes adnominal obesity,
hypertension, dyslipidemia, and hyperglycemia, has recently been
shown to play an important role in the etiology and progression of
various cancers. Further, obesity and diabetes have been associated
with an increased incidence of gastric cancers. The book reviews
the key biological mechanisms underlying the association between
metabolic dysregulation, including obesity-associated enhancement
of growth factor signaling, inflammation, and perturbation in
pancreatic cancer cell growth and metastasis. It also illustrates
the role of the inflammatory signaling pathway in metabolic
diseases as well as tumor growth and explores the potential of
these pathways as the rational targets for pancreatic cancer
therapy. Lastly, the book offers a comprehensive description of the
challenges associated with diabetes and pancreatic cancer therapy.
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