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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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5-HT2C Receptors in the Pathophysiology of CNS Disease (Hardcover, 2011 Ed.)
Loot Price: R5,538
Discovery Miles 55 380
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5-HT2C Receptors in the Pathophysiology of CNS Disease (Hardcover, 2011 Ed.)
Series: The Receptors, 22
Expected to ship within 10 - 15 working days
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Research of 5-HT2c receptors stretches back twenty-five years, and
while much of it has been productive, the past decade of research
has been extraordinary in terms of both amount produced and
insights gained. It is hardly surprising that 5-HT2c receptor
research has grown so fruitful, given that it is a prominent
central serotonin receptor subtype widely expressed within the
central and the peripheral nervous system and is thought to play a
major role in the regulation of numerous behaviors. It has further
been shown by experimental and clinical observation that it may
represent a possible therapeutic target for the development of
drugs for a range of central nervous system disorders. The time,
therefore, is more than appropriate to offer the first ever
overview of the research of 5-HT2c receptors. Part of the popular
and important series, "The Receptors," The 5-HT2c Receptor provides
a thorough update of the functional status of the 5-HT2c receptor.
It covers the molecular, cellular, anatomical, biochemical and
behavioral aspects of this receptor so as to highlight its
distinctive regulatory properties and the emerging functional
significance of constitutive activity and RNA-editing in vivo. In
addition, the book investigates the receptors' therapeutic
potential in a range of different diseases, treated individually in
separate chapters, including depression, drug abuse, schizophrenia,
eating disorders, Parkinson's disease, Prader-Willi Syndrome,
Alzheimer's disease and epilepsy. While not exhaustive, this text
is a vital tool in understanding the past and inspiring the future
of interdisciplinary research on the 5-HT2c receptor.
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