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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Apoptosis and Inflammation (Hardcover, 1999 ed.)
Loot Price: R5,607
Discovery Miles 56 070
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Apoptosis and Inflammation (Hardcover, 1999 ed.)
Series: Progress in Inflammation Research
Expected to ship within 10 - 15 working days
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Apoptosis is a form of cell death that occurs in a controlled
manner and is generally noninflammatory in nature. Apoptosis, or
programmed cell death, implies a cell death that is part of a
normal physiological process of pruning of unneeded cells. However,
many disease conditions utilize apoptosis for pathological ends,
resulting in inappropriate cell death and tissue destruction. This
book starts with an introduction that reviews the general
characteristics of apoptosis, its regulation and its role in
physiology and disease. Next, the book focuses on three areas as
they relate to inflammatory cells and diseases. The first area
consists of chapters on signals for apoptosis important to
inflammatory cells, namely growth factors and arachidonic acid
metabolism. The next area that the book focuses on are effects at
the cellular level, on cell survival versus cell death and signals
critical for cell function in both normal and disease states. These
topics are covered in chapters on lymphocytes, granulocytes,
chondrocytes and keratinocytes. The last area that the book focuses
on are events at the level of tissue and disease, looking at the
evidence for altered apoptosis and/or apoptotic processes in immune
and inflammatory diseases. These topics are covered in chapters on
rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal
disease. Together, these chapters will provide the reader with the
latest insight in the role of apoptosis in inflammatory cells and
diseases. This book starts with an introduction that reviews the
general characteristics of apoptosis, its regulation and its role
in physiology and disease. Next, the book focuses on three areas as
they relate to inflammatory cells and diseases. The first area
consists of chapters on signals for apoptosis important to
inflammatory cells, namely growth factors and arachidonic acid
metabolism. The next area that the book focuses on are effects at
the cellular level, on cell survival versus cell death and signals
critical for cell function in both normal and disease states. These
topics are covered in chapters on lymphocytes, granulocytes,
chondrocytes and keratinocytes. The last area that the book focuses
on are events at the level of tissue and disease, looking at the
evidence for altered apoptosis and/or apoptotic processes in immune
and inflammatory diseases. These topics are covered in chapters on
rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal
disease. Together, these chapters will provide the reader with the
latest insight in the role of apoptosis in inflammatory cells and
diseases.
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