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Biomaterials as Stem Cell Niche (Hardcover, 2011 ed.)
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Biomaterials as Stem Cell Niche (Hardcover, 2011 ed.)
Series: Studies in Mechanobiology, Tissue Engineering and Biomaterials, 2
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Recent developments in stem cell biology have opened new directions
in cell therapy. This book provides the state-of-the-art
developments in using biomaterials as artificial niches for
engineering stem cells, both for the purpose of better
understanding their biology under 3D biomimetic conditions as well
as for developing new strategies for efficient long term
maintenance and directed differentiation of stem cells into various
therapeutic lineages. Animal and human stem cells of both embryonic
and adult origin are discussed with applications ranging from nerve
regeneration, orthopedics, cardiovascular therapy, blood cell
generation and cancer therapy. Both synthetic and natural
biomaterials are reviewed with emphasis on how material-stem cell
interactions direct specific signaling pathways and ultimately
modulate the cell fate. This book is valuable for biomaterial
scientists, tissue engineers, clinicians as well as stem cell
biologists involved in basic research and applications of adult and
embryonic stem cells.
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