X-Ray Phase-Contrast Tomography - Underlying Physics and Developments for Breast Imaging (Hardcover, 1st ed. 2020)

X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Springer Theses
Release date:	November 2020
First published:	2020
Authors:	Luca Brombal
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	140
Edition:	1st ed. 2020
ISBN-13:	978-3-03-060432-5
Categories:	Books > Science & Mathematics > Physics > Atomic & molecular physics Books > Medicine > Other branches of medicine > Medical imaging > Radiology Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	3-03-060432-2
Barcode:	9783030604325

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