In the past two decades, great progress has been made in the
understanding of copper as a bioelement. The book summarizes the
current knowledge of copper toxicity, homeostasis and resistance in
bacteria, in which proteins like copper ATPases, copper chaperones
and copper-responsive regulators of gene expression play major
roles. The author also discusses the metallation of cuproenzymes.
The evolution of the use of copper by cells and of
copper-homeostatic proteins are is also considered in this Brief.
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