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Vasculopathies - Behavioral, Chemical, Environmental, and Genetic Factors (Hardcover, 1st ed. 2018)
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Vasculopathies - Behavioral, Chemical, Environmental, and Genetic Factors (Hardcover, 1st ed. 2018)
Series: Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems, 8
Expected to ship within 10 - 15 working days
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This volume presents one of the clinical foundations of
vasculopathies: the biological markers and risk factors associated
with cardiovascular disease. A detailed biological and clinical
framework is provided as a prerequisite for adequate modeling.
Chapter 1 presents cardiovascular risk factors and markers, where
the search for new criteria is aimed at improving early detection
of chronic diseases. The subsequent chapters focus on hypertension,
which involves the kidney among other organs as well as many
agents, hyperglycemia and diabetes, hyperlipidemias and obesity,
and behavior. The last of these risk factors includes altered
circadian rhythm, tobacco and alcohol consumption, physical
inactivity, and diet. The volumes in this series present all of the
data needed at various length scales for a multidisciplinary
approach to modeling and simulation of flows in the cardiovascular
and ventilatory systems, especially multiscale modeling and coupled
simulations. The cardiovascular and respiratory systems are tightly
coupled, as their primary function is to supply oxygen to and
remove carbon dioxide from the body's cells. Because physiological
conduits have deformable and reactive walls, macroscopic flow
behavior and prediction must be coupled to nano- and microscopic
events in a corrector scheme of regulated mechanisms. Therefore,
investigation of flows of blood and air in anatomical conduits
requires an understanding of the biology, chemistry, and physics of
these systems together with the mathematical tools to describe
their functioning in quantitative terms.
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