Endogenous Stem Cell-Based Brain Remodeling in Mammals (Hardcover, 2014 ed.)

This text highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury. The second part is devoted to the endogenous reparative potential of the brain, including its limitations, and articles focusing on defined pathologies (e.g. anoxia/hypoxia, epilepsy, traumatic brain injury and stress) in animal models and in humans pinpoint eventual ways these pathologies might be manipulated. The third and final focuses on the "dark side" of stem cells for brain repair or of the manipulation of spontaneous adaptive events after injury (e.g. genomic instability, sensitization to cancerous transformation and defective neural networks).

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Stem Cell Biology and Regenerative Medicine
Release date:	February 2014
First published:	2014
Editors:	Marie-Pierre Junier • Steven G. Kernie
Dimensions:	235 x 155 x 14mm (L x W x T)
Format:	Hardcover
Pages:	230
Edition:	2014 ed.
ISBN-13:	978-1-4899-7398-6
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General
LSN:	1-4899-7398-2
Barcode:	9781489973986

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