Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Gold and its Complexes in Anticancer Chemotherapy (Hardcover, 1st ed. 2021)
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Gold and its Complexes in Anticancer Chemotherapy (Hardcover, 1st ed. 2021)
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This book presents an overview of cancer and the genesis, and
development of different treatment strategies and modalities
against cancer. The emergence of gold and its complexes as
promising anticancer chemotherapeutic agents have the potential to
substitute or replace the platinum based chemotherapeutic agents.
Gold complexes have demonstrated considerable anti-proliferative
properties, chiefly attributed to their anti-mitochondrial effects,
they make gold complexes excellent candidates as anti-cancer agents
compared to their platinum-based counterparts. This book provides a
critical review of recent advances made in the development of gold
complexes as anti-cancer agents. In this context, it examines a
number of different ligand architectures, provides comprehensive
information on gold complexes' mechanism of action and toxicity
issues and, in closing, outlines future research directions.
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