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Oncogenes as Transcriptional Regulators, v. 1 - Retrovial Oncogenes (Hardcover, illustrated edition)
Loot Price: R2,397
Discovery Miles 23 970
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Oncogenes as Transcriptional Regulators, v. 1 - Retrovial Oncogenes (Hardcover, illustrated edition)
Series: Progress in Gene Expression S.
Expected to ship within 12 - 17 working days
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The study of the molecular events leading to cellular
transformation and cancer has progressed significantly in the last
decade, and it has become apparent that many genes subject to
modification in cancer are, in fact, transcription factors that
govern the execution of the genetic programme of the cell.
Transcription factors can behave either as oncogenes or as tumour
suppressor genes. To date only a limited number of transcription
factors have been associated with cancer. This volume deals with
several transcription factor families that were first identified in
oncogenic retroviruses. Each chapter contains a description of the
structure of the transcription factors, the nature of target genes,
the regulation of their activities, and an explaination of how they
can deregulate cell growth and differentiation. This text should be
suitable for the specialist scientist and the advanced student
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