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Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
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Rapid Cell Magnetisation Using Cationised Magnetoferritin (Hardcover, 1st ed. 2017)
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Rapid Cell Magnetisation Using Cationised Magnetoferritin (Hardcover, 1st ed. 2017)
Series: Springer Theses
Expected to ship within 12 - 17 working days
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Bringing together nanoscience with stem cell and bacterial cell
biology, this thesis is truly interdisciplinary in scope. It shows
that the creation of superparamagnetic nanoparticles inside a
protein coat, followed by chemical functionalisation of the protein
surface, provides a novel methodology for cell magnetisation using
incubation times as short as one minute. Crucially, stem cell
proliferation and multi-lineage differentiation capacity is not
impaired after labelling. Due to the unspecific labelling
mechanism, this thesis also shows that the same magnetic protein
nanoparticles can be used for rapid bacterial magnetisation. Thus,
it is possible to magnetically capture and concentrate pathogens
from clinical samples quickly and highly efficiently.
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