Radiosensitizers and Radiochemotherapy in the Treatment of Cancer (Hardcover)

Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals. At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy. In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.

General

Imprint:	Crc Press
Country of origin:	United States
Series:	Series in Medical Physics and Biomedical Engineering
Release date:	December 2014
First published:	2014
Authors:	Shirley Lehnert
Dimensions:	234 x 156 x 34mm (L x W x T)
Format:	Hardcover
Pages:	548
ISBN-13:	978-1-4398-2902-8
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Other branches of medicine > Medical imaging > Radiology Books > Science & Mathematics > Physics > Applied physics & special topics > Medical physics Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4398-2902-0
Barcode:	9781439829028

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