Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Radiosensitizers and Radiochemotherapy in the Treatment of Cancer (Hardcover)
Loot Price: R5,369
Discovery Miles 53 690
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Radiosensitizers and Radiochemotherapy in the Treatment of Cancer (Hardcover)
Series: Series in Medical Physics and Biomedical Engineering
Expected to ship within 12 - 17 working days
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Total price: R5,389
Discovery Miles: 53 890
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Radiosensitizers and Radiochemotherapy in the Treatment of Cancer
catalogs and describes the mechanism of action for entities
characterized as radiosensitizers. Developments in the biological
and physical sciences have introduced new radiosensitizers and
defined novel targets for radiosensitization. As a result, a book
about radiosensitization must now address a huge range of topics,
covering everything from molecular oxygen and high Z elements to
monoclonal antibodies and complex phytochemicals. At the molecular
level, the understanding of the molecular consequences of DNA
damage and the DNA damage response have informed the development of
targeted radiosensitizers and shed light on the mode of action of
radiochemotherapy protocols of known clinical efficacy. In this
book the mechanisms of action at the molecular and cellular level
are described for documented radiosensitizers including, where
applicable, a brief history of their clinical use and most recent
clinical results. In addition, the clinical context is addressed
including the importance of factors such as dose and dose rate,
normal tissue toxicity, and drug delivery. Intuitively organized by
topic and application, the book includes extensive illustrations,
end-of-chapter summaries, and a wealth of references.
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