Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C H Bonds (Hardcover, 1st ed. 2016)

This thesis reports the latest developments in the direct amination of various C H bonds using an H Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines. The material outlined in this book shows how McDonald achieved C H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source. McDonald's findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Springer Theses
Release date:	August 2016
First published:	2016
Authors:	Stacey L. Mcdonald
Dimensions:	235 x 155 x 11mm (L x W x T)
Format:	Hardcover
Pages:	144
Edition:	1st ed. 2016
ISBN-13:	978-3-319-38877-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Chemistry > Organic chemistry > Organometallic chemistry Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > General
LSN:	3-319-38877-0
Barcode:	9783319388779

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