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Measles Virus (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R2,764
Discovery Miles 27 640
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Measles Virus (Paperback, Softcover reprint of the original 1st ed. 1995)
Series: Current Topics in Microbiology and Immunology, 191
Expected to ship within 10 - 15 working days
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Measles, also called the greatest killer of children in history,
still annually affects about 50 million individuals and causes
close to a million deaths primarily in developing countries. Before
the advent of measles vaccine some 30 years ago, these figures were
roughly three times higher. Attenuated measles virus (MV) strains,
all quite closely related to the original Edmonston isolate, have a
very good record as a safe and highly efficacious vaccine and have
brought down the measles toll in industrialized countries to almost
negligible levels. However, recent outbreaks in the USA and Europe
have again brought the measles problem to public attention. Sadly
enough, these outbreaks were more instrumental in inducing
activities to drastically reduce and hopefully finally eradicate
measles than were the ten thousand times higher number of victims
in developing countries. To reach this goal, as detailed in this
volume, apparently it is not enough to of the existing vaccine as
was the rigorously enforce use case with smallpox eradication: the
intricacies of measles disease phenomena, in particular the
generalized immune suppression which favors secondary infections,
require more basic knowledge of the virus-host interactions and
probably the development of new vaccines for special applications
such as first immunizations of very young infants in developing
countries.
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