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Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes (Paperback, Softcover reprint of the original 1st ed. 1994)
Loot Price: R2,992
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Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes (Paperback, Softcover reprint of the original 1st ed. 1994)
Series: Frontiers of Virology, 3
Expected to ship within 10 - 15 working days
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Six members of the Herpesviridae family are human pathogens,
including herpes and 2 (HSV-I and 2), Epstein-Barr virus (EBV),
varicella zoster simplex virus I virus (VZV), human cytomegalovirus
(HCMV), and human herpesvirus 6 (HHV 6). Each of these viruses is
capable of causing distinct diseases of varying severity in
children, young adults, and the aged. The diseases range from
infection of epithelial tissue to the infection of internal organs
and white blood cells. A common feature of the six pathogenic human
herpesviruses is their ability to latently infect different cell
types in which the viral DNA is not integrated and is unable to
express its pathogenicity. Reactivation of the herpesviruses is a
result of cellular processes which reactivate viral genes, leading
to virus progeny and to signs of infection. Due to their ability to
become latent after initial infection, once the pathogenic
herpesviruses infect children they are maintained throughout life,
having the potential of cause various diseases upon reactivation.
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