The discovery of the spatial structure of the double-stranded
DNA molecule is one of the greatest achievements of science. It
would not be an exaggeration to say that the DNA double helix is a
distinguished symbol of modern biology.
Divided into three parts, DNA Liquid-Crystalline Dispersions and
Nanoconstructions covers the information presently available on the
condensation of various forms of DNA and describes practical
applications of the peculiar properties of the liquid-crystalline
particles.
- Part 1 describes the main methods used for condensation of
linear high- and low-molecular mass DNA, including their complexes
with polycations and circular DNA
- Part 2 compares the state and reactivity of double-stranded
nucleic acid molecules fixed spatially in the liquid-crystalline as
well as the same molecules under intracellular conditions
- Part 3 explains how the discovery of the fundamental principles
underlying the formation of nucleic acid liquid-crystalline
dispersion particles opens a gate for the operational use of these
principles in the area of nanotechnology and biosensorics
With detailed coverage of DNA liquid crystals, this book provides
an understanding of the information presently available on the
condensation of various forms of DNA. Double-stranded nucleic
acids, spatially organized in a liquid-crystalline structure,
represent an important polyfunctional tool for molecular biology
and nanobiotechnology. The possibility of programmed and controlled
variations in the properties of these molecules and in the
characteristics of their liquid-crystalline dispersions, provides
wide options for the formation of biologically active
three-dimensional structures with unique, widely applicable
properties.
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