The highs and heartbreak of caring for the animals we love You never know who or what is going to walk, crawl or slither through the doors of veterinary hospital... Clumsy Luna the Greyhound and her fragile front legs; the tortoise in need of a prosthetic leg; Jock the Saint Bernard and his problematic eyelashes; Edward the Burmese cat and his extravagant diet; the burly farmer and the world's tiniest Chihuahua, Lulu-bell... there is never a dull day in the life of a vet nurse. As the people who care for them around the clock, vet nurses are uniquely placed to speak for their patients and help us understand what our pets are going through. From emergency shifts at a posh London practice to a busy country hospital treating all manner of wildlife - snakes, foxes, hedgehogs - to working with equine-surgeons and teaching the art of care to new generations of vet nurses in New Zealand, Tales of a Vet Nurse is about a life devoted to saving our beloved and unconditional friends. Along the way, Jade enlightens readers to the forbidden feasts of Labradors, the dangers of x-raying prize-winning showjumpers, and the most common pets she sees as hospital inpatients.

Hematology data from "in vivo" toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials.

Covering the three main blood cell types - erythrocytes, leukocytes and thrombocytes, this work is designed to clarify topics for new entrants to the fields of laboratory animal hematology and toxicology, especially those topics where the rules for human hematology do not always apply. An entire chapter is devoted to immunotoxicology, a scientific discipline that is closely aligned with hematology.

The text also addresses pre-analytical and analytical variables that affect animal studies, as these play a far more important part when interpreting data in contrast to humans where many of these variables can be well controlled or have less physiological effect. Information has been collated from published papers, textbooks and unpublished data: Readers are provided withkey references to encourage further study

Diseases are a major threat to both wild and farmed fish. Pathogen-induced alterations in viability and growth of wild fish stocks can have implications on diversity and ecological status of aquatic ecosystems, as fish are main components of aquatic communities, and they can directly affect the exploitation of wild and farmed fish as a protein source for human consumption. Fish diseases can be a major factor influencing abundance and distribution of wild fish. Disease-related reduction of reproduction and/or age-specific survival can strongly affect wild stocks as it has been demonstrated for several species in distinct geographical locations. The book will be useful for fish farmers, managers, researchers and graduate students interested in fish diseases.

Since the publication of the original edition in 1982, pesticide-related poisonings, both single cases and epidemic-scale situations, have continued to occur unabated. This new edition of Pesticides and Neurological Diseases reviews current literature describing the effects of insecticides (chlorinated hydrocarbons, organophosphorus and carbamate esters, and the pyrethroid esters), fungicides (organomercurials, dithiocarbamates), and herbicides (chlorophenoxy acids and esters) on the mammalian nervous system. Acute and chronic exposures have resulted in both subtle and serious neurological deficits in the peripheral and central nervous systems, marked by transient effects preceding those of delayed onset and of persistent duration. The chapters have been largely revised and rewritten to introduce newer theories of mechanism(s) of action studied at the laboratory bench. New findings and observations on human intoxications are included as well.
This reference will interest physicians involved in environmental medicine and occupational health, as well as graduate students and researchers in the fields of neurophysiology, pharmacology, and the toxicology of pesticides. It may also be useful to the layperson interested in learning more about chemicals routinely used in the home, garden, greenhouse, orchards, and fields.

Sarcocystis is one of the most prevalent parasites of livestock and also infects many wild mammals, birds, and humans. Written by the authors who pioneered studies of Sarcocystosis of domestic animals, Sarcocystosis of Animals and Humans, Second Edition provides a current and comprehensive review of Sarcocystis and the infections it causes in animals and humans. The book reviews the history, structure, life cycle, pathogenesis, lesions, clinical signs, diagnosis, immunity, epidemiology, treatment, prevention, and control of Sarcocystosis. See What's New in the Second Edition: New section on molecular diagnosis and DNA characterization of Sarcocystis species New section on clinical sarcocystosis outbreaks in humans is added with a summary of all reports, symptoms, diagnosis, and treatment New section on acute fatal outbreaks of sarcocystosis in birds Complete description of the life cycles of all Sarcocystis species List of all species whose life cycles are known Comprehensive information on diagnosis, including molecular diagnosis Additional information on zoonoses In-depth coverage of treatment, control, and prevention Maintaining the format that made the first edition so popular, this new edition covers recent developments and excludes information that has become redundant. The authors include all literature and provide a comprehensive review of biology, clinical disease, economic losses, public health concerns, diagnosis, treatment, and prevention. They have tabulated information on all Sarcocystis species by host and listed species that should be considered species inquirende/invalid.

Shortlisted for the 2018 TWS Wildlife Publication Awards in the edited book category Decomposition and recycling of vertebrate remains have been understudied, hampered largely due to these processes being aesthetically challenging (e.g., smell and sight). Technological innovations have provided the means to explore new and historically understood natural systems to give us a plethora of new information. Carrion Ecology, Evolution, and Their Applications covers a broad spectrum of topics including the molecular mechanistic foundations that provide the basis for intra- and interspecific interactions related to population biology, community ecology, and how this manifests into habitat- and ecosystem-level importance. The book connects the science of carrion decomposition from genes to ecosystems in multidisciplinary synthesis of the science. This book brings together a team of global experts involved with measuring and understanding the process and effects of carrion ecology in nature, with special application in such applied fields as forensic entomology, habitat management, animal production (e.g., livestock and aquaculture), and human and environmental health. It fills a large literature gap in ecology, providing a synthesis and future directions important for studies of carrion decomposition that improve the general understanding of decomposition in ecosystems. The book fuses multiple disciplines into a single message explaining the importance of vertebrate carrion ecology in nature. Illustrates Carrion Decomposition in a 16-Page Color Insert with 40 Photos The authors illustrate how the study of carrion transcends the globe and expands systems of inquiry, broadening awareness of this important ecosystem process. Whether you are a student, academic, or professional, you will find this book insightful for the fields of molecular ecology, microbiology, entomology, forensics, population biology, community and ecosystem ecology, and human and environmental health.

Human Diseases from Wildlife presents information on the most prevalent and serious zoonotic diseases in the US and Canada, some of which have been national headline news like anthrax, influenza, and West Nile virus. Diseases that are caused by pathogens with the ability to infect both humans and animals are known as zoonotic diseases, which literally means "disease from animals." The issue of human-wildlife disease interactions is a growing concern as humans continue to interface with wildlife. People who handle wildlife including field workers, wildlife professionals, trappers, and hunters want to know about potential diseases, risks, and how to protect themselves from disease. This book was written because many people are uninformed about zoonotic diseases. This lack of information causes some people to have a heightened fear of zoonotic diseases, preventing them from enjoying wildlife or spending time outdoors. Other people needlessly expose themselves to disease by neglecting simple precautions. This book includes information on bacterial, spirochetal, rickettsial, and viral diseases as well as macroparasites and emerging zoonotic diseases. More than two dozen diseases are covered including rabies, tularemia, baylisascariasis, salmonellosis, leprosy, Lyme disease, Rocky Mountain spotted fever, and swimmer's itch. Each chapter contains the history of the disease, symptoms in humans, medical treatment, transmission of pathogens to humans, the role of wildlife as vectors, and methods to minimize risk. The diseases people can contract from wild animals can be both threatening and fascinating, and the book includes interesting information to make it more enjoyable to read.

Investigation of the complex issues surrounding the links between bovine tuberculosis and infected meat - with a contemporary resonance in the BSE scare. By the late 1890s, the question of bovine tuberculosis (TB) and infected meat had become one of national importance, reflecting a national sense of fear. Although the extent of the threat to health proved uncertain, bovine TB hadcome to stand at the centre of debates about diseased meat and public health. The anxiety it caused was part of a longer story, linked to concern over food safety, changes in how tuberculosis was understood, and to worries over diseased meat and the 'evils' of the urban meat trade. The Bovine Scourge explores the debates and fears that came to surround bovine TB, meat and public health between the 1860s and 1914. It traces how diseased meat and bovine TB emerged as a public health issue, examines the measures adopted to protect the public, and addresses how by the Edwardian era milk had become the major source of concern in discussion of bovine TB. It also raises important questions about the history of food safety, the concerns generated by diseased meat, and the role of the public health and veterinary profession in preventing the sale of contaminated food. KEIR WADDINGTON is a senior lecturerin the School of History and Archaeology at Cardiff University.

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discoveries and biological insights.

The First Cancer Systems Biology Book Designed for Computational and Experimental Biologists
Unusual in its dualistic approach, Cancer Systems Biology discusses the recent progress in the understanding of cancer systems biology at a time when more and more researchers and pharmaceutical companies are looking into a systems biology approach to find drugs that can effectively be used to treat cancer patients.

Includes Contributions from more than 30 International Experts
Part I introduces basic concepts and theories of systems biology and their applications in cancer research, including case studies of current efforts in cancer systems biology. Part II discusses basic cancer biology and cutting-edge topics of cancer research for computational biologists. In contains an overview of genomics, cell signaling, and tumorigenesis, in addition to hot topics like molecular mechanisms of cancer metastasis and the molecular relationships between solid tumors, their microenvironments, and tumor blood vessels. Rounding out the book's solid coverage, Part III explores a variety of computational tools and public data resources that are useful for studying cancer problems at a systems level.

Cancer systems biology is still in its infancy as a field of study, but it is fast becoming indispensable in the battle to defeat cancer and develop successful new treatments. Cancer Systems Biology marks an important step toward reaching that goal.

The current interest in prion diseases has been fueled by the panic that originated from the appearance of a new variant of Creutzfeldt-Jakob disease and the evidence linking it to human exposure to the bovine spongiform encephalopathy (BSE) agent. Peer-reviewed to assure accuracy, this book describes the science, concepts, hypothesis, and mechanisms of prion disease transmission. It covers human and animal prion diseases, their incidence, prevalence, origin, and clinical and neuropathologic characteristics. The author provides scientific facts and a clear explanation of the relevance and implications of the findings for science in general.

Originally published in 1976, this volume reports research that will help us to understand the causes of psychogenic diseases. It deals both experimentally and theoretically with the question of symptom specificity in psychosomatic research - why some individuals respond to psychological stress with gastric disorders, others with sexual impotence, and still others with high blood pressure. As the author notes in summarizing his conclusions, "The repeated pairing of activation of a given organic system with intense nervous stress directs the pathological influence of the stressor primarily upon the system activated; subsequently the natural stimuli which would ordinarily activate the system in a normal manner sustain the pathological stressor's effect as a conditioned stimulus for the stressor effect." The translation of this work from the original Russian brings to the attention of Western investigators new and useful models of stress-induced disorders, and sheds new light on the pervasive problem of psychosomatic disease.

This book is focused on the principals and methods of using growth layers formed in teeth and bones of mammals and to make a judgement on essential traits of the animal's life history. Nearly in all mammalian species including man, the age of individuals can be determined from the number of growth layers and, at least in some of them, it is possible to estimate the season of an animal's birth and death, the age of sexual maturation, periodicity of reproduction, certain feeding habits and other aspects of the individual's biology. It is also possible, from tooth enamel analysis, to assess dose of radiation accumulated by animals and human beings during their lifetime. The book is intended mainly for zoologists, wild-game biologists, and zoo-archaeologists, but some of the sections can also be of interest for anthropologists, radio-ecologists and conservation biologists.

This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and prevent them.
The chapters are written by internationally recognized scientists in their respective areas of disease, who work or have worked extensively in the most affected areas of the world. The emphasis for each zoonosis is on the epidemiology of the disease, the clinical syndromes and carrier states in infected animals and humans, and the most current methods for diagnosis and approaches to control. For infectious agents or biologic toxins, which may be transmitted by foods of animal origin, a strong focus is placed on food safety measures. The etiologic and therapeutic aspects of each disease important to epidemiology and control are identified.

This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and prevent them.
The chapters are written by internationally recognized scientists in their respective areas of disease, who work or have worked extensively in the most affected areas of the world. The emphasis for each zoonosis is on the epidemiology of the disease, the clinical syndromes and carrier states in infected animals and humans, and the most current methods for diagnosis and approaches to control. For infectious agents or biologic toxins, which may be transmitted by foods of animal origin, a strong focus is placed on food safety measures. The etiologic and therapeutic aspects of each disease important to epidemiology and control are identified.

Pathobiology of Marine and Estuarine Organisms is a comprehensive, up-to-date review of aquatic animal pathobiology covering infectious and non-infectious diseases of vertebrates such as marine mammals and fishes, in addition to diseases of invertebrates such as crustacea, mollusks, and lower phyla. The book provides critical information on viral, fungal, bacterial, parasitic, and neoplastic diseases of fish and invertebrates.

Written by top-notch experts in the field, Pathobiology of Marine and Estuarine Organisms emphasizes pollution-associated diseases and includes an important review on the effects of pollution on marine mammals. The book will be a welcome addition to the libraries of aquatic and marine biologists, aquatic toxicologists, fisheries biologists, aquaculturalists, fish and invertebrate pathologists, and aquatic animal parasitologists.

A vital read for anyone who cares about the future of British wildlife. With a foreword by the BBC TV presenter Chris Packham. 'A thriller, whodunnit and impassioned polemic.' - PATRICK BARKHAM, THE GUARDIAN Dominic Dyer explores the science and electioneering behind Britain's most controversial wildlife policy: the badger cull. He exposes the catastrophic handling of bovine TB by the British government, the political manoeuvring that engineered the badger cull in 2010, and the ongoing close relationship in perpetuating the cull between the National Farmers Union and the Department of the Environment, Food and Rural Affairs (DEFRA). He shines an unflattering spotlight on Cabinet ministers, the veterinary profession, environmental NGOs and the BBC. Reviews 'I enjoyed reading this book and I strongly recommend it to you. 'This is a powerful and stimulating read and it's bang up to date with the important issue it discusses. It is written by a passionate insider with years of experience. The narrative is pacey and exciting. This book arrived with me on Thursday afternoon and I had read it completely by early yesterday [Saturday] morning.' - MARK AVERY, WRITER, BLOGGER AND ENVIRONMENTAL CAMPAIGNER 'A vital must-read for anyone concerned about the badger's enduring place in the British countryside. 'A thriller, whodunnit and impassioned polemic, this is the inside story of the badger cull.' - PATRICK BARKHAM, THE GUARDIAN 'It should be read by all those battling against government policies that put money ahead of science and the environment. 'The book's conclusion is that the culls will be stopped, not by science or validity, but by cost. Yet Dyer remains optimistic: 'Despite all the incompetence, negligence and deceit, it's the caring compassionate British public who have made a stand for wildlife that gives me the most hope for the future.' 'His book pays tribute to the 'Badger Army', those many individuals from all walks of life who turned out to protest and importantly, once culling started, to protect the badgers out in the field. 'Those people will be patrolling the countryside, day and night, in every area where badger killing is taking place this autumn. While determined to protect their badgers, many also want to see the government help and support farmers to beat the TB in their cattle - but with proper cattle-based measures, not by senselessly killing wildlife.' - LESLEY DOCKSEY, THE ECOLOGIST, 'Why are our badgers 'Badgered to Death'?' Introduction by Chris Packham How viciously fickle we are. We arbitrarily pick and choose which species we like or dislike, normally and sadly based on purely anthropomorphic criteria, and then either laud or loathe them paying scant attention to the realities of their lives, or ours. And once cursed and demonised that tag is almost impossible to redress. Think rat, think fox... damned for historical crimes, firmly fixed as malevolent vermin, even in our supposedly enlightened age. But as this book displays we can also be quick to destroy the reputation of our animal heroes and blight their status with bigotry and ignorance. For many reasons we had come to love the badger, to cherish and admire it, to protect and celebrate it and of course many still do. But the reputation of this essential member of the UK's ecology has been targeted by a smear campaign which has been swallowed by the gullible and fuelled by those with vested interests. You see, in spite of all the science and all the truths that it outlines, the badger has become a scapegoat. Its been branded a 'bad guy' and is being persecuted as such. It's a terrible shame, but like I said, how fickle, how vicious, how predictably human. Buy the book and carry on reading Chris Packham's introduction

Fish is the principal source of protein for people in many parts of the world, particularly in developing countries. While most fish are caught from nature, aquaculture or fish farming is now making a significant contribution to total fish production. More intensive conditions of aquaculture often result in a higher incidence of fish diseases and disorders. As in the first edition, the focus of this second edition is on protozoan and metazoan parasites that cause disease in fish. Significant changes to this second edition include the addition of three new chapters and four of the original chapters have new authors.

The importance of food safety for human health has been widely recognized. The safety of foods of animal origin is particularly relevant because the large majority of foodborne diseases come from poultry, eggs, meat, milk and dairy products and fish. This textbook covers an integrated approach to this type of food production, hygiene and safety and shows how it results in concurrent benefits to animal well being, human health, protection of the environment and socioeconomics.

Globally, the way the animal production industry copes with infectious diseases is changing. The (excessive) use of antimicrobials is under debate and it is becoming standard practice to implement thorough biosecurity plans on farms to prevent the entry and spread of pathogenic micro-organisms. Not only in farm animal production, but also in facilities where companion animals are kept, including in veterinary practices and clinics, awareness of the beneficial implications of a good biosecurity plan has raised. The book Biosecurity in Animal Production and Veterinary Medicine is the first compilation of both fundamental aspects of biosecurity practices, and specific and practical information on the application of the biosecurity measures in different animal production and animal housing settings. The book starts with a general introductory chapter on the epidemiology of infectious diseases, followed by a chapter explaining the general principles of biosecurity. Specific topics of biosecurity, including rodent and insect control, cleaning and disinfection, hygiene and decontamination of feed, drinking water and air, and measuring the biosecurity status of farms, are detailed in dedicated chapters. Explanations on the relevance of the implementation of biosecurity plans in order to improve animal health and performance and reduce antimicrobial usage are described, and a chapter on ways to motivate farmers to implement a biosecurity plan has been included. Practical chapters deal with biosecurity in the poultry, pig and cattle industry, horse facilities, dog kennels, veterinary practices and clinics and laboratory animal facilities. The book is a practical guide that can be used by farm and animal facility managers, consultants, veterinarians, animal caretakers, and people with an interest in prevention of diseases in animals. Academics and students will benefit from the book because it contains all relevant information on animal biosecurity.

Poultry are a major source of valuable high-quality protein for much of the world's population, so food security is heavily dependent on maintaining poultry health. They are also increasingly important as specialist hobby animals in back-yard flocks. Despite this, veterinarians specializing in the care and health of these important domestic animals are few and far between, and many vets in small animal practice have little real experience of poultry health management and disease. Providing a comprehensive overview, this new handbook will help to plug this gap with 46 chapters of practical and accessible poultry health and management. The book: Covers the poultry industry, basic avian biology, infectious and non-infectious diseases and their agents, infection control, and disease investigation and legislation. Includes full colour images for ease of identification and diagnosis, in addition to practical guides to disease prevention. Considers areas of increasing global importance, such as antimicrobial resistance. Written by international experts, this book forms a valuable illustrated resource for veterinary professionals, veterinary students, or those entering the poultry industry.

Genetics has transformed plant pathology on two occasions: first when Mendelian genetics enabled the discovery that disease resistance was a heritable trait in plants, and secondly when Flor proposed the "gene-for-gene" hypothesis to explain his observations of plant-parasite interactions, based on his work on flax rust in North Dakota starting in the 1930s. Our knowledge of the genetics of disease resistance and host-pathogen coevolution is now entering a new phase as a result of the cloning of the first resistance genes. This book provides a broad review of recent developments in this important and expanding subject. Both agricultural and natural host-pathogen situations are addressed. While most of the book focuses on plant pathology, in the usual sense of the term embracing fungal, bacterial and viral pathogens, there is also consideration of parasitic plants and a chapter demonstrating lessons to be learnt from the mammalian immune system. Three overall themes are addressed: genetic analyses and utilization of resistance; population genetics; and cell biology and molecular genetics. Chapters are based on papers presented at the British Society for Plant Pathology Presidential meeting held in December 1995, but all have been revised and updated to mid-1996. Written by leading authorities from North America, Europe and Australia, the book represents an essential update for workers in plant genetics, breeding, biotechnology and pathology.

Immunity studies in sharks over the past three decades have produced some remarkable discoveries. If one message rings true, it is that alternative animal model systems, such as sharks and their relatives, have contributed very substantially to a better understanding of the development evolution of our own immune system. Immunobiology of the Shark describes the cellular, genetic, and molecular specifics of immune systems in sharks. Diverse approaches were employed to study the immunobiology of the shark from basic microscopic observations to detailed genome annotation. The book also raises a series of fascinating questions, which can be addressed experimentally using today's technology. This book will be a valuable resource for mainstream immunologists, comparative immunologists, geneticists, ecologists, evolutionary biologists, and investigators engaged in shark research. The book also aims to illustrate the magnificence of these animals as model systems and underscores the importance of their study to further understand their complex, and often enigmatic, biology.

This new volume of Methods in Cell Biology looks at methods for analyzing centrosomes and centrioles. Chapters cover such topics as methods to analyze centrosomes, centriole biogenesis and function in multi-ciliated cells, laser manipulation of centrosomes or CLEM, analysis of centrosomes in human cancers and tissues, proximity interaction techniques to study centrosomes, and genome engineering for creating conditional alleles in human cells.

Epilepsy is fairly unique among the various neurological disorders as it provides the neuroscientist with almost boundless opportunities to examine basic neurobiological mechanisms. Not surprisingly, advances in epilepsy research are closely tied to dev- opment of innovative neurobiological methodologies. In many cases the practical application of these innovations - especially in the context of a neurological disorder with anatomical, molecular, electrophysiological, and behavioral components such as epilepsy - can be found in the development of new animal models. In turn, our understanding of the pathogenesis of epilepsy (and new therapy development) greatly benefits from these models. Taking advantage of transgenic and homologous rec- binationtechniques,laboratorieshave recentlymovedbeyondthestandardconvulsant or stimulation models in rat to develop novel mouse models of epilepsy. This forward thinking approach has recently been applied to genetically tractable "simple" species such as Drosophila melanogaster (fruit flies), Caenorhabditis elegans (worms), Xenopus laevis (tadpoles), and Danio rerio (zebrafish). With contributions from prominent investigators in this field, this book provides a reviewoftheseemerginganimalmodelsofepilepsy. Priortextbooksdevotedtomodels of seizure and epilepsy almost exclusively categorized rat models with little attention paid to these more innovative approaches. Here we attempt to diverge from the conventionalepilepsyliteratureandfocusonanimalmodelsthatattempttoincorporate the latest technological advancements in neurobiology. While some of these models andapproaches are,admittedly, at veryearly stages ofdevelopment andmay ultimately fall short of widespread utilization, it is through the consideration and presentation of these models that the authors' hope to advance and challenge the field of epilepsy research.

Just like humans, animals and plants suffer from infectious diseases, which can critically threaten biodiversity. This book describes key studies that have driven our understanding of the ecology and evolution of wildlife diseases. Each chapter introduces the host and disease, and explains how that system has aided our general understanding of the evolution and spread of wildlife diseases, through the development and testing of important epidemiological and evolutionary theories. Questions addressed include: How do hosts and parasites co-evolve? What determines how fast a disease spreads through a population? How do co-infecting parasites interact? Why do hosts vary in parasite burden? Which factors determine parasite virulence and host resistance? How do parasites influence the spread of invasive species? How do we control infectious diseases in wildlife? This book will provide a valuable introduction to students new to the topic, and novel insights to researchers, professionals and policymakers working in the field.