Handbook of Mammalian Metabolism of Plant Compounds provides an extensive survey of how mammals metabolize compounds found in higher plants. Information about these compounds is important to researchers in pharmacology, toxicology, medical and natural products chemistry, and food sciences. Although there is plenty of literature about mammalian metabolism of plant compounds, it is scattered, and summaries of specific plant compounds are often difficult to obtain. This book contains 11 chapters discussing the metabolic fate of individual plant compounds grouped according to chemical class. It also features structural formulas of the compounds and their metabolites, including probable pathways of metabolism. This book provides a convenient single-volume reference source that will benefit all researchers requiring this type of information.

The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

With the staggering amount of pet health information available on the Internet, it is often difficult to find exactly what you are looking for. The Internet Guide to Pet Health is a one-stop guide that weeds through all the clutter to bring you only the most dependable sources and relevant content. This comprehensive compilation of annotated links will serve as a handy, useful, and easy-to-consult guide for persons who appreciate animals and/or own domestic pets of all kinds, especially cats and dogs. This text also features a full glossary of medical terms, bibliography, and a quick-find index. The health needs of pet animals have become as complex and specialized as those of humans. Pet owners, veterinarians, and animal lovers alike need authoritative, reliable, and up-to-date information about caring for the health and well-being of pets. The Internet Guide to Pet Health offers a quick, easy, and comprehensive reference to quality Web sites that focus on the health and welfare of animal companions. The Internet Guide to Pet Health will help you pinpoint reliable information on: * the health benefits of pet ownership * diseases transmitted by pets * pet food safety * animal care and welfare societies and organizations * death, dying, and euthanasia * poisons, dangerous situations, and other hazards * spaying and neutering * traveling with pets * pet-specific care for dogs, cats, small animals, and fish * surgery, surgical procedures, and hospitalization * exercise and training * dental care, diet, and nutrition * disabled pets * service and therapy animals * and much, much more! The Internet Guide to Pet Health is an ideal resource for anyone who is directly involved in the lives of pet companions or simply an animal lover. Medical librarians in academic medical centers and teaching hospitals; consumer health and public librarians; veterinarians and veterinary clinic staff; public health personnel; animal trainers; and groomers will also find this to be an invaluable text.

To study physiology is to examine how organisms have evolved solutions to the business of living in an inanimate world. Our world is and has always been dominated by physical and chemical forces. A physicist might tell us that all things are physical, while a chemist is more concerned with the elementary nature of reactions. A physical chemist sees the bonds between these views, and a biochemist draws out the organic symphony of the vital pathways. A structural biologist adds shape to the chemical building blocks of life, while a molecular biologist tinkers with these structures.This book is intended as a resource for students and researchers interested in developmental biology and physiology and specifically addresses the larval stages of fish. Fish larvae (and fish embryos) are not small juveniles or adults. Rather they are transitionary organisms that bridge the critical gap between the single-celled egg and sexually immature juvenile. Fish larvae represent the stage of the life cycle that is used for differentiation, feeding and distribution.This book aims at providing a single-volume treatise that explains how fish larvae develop and differentiate, how they regulate salt, water and acid-base balance, how they transport and exchange gases, acquire and utilise energy, how they sense their environment, and move in their aquatic medium, how they control and defend themselves, and finally how they grow up.

Since the popular first edition was published more than a decade ago, the number of swine used in toxicity studies has increased as an alternative to commonly used non-rodent species, such as dogs and primates. A volume in the Laboratory Animal Pocket Reference Series, The Laboratory Swine, Second Edition maintains the high standard set by the previous edition and is poised to continue its legacy as the premier laboratory reference on the care and use of swine in the laboratory. Emphasizes Humane Care and Use of Laboratory Swine Addressing the biology, husbandry, management, veterinary care and research applications of both large and miniature swine, this color reference is a complete source of information on the species. It is thoroughly updated and includes a major revision to the anesthetics section. It also places a heightened focus on animal welfare and addresses important considerations related to genetically modified swine. The book is divided into six parts: Important Biological Features examines everything from different breeds and behavior, to anatomical and physiological features, as well as digestive, cardiovascular, and pulmonary systems Husbandry addresses housing, nutrition, sanitation, transportation, and more Management and Quality Assurance looks at the impact of infections on animal research using swine, zoonotic diseases, legal regulations, genetic monitoring, and more Veterinary Care covers a variety of topics, such as clinical examination, diseases, pain recognition, and post-operative management Experimental Techniques addresses restraint, sampling techniques, basic surgical procedures, and other issues Resources provides extensive references for further study, including handbooks, journals, and websites

The first book to highlight research done by women of color in the field of shark science. A special emphasis is placed on amplifying the voices of Black, Indigenous, People of Color as well as artisanal fishers and economically disadvantaged coastal communities. Accessible to younger readers too, encouraging school children to get into marine science. Covers a broad range of topics including biology, ecology and evolution as well as some less talked about topics like outreach and stakeholder engagement. Interdisciplinary approach to shark science and conservation Easily digestible content for non-experts Focuses on a charismatic group of animals, sharks Offers diverse perspectives and cutting-edge research while diving into issues regarding the decolonization of shark science and changing public perception of sharks. This is an opportunity to challenge the notion that there is only one type of scientist or that scientists look and think a certain way.

Gives an account of the morphologies of vertebrate respiratory organs and attempts to explicate the basis of the common and different structural and functional designs and stratagems that have evolved for acquisition of molecular oxygen. The book has been written with a broad readership in mind: students of biology as well as experts in the disciplines of zoology, physiology, morphology, biological microscopy, biomedical engineering, and ecology and those that work or may contemplate working on materials and aspects concerning respiration in whole organisms will find it useful. Scientists in earth sciences with particular interest on the outcomes of past interactions between environmental factors (the physical domain) and evolution and adaptation (the biological domain), mechanisms that have set the composition, patterning, and anatomies of extant animal life, will find the book of interest.

The fifth edition of The Physiology of Fishes represents a compendium of knowledge across fish physiology, collecting up-to-date research into an easy-to-access single textbook. Written by the leaders in the field, it provides a comprehensive, accessible review of the core topics, integrating physiology with environmental science, ecology, evolution, and molecular cell biology. New chapters address Epigenetics, Biomechanics and Locomotion, and Behaviour and Learning. Each chapter contains an extensive bibliography, providing readers with the best sources from the primary literature. Almost three decades after the publication of the first edition, this book remains the only published single-volume work on fish physiology. The fifth edition provides an important reference for new students of fish biology, marine and freshwater biologists, ichthyologists, fisheries scientists, and comparative physiologists.

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. With contributions from an international selection of authors who are leaders in commercial infusion technology, Non-Clinical Vascular Infusion Technology, Volume II: The Techniques provides a current account of the techniques involved in all the major laboratory animal species for conducting successful vascular infusion studies with xenobiotics. Following in the footsteps of the highly praised Handbook of Pre-Clinical Continuous Intravenous Infusion, this new volume covers both up-to-date procedures and equipment. It is organized by species, including all those commonly used in pre-clinical studies: rat, mouse, dog, minipig, large primate, and marmoset. There are also chapters on juvenile studies and reproductive toxicity studies. Each section addresses the selection of the best model, surgical and non-surgical best practices, practical techniques, equipment selection, and commonly encountered background pathologies. Using a fresh approach, the authors identify best practices to be shared across the industry, and provide guidance on choices for the most acceptable methodologies from an animal welfare perspective. This volume, along with Volume I: The Science, provides a foundation of knowledge on infusion technology and its importance for safe clinical use of substances via this route of delivery. Features: Emphasizes best practices in accordance with the 3Rs-reduction, refinement, and replacement of animal usage in laboratories Presents step-by-step procedures and practical tips covering a wide range of common animal models, augmented by the liberal use of illustrations Covers modern practices and procedures in accordance with up-to-date equipment development

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. For the first time, the collective sciences involved in the understanding of this mode of drug delivery are brought together in one publication. Non-Clinical Vascular Infusion Technology, Volume I: The Science covers the scientific principles behind the delivery systems, from both physical and physiological standpoints. The book addresses body fluid dynamics, describes the scientific processes necessary to understand the various aspects of the physico-chemical issues relating to vascular infusion delivery, and discusses vascular infusion dynamics. It also considers all the essential elements of the preparation of a formulation intended for vascular delivery as well as assessment of compatibility of the formulation with the dosing apparatus. This volume, along with Volume II: The Techniques, provides a foundation of knowledge on infusion technology and its importance for safe clinical use of substances via this route of delivery. Features Identifies and shares best practices for non-clinical vascular infusion Presents modern practices and procedures in line with up-to-date equipment development Offers recommendations for in-life assessments in order to monitor the success or problems with the vascular infusion delivery Makes comparisons with human data in many areas

The present book deals with the biology of a wide range of coccidia of numerous genera including Emeria, Isospora, Sarcocystis, Toxoplasma, Caryospora, and Cryptosporidium. The book will be valuable for advanced undergraduates, graduate students, research workers, and teachers in biology, especially useful for parasitologists teaching the subject and essential for coccidiologists doing research on coccidia. The book has also an appeal for physicians, veterinarians, and zoologists needing an update of information in the general field of coccidiosis

The aim of the present volume was to give an overview over different available methodological approaches. The specialists may, perhaps, object that in their particular field the level of information is superficial. However, let them look at other chapters in which different approaches are discussed and which, surely, will appear less superficial from the more general point of view. We hope, at least, that crucial references can be traced throughout the book that would enable the readers to go in more detail when desired. It can be traced throughout the book that would enable the readers to go in more detail when desired. It was really one of our ideas to draw the survey of possibilities available. If this can stimulate the readers to use ideas to draw the survey of possibilities available. If this can stimulate the readers to use other methods that those they are routinely using the goals will be met.

The objective of this multi-authored compendium is, therefore, to bring together the state of arts reported in one place. Written by specialists by specialists in various fields of rondentology, and to suggest future lines of research. It is also felt that this work on rodent pest management will trigger more research effort for the benefit of mankind and help certain countries and organizations in revitalizing serious work in this field which, it appears, has dampened during the last few years.

The major objective of this handbook is to compile-in tabular form-the pharmacokinetic parameters of antimicrobial drugs used in food animals. This unique publication represents data from the FARAD (Food Animal Residue Avoidance Databank) databank, established by the authors under the auspices of the U.S.D.A. and contains significant amounts of previously unavailable information. This updated, one-of-a-kind volume even features additional data on laboratory rodents, dogs, cats, and horses in order to facilitate broader interspecies extrapolations. This easy-to-use reference is timely as well as invaluable to animal scientists, veterinarians, pharmacologists, and toxicologists who work with antimicrobials in chickens, turkeys, dairy and beef cattle, swine, goats, and sheep.

The unusual life history of the brine shrimp, Artemia, and the relative ease with which it can be experimentally manipulated have long made his crustacean a favorite system for biological studies. Over the years, descriptive morphological work has given way to a rigorous analysis of biochemical and cellular aspects of the organism. The underlying theme of the work is often been developmental in nature.This book brings together a wide spectrum of topics under study in the shrimp. Analyses of gene structure and protein synthesis are combined with descriptions of protein interactions characteristic of functional cells.

Bioenergetics is an emerging discipline which offers a more profound understanding of the ecology, behaviour, and evolution of wild herbivores. Increasingly, bioenergetic principles have been applied in management since they provide insight into population dynamics and are relevant to manipulation of habitats and assessment of the impacts of resource development. Growing interest in the agricultural potential of wild herbivores has provided further impetus. In spite of this promise, there are few comprehensive syntheses of the concept and its application to wild herbivores. This volume attempts to fill this need. This book provides a great amount of detail but its expressive aim is to lead us to the whole animal, to a herd, to population as integral parts of an ecological entity which in turn is the result of evolutionary forces.The concept of this book promises the realization of an overdue change in the approach to bioenergetics, to nutrition and husbandry, and thus to the management of wild herbivores: the final emancipation from rules and views based primarily on domesticated herbivores or on experimental animals held under unnatural conditions, necessarily impending them behaviourally, physically, and psychically.

The greatest challenge of our time is to produce sufficient food ot keep pace with the rapidly growing population. In the opinion of experts, during the next 25 years there will be a need for as much food as was produced in the entire history of mankind to date. Of the various measures available, improvement in agricultural productivity is judged as the ultimate means of augmenting food production and supplies. In this Handbook, an international team of experts consider the most important factors affecting production of both crops and livestock. This Handbook is intended as a scientific guide to practitioners and students, as well as to researchers, who should find here stimulating ideas for further exploration.

Egg transfer was first performed in 1890, but for half a century it received scant attention. However, since 1950 the technique has become increasingly widely used - in the laboratory for fundamental studies and more recently in practice, both veterinary and medical, to boost reproductive potential of genetically superior cattle and to overcome sterility due to impaired rubal function in women. As a result, a considerable body of literature has accumulated, totaling well in excess of a thousand references. But till now there has not been a single comprehensive text devoted solely to this subject. The present work was designed to meet that need at a time when the field is fast expanding with new techniques and approaches constantly being evolved. One need only cite the tremendous rate of progress in human egg transfer in the last three years. The work embraces laboratory and farm animals and primates, including man, altogether representing a total of 16 species.

Ear, Nose and Throat Diseases of the Dog and Cat is the ultimate reference for veterinarians and other professionals trying to diagnose and treat both common and less frequently diagnosed diseases and conditions of the ear, nose and throat. The book is divided into four sections: The Ear, The Nose, The Throat and Surgery of the Ear, Nose and Throat. Each of the first three sections begins by discussing anatomy and physiology and then reviews a wide variety of diagnostic procedures including video-endoscopic examination of the external ear canal, nose and throat, radiography and advanced imaging, and histopathological examination of biopsy samples. Chapters in each of the three sections then provide a detailed and extensive review of the diseases of the pinna, external ear canal, middle ear and inner ear - nasal planum, nasal cavities and sinuses and nasopharynx - pharynx and larynx. The final section opens with a chapter on perioperative management with subsequent chapters that cover surgery of the ear, nose and throat. Extensively referenced, and including nearly 500 color illustrations to assist in diagnosis and treatment, the book is an invaluable resource for both veterinarians in training and in practice for the accurate diagnosis and management of diseases of the ear, nose and throat.

* Classifies and describes different orders and families of rumen ciliate protozoa* Describes morphological features and how they are used to identify protozoa* Features line drawings, created by the author, of various rumen protozoa with all morphological features and size measurements

Sources of clinical treatment information on nonhuman primates are generally scattered across journals, textbooks, conferences, personal conversations, and more. However, when a clinician on the treatment floor is faced with a patient requiring an immediate treatment decision, time spent on making an informed decision becomes a critical factor. An alternative to conducting a literature search in time-sensitive situations, the Pocket Handbook of Nonhuman Primate Clinical Medicine supplies guidance and initial direction on diagnosis and treatment, including working doses based on past case experience. It is the frank, to-the-point nature of the writing that makes readers feel as if they had just asked a colleague how to approach a clinical problem and obtained a quick, "what you need to know" answer. The chapter authors draw on personal experience to describe commonly encountered clinical conditions and how to treat these cases including not only the "dos" but also the "don ts." This format gives readers easy access to clinical signs, diagnostic criteria, and options for treatment. The Pocket Handbook of Nonhuman Primate Clinical Medicine is a convenient, concise, case-based handbook written by and for clinicians in charge of the diagnosis and treatment of nonhuman primate patients. Available in both print and electronic formats, this handbook saves readers from having to wade through pages of data and case studies to find answers when time is a factor on the clinic floor.

Handbook of Mammalian Metabolism of Plant Compounds provides an extensive survey of how mammals metabolize compounds found in higher plants. Information about these compounds is important to researchers in pharmacology, toxicology, medical and natural products chemistry, and food sciences. Although there is plenty of literature about mammalian metabolism of plant compounds, it is scattered, and summaries of specific plant compounds are often difficult to obtain. This book contains 11 chapters discussing the metabolic fate of individual plant compounds grouped according to chemical class. It also features structural formulas of the compounds and their metabolites, including probable pathways of metabolism. This book provides a convenient single-volume reference source that will benefit all researchers requiring this type of information.

Handbook of Comparative Pharmacokinetics and Residues of Veterinary Therapeutic Drugs is a unique compilation of comparative pharmacokinetic data for veterinary therapeutic drugs. The book features an excellent introductory chapter on basic veterinary pharmacokinetics and includes pharmacological data taken from hundreds of primary research references. These data are presented in standardized units and are arranged in conveniently organized tables so that comparisons between data can be made easily. Much of the data is new and was taken from articles in which data was not subjected to pharmacokinetic analysis.

A major problem with vampire bats is that whatever information exists is scattered throughout the literature or is not recorded. There are some excellent books on the ecology and biology of bats with very little on vampire bats. This volume fills that gap to provide an in-depth presentation of these unique animals.

Laboratory animals, including birds, play an important role in biomedical research. The humane care and management of these animals is an ongoing concern. A new addition to the acclaimed Laboratory Animal Pocket Reference series, The Laboratory Bird is the first publication dedicated to the care and use of avian species in the research setting. Covering avian species such as chickens, ducks, doves, parrots, and songbirds that are commonly used as research models, the book is divided into focused chapters that cover a broad range of topics, including: General avian biology and physiology Husbandry Regulations and regulatory compliance regarding the use of birds in research Experimental methods Veterinary care Along with discussing applicable regulations, the book also details issues of health management and quarantine approaches. The final chapter provides resources such as organizations, publications, vendors, and diagnostic laboratories. With its focus on the care of a diverse group of avian species in biomedical research settings, The Laboratory Bird is a valuable reference for animal care and veterinary technicians, laboratory animal veterinarians, trainees in laboratory animal medicine, and research staff members, as well as individuals involved in laboratory work who lack experience in working with birds.