There is increasing concern in the media, among politicians and within environmental organizations, about the effects of chemicals in our environment that affect the endocrine systems of wildlife and humans. At its simplest these are referred to as gender-bending' chemicals or environmental estrogens'. The chemicals in question (pesticides, PCBs, plasticizers, petrochemicals, and a variety of industrial chemicals) have been known to decrease human sperm counts, cause fish to change sex', and increase male genital abnormalities. A great deal of pressure has been placed on environmental protection agencies to devise regulatory tests for the effects of these chemicals and to require limitations on their manufacture and release. Fish are increasingly recognized as an excellent model for such tests, in that the aquatic environment may provide early warnings of the effects that these chemicals will have on human health. In addition, the large number of eggs which fish produce provides an excellent model to examine the effects on female fertility. Endocrine Disruption in Fish provides a simple yet extensive background to the field of fish endocrinology in order to assist those toxicologists who have a limited background in either mammalian or fish endocrinology. It shows that environmental estrogens do not simply affect male reproductive potential, but that they may equally well affect the female. It is possible that these chemicals may have a complex effect on the brain, hypothalamus, pituitary, gonad and liver of both sexes. There are many other chemicals which affect both the gonads and other parts of the endocrine system to cause decreased fertility, abnormal sexual differentiation andbehavior, decreased response to stress, immune deficiency or altered basal metabolism. Many thousand man-made chemicals are released into the environment, but very few have been tested for endocrine disrupting activity. This book covers only the minute fraction for which evidence has been collected.

This book reviews all major models and hypotheses concerning the mechanisms supposed to underlie the process of navigation in vertebrates.

It covers data on all major model groups of vertebrates studied in the context of animal navigation, such as migratory birds, homing pigeons, sea turtles, subterranean mammals and some migratory fish species. Some other - less studied - groups, e.g., whales, have also been touched.

The first part of the book describes different sources of navigational information, with their specific navigational mechanisms known or supposed to be employed by animals for navigational goals. The second part discusses possible functions of these mechanisms in different vertebrates and in the context of different navigational tasks, ranging from short-range navigation, often performed by animals within as small an area as several square meters, to long-distance global-scale migrations performed by many birds and some sea turtles during their lifespan.

Every coordination within or between animals depends on communication processes. Although the signaling molecules, vocal and tactile signs, gestures and its combinations differ throughout all species according their evolutionary origins and variety of adaptation processes, certain levels of biocommunication can be found in all animal species:

(a) Abiotic environmental indices such as temperature, light, water, etc. that affect the local ecosphere of an organism and are sensed, interpreted.

(b) Trans-specific communication with non-related organisms.

(c) Species-specific communication between same or related species.

(d) Intraorganismic communication, i.e., sign-mediated coordination within the body of the organism.

This book gives an overview of the manifold levels of animal communication exemplified by a variety of species and thereby broadens the understanding of these organisms.

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This is the first book devoted to international deer husbandry techniques for the growing industries of venison, velvet antler, and antler trophy production as well as long established extensive park systems for amenity. Written by world leaders in their specialised subjects, chapters shed light on widely differing management systems and the optimum design of deer farms, handling yards and fencing layouts. Moreover, readers will discover the requisites of good stockmanship and specialist veterinarians describe different diseases the deer may develop. Details on available treatments, the general biology of deer and an explanation of controversial ethics of velvet and trophy production complete this work. As deer farming has come of age this collection is timely. At fifty years the New Zealand deer industry carries one million animals with annual venison exports to America, Europe and growing antler markets in China and Korea. Chinese antler production is well-established and Asian reindeer husbandry even more ancient. In North America and Europe, deer are now being kept for antler trophies and amenity in many historic parks. This volume is a valuable resource for everyone researching deer management systems, be it practising veterinarians, deer farmers, park managers or agricultural and veterinary students.

A presentation of the most elementary form of pulsatile flow as an important prerequisite for the study of other flow applications in biological systems. The book provides in a single source a complete treatment of the fluid dynamics of flow with the required mathematics and emphasis on the basis mechanics. The style and level of this book make it accessible to students and researchers in biophysics, biology, medicine, bioengineering and applied mathematics working in theoretical and clinical work on the cardiovascular system, as well as in the design of new instrumentation, medical imaging systems, and artificial organs. With problems and exercises.

An integrated reference which could form the basis for advanced courses on development or become a resource for individuals teaching basic courses. Following an introduction by the volume editors, the 11 chapters represent 11 different systems, arranged phylogenetically, beginning with prokaryotic s

A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

This title includes a number of Open Access chapters. This book looks at a range of topics covering a variety of animals, including how macaques teach their offspring, how rats transmit avoidance behavior, how supplementary feeding of tree frogs affects their breeding behavior, and more. Studies in animal behavior can have far-reaching implications for animals and humans alike, such as how humans can improve conservation efforts, how to better protect animals-both in the wild and in captivity (zoos), and what can be learned about humans from animals, such as how the human brain and behaviors might work.

In this volume of Reviews of Physiology there are three outstanding contributions, the first on Selenium-containing proteins in mammals and other forms of life, and the second on constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0 and the third on Chloroplast quest: a journey from the cytosol into the chloroplast and beyond.

This volume covers a wide range of model systems from invertebrate to humans and in vitro and in vivo. Chapters detail methods on squid, aplysia, xenopus, mouse in vivo, ex vivo, rodent primary neurons, human-derived neurons, zebrafish, drosophila in vivo, primary neurons, c. elegans, and in vitro reconstitution assays.Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Axonal Transport: Methods and Protocols aims to further our understanding of the trafficking of cellular components in the nervous system leading to the advancement of basic knowledge that underlines the cell biology of the neuron. The chapters " Live imaging of RNA Transport and Translation in Xenopus Retinal Axons, Retrograde Axonal Transport of Neurotrophins in Basal Forebrain Cholinergic Neurons, Assessment of Mitochondrial Trafficking as A Surrogate of Fast Axonal Transport in Human Induced Pluripotent Stem Cell Derived Spinal Motor Neurons, Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport, and In vitro Reconstitution of Kinesin-Based, Axonal mRNA Transport" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com

This book is an inclusive coverage of advances in aquaculture health management. It offers latest updates as well as explains the novel concepts and issues related to aquatic animal health management. To support the understanding of the concepts, there is extensive use of illustrations. Chapters emphasize on the state of art techniques and hold great promise for the sustainable development of aquaculture. This book is of interest to teachers, researchers, aquatic biologists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of aquatic sciences, marine sciences, biotechnology, ecology, and environmental sciences. National and international aquatic scientists, policy makers will also find this to be a useful read.

The study of primate locomotion is a unique discipline that by its nature is interdis ciplinary, drawing on and integrating research from ethology, ecology, comparative anat omy, physiology, biomechanics, paleontology, etc. When combined and focused on particular problems this diversity of approaches permits unparalleled insight into critical aspects of our evolutionary past and into a major component of the behavioral repertoire of all animals. Unfortunately, because of the structure of academia, integration of these different approaches is a rare phenomenon. For instance, papers on primate behavior tend to be published in separate specialist journals and read by subgroups of anthropologists and zoologists, thus precluding critical syntheses. In the spring of 1995 we overcame this compartmentalization by organizing a con ference that brought together experts with many different perspectives on primate locomo tion to address the current state of the field and to consider where we go from here. The conference, Primate Locomotion-1995, took place thirty years after the pioneering confer ence on the same topic that was convened by the late Warren G. Kinzey at Davis in 1965."

During the past quarter century, there has been a tremendous expansion in our knowledge about gastropods, their behavior and their neurobiology. We can understand a great deal about mammaliam nervous systems by studying the relatively larger and simpler structure of the gastropod nervous system. Behavior and its Neural Control in Gastropod Molluscs first reviews the broader aspects of molluscan biology and draws attention to the special features of the gastropod nervous system. The book then examines different types of behavior, reviewing progress in understanding the mechanisms of neural control, and emphasizing cases in which control can be attributed to identified neurons and indentified neural circuits.

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks.

The book is intended to provide in-depth reviews of the recent advances in major areas of metabolism in growing domestic animals. The study of metabolism represents a nexus of biological phenomenon that integrates the impact of nutrition, physiology, endocrinology, immunology, biochemistry, and cell biology in an organism. The development of new methodological techniques and experimental approaches have provide scientists with a greater understanding of how key nutrients or substrates are metabolized at the cellular, organ, and whole animal level. This book presents contributions from leading scientists in nutrition and physiology that highlight important new developments in interorgan and tissue-specific metabolism of protein and amino acids, lipids and fatty acids, and carbohydrates in monogastric and runinant species. Authors will describe the impact of specific biochemical pathways and expression of critical enzymes, routes of nutrient or substrate input, and anatomical or structural influences on the rates of metabolism in a given tissue or cell type. Major substrates/ fuels for oxidative metabolism, key signaling pathways, and intracellular molecules that regulate the major metabolic processes will be described. Also included is how the metabolism of growing animals is influenced by ontogeny, stage of differentiation, and major changes in diet, or the environment. The concepts and specific findings in each area are discussed in the context of their impact on the nutrient requirements, growth, environmental impact, healt and well-being of animals. The book will be a useful reference for research scientists, teachers and students interested in and advanced understanding of metabolism in growing animals. The book is written by leading experts and highlights some of the most recent advances in the field of metabolism. It is a useful reference for researchers and advanced level graduate students in nutrition, physiology and animal science. Presents recent advances in the field of metabolism.

Many complex molecular interactions are involved in the development of the mammalian brain. Molecules serving as guidance cues for migratory cells, growing axons and for recognition of postsynaptic targets are a major topic for research because they are directly involved in the formation of neuronal circuits, thus creating the foundation for subsequent functional refinement through interactions with the environment. In addition, most guidance cue molecules are also involved in plasticity, damage repair and regeneration in the adult brain. This volume reviews current knowledge on major classes of molecules involved in: guidance of growing axons; tau proteins involved in the establishment of axonal polarity, outgrowth and contact recognition; gangliosides and lectins involved in neuronal migration, neurite outgrowth and contact recognition; and myelin molecules that inhibit nerve regeneration.

This unique volume gives insight into the science of slaughter with in-depth discussion of neural communication and the welfare aspects of pre-slaughter handling and slaughter of livestock. The concepts of conscious perception, unconsciousness, stunning, slaughter and death are discussed to provide readers with an understanding of the different events that lead to the conversion of animals into carcasses and subsequently into meat. This accessible work is an excellent resource for learning about welfare issues of different techniques, as it includes historical aspects of religious and conventional slaughter with a focus on the developments around technologies. It comprises the advent of mechanical slaughter in the form of poleaxes to present day use of sophisticated stunning equipment. Moreover, the author covers key aspects of halal meat production and discusses the politics of religious slaughter with an emphasis on the increasing number of anti-halal movements across Europe, America and others. The slaughter of animals for consumption by people of faith is economically significant and has led to a race for market share by multinational retail enterprises. However, there are also ethical and political aspects of religious slaughter which have always divided opinion. The topic of this book provides an important link to the disciplines of animal welfare research, the meat industry and the food business. Scientists, students, as well as government agencies, veterinarians and professionals in food processing and slaughter technology manufacturing will find this an important account. Simplified summaries and practical notes make this reference highly readable.

Animals perform many athletic tasks to an amazing degree of accomplishment: not only spectacular feats of running and jumping but also routine actions that ensure survival such as feeding, vocalization, diving, flying, and many more. The study of performance capacity (defined as the ability of an animal to conduct a key task) is of great interest to both ecologists and evolutionary biologists. At an ecological level, how well individuals perform often dictates opportunities for reproduction, occupation of preferred territories, or capturing prey. Therefore, variation in performance capacities can be a key determinant of variation in fitness within animal populations. At an evolutionary level, variation in function often follows closely from variation in form, and therefore enables animals to invade novel habitats, or to overtake other species. This novel book examines how and why animal athletes have evolved. It uses examples from across the animal kingdom and integrates them in the broader context of ecology and evolution, thereby identifying common themes that transcend taxonomic divisions. Animal Athletes is an accessible textbook of particular relevance to undergraduates, graduate students, researchers, and professionals in the fields of evolutionary biology, ecology, vertebrate morphology, and functional, morphology,and will also appeal to the interested layperson.

As a group, carp provide 4 million metric tonnes of fish annually - over a quarter of all fish culture worldwide. For the first time, a book is available in English that concentrates solely on the carp as an economic rather than an ornamental fish with a panel of international experts producing a comprehensive, practical volume about carp production and management. Starting with a brief look at the biology of cyprinids, the book then discusses the methods and management of carp farming, from water quality to the economics of fish production in ponds. Novel methods to improve stock, including genetic engineering, are covered and case studies give added value to the text. As carp farming turns from traditional to intensive methods, farmers, researchers and technicians in industry will welcome this benchmark volume, which also is a valuable reference book for graduate and postgraduate students and lecturers in aquaculture.

This book discusses how and why animals evolved into particular shapes. The book identifies the physical laws which decide over the evolutionary (selective) value of body shape and morphological characters. Comparing the mechanical necessities with morphological details, the author attempts to understand how evolution works, and which sorts of limitations are set by selection. The book explains morphological traits in more biomechanical detail without getting lost in physics, or in methods. Most emphasis is placed on the proximate question, namely the identification of the mechanical stresses which must be sustained by the respective body parts, when they move the body or its parts against resistance. In the first part of the book the focus is on 'primitive' animals and later on the emphasis shifts to highly specialized mammals. Readers will learn more about living and fossil animals. A section of the book is dedicated to human evolution but not to produce another evolutionary tree, nor to refine a former one, but to contribute to answering the question: "WHY early humans have developed their particular body shape".

This is the first book focusing on the animal's perspective and best practices to ensure the welfare of both therapy animals and their human counterparts in animal-assisted interventions. Written by leading scientists, it summarizes the scientific evidence available concerning the impacts on animals in these settings, including companion species, horses, marine mammals and other animals used in therapy. There has been a dramatic increase in the range of animal-assisted interventions used in medical and allied health environments in recent years, and the field is now entering an era with a greater interest in defining the underlying mechanisms of the human-animal bond as well as the therapeutic benefits of these interactions. Animal-assisted interventions, as with other uses of animals by humans, impose a unique set of stresses on the animals, which the community has only recently begun to acknowledge. For the field to continue to flourish, more evidence is needed to shed light on the implications for the animals and what guidelines need to be put into practice to ensure welfare. With the ultimate goal of improving the impact that we have on the animals under our care, the book provides a roadmap for researchers and clinicians as they attempt to safely and humanely incorporate various species of animals into therapeutic settings. The authors also offer instructions and suggestions for areas that need to be studied more robustly over the next decade to continue to ensure the safe and proper use of animals in therapy sessions. This is an informative, thought-provoking and instructive resource for practitioners and researchers in the field of medicine and clinical psychology using animal-assisted interventions, as well as for veterinarians and welfare scientists.

Strategies for Successful Animal Shelters is the first book to assess the relationship between shelter traits, activities and critical outcome variables, such as live release or save rates. This book provides a data-based evaluation of shelter processes and practices with explicit recommendations for improved shelter activities. Using a survey of licensed animal shelters, case studies, and data on state inspections, complaints, and save rates, this book provides an assessment of the activities, processes, and procedures that are most likely to lead to positive outcomes for a variety of animal shelters. The book also contributes to community debate around animal sheltering and provides best practices, methods and means to assess local shelters to ensure the highest level of animal welfare. It is a valuable resource for animal shelter professionals and rescue groups, as well as students in disciplines such as animal science, animal welfare and shelter medicine.

This publication contains the proceedings of a seminar 'The problems of dark-cutting in beef' held by the Commission of the European Communities (CEC) at the Commission in Brussels on 7 and 8 October 1980. As part of the CEC programme of coordination of agricultural research, this meeting was organised in the framework of the beef and animal welfare activities by Dr. D.E. Hood and Dr. P.V. Tarrant, Meat Research Department, An Faras Taluntais. Dunsinea, Castleknock, Dublin, Ireland. The proceedings, edited by the organisers assisted by Janssen Services, 33a, High Street, Chislehurst, Kent, UK, provide an authoritative text-book on this important aspect of meat technology. Reduction of pre-slaughter stress and improvement in carcass and meat quality is becoming increasingly important in the international meat trade. This results in particular from growing consumer concern about the welfare of meat animals during the pre-slaughter period and from specific meat packaging and marketing requirements. Technical development of the beef processing industry is dependent on a uniformly high level of meat quality in the raw material.

This straightforward, easily understandable primer details the principles and practices of genetics as they relate to fish farming. After reviewing basic genetic principles and the genetics of sex determination, this book focuses on the genetics of qualitative traits and profiles selection programs that produce true breeding populations. It also considers quantitative issues, broodstock management, genetic engineering, chromosomal manipulation and electrophoresis.

It has been established that neuroglia are involved in early neu- ronal growth, differentiation, and migration; these issues are well discussed in the companion volume entitled Neuron-Glia Interrela- tions During Phylogeny: I. Phylogeny and Ontogeny of Glial Cells. The present volume, Neuron-Glia Interrelations During Phylogeny: II. Plas- ticity and Regeneration, focuses on two aspects: (1) neuron-glia inter- relations as they relate to the physiological and metabolic homeostasis of neurons; and (2) the role of neuroglia and neuronal plasticity in regeneration and aging. Neuron-Glia Interrelations During Phylogeny: II. Plasticity and Regeneration begins with the unique presentation, "Neuron-Glia In- teractions in the Human Fetal Brain," by Sogos et al. The interesting issue discussed in this chapter is the immunocompetence of the CNS, a field that is now rising. The chapter by Oland et al. , "Glial Cells Playa Key Role in the Construction of Insect Olfactory Glomeruli," discusses a unique role of glial cells as intermediates in afferent- axon induction of substructure with the CNS. The chapter by Vanhems, "Insect Glial Cells and Their Relationships with Neurons," compliments the information presented in the companion volume by Fredieu and Mahowald and, in this volume, the chapter by Tobert and Oland. The chapter by Tsacopoulos and Poitry, "Metabolite Exchanges and Signal Trafficking Between Glial Cells and Neurons in the Insect Retina," provides evidence of the nutritive functions of glial cells and the important role of alanine supplied by glial cells to photoreceptors, a clear neuron-glia interaction.