The symposium on Acoustical Signal Processing in the Central Auditory System which was held in Prague on September 4--7, 1996 was the third in a series organized in Prague, after the Neuronal Mechanisms of Hearing symposium in 1980 and Auditory Pathway - Structure and Function symposium in 1987. Approximately 100 scientists regis tered for the symposium and presented 82 separate papers and posters. The present vol ume contains 53 of these contributions, mostly presented at the symposium as invited review papers. Several essential changes occurred since the previous meeting in 1987. In auditory neuroscience, recently developed methods opened new horizons in the investigation of the structure and function of the central auditory pathway. Methods like c-fos tracing tech niques and monoclonal antibodies for neurotransmitters and their receptors, like the intro duction of electrophysiological recording from brain slices have made possible new insights into the function of individual neurons and their interconnections, particularly in the cochlear nuclei and in the superior olivary complex. Integrative approaches towards understanding the central auditory function started to dominate in the field. It is not easy at the present time to differentiate between purely morphological and neurochemical ap proaches; similarly electrophysiological approaches are accompanied inevitably by behav ioral and psychophysical studies. The understanding of human brain function advanced significantly during the last several years. mainly due to the contribution of magneto encephalography. positron emission tomography and functional nuclear magnetic reso nance imaging.

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on hormone and transport systems.

This detailed volume presents a wide range of techniques that go beyond the standard assays typically used to assess Myogenesis. The content included addresses assays to analyze skeletal muscle gene expression, proliferating muscle cells, the process of myoblast fusion, muscle development (in vivo), as well as muscle repair. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Skeletal Muscle Development serves as an ideal guide to the study of this highly complex yet carefully regulated process.>

-- This new edition offers significant new information, regarding new technologies like CRISPR-Cas, new housing systems and management practices (including metabolic cages), a table on injection volumes and recommended needle sizes, info on new concepts such as pain assessment by facial expression, possible anesthetic reversal agents, and the potential impact of common procedures on animal welfare. The regulatory section has been entirely updated. The book is now more relevant to an international audience, addressing differing regulations across borders. -- With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. These researchers and their lab technicians need a handy, quick and up-to-date reference guide to inform them of best practice when working with these animals. -- Unlike existing books on laboratory mice, this book focuses not only on veterinary medicine but also offers detailed information regarding management and behavior of mice. It also offers a concise synopsis of material relevant to those working with, and caring for, laboratory mice, making for an easily-used reference.

While there are several recent books on this emerging field, Veterinary Forensic Medicine and Forensic Sciences sets the bar, covering all relevant aspects in a succinct, easy-to-read, comprehensive format designed to be taught in a single-semester course. Intended to be the premier textbook on veterinary forensic sciences, the book covers the application of veterinary forensic medicine to cases, including the medical perspective as well as law enforcement response, crime scene management, and evidence recovery issues. Coverage includes the scientific and legal principles for veterinary forensic evidence. This clearly delineates it from veterinary-only practices, since the forensic aspects present additional challenges that include evidence recovery and preservation, report writing, and maintaining an evidentiary chain of custody, all the way through expert witness testimony. Some emerging topics that are covered include DNA and genetic evidence, entomological evidence in support of veterinary forensics, animal fighting, situational deaths, including poisonings, domestic violence, and cruelty, sharp and blunt force trauma, gunshot and wound ballistics, sexual assault, nonhuman odontology and osteology, and more. Features Details a process for forensic science case management for humane law enforcement agencies Presents multiple chapters on specific types of trauma analysis in animals Provides developments on current trends in forensic entomology as applied to wildlife crime and minimum postmortem interval determinations Explores national and international considerations in combating organized animal fighting Offers DNA applications for wildlife crime and environmental monitoring Outlines current animal and environmental forensic toxicology legal casework This text offers a straightforward presentation of current practices and includes several real-world case examples throughout to illustrate concepts. Fully illustrated with more than 280 full-color images, Veterinary Forensic Medicine and Forensic Sciences provides the latest in advances and up-to-date field techniques, applicable for student instruction in the classroom and beyond.

The annual Congress of the Italian Biochemical and Molecular Biology Society (SIB) was held in September 1999 in Alghero, Sardegna, Italy. The programme envisaged a symposium on molecular adaptations of haemoglobin function in ver- tebrates. Haemoglobin specialists from several countries were invited to speak at the symposium and paved the way for wide-ranging and stimulating discussions. The symposium contributions have been collected together in this volume. The structure/function relationship in haemoglobins from vertebrates (fishes populat- ing temperate and polar environments, diving birds, marine and terrestrial mam- mals) has been tackled from many angles, focusing on the adaptation of the oxy- gen-transport system to the constraints dictated by the environment. Eleven arti- cles review some of the most recent developments of the studies on this ancient oxygen-transport protein, characterized by high conservation during evolution. The volume offers the reader an updated, state-of-the-art summary of a field that is enjoying a true renaissance. Covering the topic from several viewpoints, the volume includes protein chemistry (amino acid sequence, secondary, tertiary and quaternary structures, thermodynamics of oxygen-binding features), molecular biology (globin gene structure, sequence, organization, expression and regulation) and evolution. In this representation of effective multidisciplinary and multina- tional collaborative efforts, reference is available to a wide range of disciplines and biological systems. The tools of the investigators comprise advanced and powerful methodologies developed in recent years, e. g.

This volume provides an introduction to Borelli s theory on the movement of animals and demonstrates the nature of the energy of percussion, its causes, properties and effects. Building on and moving away from the theory of mechanics as formulated by Aristotle and Galileo and countering objections expressed by Stephani degli Angeli among others, Borelli presents a completely mechanical account of the action of muscles and analyzes the way in which the center of gravity of the animal shifts in locomotion.

Originally published in Italian in 1667, then translated into Latin in 1686, the text of this volume has now been translated into English, making the text accessible to a wide readership.

This volume is the first of two volumes that contain the Introduction and physical-mathematical illustrations necessary to understand Giovanni Alfonso Borelli s work "On the Movement of Animals, " the founding text of seventeenth century biomechanics. The second volume, entitled"On The Natural Motions Resulting From Gravity, "describes his theory and scientific experiments relating to the natural movements of bodies in a fluid environment."

This book describes the importance of sustainable livestock production from a food security perspective in the changing climate scenario. It covers the amelioration of climate change impacts and describes the various mitigation strategies to reduce enteric methane emissions. The book targets sustainable livestock production by covering diverse concepts of amelioration, mitigation, and policy up-gradation. Further, it examines various adverse impacts of climate change on growth, meat, milk, and reproduction in livestock. Most importantly, the book covers novel aspects of quantifying heat stress response of livestock based on non-invasive methodologies, including infrared thermal imaging, sensor-based applications, hair, urine, and fecal cortisol estimation. Particular emphasis was given to describing the skin-based novel approaches to establish climate resilience in indigenous breeds. The book provides detailed descriptions of alleviating climate change impacts on shelter management, nutritional interventions, and genetics-based strategies involving advanced genomic tools. Lastly, it highlights the livestock species which could be considered ideal climate-resilient animal models to withstand the adversities associated with climate change.

This is the Second Edition of a well-received book that reflects a fresh, integrated coverage of the concepts and scientific measurement of stress and welfare of animals including humans. This book explains the basic biological principles of coping with many forms of adversity. The major part of this work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of welfare indicators are highlighted in detail with examples being drawn from man and other species. The necessity for combining information from disciplines is emphasized with a one-health, one-welfare approach. This information forms the basis for a synthesis of new ideas. Among the issues covered are: - How brain and body systems regulate using feelings, physiological responses, behaviour and responses to pathology - Limits to adaptation - Assessing positive and negative welfare during both short-term and long-term situations - Ethical problems and suggested solutions A proper assessment of animal welfare is essential to take informed decisions about what is morally acceptable in terms of practice and in the development of a more effective legislation. This work encapsulates a very wide body of literature on scientific aspects of animal welfare and will thus prove a valuable asset for animal welfare scientists, psychologists, students and teachers of all forms of biology, behaviour, medicine, veterinary medicine and animal usage.

The history of Science is replete with untold stories and this book is one of these accounts. The author shares a narrative of heredity, an active topic of inquiry long before Gregor Mendel - the father of genetics - planted his peas. One such interlude unfolded in Mendel's home city and involved the sheep breeder, Imre Festetics. He sought to improve wool and proposed important rules of heredity. Unfortunately, aspects of wool quality, now known to be polygenic, complicate interpretations of the work of Festetics and explain why it is neglected. The forebearers of Mendel never get the credit they deserve. Heredity Before Mendel resurrects Festetics, the grandfather of heredity. Key Features 1) Documents a vibrant community of scholars interested in heredity before Mendel 2) Highlights the work of Imre Festetics, the forgotten grandfather of genetics 3) Desribes political repression which stifled the nascent foundation of heredity research 4) Emphasizes the role sheep and wool played as the first model system of genetics 5) Challenges19th century taboos in Moravia leading to malicious rumors about the inbred royal House of Austria (Habsburgs).

Here, experts in different areas of the field provide an overview of the bioacoustics of whales and dolphins as well as a thorough introduction to the subject for investigators of hearing in other animals. Topics covered include the structure and function of cetacean auditory systems, the unique sound production system of odontocetes, acoustic communication, psychoacoustics, echolocation and models of sound propagation.

The Teeth of Non-Mammalian Vertebrates is the first comprehensive publication devoted to the teeth and dentitions of living fishes, amphibians and reptiles. The book presents a comprehensive survey of the amazing variety of tooth forms among non-mammalian vertebrates, based on descriptions of approximately 400 species belonging to about 160 families. The text is lavishly illustrated with more than 600 high-quality color and monochrome photographs of specimens gathered from top museums and research workers from around the world, supplemented by radiographs and micro-CT images. This stimulating work discusses the functional morphology of feeding, the attachment of teeth, and the relationship of tooth form to function, with each chapter accompanied by a comprehensive, up-to-date reference list. Following the descriptions of the teeth and dentitions in each class, four chapters review current topics with considerable research activity: tooth development; tooth replacement; and the structure, formation and evolution of the dental hard tissues. This timely book, authored by internationally recognized teachers and researchers in the field, also reflects the resurgence of interest in the dentitions of non-mammalian vertebrates as experimental systems to help understand genetic changes in evolution of teeth and jaws.

This book presents a concept for implementing a mass balance approach toward developing an effective eco-friendly, livestock farming system independent of external energy input. In this context it describes a modern, integrated farming system, and includes comprehensive technical information explaining the design and evaluation of manure management systems, and modeling and operational tools. It first discusses the mass balance operating process, highlighting the difference between imported and exported mass across the farm boundary. Estimating mass balance can provide critical information for (comprehensive) nutrient management planning and for managing the movement of nutrients and manure. It then explains the estimation of whole-farm P mass balance using a suitable model system. The subsequent chapters provide updated information on management aspects of livestock-farming and generation of multiple job opportunities, and also explore various aspects of livestock farming operational protocols like housing and management; nurture of rams, ewes and lambs, new born calves and heifers; care of buck, doe and kid- nutrition flushing; concept zero grazing-systems; disease control and management; integrated goat farming; and crop-livestock integration. Further, the book addresses crop-livestock integration; energy autonomy in cattle farming; value added biopharmaceuticals from cattle farming; CAPEX for cattle farming; concepts of cattle farming; detrimental effects of the industry; topographic and edaphic factors, and thermal stress on livestock growth and development; socioeconomic development; and water requirements for livestock. The book concludes with the most important issue in the field of agriculture and veterinary science: "Livestock Farming with Care," describing sustainable, eco-friendly livestock farming by highlighting issues like animal feed vs. human food; agricultural GDP vs livestock, and factors affecting the sustainability of livestock farming. Given its scope, this book is a valuable resource for researchers and students alike, and will also appeal to practitioners in the field of livestock.

Cephalopods (octopus, squid, cuttlefish) are among the most intelligent invertebrates, with highly developed nervous systems which provide excellent model systems for investigating basic questions in neuroscience. Within the last five years, many of the powerful techniques of molecular biology and electrophysiology have been applied to cephalopods, with exciting results. In 32 chapters, this book provides a comprehensive overview of the functioning of the cephalopod nervous system, from the cellular level to their complex sensory systems, locomotion, learning, and social behavior. It will be of interest to both vertebrate and invertebrate neurobiologists, and by anyone interested in the basic principles that control neural function.

We are surrounded by thousands of animals, alive and dead. They are an intimate and ever-present part of our human lives. As a society, we privilege veterinarians as experts on these animals: they are our educators and teachers in what they say, what they do, and the decisions that they make. Yet, within the field of education, there is little research on the curriculum, pedagogy, and experiences of veterinary school and students. What do veterinarians learn in veterinary school? How do their experiences during those four years shape their perceptions of animals? How do the structures, curriculum, and pedagogy of veterinary college create and influence these experiences? Learning Animals opens up this conversation through an exploration of the complicated, fascinating and often painful stories of a cohort of veterinary students as they make their four-year journey from matriculation through graduation. The book examines how the experiences of veterinary students shape how humans relate to animals, from public policy and decision-making about the environment and animals slaughtered for food, to the most personal decisions about euthanizing companion animals. The first full-length, critical, qualitative study of the perspectives of our primary teachers about animals, this will be a thought-provoking read for those in the fields of both educational research and veterinary education.

Biology of Stress in Fish: Fish Physiology provides a general understanding on the topic of stress biology, including most of the recent advances in the field. The book starts with a general discussion of stress, providing answers to issues such as its definition, the nature of the physiological stress response, and the factors that affect the stress response. It also considers the biotic and abiotic factors that cause variation in the stress response, how the stress response is generated and controlled, its effect on physiological and organismic function and performance, and applied assessment of stress, animal welfare, and stress as related to model species.

Truly international, this extensive text combines the efforts of eight laboratories from seven countries in investigating the study of problems of manipulation, orienting, and navigating in humans and animals. The novel, multidisciplinary approach places the study of multisensory control of movement in a three-dimensional frame, with reference to computer models and neuronal mechanisms. Of interest to researchers, clinicians, and advanced students in neuroscience, psychology, and neurology, the text also has important implications for researchers in biomedical engineering and robotics.

The common fruit fly - Drosophila melanogaster - has been the subject of genetics research since the early twentieth century. The complete genomic sequence of Drosophila was published in 2000 and it is still the model organism par excellence for the experimental study of biological phenomena and processes. It is also by far the best model for studying gene function in mammals, including humans. Presenting state-of-the-art studies on the behaviour of Drosophila, this volume discusses normal and pathological models of neurobehavioral disorders and encompasses the specialised methods that have been used, from anatomical, histological, immunohistological and neurophysiological to genomic, genetic and behavioural assays. A comprehensive and thorough reference, this volume is a valuable resource for students and researchers alike across several disciplines of life sciences, including behavioral genetics, neurogenetics, behavioral neuroscience, molecular biology, evolutionary biology and population biology.

We are surrounded by thousands of animals, alive and dead. They are an intimate and ever-present part of our human lives. As a society, we privilege veterinarians as experts on these animals: they are our educators and teachers in what they say, what they do, and the decisions that they make. Yet, within the field of education, there is little research on the curriculum, pedagogy, and experiences of veterinary school and students. What do veterinarians learn in veterinary school? How do their experiences during those four years shape their perceptions of animals? How do the structures, curriculum, and pedagogy of veterinary college create and influence these experiences? Learning Animals opens up this conversation through an exploration of the complicated, fascinating and often painful stories of a cohort of veterinary students as they make their four-year journey from matriculation through graduation. The book examines how the experiences of veterinary students shape how humans relate to animals, from public policy and decision-making about the environment and animals slaughtered for food, to the most personal decisions about euthanizing companion animals. The first full-length, critical, qualitative study of the perspectives of our primary teachers about animals, this will be a thought-provoking read for those in the fields of both educational research and veterinary education.

Addresses the common stressors and struggles of those in the veterinary profession with a focus on real life stories and academic research. Emphasizes practical ways to build a positive supportive culture within the profession, through self-care and building resilience. A 2018 study in the Journal of the American Veterinary Medical Association gathered more than three decades of data to show that veterinarians are up to 3.5 times more likely to die by suicide than members of the general population. Burnout, compassion fatigue and depression are major issues for the veterinary profession, and this book will help vets address these issues head-on and give them tools to overcome them. Existing books on compassion fatigue tend to be more prescriptive. This book offers a more humanistic perspective, sharing real-life stories to show how we all struggle with similar issues and that there are things we can do to help. It connects readers to the fact that we all struggle, we all suffer, and there is a way to manage your professional life and thrive.

Biomechanics has a distinguished history extending at least to the 16th Century. However the later half oftbis century has seen an explosion ofthe field with it being viewed as affering exciting challenges for physical scientists and engineers interested in the life sciences, and wonderful opportunities for life scientists eager to collaborate with physical scientists and engineers and to render their scientific work more fundamental. That the field is now weil established and expanding is demonstrated by the formation of a World Committee for Biomechanics and the success and large participation in the 1st and 2nd World Congresses of Biomechanics, held respectively in San Diego in 1990 and in Amsterdam in 1994. With more than 1350 scientific papers delivered at the 2nd World Congress, either within symposia or oral or poster sessions, it would have been out of the question to try to produce comprehensive edited proceedings. Moreover, we are confident that most of the papers have been or will be published in one ofthe excellentjoumals covering the field. But of effort contributed by the plenary lecturers and the tutorial we thought that the large amount and keynote speakers of various symposia deserved tobe recognised in the form of a specific publication, thus also allowing those unable to attend the presentatiops . . tC\ sh?r~ in the findings. Furthermore, we feel that there is now a need to review aspects 'oftlie freld.

This monograph is the result of eight years of bibliographical and field research concerning several behavioural ecology aspects of the Palaearctic falcons. For a while, this book grew along with "The Lanner falcon" published in 2015 and revised in 2017. In both books the main aim was to provide a clear overview of the biology and ecology of these species. In fact in the last 20 years, the number of publications on falcons has grown tremendously and, in parallel, also those belonging to the so-called "grey literature". The number of people involved is also increased by including both academics and nature lovers. Many previously published books emphasized identification, and offered little insights on the behavioural and ecological aspects of the species. Very often, the research on behavioural ecology remains closed within the confines of academic community. By contrast, a multitude of basic data is scattered in countless articles published in local magazines. Many falcon species are easy to observe and study (such as kestrels) but others are more rare and localized. In order to understand the survival strategies adopted by this group of avian predators, it is necessary not to lose sight of the overall picture. This book tries to explain the different survival strategies by examining, through a few essential chapters, some crucial aspects for all species. The first chapter provides information on the genus Falco, its genetics, evolution and morphological peculiarities. The other chapters deal with reproductive strategies, competition, exploitation of resources, dispersal patterns, communication and sociality. One of the main objectives of this book is to produce an accessible but scholarly curated source of reference. By understanding the most common species, it is possible to provide a working framework for rarer, and especially threatened, falcon species.

Development is a complex and highly dynamic process involving the cross talk among genes, maternal effects and environmental circumstances. Widespread evidence from plant to animal species show that variation in developmental conditions can modulate life history trajectories and influence key traits, such as growth, reproduction, and senescence. These effects are not limited to a single generation but can also be passed on future generations. This book aims to bring together studies of early life effects from the fields of evolutionary biology, global change biology, and biomedicine to synthesise and improve current knowledge of the mechanisms involved, and how variation in early life conditions translates into Darwinian fitness outcomes. Relying on examples of organisms' responses to the ongoing and future environmental challenges of the Anthropocene, this book takes a novel approach to address the adaptive meaning of early life effects. The book has a broad scientific approach, targeting eco-evolutionary biologists, behavioural biologists, eco-physiologists, eco-toxicologists, as well as epidemiologists and biomedical scientists.

The International Symposium on Hearing is a highly-prestigious, triennial event where world-class scientists present and discuss the most recent advances in the field of hearing research in animals and humans. Presented papers range from basic to applied research, and are of interest neuroscientists, otolaryngologists, psychologists, and artificial intelligence researchers. Basic Aspects of Hearing: Physiology and Perception includes the best papers from the 2012 International Symposium on Hearing. Over 50 chapters focus on the relationship between auditory physiology, psychoacoustics, and computational modeling.

Fish Physiology: Physiology of Elasmobranch Fishes, Volume 34A is a useful reference for fish physiologists, biologists, ecologists, and conservation biologists. Following an increase in research on elasmobranchs due to the plight of sharks in today's oceans, this volume compares elasmobranchs to other groups of fish, highlights areas of interest for future research, and offers perspective on future problems. Covering measurements and lab-and-field based studies of large pelagic sharks, this volume is a natural addition to the renowned Fish Physiology series.