Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.

'David Christian's approach to understanding history can help all of us learn to prepare for the future' - Bill Gates A user's guide to the future: from the algorithms in DNA to why time is like a cocktail glass, interstellar migrations, transhumanism, the fate of the galaxy, and the last black hole... Every second of our lives - whether we're looking both ways before crossing the street, celebrating the birth of a baby, or moving to a new city - we must cope with an unknowable future. How do we do this? And how do we, like most living organisms, manage this impossible challenge quite well (at least most of the time)? David Christian, historian and bestselling author of Origin Story, is renowned for pioneering the emerging discipline of Big History, which surveys the whole of the past. But with Future Stories, he casts his sharp analytical eye forward, offering an introduction to the strange world of the future, and a guide to what we think we know about it at all scales, from the predictive mechanisms of single-celled organisms and tomato plants to the merging of colossal galaxies billions of years from now. Drawing together science, history and philosophy from a huge range of places and times, Christian explores how we prepare for uncertain futures, including the future of human evolution, artificial intelligence, interstellar travel, and more. By linking the study of the past much more closely to the study of the future, we can begin to imagine what the world will look like in the next hundred years and consider solutions to the biggest challenges facing us all.

Wild plants are not only beautiful, but they can also be an affordable and sustainable way to add flavor and nutrition to your diet. Edible Wild Plants for Beginners provides you with the essential information and guidance to begin foraging for edible wild plants and including them in your diet. Edible Wild Plants for Beginners provides profiles of common edible wild plants and includes information on dangerous look-alikes, the best time to harvest, where to find each type of wild plant, and how to cultivate your own garden. From natural remedies to delectable dishes and exotic cocktails, Edible Wild Plants for Beginners provides more than 95 ways for you to use these newfound ingredients. Edible Wild Plants for Beginners will help you explore the world of edible wild plants and teach you how to use them in your home and kitchen, with: More than 95 easy-to-follow edible wild plants recipes and remedies, including Amaranth Vegetable Curry, Pickled Jerusalem Artichokes, Chamomile Cookies, and a Purslane Martini Tips for foraging, harvesting, and cultivating edible wild plants Techniques for serving, preserving, and cooking with edible wild plants 31 edible wild plant profiles, including descriptions, distinguishing features, preparation and collection tips, and common uses 10 simple steps to making tinctures A guide to identifying edible wild plants and avoiding common poisonous plants With Edible Wild Plants for Beginners, you'll be able to start living sustainably, saving money, and adding variety to your diet the way nature intended.

'Gow reinvents what it means to be a guardian of the countryside.'-Guardian 'This authentic, impassioned manifesto-cum-memoir will hopefully have a major impact on what is likely to be a long-running controversy.'-The Spectator 'Gow has a fire in his belly. We need more like him.'-BBC Wildlife Magazine A Waterstones Best Nature Writing Book of 2020 'Bringing Back the Beaver is a hilarious, eccentric and magnificent account of a struggle . . . to reintroduce a species crucial to the health of our ecosystems.'-George Monbiot Bringing Back the Beaver is farmer-turned-ecologist Derek Gow's inspirational and often riotously funny first-hand account of how the movement to rewild beavers into the British landscape became the single most dramatic and subversive nature conservation act of the modern era. Since the early 1990s - in the face of outright opposition from government, landowning elites and even some conservation professionals - Gow has imported, quarantined and assisted the reestablishment of beavers in waterways across England and Scotland. With a foreword by bestselling author of Wilding, Isabella Tree, Bringing Back the Beaver makes a passionate case as to why the return of one of nature's great problem solvers will be critical as part of a sustainable fix for the UK's growing flooding problems, whilst ensuring the creation of essential landscapes that enable the broadest spectrum of Britain's wildlife to thrive. 'It is wonderful to see that beavers are now officially back on the list of native species, having been absent for so long . . . far too long!'-Dame Judi Dench

From a leading crisis management expert, a breakthrough book about performance under pressure that will change the way you think about stress Upshift 1. a movement of a variable to a higher level e.g. of performance, growth, frequency. When we experience too much stress, we often feel like shutting down and escaping the source. Neurologists call this 'downshifting', where your thinking shifts from the cognitive and creative areas in the brain to the domains associated with survival. But with too little stress, we become disengaged and apathetic. So what happens in the middle zone - when we experience what psychologists call positive stress - and how can we best make use of it? In Upshift, international thought leader Ben Ramalingam takes readers on an epic journey from early humans' survival of the ice age to present times in our inescapable, pernicious and ever-shifting digital landscape. You will hear remarkable stories from a vast range of backgrounds, including scientists, gamers, performers and artists, athletes and health professionals and everyday people, all of whom carved new routes around perceived barriers using their powers to upshift. Whether discussing how city commuters navigate train cancellations to how astronauts deal with life-threatening incidents, Ramalingam presents a fascinating argument that we all have the power to innovate, whether or not we identify ourselves as creative or extraordinary. In a runaway world that is an engine for perpetual crisis, Upshift is not only an essential toolkit for survival, it is a roadmap for positive, and potentially life-changing transformation and influence. You don't have to shut down - you can upshift.

Introduces basic principles and mechanisms, covers new developments, and provides a different view of the main facets of bioelectrosynthesis Bioelectrosynthesis represents a promising approach for storing renewable energy or producing target chemicals in an energy-sustainable and low-cost way. This timely and important book systemically introduces the hot issues surrounding bioelectrosynthesis, including potential value-added products via bioelectrochemical system, reactor development of bioelectrosynthesis, and microbial biology on biofilm communities and metabolism pathways. It presents readers with unique viewpoints on basic principles and mechanisms along with new developments on reactor and microbial ecology. Beginning with a principle and products overview of bioelectrosynthesis, Bioelectrosynthesis: Principles and Technologies for Value-Added Products goes on to offer in-depth sections on: biogas production and upgrading technology via bioelectrolysis; organic synthesis on cathodes; chemical products and nitrogen recovery; external electron transfer and electrode material promotion; and the microbiology of bioelectrosynthesis. Topics covered include: hydrogen production from waste stream with microbial electrolysis cell; microbial electrolysis cell; inorganic compound synthesis in bioelectrochemical system; microbial growth, ecological, and metabolic characteristics in bioelectrosynthesis systems; microbial metabolism kinetics and interactions in bioelectrosynthesis system; and more. * Comprehensively covers all of the key issues of biolelectrosynthesis * Features contributions from top experts in the field * Examines the conversion of organic wastes to methane via electromethanogenesis; methane production at biocathodes; extracellular electron transport of electroactive biofilm; and more Bioelectrosynthesis: Principles and Technologies for Value-Added Products will appeal to chemists, electrochemists, environmental chemists, water chemists, microbiologists, biochemists, and graduate students involved in the field.

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure-function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting "What We Don't Know," introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Sunday Times Bestseller 'A paradigm-smashing chronicle of joyous entanglement' Charles Foster Waterstones Non-Fiction Book of the Month (September) Are trees social beings? How do trees live? Do they feel pain or have awareness of their surroundings? In The Hidden Life of Trees Peter Wohlleben makes the case that the forest is a social network. He draws on groundbreaking scientific discoveries to describe how trees are like human families: tree parents live together with their children, communicate with them, support them as they grow, share nutrients with those who are sick or struggling, and even warn each other of impending dangers. Wohlleben also shares his deep love of woods and forests, explaining the amazing processes of life, death and regeneration he has observed in his woodland. A walk in the woods will never be the same again.

With a new afterword, Why You Are Here: A speech on the opening of the COP26 climate summit As a young man, I felt I was out there in the wild, experiencing the untouched natural world - but it was an illusion. The tragedy of our time has been happening all around us, barely noticeable from day to day - the loss of our planet's wild places, its biodiversity. I have been witness to this decline. A Life on Our Planet contains my witness statement, and my vision for the future - the story of how we came to make this, our greatest mistake, and how, if we act now, we can yet put it right. We have the opportunity to create the perfect home for ourselves and restore the wonderful world we inherited. All we need is the will do so.

Provides a comprehensive systematic review of the African proboscidean fossil record Includes a summary of taxonomy, geochronology, biogeography and morphology Documents major faunal events including those associated with hominin origins Synthesizes new data from genomic, isotopic and microware analyses Emphasizes the role of elephants in ecosystems and the importance of conservation

The Sunday Times bestseller *Shortlisted for the Wainwright Prize* A New Statesman and Spectator Book of the Year 'This book calls for nothing less than a revolution in the future of food' Kate Raworth From the bestselling author of Feral, a breathtaking first glimpse of a new future for food and for humanity Farming is the world's greatest cause of environmental destruction - and the one we are least prepared to talk about. We criticise urban sprawl, but farming sprawls across thirty times as much land. We have ploughed, fenced and grazed great tracts of the planet, felling forests, killing wildlife, and poisoning rivers and oceans to feed ourselves. Yet millions still go hungry. Now the food system itself is beginning to falter. But, as George Monbiot shows us in this brilliant, bracingly original new book, we can resolve the biggest of our dilemmas and feed the world without devouring the planet. Regenesis is a breathtaking vision of a new future for food and for humanity. Drawing on astonishing advances in soil ecology, Monbiot reveals how our changing understanding of the world beneath our feet could allow us to grow more food with less farming. He meets the people who are unlocking these methods, from the fruit and vegetable grower revolutionising our understanding of fertility; through breeders of perennial grains, liberating the land from ploughs and poisons; to the scientists pioneering new ways to grow protein and fat. Together, they show how the tiniest life forms could help us make peace with the planet, restore its living systems, and replace the age of extinction with an age of regenesis.

FROM THE AUTHOR OF THE SUNDAY TIMES BESTSELLER,THE HIDDEN LIFE OF TREES 'A simultaneously stimulating and soothing blend of nature writing and science ... Strongly encourages tree hugging for our own, human sake' Guardian Summer Reads 2021 A powerful return to the forest, where trees have heartbeats and roots are like brains that extend underground. Where the colour green calms us, and the forest sharpens our senses. In The Heartbeat of Trees, renowned forester Peter Wohlleben draws on new scientific discoveries to show how humans are deeply connected to the natural world. In an era of climate change, many of us fear we've lost our connection to nature, but Wohlleben is convinced that age-old ties linking humans to the forest remain alive and intact. We just have to know where to look. Drawing on science and cutting-edge research, The Heartbeat of Trees reveals the profound interactions humans can have with nature, exploring: the language of the forest the consciousness of plants and the eroding boundary between flora and fauna A perfect book to take with you into the woods, The Heartbeat of Trees shares how to see, feel, smell, hear, and even taste the forest. Peter Wohlleben, renowned for his ability to write about trees in an engaging and moving way, reveals a wondrous cosmos where humans are a part of nature, and where conservation and environmental activism is not just about saving trees, it's about saving ourselves, too.

'A brilliant book [that] shows a way out of the destructive trap of Anthropocentric arrogance.' Vandana Shiva, from the Foreword Biocivilisations is a fascinating, original and important exploration into how complex civilisations existed on Earth long before humans. What is life? This is arguably the most important question in all of science. Many scientists believe life can be reduced to ‘mechanistic’ factors, such as genes and information codes. Everything can be sequenced and explained. But in a world as rich and complex as this one, can such an assertion really be true? A growing army of scientists, philosophers and artists do not share this mechanistic vision for the science of life. The gene metaphor is not only too simplistic but also misleading. If there is a way to reduce life to a single principle, how does that principle acknowledge the creativity of life that turns both genetic and information determinism on their heads? Biocivilisations is a groundbreaking book exploring the mysteries of life and its deep uncertainty. Dr Predrag Slijep�ević turns anthropocentric scientific thinking on its head, showing how the humble bacteria created the equivalent of cities and connected them with information highways, bringing our planet to life three thousand million years ago. He explains how bacteria, amoebas, plants, insects, birds, whales, elephants and countless other species not only preceded human beings but also demonstrate elements of complex civilisation – communication, agriculture, science, art, medicine and more – that we associate with human achievement. More than 99.99 percent of life on Earth has existed without humanity, and life will continue without humans long into the future. Biocivilisations is an important rethinking of the current scientific paradigm. It challenges us to reconsider the limited scope and time-window of our current ‘scientific revolution’ and to fundamentally reimagine what we call ‘life on Earth’.

Being Human is history made flesh. It will change the way you see the world. We are a wonder of evolution. Powerful yet dextrous, instinctive yet thoughtful, we are expert communicators and innovators. Our exceptional abilities have created the civilisation we know today. But we're also deeply flawed. Our bodies break, choke and fail, whether we're kings or peasants. Diseases thwart our boldest plans. Our psychological biases have been at the root of terrible decisions in both war and peacetime. This extraordinary contradiction is the essence of what it means to be human - the sum total of our frailties and our faculties. And history has played out in the balance between them. Now, for the first time, Lewis Dartnell tells our story through the lens of this unique, capricious and fragile nature. He explores how our biology has shaped our relationships, our societies, our economies and our wars, and how it continues to challenge and define our progress. Praise for Lewis Dartnell's Origins and The Knowledge: 'Stands comparison with Yuval Harari's Sapiens ... A thrilling piece of big history' Sunday Times on Origins 'The most inspiring book I've read for a long time' Independent on The Knowledge

World-renowned biohacker and bestselling author Dave Asprey reveals how to maximize your well-being with the minimum effort, by taking control of your body's operating system. If you want to lose weight, boost your energy, or sharpen your mind, there are shelves of books offering myriad styles of advice. If you want to build up your strength and cardio fitness, there are plenty of gyms and trainers ready to offer you their guidance. What all of these resources have in common is they offer you a bad deal: a lot of effort for a little payoff. Dave Asprey has found a better way. In Smarter Not Harder, the proven master of biohacking exposes the surprising secrets of your body's operating system, or its "MeatOS." That system is naturally designed to be lazy, which is why sweaty exercise routines and rigid diets produce such limited effects. Dave shows us how to hack the MeatOS and make it do what we want it to do, turning it from obstacle into ally. The key to achieving optimum wellness, he reveals, isn't about doing more, it's about doing less-exercising and eating smarter, not harder, and making the body's built in laziness work for you. Smarter Not Harder is not a diet nor a fitness plan. It is a system of targeted biohacks aimed at upgrading your metabolic, neurological, and epigenetic systems. Packed with practical, accessible information on better eating; smart workouts that give you more strength and energy in less time; and strategic therapies to reduce stress and boost resilience-Smarter Not Harder will show you how to achieve lasting health in less time.

'Powerfully argued... Fascinating and pacy' Sunday Times, Book of the Week 'Superbly written... sure to please readers of Yuval Noah Harari or Rutger Bregman' The Times 'Full of amazing facts' Observer 'A humbling story for humankind' Spectator Challenges some of the greatest cliches about colonialism... A revelation' SATHNAM SANGHERA 'Thrilling and eye-opening' LEWIS DARTNELL 'Science and history at its best' MARK HONIGSBAUM 'Unpicks everything we thought we knew... Mind blowing' CAL FLYN In this revelatory book, Dr Jonathan Kennedy argues that germs have shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam. How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? And why did the Industrial Revolution lead to the birth of the modern welfare state? The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are. Indeed, the only reason humans don't lay eggs is that a virus long ago inserted itself into our DNA, and there are as many bacteria in your body as there are human cells. We have been thinking about the survival of the fittest all wrong: evolution is not simply about human strength and intelligence, but about how we live and thrive in a world dominated by microbes. By exploring the startling intimacy of our relationship with infectious diseases, Kennedy shows how they have been responsible for some of the seismic revolutions of the past 50,000 years. Provocative and brimming with insight, Pathogenesis transforms our understanding of the human story, revealing how the crisis of a pandemic can offer vital opportunities for change.

The world's most comprehensive reference for clinical and forensic toxicologists has once more been extensively updated: 2,000 data sets have been added for a total of 10,430 spectra of potentially harmful substances, including 7,800 from metabolites. In two hardbound volumes, the printed atlas contains a comprehensive listing of full reference mass spectra in order or molecular mass with the structural formula, exact mass, GC retention times and other experimental data that are relevant to the analytical toxicologist. To aid in compound identification, all substances are classified according to their toxicological categories. In addition, volume 1 contains an overview on experimental methods, plus a compound index by name. An electronic database for use with all major mass spectrometers is also available. For details, please visit www.wiley.com/go/databases.

The evolution of a classic The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focuses on genetic analysis, quantitative problem solving, and experimentation continue in this new edition while incorporating robust updates to the science. Introduction to Genetic Analysis is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

Derived from the classic text originated by Lubert Stryer and continued by John Tymoczko and Jeremy Berg, Biochemistry: A Short Course focuses on the major topics taught in a one-semester biochemistry course. With its brief chapters and relevant examples, this thoroughly updated new edition helps students see the connections between the biochemistry they are studying and their own lives. Biochemistry: A Short Course is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for chemistry students. Achieve includes an interactive eBook as well as our renowned assessments and innovative, interactive Metabolic Map. Students will be able to focus their study with adaptive quizzing and more clearly see the relevance of chemistry through case studies. Instructor resources, including tools for active learning, are all housed in this exciting new platform.

This is the first book to provide a comprehensive overview of the field of artificial nucleic acids. Covering a tremendous amount of literature on the chemistry, biology, and structure of artificial nucleic acids, it will constitute an invaluable source of information for the specialist and for young researchers interested in starting a career in this fascinating field of research alike.
This book combines the contributions of many of the major players in this research field, and covers the synthesis of sugar-, base- and backbone-modified nucleic acids, their structural characteristics studied by X-ray crystallography, and NMR in solution as well as their chemical and biological properties.

A value pack compiled for Oxford Brookes University Genetics Students.