We are becoming increasingly aware of the overwhelming pollution of our limited water resources on this planet. And while many contaminants originate from Mother Earth, most water pollution comes as a direct result of anthropogenic activities. This problem has become so immense that it threatens the future of all humanity. If effective measures to reduce and/or remediate water pollution and its sources are not found, it is estimated by UN that 2.7 billion people will face water shortage by 2025 as opposed to 1.2 billion people who do not have access to clean drinking water now. Therefore, development of novel green technologies to address this major problem represents a priority of the highest importance. This book discusses green chemistry and other novel solutions to the water pollution problems which includes some interesting applications of nanoparticles. Novel Solutions to Water Pollution is a useful and informative text for those engaged in issues of water quality and water pollution remediation at operational, administrative, academic, or regulatory levels.

The history of life is a nearly four billion year old story of transformative change. This change ranges from dramatic macroscopic innovations such as the evolution of wings or eyes, to a myriad of molecular changes that form the basis of macroscopic innovations. We are familiar with many examples of innovations (qualitatively new phenotypes that can provide a critical advantage) but have no systematic understanding of the principles that allow organisms to innovate. This book proposes several such principles as the basis of a theory of innovation, integrating recent knowledge about complex molecular phenotypes with more traditional Darwinian thinking. Central to the book are genotype networks: vast sets of connected genotypes that exist in metabolism and regulatory circuitry, as well as in protein and RNA molecules. The theory can successfully unify innovations that occur at different levels of organization. It captures known features of biological innovation, including the fact that many innovations occur multiple times independently, and that they combine existing parts of a system to new purposes. It also argues that environmental change is important to create biological systems that are both complex and robust, and shows how such robustness can facilitate innovation. Beyond that, the theory can reconcile neutralism and selectionism, as well as explain the role of phenotypic plasticity, gene duplication, recombination, and cryptic variation in innovation. Finally, its principles can be applied to technological innovation, and thus open to human engineering endeavours the powerful principles that have allowed life's spectacular success.

In this book, Chris Eliasmith presents a new approach to understanding the neural implementation of cognition in a way that is centrally driven by biological considerations. He calls the general architecture that results from the application of this approach the Semantic Pointer Architecture (SPA), based on the Semantic Pointer Hypothesis. According to this hypothesis, higher-level cognitive functions in biological systems are made possible by semantic pointers. These pointers are neural representations that carry partial semantic content and can be built up into the complex representational structures necessary to support cognition. The SPA architecture demonstrates how neural systems generate, compose, and control the flow of semantics pointers. Eliasmith describes in detail the theory and empirical evidence supporting the SPA, and presents several examples of its application to cognitive modeling, covering the generation of semantic pointers from visual data, the application of semantic pointers for motor control, and most important, the use of semantic pointers for representation of language-like structures, cognitive control, syntactic generalization, learning of new cognitive strategies, and language-based reasoning. He agues that the SPA provides an alternative to the dominant paradigms in cognitive science, including symbolicism, connectionism, and dynamicism.

Rethinking Thought takes readers into the minds of 30 creative thinkers to show how greatly the experience of thought can vary. It is dedicated to anyone who has ever been told, "You're not thinking!", because his or her way of thinking differs so much from a spouse's, employer's, or teacher's. The book focuses on individual experiences with visual mental images and verbal language that are used in planning, problem-solving, reflecting, remembering, and forging new ideas. It approaches the question of what thinking is by analyzing variations in the way thinking feels. Written by neuroscientist-turned-literary scholar Laura Otis, Rethinking Thought juxtaposes creative thinkers' insights with recent neuroscientific discoveries about visual mental imagery, verbal language, and thought. Presenting the results of new, interview-based research, it offers verbal portraits of novelist Salman Rushdie, engineer Temple Grandin, American Poet Laureate Natasha Trethewey, and Nobel prize-winning biologist Elizabeth Blackburn. It also depicts the unique mental worlds of two award-winning painters, a flamenco dancer, a game designer, a cartoonist, a lawyer-novelist, a theoretical physicist, and a creator of multi-agent software. Treating scientists and artists with equal respect, it creates a dialogue in which neuroscientific findings and the introspections of creative thinkers engage each other as equal partners. The interviews presented in this book indicate that many creative people enter fields requiring skills that don't come naturally. Instead, they choose professions that demand the hardest work and the greatest mental growth. Instead of classifying people as "visual" or "verbal," educators and managers need to consider how thinkers combine visual and verbal skills and how those abilities can be further developed. By showing how greatly individual experiences of thought can vary, this book aims to help readers in all professions better understand and respect the diverse people with whom they work.

Consumers, regulators, and the food industry increasingly require that foods comply not only with label descriptions of food content, but also with information regarding the food's origin. For example, the wine industry has a long history of labeling wines based on varietal, regional, or age (vintage)-related properties. However, regulatory agencies are now beginning to require methods to confirm this label information. Food retailers are also facing voluntary or mandatory labeling requirements that will indicate regional or country-of-origin, species and/or varietal information. As a result, development of reliable analytical methods to confirm the authenticity of the label information is needed. This book presents the latest research on food and wine authentication. The chapters are authored by leading international scientists whose research focuses on the development and application of analytical methodologies used for the authentication of food and beverages.

The human pathogens Neisseria meningitidis and Neisseria gonorrhoeae are exquisitely adapted to life within the human mucosa, their only natural niche. N. meningitidis is the causative agent of rapidly transmissible meningitis and septic shock. Vaccines developed to control this pathogen can be rendered ineffective by the pathogen's ability to undergo antigenic variation. In contrast, there are no current vaccination prospects for N. gonorrhoeae, the causative agent of sexually transmitted gonorrhoea. Historically, infections caused by N. gonorrhoeae were treated with antibiotics. However, the recent advent of new strains with resistance to all known antibiotics is causing such treatment regimes to fail, necessitating the need for new and more effective control strategies. In this book, leading Neisseria authorities review the most important research on pathogenic Neisseria to provide a timely overview of the field. The topics covered include: the link between pathogenesis and important metabolic pathways * vaccine development * antibiotic resistance * transcriptomics of regulatory networks * regulatory small RNAs * interactions with neutrophils * advances in humanized mouse models. An essential guide for research scientists, advanced students, clinicians, and other professionals working with Neisseria, the book is a recommended text for all microbiology libraries.

Measuring metabolic rates is central to important questions in many areas of scientific research. Unfortunately these measurements are anything but straightforward, and numerous pitfalls await the novice and even the experienced investigator.
Measuring Metabolic Rates de-mystifies the field, explaining every common variation of metabolic rate measurement, from century-old manometric methods through ingenious syringe-based techniques, direct calorimetry, aquatic respirometry, stable-isotope metabolic measurement and every type of flow-through respirometry. Each variation is described in enough detail to allow it to be applied in practice. Background information on different analyzer and equipment types allows users to choose the best instruments for their application. Respirometry equations - normally a topic of terror and confusion to researchers - are derived and described in enough detail to make their selection and use effortless.
Vital topics such as manual and automated baselining, implementing multi-animal systems, and the correct analysis and presentation of metabolic data are covered in enough detail to turn a respirometry neophyte into a hardened metabolic warrior, ready to take on the task of publication in peer-reviewed journals.

Rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. This promises to offer unprecedented insights into the fundamental biological nature of ourselves and our species: where we came from, how we begin our lives, how we develop and grow, how we interact with our environment, how we get sick, how we get well, and how we age. Personal genomics is an essential component of the inevitable transition towards personalized health and medicine. As the medical establishment begins to explore and evaluate the role of personal genomics in health and medicine, both clinicians and patients alike will gain from becoming well versed in both the power and the pitfalls of personal genomic information. Furthermore, it is likely that all students of the biomedical sciences will soon be required to gain crucial understanding in the emerging field of personal genomics. Exploring Personal Genomics provides a novel, inquiry-based approach to the understanding and interpretation of the practical, medical, physiological, and societal aspects of personal genomic information. The material is presented in two parts: the first provides readers of all backgrounds with a fundamental understanding of the biology of human genomes, information on how to obtain and understand digital representations of personal genomic data, tools and techniques for exploring the personal genomics of ancestry and genealogy, discovery and interpretation of genetic trait associations, and the role of personal genomics in drug response. The second part offers more advanced readers an understanding of the science, tools, and techniques for investigating interactions between a personal genome and the environment, connecting DNA to physiology, and assessing rare variants and structural variation. This book aims to support undergraduate and graduate studies in medicine, genetics, molecular biology, and bioinformatics. Additionally, the design of the content is such that medical practitioners, professionals working in the biomedical sciences or related fields, and motivated lay individuals interested in exploring their personal genetic data should find it relevant and approachable.

Although the problem of controlling the spread of exotic invasive plant and animal species in the United States has been recognized for quite some time, it has been lacking an adequate legislative mandate, public awareness, and sufficient funding to meet the challenge. This ACS Symposium Series title showcases the many diverse efforts being made to control invasive species at the federal, state, and local levels. It recognizes the global extent of the problem and compares the methods used in other countries with those of the U.S., and includes recommendations of how best to proceed from here.

Observing Bioethics examines the history of bioethics as a discipline related not only to modern biology, medicine, and biotechnology, but also to the core values and beliefs of American society and its courts, legislatures, and media. The book is written from the perspective of two social scientists--a sociologist of medicine(Renee C. Fox) and a historian of medicine (Judith P. Swazey)--who have participated in bioethics since the emergence of this multidisciplinary field more than 30 years ago.
Fox and Swazey draw on first-hand observations and experiences in a variety of American bioethical settings; face-to-face interviews with first- and second-generation figures in the genesis and early unfolding of bioethics; a detailed examination of the theatrical media coverage of what was considered to be a banner event in the annals of bioethics (the creation and birth of the cloned sheep, Dolly); case studies of how bioethics has internationally developed; and a large corpus of primary documents and secondary source materials.
While recognizing the intellectual, moral, and sociological importance of American bioethics, Fox and Swazey are critical of its characteristics. Foremost among these are what they identify as the problems of thinking socially, culturally, and internationally in American bioethics; the 'tenuous interdisciplinarity' of the field; and the troubling extent to which the 'culture wars' have penetrated bioethics.
This book will appeal to a wide range of doctors, scientists, and academics who are involved in the history and sociology of bioethics.

In recent decades there has been an explosion in work in the social and physical sciences describing the similarities between human and nonhuman as well as human and non-animal thinking. This work has explicitly decentered the brain as the sole, self-contained space of thought, and it has found thinking to be an activity that operates not only across bodies but also across bodily or cellular membranes, as well as multifaceted organic and inorganic environments. For example, researchers have looked at the replication and spread of slime molds (playfully asking what would happen if they colonized the earth) to suggest that they exhibit 'smart behavior' in the way they move as a potential way of considering the spread of disease across the globe. Other scholars have applied this model of non-human thought to the reach of data mining and global surveillance. In The Biopolitics of Alphabets and Embryos, Ruth Miller argues that these types of phenomena are also useful models for thinking about the growth, reproduction, and spread of political thought and democratic processes. Giving slime, data and unbounded entities their political dues, Miller stresses their thinking power and political significance and thus challenges the anthropocentrism of mainstream democratic theories. Miller emphasizes the non-human as highly organized, systemic and productive of democratic growth and replication. She examines developments such as global surveillance, embryonic stem cell research, and cloning, which have been characterized as threats to the privacy, dignity, and integrity of the rational, maximizing and freedom-loving democratic citizen. By shifting her level of analysis from the politics of self-determining subjects to the realm of material environments and information systems, Miller asks what might happen if these alternative, nonhuman thought processes become the normative thought processes of democratic engagement.

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, measured by major advances, the greatest decade in the history of brain studies was mid-twentieth century, especially the 1950s. The first to focus on worldwide contributions in this period, the book ranges through dozens of astonishing discoveries at all levels of the brain, from DNA (Watson and Crick), through growth factors (Hamburger and Levi-Montalcini), excitability (Hodgkin and Huxley), synapses (Katz and Eccles), dopamine and Parkinson's (Carlsson), visual processing (Hartline and Kuffler), the cortical column (Mountcastle), reticular activating system (Morruzzi and Magoun) and REM sleep (Aserinsky), to stress (Selye), learning (Hebb) and memory (HM and Milner). The clinical fields are also covered, from Cushing and Penfield, psychosurgery and brain energy metabolism (Kety), to most of the major psychoactive drugs in use today (beginning with Delay and Deniker), and much more.
The material has been the basis for a highly successful advanced undergraduate and graduate course at Yale, with the classic papers organized and accessible on the web. There is interest for a wide range of readers, academic, and lay because there is a focus on the creative process itself, on understanding how the combination of unique personalities, innovative hypotheses, and new methods led to the advances. Insight is given into this process through describing the struggles between male and female, student and mentor, academic and private sector, and the roles of chance and persistence. The book thus provides a new multidisciplinary understanding of the revolution that created the modern field of neuroscience and set the bar for judging current and future advances.

The History of British Birds reviews our knowledge of avifaunal history over the last 15,000 years, setting it in its wider historical and European context. The authors, one an ornithologist, the other an archaeologist, integrate a wealth of archaeological data to illuminate and enliven the story, indicating the extent to which climatic, agricultural, and social changes have affected the avifauna. They discuss its present balance, as well as predicting possible future changes.
It is a popular misconception that bird bones are rarely preserved (compared with mammals), and cannot be reliably identified when they are found. The book explores both these contentions, armed with a database of 9,000 records of birds that have been identified on archaeolgical sites. Most are in England, but sites elsewhere in Great Britian, Ireland, the Isle of Man and the Channel Isles are included.
Britain's most numerous bird is also the most widespread in the archaeological record, but some of the more charismatic species also have a rich historical pedigree. For example, we can say quite a lot about the history of the Crane, Red Kite, White-tailed Eagle and great Auk. The history of many introduced domestic species can also be illuminated. Even so, there remain uncertainties, posed by difficulties of dating or identification, the vagaries of the archaeological record or the ecological specialities of the birds themselves. These issues are highlighted, thus posing research questions for others to answer.
And the commonest British bird, then and now? Buy the book and read on...

The Arctic Tundra and adjacent Boreal Forest or Taiga support the most cold-adapted flora and fauna on Earth. The evolutionary capacity of both plants and animals to adapt to these thermally limiting conditions has always attracted biological investigation and is a central theme of this book. How the polar biota will adapt to a warmer world is creating significant and renewed interest in this habitat. The Arctic has always been subject to climatic fluctuation and the polar biota has successfully adapted to these changes throughout its evolutionary history. Whether or not climatic warming will allow the Boreal Forest to advance onto the treeless Tundra is one of the most tantalizing questions that can be asked today in relation to terrestrial polar biology. Tundra-Taiga Biology provides a circum-polar perspective of adaptation to low temperatures and short growing seasons, together with a history of climatic variation as it has affected the evolution of terrestrial life in the Tundra and the adjacent forested Taiga. It will appeal to researchers new to the field and to the many students, professional ecologists and conservation practitioners requiring a concise but authoritative overview of the biome. Its accessibility also makes it suitable for undergraduate and graduate students taking courses in tundra, taiga, and arctic ecology.

The third edition of The Basics of Bioethics continues to provide a balanced and systematic ethical framework to help students analyze a wide range of controversial topics in medicine, and consider ethical systems from various religious and secular traditions. The Basics of Bioethics covers the "Principalist" approach and identifies principles that are believed to make behavior morally right or wrong. It showcases alternative ethical approaches to health care decision making by presenting Hippocratic ethics as only one among many alternative ethical approaches to health care decision-making. The Basics of Bioethics offers case studies, diagrams, and other learning aids for an accessible presentation. Plus, it contains an all-encompassing ethics chart that shows the major questions in ethics and all of the major answers to these questions.

Because of their vital role in the emergence of humanity, tools and their uses have been the focus of considerable worldwide study. This volume brings together international research on the use of tools among primates and both prehistoric and modern humans. The book represents leading work being done by specialists in anatomy, neurobiology, prehistory, ethnology, and primatology. Whether composed of stone, wood, or metal, tools are a prolongation of the arm that acquire precision through direction by the brain. The same movement, for example, may have been practiced by apes and humans, but the resulting action varies according to the extended use of the tool. It is therefore necessary, as the contributors here make clear, to understand the origin of tools, and also to describe the techniques involved in their manipulation, and the possible uses of unknown implements. Comparison of the techniques of chimpanzees with those of prehistoric and modern peoples has made it possible to appreciate the common aspects and to identify the differences. The transmission of ability has also been studied in the various relevant societies: chimpanzees in their natural habitat and in captivity, hunter-gatherers, and workmen in prehistoric and in modern times. In drawing together much valuable research, this work will be an important and timely resource for social and behavioral psychologists, anthropologists, paleontologists, and animal behaviorists.

This book is about pleasure. It's also about pain. Most important, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential.

We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.

In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

This manual provides an easy guide to pain management for the veterinary practitioner. Beginning with pain terminology, it goes on to describe to physiology of pain, management strategies, various drugs and techniques, and the management of specific conditions and procedures. Strategies for the treatment of pain are comprehensively reviewed, with an overview of the mechanisms by which pain is perceived and the principles of pain management. The drugs currently used in the treatment of acute and chronic pain are discussed as well as the specific techniques that can be used to control intra- and post operative pain in dogs and cats. The book covers a broad range of information on specific aspects of pain management from analgesic techniques to management of chronic pain to pain perception. Published by Teton New Media USA and distributed by CRC Press outside of North America.

The Shape of Thought: How Mental Adaptations Evolve presents a road map for an evolutionary psychology of the twenty-first century. It brings together theory from biology and cognitive science to show how the brain can be composed of specialized adaptations, and yet also an organ of plasticity. Although mental adaptations have typically been seen as monolithic, hard-wired components frozen in the evolutionary past, The Shape of Thought presents a new view of mental adaptations as diverse and variable, with distinct functions and evolutionary histories that shape how they develop, what information they use, and what they do with that information. The book describes how advances in evolutionary developmental biology can be applied to the brain by focusing on the design of the developmental systems that build it. Crucially, developmental systems can be plastic, designed by the process of natural selection to build adaptive phenotypes using the rich information available in our social and physical environments. This approach bridges the long-standing divide between "nativist" approaches to development, based on innateness, and "empiricist" approaches, based on learning. It shows how a view of humans as a flexible, culturally-dependent species is compatible with a complexly specialized brain, and how the nature of our flexibility can be better understood by confronting the evolved design of the organ on which that flexibility depends.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

Exam Board: OCR Level: A level Subject: Science / Biology First teaching: September 2015 First exams: June 2017 An ActiveBook is included with every Student Book, giving your students easy online access to the content in the Student Book. They can make it their own with notes, highlights and links to their wider reading. Perfect for supporting work and revision activities. Student Book 1 supports a standalone AS course and provides the first year of a two-year A level course; Student Books 1 and 2 together support the full A level course. A cumulative approach to learning constantly builds on what has previously been taught. The chapter openers highlight prior learning requirements and link to future learning. The required maths skills are highlighted at the start of each chapter providing opportunities for students to check understanding and remedy gaps. Bigger spreads require students to read real-life material that's relevant to the course and use knowledge in new contexts. Accompanying questions require students to analyse how scientists write, think critically and consider issues. Preparing for your exams sections highlight the key differences between preparing for an AS and full A level exam. Practice question spreads provide opportunities for students to regularly check their understanding using questions written in the style of the new exams from day one.

Flora of North America, Volume 3, provides information on many of the most familiar wildflowers and trees in North America. Included are treatments of the buttercup family (Ranunculacaeae), with such plants as delphiniums and columbines, and the poppy family (Papveraceae). Most of the important broadleaf tree species are covered, including the oaks (Fagaceae), elms (Ulmaceae), birches (Betulaceae), walnuts (Juglandaceae), plane trees (Plantanaceae), and magnolias (Magnoliaceae). Many striking families are covered, such as the dutchman's pipe family (Aristochiaceae), and the aquatic families Nymphaeceae (water lilies), and Melumbonaceae (lotus).

Identification keys, summaries of habitats and geographic ranges, distribution maps, pertinent synonymies, descriptions, chromosome numbers, phenological information, and other significant biological observations are given for each species. The treatments, written and reviewed by experts throughout the systematic botanical community, are based on original observations of herbarium specimens, and wherever possible, on living plants. These observations are supplemented by critical reviews of the literature.