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Books > Medicine > Nursing & ancillary services > Biomedical engineering

Polysaccharide-based Biomaterials - Delivery of Therapeutics and Biomedical Applications (Hardcover): Sougata Jana, Subrata... Polysaccharide-based Biomaterials - Delivery of Therapeutics and Biomedical Applications (Hardcover)
Sougata Jana, Subrata Jana, Abraham J. Domb
R6,732 Discovery Miles 67 320 Ships in 10 - 15 working days

Polysaccharides are natural, renewable materials that are biodegradable and biocompatible, making them ideal subjects for biomedical applications. This book focusses on the main polysaccharides, including but not limited to chitosan, cellulose, alginate, dextran, guar gum, gellan gum, pullulan, locust bean gum, pectin, xanthan gum, starch, hyaluronan and carrageenan, and their applications in drug delivery, imaging and tissue engineering. With contributions from around the world, the editors have pulled together a tightly curated set of chapters which showcase how polysaccharide-based materials are employed in a range of biomedical systems. The end result is a book in which the reader can gain a sound overview of this important class of material for biomedical applications, without scouring journal articles. Those working in materials science, biomedical and chemical engineering, and pharmaceutical technologies will find this a must-have reference.

Paediatric Rehabilitation Engineering - From Disability to Possibility (Paperback): Tom Chau, Jillian Fairley Paediatric Rehabilitation Engineering - From Disability to Possibility (Paperback)
Tom Chau, Jillian Fairley
R1,784 Discovery Miles 17 840 Ships in 12 - 17 working days

Innovations in paediatric rehabilitation engineering can serve as a springboard to education, psychosocial, social, physical and cognitive development for children and youth with disabilities. Instead of providing an overview of rehabilitation engineering, Paediatric Rehabilitation Engineering focuses on the uniqueness of the paediatric subspecialty via an international sampling of methods and techniques currently in use or in development. The book is divided into three complementary components. The first group of chapters is broadly concerned with connecting individuals to their environment and to the people around them. The second group revolves around paediatric technologies that compensate for compromised or missing function. The final group of chapters is about machines and environments which provide stimulating and interactive platforms for therapy and research. Topics include: Microswitch-based occupational, recreational and rehabilitation programs Emerging access technologies, like infrared thermal imaging and vocal cord vibration detection Communication technologies to enable children to communicate in a variety of everyday environments Accessible graphical user and Web-based interface design Postural and upper and lower extremity compensation, such as customized chairs and prostheses Global efforts in the area of robotics for autism research Virtual reality and other interfaces to mitigate motor, communication, and physical control difficulties Paedriatric rehabilitation engineering offers endless possibilities for future research with implications across the fields of physical and cognitive rehabilitation, medicine, computer science, and policy. It is the harmonizing of the expertise and energies of rehabilitation professionals such as teachers, families, paediatric rehabilitation engineers, and other stakeholders that will ensure that children are optimally supported as they embark on their journey from disability to possibility.

Regenerative Engineering (Paperback): Cato T. Laurencin, Yusuf Khan Regenerative Engineering (Paperback)
Cato T. Laurencin, Yusuf Khan
R1,678 Discovery Miles 16 780 Ships in 12 - 17 working days

Distinct from tissue engineering, which focuses primarily on the repair of tissues, regenerative engineering focuses on the regeneration of tissues: creating living, functional tissue that has the ability to replace organs that are dysfunctional. The challenge of working in an area like regenerative engineering lies, in part, in the breadth of information required to truly appreciate and begin to think about this field. Regenerative Engineering introduces the field through the presentation of fundamental concepts of cell biology, stem cell science, materials science, and cell-material interactions. It also focuses on specific organ and tissue types and presents up-to-date examples of ongoing work, often in the context of a specific clinical need. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Features: Covers a number of cutting-edge topics related to regenerative medicine and tissue engineering Includes an introductory chapter on materials science Features a number of the contributors who are world-class researchers, one of whom is Dr. Anthony Atala, whose work dealing with organ regenerative engineering was featured on Sixty Minutes Incorporates problem-based learning throughout the text, which is not hypothetical but based on actual biological, engineering, or clinical scenarios Combining science, engineering and medicine, Regenerative Engineering incorporates all of the essential elements needed for further advancement in this field. The book explores the development and examination of vital organs and tissue types and addresses concerns as it relates to the regenerative engineering of various organ tissues, vascular tissues, bone, ligament, neural tissue, and the interfaces between tissues.

Dose, Benefit, and Risk in Medical Imaging (Hardcover): Lawrence T. Dauer, Bae P. Chu, Pat B. Zanzonico Dose, Benefit, and Risk in Medical Imaging (Hardcover)
Lawrence T. Dauer, Bae P. Chu, Pat B. Zanzonico
R4,515 Discovery Miles 45 150 Ships in 12 - 17 working days

This timely overview of dose, benefit, and risk in medical imaging explains to readers how to apply this information for informed decision-making that improves patient outcomes. The chapters cover patient and physician perspectives, referral guidelines, appropriateness criteria, and quantifying medical imaging benefits. The authors have included essential discussion about radiologic physics in medical imaging, fundamentals of dose and image quality, risk assessment, and techniques for optimization and dose reduction. The book highlights practical implementation aspects with useful case studies and checklists for treatment planning. Clinicians, students, residents, and professionals in medical physics, biomedical engineering, radiology, oncology, and allied disciplines will find this book an essential resource with the following key features: Discusses risk, benefit, dose optimization, safety, regulation, radiological protection, and shared & informed decision-making. Covers regulatory oversight by government agencies, manufacturers, and societies. Highlights best practices for improving patient safety and outcomes. Gives guidelines on doses associated with specific procedures.

Cardiovascular Imaging and Image Analysis (Hardcover): Ayman El-Baz, Jasjit S. Suri Cardiovascular Imaging and Image Analysis (Hardcover)
Ayman El-Baz, Jasjit S. Suri
R6,151 Discovery Miles 61 510 Ships in 12 - 17 working days

This book covers the state-of-the-art approaches for automated non-invasive systems for early cardiovascular disease diagnosis. It includes several prominent imaging modalities such as MRI, CT, and PET technologies. There is a special emphasis placed on automated imaging analysis techniques, which are important to biomedical imaging analysis of the cardiovascular system. Novel 4D based approach is a unique characteristic of this product. This is a comprehensive multi-contributed reference work that will detail the latest developments in spatial, temporal, and functional cardiac imaging. The main aim of this book is to help advance scientific research within the broad field of early detection of cardiovascular disease. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in biomedical image analysis. Key Features: Includes state-of-the art 4D cardiac image analysis Explores the aspect of automated segmentation of cardiac CT and MR images utilizing both 3D and 4D techniques Provides a novel procedure for improving full-cardiac strain estimation in 3D image appearance characteristics Includes extensive references at the end of each chapter to enhance further study

Diagnostic Ultrasound - Physics and Equipment (Hardcover, 3rd edition): Kevin Martin, Abigail Thrush, Peter Hoskins Diagnostic Ultrasound - Physics and Equipment (Hardcover, 3rd edition)
Kevin Martin, Abigail Thrush, Peter Hoskins
R5,408 Discovery Miles 54 080 Ships in 12 - 17 working days

This popular text provides a comprehensive, yet accessible, introduction to the physics and technology of medical ultrasound, with high quality ultrasound images and diagrams throughout. Covering all aspects of the field at a level that meetings the requirements of accredited sonography courses, it is ideal for both trainee and qualified healthcare professionals practising ultrasound in a clinical setting. Building on the content of previous editions, this third edition provides the latest guidance relating to ultrasound technology, quality assurance and safety and discusses the latest techniques.

Biomechanics of the Upper Limbs - Mechanics, Modeling and Musculoskeletal Injuries, Second Edition (Paperback, 2nd edition):... Biomechanics of the Upper Limbs - Mechanics, Modeling and Musculoskeletal Injuries, Second Edition (Paperback, 2nd edition)
Andris Freivalds
R1,696 Discovery Miles 16 960 Ships in 12 - 17 working days

There is already a wealth of literature covering cumulative trauma disorders and medical management, as well as the biomechanics of manual material handling and lower back problems. However, despite a spike in the number of work-related musculoskeletal disorders (WRMSDs) in the upper limbs-due to a sharp increase in the amount of computer-related jobs-few if any books have focused exclusively on WRMSDs, until now. Biomechanics of the Upper Limbs: Mechanics, Modeling and Musculoskeletal Injuries, Second Edition offers vital information and tools to improve analysis of external forces and their effects on the human body. This can help ergonomists better understand job stressors and the role they play in the development of disorders, enabling them to modify the work environment and educate practitioners to better control harmful situations. Using the author's medical and engineering expertise to distill essential subject matter and useful technical data, this comprehensive text explores: Biomechanics of the upper limbs and the motor control system The structure and physiology of the human musculoskeletal and neuromuscular systems Recent research findings and solutions to various ergonomic problems Models of various components of the neuromuscular systems, as well as larger systems in the upper limbs Risk factors for disorders and tools used to identify their causes Designed as a textbook for a typical semester-long graduate-level engineering or kinesiology course, this book includes a link to an ancillary website that offers materials such as PowerPoint (R) slides, sample exams, and an instructor's manual with complete solutions. It also serves as a practical, up-to-date, engineering-oriented resource for researchers, industrial ergonomists, industrial hygienists, and medical professionals who require supplementary material.

Advanced Radiation Protection Dosimetry (Hardcover): Shaheen Dewji, Nolan E. Hertel Advanced Radiation Protection Dosimetry (Hardcover)
Shaheen Dewji, Nolan E. Hertel
R5,976 Discovery Miles 59 760 Ships in 12 - 17 working days

Although many radiation protection scientists and engineers use dose coefficients, few know the origin of those dose coefficients. This is the first book in over 40 years to address the topic of radiation protection dosimetry in intimate detail. Advanced Radiation Protection Dosimetry covers all methods used in radiation protection dosimetry, including advanced external and internal radiation dosimetry concepts and regulatory applications. This book is an ideal reference for both scientists and practitioners in radiation protection and students in graduate health physics and medical physics courses. Features: A much-needed book filling a gap in the market in a rapidly expanding area Contains the history, evolution, and the most up-to-date computational dosimetry models Authored and edited by internationally recognized authorities and subject area specialists Interrogates both the origins and methodologies of dose coefficient calculation Incorporates the latest international guidance for radiation dosimetry and protection

Microarray Image and Data Analysis - Theory and Practice (Paperback): Luis Rueda Microarray Image and Data Analysis - Theory and Practice (Paperback)
Luis Rueda
R1,806 Discovery Miles 18 060 Ships in 12 - 17 working days

Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book: Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalization Features cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networks Covers different types of microarrays such as DNA, protein, tissue, and low- and high-density oligonucleotide arrays Examines the current state of various microarray technologies, including their availability and affordability Explains how data generated by microarray experiments are analyzed to obtain meaningful biological conclusions An essential reference for academia and industry, Microarray Image and Data Analysis: Theory and Practice provides readers with valuable tools and techniques that extend to a wide range of biological studies and microarray platforms.

Engineering Genetic Circuits (Paperback): Chris J Myers Engineering Genetic Circuits (Paperback)
Chris J Myers
R1,855 Discovery Miles 18 550 Ships in 12 - 17 working days

An Introduction to Systems Bioengineering Takes a Clear and Systematic Engineering Approach to Systems Biology Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits. After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits. This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.

Support Vector Machines and Their Application in Chemistry and Biotechnology (Paperback): Yi-Zeng Liang, Qing-Song Xu,... Support Vector Machines and Their Application in Chemistry and Biotechnology (Paperback)
Yi-Zeng Liang, Qing-Song Xu, Hong-Dong Li, Dong-Sheng Cao
R1,767 Discovery Miles 17 670 Ships in 12 - 17 working days

Support vector machines (SVMs) are used in a range of applications, including drug design, food quality control, metabolic fingerprint analysis, and microarray data-based cancer classification. While most mathematicians are well-versed in the distinctive features and empirical performance of SVMs, many chemists and biologists are not as familiar with what they are and how they work. Presenting a clear bridge between theory and application, Support Vector Machines and Their Application in Chemistry and Biotechnology provides a thorough description of the mechanism of SVMs from the point of view of chemists and biologists, enabling them to solve difficult problems with the help of these powerful tools. Topics discussed include: Background and key elements of support vector machines and applications in chemistry and biotechnology Elements and algorithms of support vector classification (SVC) and support vector regression (SVR) machines, along with discussion of simulated datasets The kernel function for solving nonlinear problems by using a simple linear transformation method Ensemble learning of support vector machines Applications of support vector machines to near-infrared data Support vector machines and quantitative structure-activity/property relationship (QSAR/QSPR) Quality control of traditional Chinese medicine by means of the chromatography fingerprint technique The use of support vector machines in exploring the biological data produced in OMICS study Beneficial for chemical data analysis and the modeling of complex physic-chemical and biological systems, support vector machines show promise in a myriad of areas. This book enables non-mathematicians to understand the potential of SVMs and utilize them in a host of applications.

Computational Vision and Medical Image Processing: VipIMAGE 2011 (Paperback): Joao Manuel R.S. Tavares, R.M. Natal Jorge Computational Vision and Medical Image Processing: VipIMAGE 2011 (Paperback)
Joao Manuel R.S. Tavares, R.M. Natal Jorge
R2,161 Discovery Miles 21 610 Ships in 12 - 17 working days

This book contains invited lecturers and full papers presented at VIPIMAGE 2011 - III ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing (Olhao, Algarve, Portugal, 12-14 October 2011). International contributions from 16 countries provide a comprehensive coverage of the current state-of-the-art in: Image Processing and Analysis; Tracking and Analyze Objects in Images; Segmentation of Objects in Images; 3D Vision; Signal Processing; Data Interpolation, Registration, Acquisition and Compression; Objects Simulation; Medical Imaging; Virtual Reality; Software Development for Image Processing and Analysis; Computer Aided Diagnosis, Surgery, Therapy and Treatment; Computational Bioimaging and Visualization; Telemedicine Systems and their Applications. Related techniques also covered in this book include the level set method, finite element method, modal analyses, stochastic methods, principal and independent components analyses and distribution models. Computational Vision and Medical Image Processing - VIPIMAGE 2011 will be useful to academics, researchers and professionals in Computational Vision (Image Processing and Analysis), Computer Sciences, Computational Mechanics and Medicine.

Flexible Batteries (Hardcover): Ye Zhang, Lie Wang, Yang Zhao, Huisheng Peng Flexible Batteries (Hardcover)
Ye Zhang, Lie Wang, Yang Zhao, Huisheng Peng
R2,304 Discovery Miles 23 040 Ships in 12 - 17 working days

Flexible Batteries highlights the key advances in flexible batteries, a booming new direction in the energy storage field. The authors first introduce lithium-ion batteries, which are currently the most widely used batteries. Flexible aqueous batteries such as aqueous lithium-ion, sodium-ion, and zinc-ion batteries are discussed subsequently due to the safety concerns in organic electrolytes. Since flexible metal-air batteries are recognized as primary choices for the next generation, the authors take lithium-air and aluminum-air batteries as examples to explore their applications in flexible battery construction. They further summarize flexible batteries under the most challenging working conditions such as stretching and integrating flexible batteries with flexible energy harvesting devices, sensors, and supercapacitors. Covering both fundamental and application development, this book may effectively bridge academics and industry. It will be helpful not only to scholars and students studying materials science and engineering, chemical engineering, physics, energy science, and biomedical science but also to scientists and engineers in the industry.

Auditory Effects of Microwave Radiation (Paperback, 1st ed. 2021): James C. Lin Auditory Effects of Microwave Radiation (Paperback, 1st ed. 2021)
James C. Lin
R1,914 Discovery Miles 19 140 Ships in 10 - 15 working days

This book examines the human auditory effects of exposure to directed beams of high-power microwave pulses, which research results have shown can cause a cascade of health events when aimed at a human subject or the subject's head. The book details multidisciplinary investigations using physical theories and models, physiological events and phenomena, and computer analysis and simulation. Coverage includes brain anatomy and physiology, dosimetry of microwave power deposition, microwave auditory effect, interaction mechanisms, shock/pressure wave induction, Havana syndrome, and application in microwave thermoacoustic tomography (MTT). The book will be welcomed by scientists, academics, health professionals, government officials, and practicing biomedical engineers as an important contribution to the continuing study of the effects of microwave pulse absorption on humans.

Motor Cortex in Voluntary Movements - A Distributed System for Distributed Functions (Hardcover, New): Alexa Riehle, Eilon... Motor Cortex in Voluntary Movements - A Distributed System for Distributed Functions (Hardcover, New)
Alexa Riehle, Eilon Vaadia
R5,124 Discovery Miles 51 240 Ships in 12 - 17 working days

As one of the first cortical areas to be explored experimentally, the motor cortex continues to be the focus of intense research. Motor Cortex in Voluntary Movements: A Distributed System for Distributed Functions presents developments in motor cortex research, making it possible to understand and interpret neural activity and use it to reconstruct movements. Featuring viewpoints based on monkey and human studies, the book focuses on how neuronal activity changes during learning, discusses what the motor cortex encodes for, and covers the neuronal representations of voluntary movements and the mechanism of their generation during learning. Section 1 uses functional neuroanatomy and imaging studies to describe motor cortical function, and Section 2 provides an overview of studies about neural representations in the motor cortex. The third section concentrates on motor learning, and the final section highlights the reconstruction of movements using brain activity. Revealing many exciting applications of this rapidly expanding science, this book enhances our understanding of the generation of motor commands. It is an essential resource for neuroscientists interested in motor function, rehabilitation medicine practitioners, and biomedical engineers.

Bio-Imaging - Principles, Techniques, and Applications (Paperback): Rajagopal Vadivambal, Digvir S. Jayas Bio-Imaging - Principles, Techniques, and Applications (Paperback)
Rajagopal Vadivambal, Digvir S. Jayas
R2,534 Discovery Miles 25 340 Ships in 12 - 17 working days

Highlights the Emergence of Image Processing in Food and Agriculture In addition to uses specifically related to health and other industries, biological imaging is now being used for a variety of applications in food and agriculture. Bio-Imaging: Principles, Techniques, and Applications fully details and outlines the processes of bio-imaging applicable to food and agriculture, and connects other bio-industries, as well as relevant topics. Due to the noncontact and nondestructive nature of the technology, biological imaging uses unaltered samples, and allows for internal quality evaluation and the detection of defects. Compared to conventional methods, biological imaging produces results that are more consistent and reliable, and can ensure quality monitoring for a variety of practices used in food and agriculture industries as well as many other biological industries. The book highlights every imaging technique available along with their components, image acquisition procedures, advantages, and comparisons to other approaches. Describes essential components of imaging technique in great detail Incorporates case studies in appropriate chapters Contains a wide range of applications from a number of biological fields Bio-Imaging: Principles, Techniques, and Applications focuses on the imaging techniques for biological materials and the application of biological imaging. This technology, which is quickly becoming a standard practice in agriculture and food-related industries, can aid in enhanced process efficiency, quality assurance, and food safety management overall.

Recognition Receptors in Biosensors (Hardcover, 2010 ed.): Mohammed Zourob Recognition Receptors in Biosensors (Hardcover, 2010 ed.)
Mohammed Zourob
R5,816 Discovery Miles 58 160 Ships in 10 - 15 working days

Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, "attractive" force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.

Bioengineering of the Skin - Water and the Stratum Corneum, 2nd Edition (Hardcover, 2nd edition): Joachim W. Fluhr, Peter... Bioengineering of the Skin - Water and the Stratum Corneum, 2nd Edition (Hardcover, 2nd edition)
Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach
R6,000 Discovery Miles 60 000 Ships in 12 - 17 working days

Bioengineering of the skin, or more precisely the biophysical assessment of skin physiology, is moving rapidly from a descriptive approach to a deeper understanding of biophysical and biochemical processes. This second edition of the popular text Bioengineering of the Skin: Water and Stratum Corneum reflects the progress in the field, focusing on the dramatically improved understanding of skin physiology. Specifically, it reviews the shift in our understanding of the stratum corneum from an inert surrounding sheet to a biologically active compartment. The stratum corneum is the interface between the sometimes harsh environment and the internal turmoil of the human body. Based on a large number of recent publications, this book explains the mechanisms involved in stratum corneum barrier function and hydration. It reflects 10 years of progress not only of the non-invasive biophysical assessment of skin physiology parameter, but also of the perfection of the available devices. It brings all research on epidermal water and transepidermal water loss in health and disease up-to-date with the revision of existing chapters as well as added chapters from new contributors on hydration and itching. This edition also includes new guidelines on the standardization of measurements. Bioengineering of the Skin will enhance communication within the research community and will be useful for scientists in the skin bioengineering field by presenting methods that offer reliable and reproducible approaches for product testing in the pharmaceutical and cosmetic industries, as well as for basic research.

Image Processing - Tensor Transform and Discrete Tomography with MATLAB  (R) (Paperback): Artyom M. Grigoryan, Merughan M.... Image Processing - Tensor Transform and Discrete Tomography with MATLAB (R) (Paperback)
Artyom M. Grigoryan, Merughan M. Grigoryan
R2,181 Discovery Miles 21 810 Ships in 12 - 17 working days

Focusing on mathematical methods in computer tomography, Image Processing: Tensor Transform and Discrete Tomography with MATLAB (R) introduces novel approaches to help in solving the problem of image reconstruction on the Cartesian lattice. Specifically, it discusses methods of image processing along parallel rays to more quickly and accurately reconstruct images from a finite number of projections, thereby avoiding overradiation of the body during a computed tomography (CT) scan. The book presents several new ideas, concepts, and methods, many of which have not been published elsewhere. New concepts include methods of transferring the geometry of rays from the plane to the Cartesian lattice, the point map of projections, the particle and its field function, and the statistical model of averaging. The authors supply numerous examples, MATLAB (R)-based programs, end-of-chapter problems, and experimental results of implementation. The main approach for image reconstruction proposed by the authors differs from existing methods of back-projection, iterative reconstruction, and Fourier and Radon filtering. In this book, the authors explain how to process each projection by a system of linear equations, or linear convolutions, to calculate the corresponding part of the 2-D tensor or paired transform of the discrete image. They then describe how to calculate the inverse transform to obtain the reconstruction. The proposed models for image reconstruction from projections are simple and result in more accurate reconstructions. Introducing a new theory and methods of image reconstruction, this book provides a solid grounding for those interested in further research and in obtaining new results. It encourages readers to develop effective applications of these methods in CT.

Regenerative Engineering - Advanced Materials Science Principles (Hardcover): Yusuf Khan, Cato T. Laurencin Regenerative Engineering - Advanced Materials Science Principles (Hardcover)
Yusuf Khan, Cato T. Laurencin
R6,260 Discovery Miles 62 600 Ships in 12 - 17 working days

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

Quality Control Training Manual - Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies... Quality Control Training Manual - Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies Laboratories (Paperback)
Syed Imtiaz Haider, Syed Erfan Asif
R1,684 Discovery Miles 16 840 Ships in 12 - 17 working days

Written to help companies comply with GMP, GLP, and validation requirements imposed by the FDA and regulatory bodies worldwide, Quality Control Training Manual: Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies Laboratories presents cost-effective training courses that cover how to apply advances in the life sciences to produce commercially viable biotech products and services in terms of quality, safety, and efficacy. This book and its accompanying downloadable resources comprise detailed text, summaries, test papers, and answers to test papers, providing an administrative solution for management. Provides the FDA, Health Canada, WHO, and EMEA guidelines directly applicable to pharmaceutical laboratory-related issues Offers generic formats and styles that can be customized to any organization and help management build quality into routine operations to comply with regulatory requirements Contains ready-to-use training courses that supply a good source of training material for experienced and inexperienced practitioners in the biotechnology/biopharmaceutical industries Includes downloadable resources with downloadable training courses that can be adopted and directly customized to a particular organization Supplies ready-to-use test papers that allow end users to record all raw data up to the issuance of the attached certificate The biotechnology/bioscience industries are regulated worldwide to be in compliance with cGMP and GLP principles, with particular focus on safety issues. Each company must create a definite training matrix of its employees. The training procedures in this book enable end users to understand the principles and elements of manufacturing techniques and provide documentation language ranging from the generic to the specific. The training courses on the downloadable resources supply valuable tools for developing training matrices to achieve FDA, Health Canada, EMEA, MHRA UK, WHO, and GLP compliance.

Natural Biomarkers for Cellular Metabolism - Biology, Techniques, and Applications (Paperback): Vladimir V. Ghukasyan, Ahmed A.... Natural Biomarkers for Cellular Metabolism - Biology, Techniques, and Applications (Paperback)
Vladimir V. Ghukasyan, Ahmed A. Heikal
R1,790 Discovery Miles 17 900 Ships in 12 - 17 working days

From the Lab to Clinical Settings-Advances in Quantitative, Noninvasive Optical Diagnostics Noninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of new therapeutic targets for drug discoveries. Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications delves into the current state of knowledge on intrinsic fluorescent biomarkers and highlights recent developments in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. Autofluorescent Biomarkers for Biomedical Diagnostics The book's first section introduces the fundamentals of cellular energy metabolism as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods, including experimental design, calibration, pitfalls, and remedies of data acquisition and analysis. The last two sections highlight advances in biomedical and biochemical applications, such as monitoring stem cell differentiation in engineered tissues and diagnosing cancer and ophthalmic diseases quantitatively and noninvasively. Tailored to Interdisciplinary Researchers Covering cell biology, imaging techniques, and clinical diagnostics, this book provides readers with a complete guide to studying cellular/tissue metabolism under healthy, diseased, and environment-induced stress conditions using natural biomarkers. The book is designed for graduate and advanced undergraduate students, biophysics instructors, medical researchers, and those in pharmaceutical R&D.

Cell and Matrix Mechanics (Paperback): Roland Kaunas, Assaf Zemel Cell and Matrix Mechanics (Paperback)
Roland Kaunas, Assaf Zemel
R2,167 Discovery Miles 21 670 Ships in 12 - 17 working days

Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts Cell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell-matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models. Summarizes the Three Hierarchical Levels of Cell Mechanics The book contains 14 chapters and is organized into three sections. The first section focuses on the molecular level, the second section details mechanics at the cellular level, and the third section explores cellular mechanics at the tissue level. The authors offer a thorough description of the roles of mechanical forces in cell and tissue biology, and include specific examples. They incorporate descriptions of associated theoretical models, and provide the data and modeling framework needed for a multi-scale analysis. In addition, they highlight the pioneering studies in cell-matrix mechanics by Albert K. Harris. The topics covered include: The passive and active mechanical properties of cytoskeletal polymers and associated motor proteins along with the behavior of polymer networks The mechanical properties of the cell membrane, with an emphasis on membrane protein activation caused by membrane forces The hierarchical organization of collagen fibrils, revealing that a delicate balance exists between specific and nonspecific interactions to result in a structure with semicrystalline order as well as loose associations The roles of matrix mechanical properties on cell adhesion and function along with different mechanical mechanisms of cell-cell interactions The effects of mechanical loading on cell cytoskeletal remodeling, summarizing various modeling approaches that explain possible mechanisms regulating the alignment of actin stress fibers in response to stretching The mechanical testing of cell-populated collagen matrices, along with theory relating the passive and active mechanical properties of the engineered tissues Cell migration behavior in 3-D matrices and in collective cell motility The role of mechanics in cartilage development The roles of both cellular and external forces on tissue morphogenesis The roles of mechanical forces on tumor growth and cancer metastasis Cell and Matrix Mechanics succinctly and systematically explains the roles of mechanical forces in cell-matrix biology. Practitioners and researchers in engineering and physics, as well as graduate students in biomedical engineering and mechanical engineering related to mechanobiology, can benefit from this work.

Introduction to Megavoltage X-Ray Dose Computation Algorithms (Hardcover): Jerry Battista Introduction to Megavoltage X-Ray Dose Computation Algorithms (Hardcover)
Jerry Battista
R6,314 Discovery Miles 63 140 Ships in 12 - 17 working days

Read an exclusive interview with Dr. Jerry Battista here. A critical element of radiation treatment planning for cancer is the accurate prediction and delivery of a tailored radiation dose distribution inside the patient. Megavoltage x-ray beams are aimed at the tumour, while collateral damage to nearby healthy tissue and organs is minimized. The key to optimal treatment therefore lies in adopting a trustworthy three-dimensional (3D) dose computation algorithm, which simulates the passage of both primary and secondary radiation throughout the exposed tissue. Edited by an award-winning university educator and pioneer in the field of voxel-based radiation dose computation, this book explores the physics and mathematics that underlie algorithms encountered in contemporary radiation oncology. It is an invaluable reference for clinical physicists who commission, develop, or test treatment planning software. This book also covers a core topic in the syllabus for educating graduate students and residents entering the field of clinical physics. This book starts with a historical perspective gradually building up to the three most important algorithms used for today's clinical applications. These algorithms can solve the same general radiation transport problem from three vantages: firstly, applying convolution-superposition principles (i.e. Green's method); secondly, the stochastic simulation of radiation particle interactions with tissue atoms (i.e. the Monte Carlo method); and thirdly, the deterministic solution of the fundamental equations for radiation fields of x-rays and their secondary particles (i.e. the Boltzmann method). It contains clear, original illustrations of key concepts and quantities thoughout, supplemented by metaphors and analogies to facilitate comprehension and retention of knowledge. Features: Edited by an authority in the field, enhanced with chapter contributions from physicists with clinical experience in the fields of computational dosimetry and dose optimization Contains examples of test phantom results and clinical cases, illustrating pitfalls to avoid in clinical applications to radiation oncology Introduces four-dimensional (4D) dose computation, on-line dose reconstruction, and dose accumulation that accounts for tissue displacements and motion throughout a course of radiation therapy

Wireless Medical Systems and Algorithms - Design and Applications (Paperback): Pietro Salvo, Miguel Hernandez-Silveira Wireless Medical Systems and Algorithms - Design and Applications (Paperback)
Pietro Salvo, Miguel Hernandez-Silveira
R2,300 Discovery Miles 23 000 Ships in 12 - 17 working days

Wireless Medical Systems and Algorithms: Design and Applications provides a state-of-the-art overview of the key steps in the development of wireless medical systems, from biochips to brain-computer interfaces and beyond. The book also examines some of the most advanced algorithms and data processing in the field. Addressing the latest challenges and solutions related to the medical needs, electronic design, advanced materials chemistry, wireless body sensor networks, and technologies suitable for wireless medical devices, the text: Investigates the technological and manufacturing issues associated with the development of wireless medical devices Introduces the techniques and strategies that can optimize the performances of algorithms for medical applications and provide robust results in terms of data reliability Includes a variety of practical examples and case studies relevant to engineers, medical doctors, chemists, and biologists Wireless Medical Systems and Algorithms: Design and Applications not only highlights new technologies for the continuous surveillance of patient health conditions, but also shows how disciplines such as chemistry, biology, engineering, and medicine are merging to produce a new class of smart devices capable of managing and monitoring a wide range of cognitive and physical disabilities.

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