Your cart is empty
The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook: Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.
The nanosciences are a rapidly expanding field of research with a wide applicability to all areas of health and disease prevention. This book, covers the regulation of nanomedicine, nanotubes, topical applications of nanoparticles, nanocrystals, antioxidant nanoparticles, lipid nanocapsules, nanotheragnostic colloids, nanotechnology in the control of infectious disease, virus-based nanoparticles and the safety of nanoparticles. It also covers nanomedicine in relation to pulmonary drug delivery, the control of infectious disease, radiation protection, arthritis, cancer nanomedicine, blood diseases, neurodegenerative disorders, and tissue and implant engineering.
Microbial applications encompass areas including biotechnology, chemical engineering, and alternative fuel development. Research on their technological developments cover many aspects of work using microbes as cell factories. The fields of biotechnology, chemical engineering, pharmaceuticals, diagnostics and medical device development also employ these microbial products. There is an urgent need to integrate all these disciplines that caters to the need of all those who are interested to work in the area of microbial technologies. This book is a step forward to integrate the aforesaid frontline branches into an interdisciplinary research work quenching the academic as well as research thirst of all those concerned about microbes in the respective area of biotechnology, chemical engineering, and pharmaceuticals. All the chapters in this book are related to important research on microbial applications, written by international specialists for researchers and academics in the concerned disciplines. This publication aims to provide a detailed compendium of experimental work and information used to investigate different aspects of microbial technologies, their products as well as interdisciplinary interactions including biochemistry of metabolites, in a manner that reflects the recent developments of relevance to researchers/scientists investigating microbes.
This well-established book on injury biomechanics has been extensively revised and expanded for this new edition. It now includes a fundamental treatment of the mechanics at a cellular level, written by the new coauthor Prof. Barclay Morrison III from Columbia University. Furthermore, considerably more attention is paid to computer modeling, and in particular modeling the human body. The book addresses a wide range of topics in injury biomechanics, including anatomy, injury classification, injury mechanisms, and injury criteria. Further, it provides essential information on regional injury reference values, or injury criteria, that are either currently in use or proposed by both US and European communities. Although the book is intended as an introduction for doctors and engineers who are newcomers to the field of injury biomechanics, sufficient references are provided for those who wish to conduct further research, and even established researchers will find it useful as a reference guide to the biomechanical background of each proposed injury mechanism and injury criterion.
This second edition of the "Encyclopedia of Molecular Cell Biology and Molecular Medicine" covers the molecular and cellular basis of life, disease, and therapy at university and professional researcher level. With its 16 volumes, this is the most comprehensive and detailed treatment of molecular cell biology and molecular medicine available today. It represents a single source library for Molecular Biologists Cell Biologist Biochemists Structural Biologists Gene Technologists Developmental Biologists Medicinal Chemists Physicians Biotechnologists Pharmacologists
An Editorial Board composed of renowned experts from all over the world - Nobel laureates, including the 2007 Nobel Prize winner in medicine, Sir Martin Evans, Lasker Award winners and directors of prestigious institutes and university departments - guarantees the high quality and comprehensive scope of this work. All major disciplines comprising and supporting molecular cell biology and molecular medicine are covered in true Encyclopedic detail.
Each of the over 400 articles is conceived as a self-contained treatment and begins with an outline and a keyword section, including definitions. Descriptive illustrations - many in colour -, informative tables and a glossary of basic terms in each volume enable readers to understand articles without the need to consult a dictionary, textbook or other work. Numerous cross-references and a comprehensive bibliography round off every article.
Praise from the reviews:
,,"." It goes without saying that no library can afford to be without this new edition. Everyone working in the areas of molecular biology, genome research, medical science, or clinical research needs to haveaccess to these volumes... "" Angewandte Chemie
,,"." an authoritative reference source of the highest quality... It is extremely well written and well illustrated...""American Reference Books Annual (Library & Information Science Annual - on the first edition)
For further details please visit our homepage at www.meyers-emcbmm.de
This book focuses on a topical and timely aspect of prokaryotic biology - the biology of prokaryotic multiple chaperonins. Chaperonins are a class of molecular chaperones, the proteins that assist folding of other proteins in the cell. The book begins with an introductory chapter on the structural and functional aspects of chaperonins, followed by an outline on different mechanisms of their regulation. Subsequently, the book provides a comprehensive overview on how the multiple-chaperonins have embraced biological requirements in different classes of microbes, discussing their functional diversity, evolutionary paths and the latest advances in the field. It brings together leading experts from across the globe in offering a detailed account of the structural, biochemical, functional and phylogenetic characteristics of microbial chaperonins for students, researchers and teachers working in the area of microbiology/ biophysics/ parasitology - more specifically, in protein folding pathways.
Assistive technologies for the old and people with disabilities is now a very active field of research. It also constitutes a very profitable market (expected to reach US $60 billion p.a. by 2018). The book covers key aspects of this important field and provides guidelines for developing assistive technologies in smart environments. The book also presents the new paradigm of open innovation used by the most prolific research teams around the world. The latest developments in the field are given. Overall this book will be a reference for researchers, practitioners and engineers.
The increasing interest in the bio-impedance analysis in various fields has increased the demand for portable and low-cost impedance analyzers that can be used in the field. Simplifying the hardware is crucial to maintaining low-cost and portability, but this is not an easy task due to the need for accurate phase and magnitude measurements. This book discusses different portable impedance analyzers design techniques. Additionally, complete designs using two different approaches are reported. The first approach utilizes a commercially available single chip solution while the second one is based on a new measurement technique that eliminates the need to measure the phase by using a software algorithm to extract it from the magnitude information. Applications to the measurement of fruit bio-impedance are emphasized and compared with measurements from professional stand-alone impedance analyzers.
This book introduces advanced and hybrid compression techniques specifically used for medical images. The book discusses conventional compression and compressive sensing (CS) theory based approaches that are designed and implemented using various image transforms, such as: Discrete Fourier Transform (DFT), Discrete Cosine Transform (DCT), Discrete Wavelet Transform (DWT), and Singular Value Decomposition (SVD) and greedy based recovery algorithm. The authors show how these techniques provide simulation results of various compression techniques for different types of medical images, such as MRI, CT, US, and x-ray images. Future research directions are provided for medical imaging science. The book will be a welcomed reference for engineers, clinicians, and research students working with medical image compression in the biomedical imaging field. Covers various algorithms for data compression and medical image compression; Provides simulation results of compression algorithms for different types of medical images; Provides study of compressive sensing theory for compression of medical images.
This book focuses on applications of micro CT, CBCT and CT in medicine and engineering, comprehensively explaining the basic principles of these techniques in detail, and describing their increasing use in the imaging field. It particularly highlights the scanning procedure, which represents the most crucial step in micro CT, and discusses in detail the reconstruction process and the artifacts related to the scanning processes, as well as the imaging software used in analysis. Written by international experts, the book illustrates the application of micro CT in different areas, such as dentistry, medicine, tissue engineering, aerospace engineering, geology, material engineering, civil engineering and additive manufacturing. Covering different areas of application, the book is of interest not only to specialists in the respective fields, but also to broader audience of professionals working in the fields of imaging and analysis, as well as to students of the different disciplines.
This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.
Fall-induced hip fracture is an epidemic health risk among elderly people. This book presents an image-based multilevel modeling approach to understanding the biomechanics involved in fall-induced hip fracture. By hierarchically integrating a body-level dynamics model, a femur-level finite element model, and a local bone failure model, the biomechanics approach is able to simulate all stages in sideways falls and to incorporate all biomechanical variables affecting hip fracture. This book is useful for clinicians to accurately evaluate fracture risk, for biomechanical engineers to virtually test hip protective devices, and for biomedical students to learn image-based biomechanical modeling techniques. This book also covers: Biomechanical viewing on bone composition, bone remodeling, and bone strength Bone imaging and information captured for constructing biomechanical models Bone mechanical testing and mechanical properties required for biomechanical modeling
The volume includes presentations of technological and research accomplishments along with novel approaches in nanomedicine and nanotechnology. It explores the different types of nanomedicinal drugs with their production and commercial significance. Other topics discussed are the use of natural and synthetic nanoparticles for the production of drugs, different types of nanoparticles systems, drug carriers, wound-healing antimicrobial activity, effects of natural materials in nanomedicine, and toxicity of nanoparticles. The valuable information presented in this volume will help to keep those in this field up to date on the key findings, observations, and fabrication of drugs related to nanomedicine and nanotechnology. With chapters written by prominent researchers from academia, industry, and government and private research laboratories across the world, the book will prove to be a rich resource.
An Introduction to Systems Bioengineering
Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits.
After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits.
This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.
This unique introductory text explains cell functions using the engineering principles of robust devices. Adopting a process-based approach to understanding cell and tissue biology, it describes the molecular and mechanical features that enable the cell to be robust in operating its various components, and explores the ways in which molecular modules respond to environmental signals to execute complex functions. The design and operation of a variety of complex functions are covered, including engineering lipid bilayers to provide fluid boundaries and mechanical controls, adjusting cell shape and forces with dynamic filament networks, and DNA packaging for information retrieval and propagation. Numerous problems, case studies and application examples help readers connect theory with practice, and solutions for instructors and videos of lectures accompany the book online. Assuming only basic mathematical knowledge, this is an invaluable resource for graduate and senior undergraduate students taking single-semester courses in cell mechanics, biophysics and cell biology.
This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, inflammation, polymeric biomaterials, neural injury, cartilage regeneration, regeneration in ambystoma, models for regeneration using salamander and zebrafish, and more. The volume also discusses recent advances and their potential in developing future therapies. Innovations in Molecular Mechanisms and Tissue Engineering combines perspectives from the biomedical, bioengineering, and medical fields to present a cutting-edge, multifaceted picture of the tissue engineering and regenerative medicine fields. This installment of Springer's Stem Cell Biology and Regenerative Medicine series is ideal for scientists, clinicians, and researchers in the fields of stem cell biology, regenerative medicine, biomedical engineering, and tissue engineering.
This brief summarizes different types of organic and inorganic nanomaterials for drug delivery in cancer therapy. It highlights that precisely designed nanomaterials will be the next-generation therapeutic agents for cancer treatment.
The field of biomedical engineering has vastly expanded in the past two decades, as reflected in the increased number of bioengineering and biomaterials programs at universities. The growth of this area has outpaced the development of laboratory courses that allow students hands-on experience, since the barriers involved in creating multidisciplinary biomaterials laboratory courses are high. A Laboratory Course in Biomaterials provides a teaching tool comprehensive in scope perspective. Multidisciplinary approach Suitable for junior or senior level laboratory courses in biomaterials and bioengineering, this volume trains students in laboratory skills, data analysis, problem solving, and scientific writing. The text takes a multidisciplinary approach, integrating a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Step-by-step instructions The author presents flexible modules that allow the coursework to be adapted to the needs of different departments. Each module is organized around a central theme, such as drug delivery and natural biomaterials, to enhance student comprehension. This book provides step-by-step descriptions of lab procedures, reagents, equipment, and data processing guidelines. It also includes a series of thought-provoking questions and answers following each experiment, drawn from the author's own experience in teaching a biomaterials laboratory course at the University of Illinois. Timely in its coverage, many of the experiments presented in the book are adapted from research papers reflecting the progress in various disciplines of bioengineering and biomaterials science.
Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field.
The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.
A review of the literature on the environmental health
implications of the developing nanotechnology industry shows that
the potential problem of exposure to airborne nanoparticles has not
been adequately assessed. The health and safety of nanotechnology
workers is of concern because these groups are likely to be exposed
to elevated concentrations of nanomaterials. A gap exists between
currently available particle measurement methods and those
appropriate for nanoaerosol exposure assessment.
"Highly Commended at the BMA Book Awards 2013"
"Extreme Tissue Engineering" is an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field.
Organised into three main sections: chapters 1 to 3 introduce and explain the general problems; chapters 4 to 6 identify and refine how the main factors interact to create the problems and opportunities we know all too well; chapters 7 to 9 argue us through the ways we can use leading-edge (extreme) concepts to build our advanced solutions.
Students and researchers in areas such as stem cell and developmental biology, tissue repair, implantology and surgical sciences, biomaterials sciences and nanobiomedicine, bioengineering, bio-processing and monitoring technologies - from undergraduate and masters to doctoral and post-doctoral research levels - will find "Extreme Tissue Engineering" a stimulating and inspiring text.
Written in a fluid, entertaining style, "Extreme Tissue Engineering" is introductory yet challenging, richly illustrated and truly interdisciplinary.
Plant endophytes are a potential source for the production of bioactive compounds that can fight against devastating diseases in both plants and humans. Among these endophytic microorganisms, endophytic fungi are one of the dominant group of microorganisms with a potential role in plant growth promotion and the discovery of noble bioactive natural products. Endophytic fungi possess several bioactivities like anticancer, antimicrobial, insecticidal, plant growth stimulants, crop protection, phytoremediation, etc. Presence of modular biosynthetic genes clusters like PKS and NRPS in several endophytic fungi underscores the need to understand and explore such organisms. This volume presents and demonstrates the applied aspects of endophytic fungi. Practical applications of such endophytes are discussed in detail, including studies in pharmaceutical development and agricultural management of important microbial diseases. The beneficial effects that endophytic fungi provide to host plants-enhancing growth, increasing fitness, strengthening tolerance to abiotic and biotic stresses through secondary metabolites-are also discussed. The reader is provided with a comprehensive and detailed understanding of such relationships between endophytic fungi and their host.
The book discusses ways to overcome the side effects of using hydrocarbon-based products as energy sources. Hydrocarbons produce raw crude oil waste of around 600,000 metric tons per annum, with a range of uncertainty of 200,000 metric tons per year. The various chapters in this book focus on approaches to reduce these wastes through the application of potential microbes, in a process called bioremediation. The book is a one-stop reference resource on the methods, mechanisms and application of the bio-composites, in the laboratory and field. Focusing on resolving a very pressing environmental issue, it not only provides details of existing challenges, but also offers deeper insights into the possibility of solving problems using hydrocarbon bioremediation.
This book discusses, explains and provides detailed, up-to-date information on physics applied to clinical practice in anesthesiology, with the aid of simple examples from daily life. Almost everything that happens around us, including in the operating room and intensive care units, can be explained by physical laws. An awareness and understanding of relatively simple laws such as Bernoulli's theorem, Hagen-Poiseuille equation and Pascal's principle, to name just a few, offer anesthesiologists and intensivists fascinating insights into why they do what they do. Each of the 16 chapters starts with an everyday phenomenon, explains it with a physical law, and then shows why that law is important in anesthesia practice. Numerous illustrations are included for extra clarity. It is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees, and medical students.
You may like...
Photonics, Volume 4 - Biomedical…
David L Andrews Hardcover
Mathematical Foundations and…
Roustem N. Miftahof, Hong Gil Nam Hardcover
Building Ontologies with Basic Formal…
Robert Arp, Barry Smith, … Paperback
Modelling Optimization and Control of…
Efstratios N. Pistikopoulos Hardcover
Cambridge Texts in Biomedical…
Irving J. Bigio, Sergio Fantini Hardcover R1,346 Discovery Miles 13 460
Managing Discovery in the Life Sciences…
Philip A. Rea, Mark V. Pauly, … Paperback R682 Discovery Miles 6 820
Modeling of Physiological Flows
Davide Ambrosi, Alfio Quarteroni, … Hardcover
Ocean Innovation - Biomimetics Beneath…
Iain A. Anderson, Julian Vincent, … Hardcover R2,853 Discovery Miles 28 530
Implant Surfaces and their Biological…
Ann Wennerberg, Tomas Albrektsson, … Hardcover
Bhupinder Singh Hardcover R3,058 Discovery Miles 30 580