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This book covers the latest research and advancements related to articular cartilage in biology, development, pathology, clinical applications and tissue engineering. The authors take an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science and detailed methological approaches. It is designed to be an all encompassing encyclopedia of articular cartilage. Written at a level that allows wide accessibility, the book's comprehensive focus on multiple aspects of articular cartilage sets it apart from other books.
In this book, leading authors in the field discuss development of Ambient Assisted Living. The contributions have been chosen and invited at the 6th AAL congress, Berlin. It presents new technological developments which support the autonomy and independence of individuals with special needs. As the technological innovation raises also social issues, the book addresses micro and macro economical aspects of assistive systems and puts an additional emphasis on the ethical and legal discussion. The presentation is supported by real world examples and applications.
5thInternational Symposium on the Mechanics of Biological Systems and Materials, Volume 6 of the Proceedings of the 2015SEM Annual Conference& Exposition on Experimental and Applied Mechanics, the sixth volume of nine from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wide range of areas, including: Soft Tissues Mechanics Bio-Engineering and Biomechanics Natural Materials & Bio-Inspiration Novel Techniques and Experiments in Biomechanics Tissue Engineering Cells Mechanics
This brief highlights the association of different performance variables that influences archery performance and the employment of different machine learning algorithms in the identification of potential archers. The sport of archery is often associated with a myriad of performance indicators namely bio-physiological, psychological, anthropometric as well as physical fitness. Traditionally, the determination of potential archers is carried out by means of conventional statistical techniques. Nonetheless, such methods often fall short in associating non-linear relationships between the variables. This book explores the notion of machine learning that is capable of mitigating the aforesaid issue. This book is valuable for coaches and managers in identifying potential archers during talent identification programs.
This book introduces readers to the theory and practice of extrusion bio-printing of scaffolds for tissue engineering applications. The author emphasizes the fundamentals and practical applications of extrusion bio-printing to scaffold fabrication, in a manner particularly suitable for those who wish to master the subject matter and apply it to real tissue engineering applications. Readers will learn to design, fabricate, and characterize tissue scaffolds to be created by means of extrusion bio-printing technology.
Ideal for classroom use and self-study, this book explains the implementation of the most effective modern methods in image analysis, covering segmentation, registration and visualisation, and focusing on the key theories, algorithms and applications that have emerged from recent progress in computer vision, imaging and computational biomedical science. Structured around five core building blocks - signals, systems, image formation and modality; stochastic models; computational geometry; level set methods; and tools and CAD models - it provides a solid overview of the field. Mathematical and statistical topics are presented in a straightforward manner, enabling the reader to gain a deep understanding of the subject without becoming entangled in mathematical complexities. Theory is connected to practical examples in x-ray, ultrasound, nuclear medicine, MRI and CT imaging, removing the abstract nature of the models and assisting reader understanding, whilst computer simulations, online course slides and a solution manual provide a complete instructor package.
Spanning both the history and future of knee replacement, this unique book recounts how artificial knees have reached the stage they are today, and whether their performance can be further improved. The author, who has been designing artificial knees for 50 years, starts the story in the late 1960's with the early pioneers; during the 1970's, the principles for successful artificial knees were established. While many different types were designed, a small number have become by far the most widely utilized. Yet other types of designs, so far little used, along with new materials and the application of computer-assisted surgery, could result in significant advancements in the treatment of knee arthritis. Each chapter provides a detailed description of the origins of the ideas and principles and their rationale, followed by the latest information and evidence. The book begins with an overview of the history and background of the artificial knee, in terms of design and implementation and the thought leaders involved. Fixation, biomechanics, and the types of designs are discussed in detail, both what has worked and what has not, and why. Instrumentation, testing and tribology, and functional evaluation methods are also covered. The book concludes with a look toward the future possibilities for the field of artificial knees. An illustrated glossary of terms, is included for quick reference. The Artificial Knee: An Ongoing Evolution will appeal to orthopedic surgeons and researchers, medical academics and orthopedic companies, and to those with a general interest in artificial knees.
Since the major pioneering of joint replacement surgery more than fifty years ago, much research and progress has been made in the field of arthroplasty with new insights into better materials, types of cement and bone-cell compatible coatings, and a better understanding of the causes of implant failure. With an increasingly ageing population the requirement for arthroplastic surgery is manifest; over 800,000 hips worldwide are replaced each year, and replacement surgery is performed for almost every joint of the body.
"The Engineering of Human Joint Replacements" covers the design, engineering, production and manufacture of human joint replacements, as well as associated engineering concerns such as surface coatings, orthopedic bone cement, the causes and effects of wear and tear, and rapid prototyping for clinical evaluation. Materials evaluation and selection is discussed, as well as production processes and insertion methods. The author provides an overview of skeletal anatomy and the effects of pain and deterioration in order to put the engineering principles into a medical context. Examples of joint replacements for the most common regions of the body are included, and aspects of clinical studies of these cases are discussed.
- Provides an overview of the engineering materials and processes involved in the manufacture of human joint replacements- Sets the scene for engineers and clinicians embarking on research into joint replacements- Includes clinical and industrial examples and points the way to future developments- Provides information on medical device companies with an engineering guide to the requirements for joint replacement
"The Engineering of Human Joint Replacements" bridges the divide between engineering and orthopaedic surgery, offering an introductory text to young engineers entering the field, as well as a reference for medical staff who will benefit from an understanding of the materials and methods used in their design, engineering and manufacture.
"Microalgae Biotechnology for Food, Health and High Value Products" presents the latest technological innovations in microalgae production, market status of algal biomass-based products, and future prospects for microalgal applications. It provides stimulating overviews from different perspectives of application that demonstrate how rapidly the commercial production of microalgae-based food, health and high value products is advancing. It also addresses a range of open questions and challenges in this field. The book highlights the latest advances of interest to those already working in the field, while providing a comprehensive overview for those readers just beginning to learn about the promise of microalgae as a sustainable source of both specialty and commercial products. It offers a valuable asset for commercial algae producers, algae product developers, scientific researchers and students who are dedicated to the advancement of microalgae biotechnology for applications in health, diet, nutrition, cosmetics, biomaterials etc.
"Mechanics of Biological Systems and Materials"," Volume 7: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics," the seventh volume of eight from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wide range of areas, including:
Soft Tissues Mechanics
Natural Materials & Bio-Inspiration
Grids are currently used in many sectors of life sciences, including basic sciences such as genomics, proteomics, and bioinformatics. ""The Handbook of Research on Computational Grid Technologies for Life Sciences, Biomedicine, and Healthcare"" brings together state-of-the art methodologies and developments of grid technologies applied in different fields of life sciences. This ""Handbook of Research"" considers the use of grid technologies to support research and application of each information level where life science research takes place - a useful reference source for academicians, medical practitioners, and researchers involved in all areas of healthcare technologies. It includes: over 25 authoritative contributions by the world's leading experts in grid technologies for life sciences, biomedicine, and healthcare; comprehensive coverage of each specific topic, highlighting recent trends and describing the latest advances in the field; and, more than 1,000 references to existing literature and research on grid technologies for life sciences, biomedicine, and healthcare. A compendium of 230 key terms with detailed definitions, this book is organized by topic and indexed, making it a convenient method of reference for all IT/IS scholars and professionals. It features cross-referencing of key terms, figures, and information pertinent to grid technologies for life sciences, biomedicine, and healthcare.
This book discusses vegetable oil based biolubricants and their applications in the power distribution industry. Vegetable oil based lubricants offer significant advantages over petroleum-based lubricants, including biodegradability, cost-effectiveness, renewability, and lower environmental effects. This book provides a detailed literature survey of modified vegetable oils. It discusses the physical and chemical properties of vegetable oil, and their effects on its applications in tribology. The book discusses additives and enhancements to make vegetable oils suitable for use as lubricating oils and transformer oils in power plants and power distribution grids. The contents of the book will be useful to researchers and professionals as well as policy makers and standards agencies.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A State-of-the-Art Guide to Biomedical Engineering and Design Fundamentals and Applications The two-volume Biomedical Engineering and Design Handbook, Second Edition offers unsurpassed coverage of the entire biomedical engineering field, including fundamental concepts, design and development processes, and applications. This landmark work contains contributions on a wide range of topics from nearly 80 leading experts at universities, medical centers, and commercial and law firms. Volume 1 focuses on the basics of biomedical engineering, including biomedical systems analysis, biomechanics of the human body, biomaterials, and bioelectronics. Filled with more than 500 detailed illustrations, this superb volume provides the foundational knowledge required to understand the design and development of innovative devices, techniques, and treatments. Volume 1 covers: Modeling and Simulation of Biomedical Systems Bioheat Transfer Physical and Flow Properties of Blood Respiratory Mechanics and Gas Exchange Biomechanics of the Respiratory Muscles Biomechanics of Human Movement Biomechanics of the Musculoskeletal System Biodynamics Bone Mechanics Finite Element Analysis Vibration, Mechanical Shock, and Impact Electromyography Biopolymers Biomedical Composites Bioceramics Cardiovascular Biomaterials Dental Materials Orthopaedic Biomaterials Biomaterials to Promote Tissue Regeneration Bioelectricity Biomedical Signal Analysis Biomedical Signal Processing Intelligent Systems and Bioengineering BioMEMS
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A State-of-the-Art Guide to Biomedical Engineering and Design Fundamentals and Applications The two-volume Biomedical Engineering and Design Handbook, Second Edition, offers unsurpassed coverage of the entire biomedical engineering field, including fundamental concepts, design and development processes, and applications. This landmark work contains contributions on a wide range of topics from nearly 80 leading experts at universities, medical centers, and commercial and law firms. Volume 2 provides timely information on breakthrough developments in medical device design, diagnostic equipment design, surgery, rehabilitation engineering, prosthetics design, and clinical engineering. Filled with more than 400 detailed illustrations, this definitive volume examines cutting-edge design and development methods for innovative devices, techniques, and treatments. Volume 2 covers: Medical Product Design FDA Medical Device Requirements Cardiovascular Devices Design of Respiratory Devices Design of Artificial Kidneys Design of Controlled-Release Drug Delivery Systems Sterile Medical Device Package Development Design of Magnetic Resonance Systems Instrumentation Design for Ultrasonic Imaging The Principles of X-Ray Computed Tomography Nuclear Medicine Imaging Instrumentation Breast Imaging Systems Surgical Simulation Technologies Computer-Integrated Surgery and Medical Robotics Technology and Disabilities Applied Universal Design Design of Artificial Arms and Hands for Prosthetic Applications Design of Artificial Limbs for Lower Extremity Amputees Wear of Total Knee and Hip Joint Replacements Home Modification Design Intelligent Assistive Technology Rehabilitators Risk Management in Healthcare Technology Planning for Healthcare Institutions Healthcare Facilities Planning Healthcare Systems Engineering Enclosed Habitat Life Support
Praise for the prior edition "The author has done a magnificent job... this book is highly recommended for introducing biophysics to the motivated and curious undergraduate student." Contemporary Physics "a terrific text ... will enable students to understand the significance of biological parameters through quantitative examples a modern way of learning biophysics." American Journal of Physics "A superb pedagogical textbook... Full-color illustrations aid students in their understanding" Midwest Book Review This new edition provides a complete update to the most accessible yet thorough introduction to the physical and quantitative aspects of biological systems and processes involving macromolecules, subcellular structures, and whole cells. It includes two brand new chapters covering experimental techniques, especially atomic force microscopy, complementing the updated coverage of mathematical and computational tools. The authors have also incorporated additions to the multimedia component of video clips and animations, as well as interactive diagrams and graphs. Key Features: Illustrates biological examples with estimates and calculations of biophysical parameters. Features two brand-new chapters on experimental methods, a general overview and focused introduction to atomic force microscopy. Includes new coverage of important topics such as measures of DNA twist, images of nanoparticle assembly, and novel optical and electron nanoscopy. Provides a guide to investigating current expert biophysical research. Enhanced self-study problems and an updated glossary of terms.
Implantable sensing, whether used for transient or long-term monitoring of in vivo physiological, bio-electrical, bio-chemical and metabolic changes, is a rapidly advancing field of research and development. Underpinned by increasingly small, smart and energy efficient designs, they become an integral part of surgical prostheses or implants for both acute and chronic conditions, supporting optimised, context aware sensing, feedback, or stimulation with due consideration of system level impact. From sensor design, fabrication, on-node processing with application specific integrated circuits, to power optimisation, wireless data paths and security, this book provides a detailed explanation of both the theories and practical considerations of developing novel implantable sensors. Other topics covered by the book include sensor embodiment and flexible electronics, implantable optical sensors and power harvesting. Implantable Sensors and Systems - from Theory to Practice is an important reference for those working in the field of medical devices. The structure of the book is carefully prepared so that it can also be used as an introductory reference for those about to enter into this exciting research and developing field.
This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.
This book offers a complete overview of photonic-enhanced materials from material development to a final photonic biomedical application. It includes fundamental, applied, and industrial photonics. The authors cover synthesis, the modification and the processing of a variety of (bio)polymers including thermoplasts (e.g. polyesters) and hydrogels (e.g. proteins and polysaccharides) for a plethora of applications in the field of optics and regenerative medicine.
Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.
This textbook discusses the basics and clinical aspects of bone research in an accessible way. It aims at enhancing students' understanding of the structure, pathophysiology and regeneration of bone and associated connective tissues. The book covers a diverse aspects of this interdisciplinary field, including immunology, molecular biology and regenerative medicine, as well as tissue engineering and strategies that combine biomaterials, cells and growth-stimulating factors to trigger tissue development and regeneration. As such, the book offers an essential guide for advanced master's students and PhD students in biomedicine, orthopedics and rheumatology.
This timely book presents innovative technologies for use in the diagnosis, monitoring, and treatment of brain disease. These technologies offer exciting possibilities in the medical field owing to their low-cost, portability and safety. The authors address cerebrovascular diseases such as stroke, ischemia, haemorrhage, and vasospasm, these diseases having an ever-increasing societal relevance due to the global ageing population. The authors describe the potential of novel techniques such as microwave imaging and present innovative modalities for treatment of brain tumours using electromagnetic fields and nano-composites, as well as for monitoring brain temperature during surgery. Finally, Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy addresses the perspectives which arise from multi-modal multi-spectral EM modalities, which make a synergic use of the different portions of the electromagnetic spectrum. This text will be of interest to readers from various different areas, given the fundamental interdisciplinarity of the subject matter. This includes researchers or practitioners in the field of electrical engineering, applied physicists, and applied mathematicians working on imaging applications for biomedical and electromagnetic technologies. Neurologists and radiologists may also find this book of interest, as may graduate students in these areas.
This book offers present-day retrospectives and future perspectives on 'phytobiont' studies in the context of phyto-micro restitution, filling some of the information gaps in this promising research field. It discusses several ecosystem restitution strategies using dissimilar groups of microbes alone or in association with plants, as well as advances in metagenomics technology for studying in situ micro and macro communities in contaminated soil. It addresses topics such as the status quo, and the perspectives of microbial researchers and scientists, foresters, students, environmentalists, agriculturists and professional engineers. The rising pollution levels caused by xenobiotics is one of the biggest problems of our times, and as such the book comprehensively elaborates the latest research in this field and describes how the issue can be tackled using micro-organisms. With detailed diagrams and illustrations, the book is a valuable resource for experts and novices in the field of microbial bioremediation, phyto-bioremediation and environmental microbiology
Rapid prototyping is used to design and develop medical devices and instrumentation. This book details research in rapid prototyping of bio-materials for medical applications. It provides a wide variety of examples of medical applications using rapid prototyping, including tissue engineering, dental applications, and bone replacement. Coverage also discusses the emergence of computer aided design in the development of prosthetic devices.
This fully updated second edition provides readers with all they need to understand the use of medical technology in patient care. Incorporating the most recent changes in healthcare, regulations, Standards, and technology, coverage is expanded to include new chapters on device testing, with a particular emphasis on safety inspections, and the interface of medical technology with the electronic medical record. A wide variety of medical instrumentation is discussed, focusing on device types and classifications, and including individual manufacturers as examples. It is designed for readers with a fundamental understanding of anatomy, physiology and medical terminology, as well as electronic concepts such as voltage, current, resistance, impedance, analog and digital signals, and sensors. Additional documents and solutions to end-of-chapter questions accompany the book online, providing biomedical engineering technicians with the resources and tools they need to become knowledgeable and effective members of the patient care team.
These are the proceedings of the International Conference on ISMAC-CVB, held in Palladam, India, in May 2018. The book focuses on research to design new analysis paradigms and computational solutions for quantification of information provided by object recognition, scene understanding of computer vision and different algorithms like convolutional neural networks to allow computers to recognize and detect objects in images with unprecedented accuracy and to even understand the relationships between them. The proceedings treat the convergence of ISMAC in Computational Vision and Bioengineering technology and includes ideas and techniques like 3D sensing, human visual perception, scene understanding, human motion detection and analysis, visualization and graphical data presentation and a very wide range of sensor modalities in terms of surveillance, wearable applications, home automation etc. ISMAC-CVB is a forum for leading academic scientists, researchers and research scholars to exchange and share their experiences and research results about all aspects of computational vision and bioengineering.
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