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The International Congress on Neurotechnology, Electronics, and Informatics (NEUROTECHNIX) took place in Algarve, Portugal in September of 2013. The congress provided a meeting point of academics and clinical and engineering professionals, promoting translational discussions on how research and technology can meet the needs of clinical practitioners and patients. NEUROTECHNIX emphasized research and application of neurotechnologies to various neurological disorders, including neuromuscular diseases, Parkinson's disease, developmental disorders, dementia, epilepsy, sleep disorders, Multiple Sclerosis, neuroinfections, brain tumors, stroke, traumatic brain injuries, Cerebral Palsy, spinal cord injury and vision and hearing disorders. Authors were invited to submit innovative research work that highlighted new advancements of neurotechnology. Papers describing case studies, advanced prototypes, systems, tools and techniques and general survey papers indicating future directions were encouraged. This book contains a limited selection of extended and revised versions of the best papers presented at the congress, by regular and keynote speakers.
This book provides a comprehensive review of the chemistry and research illustrating the benefits of polyurethane for immobilizing cells, with dozens of case studies in medical devices and environmental engineering. Offers an essential resource for medical and environmental scientists Provides a multidisciplinary and lucid writing style that uses little or no jargon Extrapolates current technology into advanced areas, especially environmental remediation and medical devices Fills the gap between immobilization research and practical applications
Grids are currently used in many sectors of life sciences, including basic sciences such as genomics, proteomics, and bioinformatics. ""The Handbook of Research on Computational Grid Technologies for Life Sciences, Biomedicine, and Healthcare"" brings together state-of-the art methodologies and developments of grid technologies applied in different fields of life sciences. This ""Handbook of Research"" considers the use of grid technologies to support research and application of each information level where life science research takes place - a useful reference source for academicians, medical practitioners, and researchers involved in all areas of healthcare technologies. It includes: over 25 authoritative contributions by the world's leading experts in grid technologies for life sciences, biomedicine, and healthcare; comprehensive coverage of each specific topic, highlighting recent trends and describing the latest advances in the field; and, more than 1,000 references to existing literature and research on grid technologies for life sciences, biomedicine, and healthcare. A compendium of 230 key terms with detailed definitions, this book is organized by topic and indexed, making it a convenient method of reference for all IT/IS scholars and professionals. It features cross-referencing of key terms, figures, and information pertinent to grid technologies for life sciences, biomedicine, and healthcare.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A State-of-the-Art Guide to Biomedical Engineering and Design Fundamentals and Applications The two-volume Biomedical Engineering and Design Handbook, Second Edition offers unsurpassed coverage of the entire biomedical engineering field, including fundamental concepts, design and development processes, and applications. This landmark work contains contributions on a wide range of topics from nearly 80 leading experts at universities, medical centers, and commercial and law firms. Volume 1 focuses on the basics of biomedical engineering, including biomedical systems analysis, biomechanics of the human body, biomaterials, and bioelectronics. Filled with more than 500 detailed illustrations, this superb volume provides the foundational knowledge required to understand the design and development of innovative devices, techniques, and treatments. Volume 1 covers: Modeling and Simulation of Biomedical Systems Bioheat Transfer Physical and Flow Properties of Blood Respiratory Mechanics and Gas Exchange Biomechanics of the Respiratory Muscles Biomechanics of Human Movement Biomechanics of the Musculoskeletal System Biodynamics Bone Mechanics Finite Element Analysis Vibration, Mechanical Shock, and Impact Electromyography Biopolymers Biomedical Composites Bioceramics Cardiovascular Biomaterials Dental Materials Orthopaedic Biomaterials Biomaterials to Promote Tissue Regeneration Bioelectricity Biomedical Signal Analysis Biomedical Signal Processing Intelligent Systems and Bioengineering BioMEMS
A State-of-the-Art Guide to Biomedical Engineering and Design Fundamentals and Applications
The two-volume Biomedical Engineering and Design Handbook, Second Edition, offers unsurpassed coverage of the entire biomedical engineering field, including fundamental concepts, design and development processes, and applications. This landmark work contains contributions on a wide range of topics from nearly 80 leading experts at universities, medical centers, and commercial and law firms.
Volume 2 provides timely information on breakthrough developments in medical device design, diagnostic equipment design, surgery, rehabilitation engineering, prosthetics design, and clinical engineering. Filled with more than 400 detailed illustrations, this definitive volume examines cutting-edge design and development methods for innovative devices, techniques, and treatments.
Volume 2 covers: Medical Product DesignFDA Medical Device RequirementsCardiovascular DevicesDesign of Respiratory DevicesDesign of Artificial KidneysDesign of Controlled-Release Drug Delivery SystemsSterile Medical Device Package Development Design of Magnetic Resonance SystemsInstrumentation Design for Ultrasonic ImagingThe Principles of X-Ray Computed TomographyNuclear Medicine Imaging Instrumentation Breast Imaging SystemsSurgical Simulation TechnologiesComputer-Integrated Surgery and Medical RoboticsTechnology and DisabilitiesApplied Universal Design Design of Artificial Arms and Hands for Prosthetic Applications Design of Artificial Limbs for Lower Extremity AmputeesWear of Total Knee and Hip Joint ReplacementsHome Modification DesignIntelligent Assistive TechnologyRehabilitatorsRisk Management in HealthcareTechnology Planning for Healthcare InstitutionsHealthcare Facilities PlanningHealthcare Systems EngineeringEnclosed Habitat Life Support
A comprehensive and systematic summary on computational aspects of nanobiotechnology and its biomedical applications Over the past decade, nanoparticles have been used in the field of various diagnostic nanoplatforms, including liposomes, polymeric micelles, quantum dots, Au/Si/polymer shells, and dendrimers. Although recent data on in vivo nanoparticle drug delivery has shown remarkably improved efficacy over traditional drug delivery, there are still many challenges in the nanomedicine field. Therefore, the deep insights on computational and modeling aspects of advanced nanomaterials and nanotechnology related to the field of biomedicine are highly required. Computational Approaches in Biomedical Nano-Engineering comprehensively and systematically treats modern understanding of the nanobiotechnology and its therapeutic applications. It covers the nanomedicine, imaging, targeted therapeutic applications, and experimental results, along with modeling approaches. It presents the fundamentals on the computational and modeling aspects of advanced nanomaterials and nanotechnology specifically in the field of biomedicine, and also provides readers with inspirations for new development of diagnostic imaging and targeted curative uses. Offers complete coverage of nanobiotechnology and its many therapeutic applications Provides a very good complimentary stance to the practical side of the nanobiotechnology field Covers an incredibly topical subject that is immensely informative to many researchers, consultants, and others engaged in nanobiotechnology Computational Approaches in Biomedical Nano-Engineering is an excellent resource that will be of great interest to biotechnologists, materials scientists, bioengineers, biochemists, and chemical engineers, as well as pharmaceutical chemists.
This new work is dedicated to glasses and their variants which can be used as biomaterials to repair diseased and damaged tissues. Bio-glasses are superior to other biomaterials in many applications, such as healing bone by signaling stem cells to become bone cells.
Key features: First book on biomaterials to focus on bio-glassesEdited by a leading authority on bio-glasses trained by one of its inventors, Dr Larry HenchSupported by the International Commission on Glass (ICG)Authored by members of the ICG Biomedical Glass Committee, with the goal of creating a seamless textbookWritten in an accessible style to facilitate rapid absorption of informationCovers all types of glasses, their properties and applications, and demonstrates how glass is an attractive improvement to current proceduresOf interest to the biomedical as well as the materials science community.
The book covers all types of glasses: traditional glasses, bioactive glasses, sol-gel glasses, phosphate glasses, glass-ceramics, composites and hybrids. Alongside discussion on how bio-glasses are made, their properties, and the reasons for their use, the authors also cover their applications in dentistry, bone regeneration and tissue engineering and cancer treatment. Its solid guidance describes the steps needed to take a new material from concept to clinic, covering the essentials of patenting, scale-up, quality assurance and FDA approval.
With the advances in image guided surgery for cancer treatment, the role of image segmentation and registration has become very critical. The central engine of any image guided surgery product is its ability to quantify the organ or segment the organ whether it is a magnetic resonance imaging (MRI) and computed tomography (CT), X-ray, PET, SPECT, Ultrasound, and Molecular imaging modality. Sophisticated segmentation algorithms can help the physicians delineate better the anatomical structures present in the input images, enhance the accuracy of medical diagnosis and facilitate the best treatment planning system designs. The focus of this book in towards the state of the art techniques in the area of image segmentation and registration.
This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction of reactive oxygen species. Since oxidative stress has been suggested as a causative factor in many diseases, its prevention is vital, and there is an urgent need for oxidative stress monitoring using in vitro and in vivo models. Interdisciplinary approaches have lead to the development of various oxidative stress monitoring models for real-world clinical and biomedical applications. The development of such methods requires a broad understanding of biology, chemistry, molecular biology, immunology and microbiology. As such, the book is a valuable resource for students, researchers and clinicians interested in the fundamental as well as applied aspects of oxidative stress associated diseases.
This book is a practical guidebook in biochemistry, for medical as well as life sciences' students. The book covers reference values, sample collection procedure and detailed protocol to perform experiments. Each experiment starts with a brief introduction of the protocol, followed by specimen requirements and procedure. The procedures are presented in a very lucid manner and discuss details of calculations and clinical interpretations,The book is divided into 29 chapters, It offers references, general guidelines and abbreviations and provides principles and procedures of clinical biochemistry tests, along with their diagnostic importance.
Key Advances in Clinical Informatics: Transforming Health Care through Health Information Technology provides a state-of-the-art overview of the most current subjects in clinical informatics. Leading international authorities write short, accessible, well-referenced chapters which bring readers up-to-date with key developments and likely future advances in the relevant subject areas. This book encompasses topics such as inpatient and outpatient clinical information systems, clinical decision support systems, health information technology, genomics, mobile health, telehealth and cloud-based computing. Additionally, it discusses privacy, confidentiality and security required for health data. Edited by internationally recognized authorities in the field of clinical informatics, the book is a valuable resource for medical/nursing students, clinical informaticists, clinicians in training, practicing clinicians and allied health professionals with an interest in health informatics.
Drawing together topics from a wide range of disciplines, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine. Internationally renowned researchers showcase topics ranging from the basic physical principles of magnetism to the detection and manipulation, synthesis protocols and natural occurrence of magnetic nanoparticles. Up-to-date examples of their clinical usage and research applications in the biomedical fields of sensing by diverse magnetic detection methods, in imaging by MRI and in therapeutic strategies such as hyperthermia, are also discussed, providing a thorough introduction to this rapidly developing field. Each chapter features questions with answers, highlighted definition boxes, and numerous illustrations which help readers grasp key concepts. Mathematical tools, together with key literature references, provide a strong underpinning for the material, making it ideal for graduate students, lecturers, medical researchers and industrial scientific strategists.
With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, for example, as hydrogels, biochemical sensors, functional surfaces, and natural degradable materials. Throughout, the focus is on applications, with worked examples for training purposes as well as case studies included. The whole is rounded off with a look at future trends.
A comprehensive guide to the art and science of bioimaging data acquisition, processing and analysis Standard and Super-Resolution Bioimaging Data Analysis gets newcomers to bioimage data analysis quickly up to speed on the mathematics, statistics, computing hardware and acquisition technologies required to correctly process and document data. The past quarter century has seen remarkable progress in the field of light microscopy for biomedical science, with new imaging technologies coming on the market at an almost annual basis. Most of the data generated by these systems is image-based, and there is a significant increase in the content and throughput of these imaging systems. This, in turn, has resulted in a shift in the literature on biomedical research from descriptive to highly-quantitative. Standard and Super-Resolution Bioimaging Data Analysis satisfies the demand among students and research scientists for introductory guides to the tools for parsing and processing image data. Extremely well illustrated and including numerous examples, it clearly and accessibly explains what image data is and how to process and document it, as well as the current resources and standards in the field. * A comprehensive guide to the tools for parsing and processing image data and the resources and industry standards for the biological and biomedical sciences * Takes a practical approach to image analysis to assist scientists in ensuring scientific data are robust and reliable * Covers fundamental principles in such a way as to give beginners a sound scientific base upon which to build * Ideally suited for advanced students having only limited knowledge of the mathematics, statistics and computing required for image data analysis An entry-level text written for students and practitioners in the bioscience community, Standard and Super-Resolution Bioimaging Data Analysis de-mythologises the vast array of image analysis modalities which have come online over the past decade while schooling beginners in bioimaging principles, mathematics, technologies and standards.
The incidence of developing infection in prosthetic joints remains low after primary arthroplasty, but owing to the growing success of joint replacement surgery as a procedure to alleviate pain and improve mobility, infection numbers are increasing. The impact on the patient is immense, and surgical options are challenging. Prevention and reducing the incidence is the key to addressing this problem. Pathways in Prosthetic Joint Infection covers the most common incidences where the risk of PJI is elevated (such as following revision arthroplasty), and indicates suitable approaches to aid the improvement of outcomes. Featuring clearly-illustrated clinical cases on the typical presentation of established and latent infections, the microbiology profiles, assessment, and definitive management are all highlighted. Taking a team-based approach that includes the ortho-plastic surgery team, physiotherapists, and microbiologists, this new book provides a concise summary of the current literature and an essential overview of the management options for those with PJI. Endorsed by the Royal College of Surgeons, BAPRAS, The Vascular Society, and BASK, Pathways in Prosthetic Joint Infection is an indispensable title for all those working with patients who may face PJI.
Uniquely focusing on dynamic modeling, this volume incorporates metabolic regulation as a survival mechanism for cells, by driving metabolism through optimal investment of its resources for control of enzyme synthesis and activity. Consequently, the models have a proven record of describing various uptake patterns of mixed carbon substrates that have become significant in modern applications of biomass for the production of bioenergy. The models accurately describe dynamic behavior of microbes in nutrient environments with mixtures of complementary substrates, such as carbon and nitrogen. Modeling of large metabolic networks (including prospects for extension to genome scale) is enabled by lumped hybrid cybernetic models with an unparalleled capacity to predict dynamic behavior of knockout strains. This is an invaluable, must-have reference for bio-researchers and practicing engineers.
This book investigates the potential medical benefits natural biomaterials can offer in developing countries by analyzing the case of Bolivia. The book explores the medical and health related applications of Bolivian commodities: quinoa, barley, sugarcane, corn, sorghum and sunflower seeds. This book helps readers better understand some of the key health concerns facing countries like Bolivia and how naturally derived biomaterials and therapeutics could help substantially alleviate many of their problems.
Biomimetics, in general terms, aims at understanding biological
principles and applying them for the development of man-made
While there are many excellent texts focused on clinical medical imaging, there are few books that approach in vivo imaging technologies from the perspective of a scientist or physician-scientist using, or interested in using, these techniques in research. It is for these individuals that Essentials of In Vivo Biomedical Imaging is written. Featuring contributions from leading experts in the field, this authoritative reference text helps answer the following often-asked questions: Can imaging address my question? Which technique should I use? How does it work? What information does it provide? What are its strengths and limitations? What applications is it best suited for? How can I analyze the data? By explaining what each imaging technology can measure, describing major methods and approaches, and giving examples demonstrating the rich repertoire of modern biomedical imaging to address a wide range of morphological, functional, metabolic, and molecular parameters in a safe and noninvasive manner, Essentials of In Vivo Biomedical Imaging helps scientists and physician-scientists choose and utilize the appropriate in vivo imaging technologies and methods for their research.
This book provides readers with basic principles of the electrochemistry of the electrodes used in modern, implantable neural prostheses. The authors discuss the boundaries and conditions in which the electrodes continue to function properly for long time spans, which are required when designing neural stimulator devices for long-term in vivo applications. Two kinds of electrode materials, titanium nitride and iridium are discussed extensively, both qualitatively and quantitatively. The influence of the counter electrode on the safety margins and electrode lifetime in a two electrode system is explained. Electrode modeling is handled in a final chapter.
Revolutionary advances in imaging technology that provide high resolution, 3-D, non-invasive imaging of biological subjects have made biomedical imaging an essential tool in clinical medicine and biomedical research. Key technological advances include MRI, positron emission tomography (PET) and multidetector X-ray CT scanners. Common to all contemporary imaging modalities is the creation of digital data and pictures. The evolution from analog to digital image data is driving the rapidly expanding field of digital image analysis. Scientists from numerous disciplines now require in-depth knowledge of these complex imaging modalities. Introduction to the Science of Medical Imaging presents scientific imaging principles, introduces the major biomedical imaging modalities, reviews the basics of human and computer image analysis and provides examples of major clinical and research applications. Written by one of the world's most innovative and highly respected neuroradiologists, Introduction to the Science of Medical Imaging is a landmark text on image acquisition and interpretation.
This book offers present-day retrospectives and future perspectives on `phytobiont' studies in the context of phyto-micro restitution, filling some of the information gaps in this promising research field. It discusses several ecosystem restitution strategies using dissimilar groups of microbes alone or in association with plants, as well as advances in metagenomics technology for studying in situ micro and macro communities in contaminated soil. It addresses topics such as the status quo, and the perspectives of microbial researchers and scientists, foresters, students, environmentalists, agriculturists and professional engineers. The rising pollution levels caused by xenobiotics is one of the biggest problems of our times, and as such the book comprehensively elaborates the latest research in this field and describes how the issue can be tackled using micro-organisms. With detailed diagrams and illustrations, the book is a valuable resource for experts and novices in the field of microbial bioremediation, phyto-bioremediation and environmental microbiology
The bioelectronic nose, the device which has a similar function to the human smell sensing system, can be realized by combining the olfactory cells or receptors with nanotechnology.In the last two decades, much has been learned about the smell sensing mechanism in biological systems. With knowledge about the biological olfactory system and the techniques for the expression of biological receptor proteins, we are able to utilize biological materials and systems to mimic the biological olfactory system. In addition to the advances in biological and biotechnological area, nanotechnology has progressed to a great degree. The bioelectronic nose is a good example of the integration of biotechnology and nanotechnology. This book describes basic biological sciences of the olfactory system, biotechnology for the production of olfactory biological elements, and nanotechnology for the development of various sensing devices. The purpose of this book is to provide the reader with a concept, basic sciences, fundamental technologies, applications, and perspectives of the bioelectronic nose."
Visual Tracking in Conventional Minimally Invasive Surgery introduces the various tools and methodologies that can be used to enhance a conventional surgical setup with some degree of automation. The main focus of this book is on methods for tracking surgical tools and how they can be used to assist the surgeon during the surgical operation. Various notions associated with surgeon-computer interfaces and image-guided navigation are explored, with a range of experimental results. The book starts with some basic motivations for minimally invasive surgery and states the various distinctions between robotic and non-robotic (conventional) versions of this procedure. Common components of this type of operation are presented with a review of the literature addressing the automation aspects of such a setup. Examples of tracking results are shown for both motion and gesture recognition of surgical tools, which can be used as part of the surgeon-computer interface. In the case of marker-less tracking, where no special visual markers can be added to the surgical tools, the tracking results are divided into two types of methodology, depending on the nature and the estimate of the visual noise. Details of the tracking methods are presented using standard Kalman filters and particle filters. The last part of the book provides approaches for tracking a region on the surgical scene defined by the surgeon. Examples of how these tracking approaches can be used as part of image-guided navigation are demonstrated. This book is designed for control engineers interested in visual tracking, computer vision researchers and system designers involved with surgical automation, as well as surgeons, biomedical engineers, and robotic researchers.
The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the last 15 years the LbL technique has seen considerable developments and has now reached a point where it is beginning to find applications in bioengineering and biomedical engineering. The book gives a thorough overview of applications of the LbL technique in the context of bioengineering and biomedical engineering where the last years have witnessed tremendous progress. The first part familiarizes the reader with the specifics of cell-film interactions that need to be taken into account for successful application of the LbL method in biological environments. The second part focuses on LbL-derived small drug delivery systems and antibacterial agents, and the third part covers nano- and microcapsules as drug carriers and biosensors. The fourth and last part focuses on larger-scale biomedical applications of the LbL method such as engineered tissues and implant coatings.
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