The text discusses synthesis, processing, design, simulation and characterization of biomaterials for biomedical applications. It synergizes exploration related to various properties and functionalities in the biomedical field through extensive theoretical and experimental modeling. It further presents advanced integrated design and nonlinear simulation problems occurring in the biomedical engineering field. It will serve as an ideal reference text for senior undergraduate and graduate students, and academic researchers in fields including biomedical engineering, mechanical engineering, materials science, ergonomics, and human factors. The book: Employs a problem-solution approach, where, in each chapter, a specific biomedical engineering problem is raised and its numerical, and experimental solutions are presented Covers recent developments in biomaterials such as OPMF/KGG bio composites, PEEK-based biomaterials, PF/KGG biocomposites, oil palm mesocarp Fibre/KGG biocomposites, and polymeric resorbable materials for orthopedic, dentistry and shoulder arthroplasty applications Discusses mechanical performance and corrosive analysis of biomaterials for biomedical applications in detail Presents advanced integrated design and nonlinear simulation problems occurring in the biomedical engineering field Presents biodegradable polymers for various biomedical applications over the last decade owing to their non-corrosion in the body, biocompatibility and superior strength in growing state Synergizes exploration related to the various properties and functionalities in the biomedical field through extensive theoretical and experimental modeling

Healthcare Technology Management: A Systematic Approach offers a comprehensive description of a method for providing safe and cost effective healthcare technology management (HTM). The approach is directed to enhancing the value (benefit in relation to cost) of the medical equipment assets of healthcare organizations to best support patients, clinicians and other care providers, as well as financial stakeholders. The authors propose a management model based on interlinked strategic and operational quality cycles which, when fully realized, delivers a comprehensive and transparent methodology for implementing a HTM programme throughout a healthcare organization. The approach proposes that HTM extends beyond managing the technology in isolation to include advancing patient care through supporting the application of the technology. The book shows how to cost effectively manage medical equipment through its full life cycle, from acquisition through operational use to disposal, and to advance care, adding value to the medical equipment assets for the benefit of patients and stakeholders. This book will be of interest to practicing clinical engineers and to students and lecturers, and includes self-directed learning questions and case studies. Clinicians, Chief Executive Officers, Directors of Finance and other hospital managers with responsibility for the governance of medical equipment will also find this book of interest and value. For more information about the book, please visit the website.

Medical image analysis using advanced fuzzy set theoretic techniques is an exciting and dynamic branch of image processing. Since the introduction of fuzzy set theory, there has been an explosion of interest in advanced fuzzy set theories-such as intuitionistic fuzzy and Type II fuzzy set-that represent uncertainty in a better way. Medical Image Processing: Advanced Fuzzy Set Theoretic Techniques deals with the application of intuitionistic fuzzy and Type II fuzzy set theories for medical image analysis. Designed for graduate and doctorate students, this higher-level text: Provides a brief introduction to advanced fuzzy set theory, fuzzy/intuitionistic fuzzy aggregation operators, and distance/similarity measures Covers medical image enhancement using advanced fuzzy sets, including MATLAB (R)-based examples to increase contrast of the images Describes intuitionistic fuzzy and Type II fuzzy thresholding techniques that separate different regions/leukocyte types/abnormal lesions Demonstrates the clustering of unwanted lesions/regions even in the presence of noise by applying intuitionistic fuzzy clustering Highlights the edges of poorly illuminated images and uses intuitionistic fuzzy edge detection to find the edges of different regions Defines fuzzy mathematical morphology and explores its application using the Lukasiewicz operator, t-norms, and t-conorms Medical Image Processing: Advanced Fuzzy Set Theoretic Techniques is useful not only for students, but also for teachers, engineers, scientists, and those interested in the field of medical image analysis. A basic knowledge of fuzzy set is required, along with a solid understanding of mathematics and image processing.

The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional, more technically oriented, quality assurance activities, but also general approaches of quality and safety. It includes contributions from experts both inside and outside the field to present a global view. The task of assuring quality is no longer viewed solely as a technical, equipment-dependent endeavor. Instead, it is now recognized as depending on both the processes and the people delivering the service. Divided into seven broad categories, the text covers: Quality Management and Improvement includes discussions about lean thinking, process control, and access to services. Patient Safety and Managing Error looks at reactive and prospective error management techniques. Methods to Assure and Improve Quality deals broadly with techniques to monitor, assure, and improve quality. People and Quality focuses on human factors, changing roles, staffing, and training. Quality Assurance in Radiotherapy addresses the general issues of quality assurance with descriptions of the key systems used to plan and treat patients and includes specific recommendations on the types and frequencies of certain tests. Quality Control: Equipment and Quality Control: Patient-Specific provides explicit details of quality control relating to equipment and patient-specific issues. Recently, a transformation of quality and safety in radiotherapy has begun to take place. Among the key drivers of this transformation have been new industrial and systems engineering approaches that have come to the forefront in recent years following revelations of system failures. This book provides an approach to quality that is long needed, one that deals with both human and technical aspects that must be the part of any overall quality improvement program.

Argues that developments in biomedicine in China should be at the center of our understanding of biomedicine, not at the periphery Today China is a major player in advancing the frontiers of biomedicine, yet previous accounts have examined only whether medical ideas and institutions created in the West were successfully transferred to China. This is the firstbook to demonstrate the role China played in creating a globalized biomedicine between 1850 and 1950. This was China's "Century of Humiliation" when imperialist powers dominated China's foreign policy and economy, forcing it to join global trends that included limited public health measures in the nineteenth century and government-sponsored healthcare in the twentieth. These external pressures, combined with a vast population immiserated by imperialism and the decline of the Chinese traditional economy, created extraordinary problems for biomedicine that were both unique to China and potentially applicable to other developing nations. In this book, scholars based in China, the United States, and the United Kingdom make the case that developments in biomedicine in China such as the discovery of new diseases, the opening of the medical profession to women, the mass production of vaccines, and the delivery ofhealthcare to poor rural areas should be at the center of our understanding of biomedicine, not at the periphery. CONTRIBUTORS: Daniel Asen, Nicole Barnes, Mary Augusta Brazelton, Gao Xi , He Xiaolian, Li Shenglan, David Luesink, William H. Schneider, Shi Yan, Yu Xinzhong, DAVID LUESINK is Assistant Professor of History at Sacred Heart University. WILLIAM H. SCHNEIDER is Professor Emeritus of History and Medical Humanities at Indiana University Purdue University Indianapolis. ZHANG DAQING is Professor and Director, Institute of Medical Humanities at Peking University in Beijing.

This book introduces the new concept of "nanozyme", which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of "nanozyme".

Discover the Most Advanced Technologies in Biomagnetics Co-edited by Professor Ueno, a leader in the biomagnetics field for over 40 years, Biomagnetics: Principles and Applications of Biomagnetic Stimulation and Imaging explains the physical principles of biomagnetic stimulation and imaging and explores applications of the latest techniques in neuroscience, clinical medicine, and healthcare. The book shows you how the techniques are used in hospitals and why they are so promising. A brief overview of recent research trends in biomagnetics provides you with an up-to-date, informative guide to explore further in this field. The book focuses on three important areas: Magnetic nerve stimulation and transcranial magnetic stimulation Biomagnetic measurements and imaging of the human brain by advanced technologies of magnetoencephalography and MRI Biomagnetic approaches to potential treatments of cancers, pains, and other neurological and psychiatric diseases, such as Alzheimer's disease and depression These core areas of the book were developed from the editors' prestigious graduate-level courses in biomedical engineering. The text also discusses biomagnetic approaches to advanced medicine, including regenerative and rehabilitation medicine.

This three-volume set explores Problems and Solutions in Medical Physics. These invaluable study guides should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. Volume one explores Diagnostic Imaging Physics and contains problems and solutions on key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Volume two explores Nuclear Medicine and contains problems and solutions on radioactivity and nuclear transformation, radionuclide production and radiopharmaceuticals, non-imaging detectors and counters, instrumentation for gamma imaging, SPECT and PET/CT, imaging techniques, radionuclide therapy, internal radiation dosimetry, and quality control and radiation protection in nuclear medicine. Volume three explores Radiotherapy and contains problems and solutions on external beam therapy equipment, photon beam physics, radiation dosimetry, treatment planning for external beam radiotherapy, and external beam commissioning and quality assurance. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

This three-volume set explores Problems and Solutions in Medical Physics. These invaluable study guides should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. Volume one explores Diagnostic Imaging Physics and contains problems and solutions on key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Volume two explores Nuclear Medicine and contains problems and solutions on radioactivity and nuclear transformation, radionuclide production and radiopharmaceuticals, non-imaging detectors and counters, instrumentation for gamma imaging, SPECT and PET/CT, imaging techniques, radionuclide therapy, internal radiation dosimetry, and quality control and radiation protection in nuclear medicine. Volume three explores Radiotherapy and contains problems and solutions on external beam therapy equipment, photon beam physics, radiation dosimetry, treatment planning for external beam radiotherapy, and external beam commissioning and quality assurance. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

Biomass and Carbon Fuels in Metallurgy presents contemporary and new insights into the use of carbonaceous (Biomass) fuels in the metallurgical sector. The authors describe application of these fuels in different technological processes to produce pig iron, steel and ferroalloys. Emphasis is placed on biomass and its metallurgical utilization. Coverage includes the specification of fuels, their classification and the characteristics of their basic properties. The use of carbonaceous fuels in the production of various kinds of agglomerates (ferriferous, manganese and metalized) is also covered. Key Features: Provides a comprehensive view of carbonaceous fuels in various metallurgy processes Details experiments conducted on the use of traditional and alternative (biomass) carbonaceous fuels for the production of agglomerates. Demonstrates that the energy potential of biomass can also be successfully used in pyrometallurgical processes Describes applications of biomass-based fuels in different technological processes for the production of pig iron, steel and ferroalloys. Coverage includes the specification of fuels, their classification and the characteristics of their basic properties.

Two of the most important yet often overlooked aspects of a medical device are its usability and accessibility. This is important not only for health care providers, but also for older patients and users with disabilities or activity limitations. Medical Instrumentation: Accessibility and Usability Considerations focuses on how lack of usability and accessibility pose problems for designers and users of medical devices, and how to overcome these limitations. Divided into five broad sections, the book first addresses the nature and extent of the problem by identifying access barriers, human factors, and policy issues focused on the existing infrastructure. The subsequent sections examine responses to the problem, beginning with tools for usability and accessibility analysis and principles of design for medical instrumentation. Building on this foundation, the third section focuses on recommendations for design guidelines while the fourth section explores emerging trends and future technologies for improving medical device usability. The final section outlines key challenges, knowledge gaps, and recommendations from accomplished experts in the field presented at the recent Workshop on Accessible Interfaces for Medical Instrumentation. Integrating expert perspectives from a wide array of disciplines, Medical Instrumentation traces a clear roadmap for improving accessibility and usability for a variety of stakeholders and provides the tools necessary to follow it.

Biomimetics is the idea of creating new technologies abstracted from what we find in biology. Ocean Innovation: Biomimetics Beneath the Waves seeks that technological inspiration from the rich biodiversity of marine organisms. Bringing both a biological and engineering perspective to the biomimetic potential of oceanic organisms, this richly illustrated book investigates questions such as: How can we mimic the sensory systems of sea creatures like sharks, sea turtles, and lobsters to improve our ability to navigate underwater? What can we do to afford humans the opportunity to go unnoticed by marine life? How can we diffuse oxygen from water to enable deep diving without the risk of decompression sickness? Each chapter explores an area where we, as divers and technologists, can benefit from understanding how animals survive in the sea, presenting case studies that demonstrate how natural solutions can be applied to mankind's engineering challenges.

This book covers two most important applications of smart sensors, namely bio-health sensing and environmental monitoring. The approach taken is holistic and covers the complete scope of the subject matter from the principles of the sensing mechanism, through device physics, circuit and system implementation techniques, and energy issues to wireless connectivity solutions. It is written at a level suitable mainly for post-graduate level researchers interested in practical applications. The chapters are independent but complementary to each other, and the book works within the wider perspective of essential smart sensors for the Internet of Things (IoT). This is the second of three books based on the Integrated Smart Sensors research project, which describe the development of innovative devices, circuits, and system-level enabling technologies. The aim of the project was to develop common platforms on which various devices and sensors can be loaded, and to create systems offering significant improvements in information processing speed, energy usage, and size. This book contains substantial reference lists and over 150 figures, introducing the reader to the subject in a tutorial style whilst also addressing state-of-the-art research results, allowing it to be used as a guide for starting researchers.

As one of the most important tasks in biomedical imaging, image segmentation provides the foundation for quantitative reasoning and diagnostic techniques. A large variety of different imaging techniques, each with its own physical principle and characteristics (e.g., noise modeling), often requires modality-specific algorithmic treatment. In recent years, substantial progress has been made to biomedical image segmentation. Biomedical image segmentation is characterized by several specific factors. This book presents an overview of the advanced segmentation algorithms and their applications.

Tissue stem cells and their medical applications have become a major focus of research over the past decade. With 16 full-color illustrations, this reference provides a thorough and up-to-date overview of the current and emerging technologies for stem cell research and transplantation. Divided into three sections covering general issues, adult stem cells within specific tissues, and clinical applications, this source studies advances in bone marrow transplantation, cancer development modeling, tumor analysis, and gene therapy.

Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa

Convenient - everything at your fingertips, for speedy access in the emergency department, on the ward and in the clinic. Portable - actually fits in a pocket. Illustrated - plentiful photographs and explanatory line diagrams support and enhance the text. Tailored - written specifically with the less experienced practitioner in mind.

Choice Recommended Title, January 2021 This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective

Biomedical nanotechnology is one of the fastest-growing fields of research across the globe. However, even the most promising technologies may never realize their full potential if public and political opinions are galvanized against them, a situation clearly evident in such controversial fields as cloning and stem cell research. Biomedical Nanotechnology presents state-of-the-art research in the field and also considers the socio-political risks and perceptions of this important science. Contributed by prominent experts in this expansive and interdisciplinary field, Biomedical Nanotechnology examines developments in three sub-fields: nanodrugs and drug delivery; prostheses and implants; and diagnostics and screening technologies. The authors compare new capabilities introduced by nanotechnology to traditional methods of release, target, and controlled drug delivery in the body. They also consider the challenge of understanding and controlling the biological processes involved upon implantation and discuss nanoscale sensors for biological chemical detection and biodefense. The book concludes with individual chapters devoted to the social and economic context of nanotechnologies and to their potential risks and possible solutions. By outlining cutting-edge research in the context of pressing global medical needs and potential risks, this authoritative reference supplies a holistic treatment of biomedical nanotechnology that enables us to understand its implications and decide the best way to move forward.

Given silicon's versatile material properties, use of low-cost silicon photonics continues to move beyond light-speed data transmission through fiber-optic cables and computer chips. Its application has also evolved from the device to the integrated-system level. A timely overview of this impressive growth, Silicon Photonics for Telecommunications and Biomedicine summarizes state-of-the-art developments in a wide range of areas, including optical communications, wireless technologies, and biomedical applications of silicon photonics. With contributions from world experts, this reference guides readers through fundamental principles and focuses on crucial advances in making commercial use of silicon photonics a viable reality in the telecom and biomedical industries. Taking into account existing and anticipated industrial directions, the book balances coverage of theory and practical experimental research to explore solutions for obstacles to the viable commercialization of silicon photonics. The book's special features include: A section on silicon plasmonic waveguides Detailed coverage of novel III-V applications A chapter on 3D integration Discussion of applications for energy harvesting/photovoltaics This book reviews the most important technological trends and challenges. It presents topics involving major silicon photonics applications in telecommunications, high-power photonics, and biomedicine. It includes discussion of silicon plasmonic waveguides, piezoelectric tuning of silicon's optical properties, and applications of two-photon absorption. Expert authors with industry research experience examine the challenge of hybridizing III-V compound semiconductors on silicon to achieve monolithic light sources. They also address economic compatibility and heat dissipation issues in CMOS chips, challenges in designing electronic photonics in

From cell phones to treating cancer, EM energy plays a part in many of the innovations that we take for granted everyday. A basic force of nature, like nuclear energy or gravity, this energy can be harnessed and used, but still holds the potential to be harmful. The question remains, how safe are EM products? Bioeffects and Therapeutic Applications of Electromagnetic Energy provides a review of cutting-edge research in EM health effects and EM therapy along with emerging areas of bioengineering and biomedical engineering. The book allows you to * Understand the necessary EM theory in the context of its interaction with the human body * Review cutting-edge research on EM health effects and EM therapy * Explore techniques developed to ensure adequate EM and thermal dosimetry required for health effects and thermal therapy * Strengthen your understanding of the rapidly emerging areas of bioengineering and biomedical engineering Taking a transdisciplinary approach drawn from several intellectual streams that include physics, epidemiology, medicine, environment, risk assessment, and various disciplines of engineering, this book ventures into the conflicting studies to access research on bioeffects and therapeutic applications of EM energy. It is the only resource currently available that covers bioeffects and risk assessment of both extremely low frequency (ELF) fields and radiofrequency radiation (RFR) along with the recent developments in thermal therapy and imaging techniques.

This book systematically introduces the bionic nature of force sensing and control, the biomechanical principle on mechanism of force generation and control of skeletal muscle, and related applications in robotic exoskeleton. The book focuses on three main aspects: muscle force generation principle and biomechanical model, exoskeleton robot technology based on skeletal muscle biomechanical model, and SMA-based bionic skeletal muscle technology. This comprehensive and in-depth book presents the author's research experience and achievements of many years to readers in an effort to promote academic exchanges in this field. About the Author Yuehong Yin received his B.E. , M.S. and Ph.D. degrees from Nanjing University of Aeronautics and Astronautics, Nanjing, in 1990, 1995 and 1997, respectively, all in mechanical engineering. From December 1997 to December 1999, he was a Postdoctoral Fellow with Zhejiang University, Hangzhou, China, where he became an Associate Professor in July 1999. Since December 1999, he has been with the Robotics Institute, Shanghai Jiao Tong University, Shanghai, China, where he became a Professor and a Tenure Professor in December 2005 and January 2016, respectively. His research interests include robotics, force control, exoskeleton robot, molecular motor, artificial limb, robotic assembly, reconfigurable assembly system, and augmented reality. Dr. Yin is a fellow of the International Academy of Production Engineering (CIRP).

This volume presents pedagogical content to understand theoretical and practical aspects of diagnostic imaging techniques. It provides insights to current practices, and also discusses specific practical features like radiation exposure, radiation sensitivity, signal penetration, tissue interaction, and signal confinement with reference to individual imaging techniques. It also covers relatively less common imaging methods in addition to the established ones. It serves as a reference for researchers and students working in the field of medical, biomedical science, physics, and instrumentation. Key Features * Focusses on the clinical applications while ensuring a steady understanding of the underlying science * Follows a bottom-up approach to cover the theory, calculations, and modalities to aid students and researchers in biomedical imaging, radiology and instrumentation * Covers unique concepts of nanoparticle applications along with ethical issues in medical imaging

This volume presents pedagogical content to understand theoretical and practical aspects of diagnostic imaging techniques. It provides insights to current practices, and also discusses specific practical features like radiation exposure, radiation sensitivity, signal penetration, tissue interaction, and signal confinement with reference to individual imaging techniques. It also covers relatively less common imaging methods in addition to the established ones. It serves as a reference for researchers and students working in the field of medical, biomedical science, physics, and instrumentation. Key Features * Focusses on the clinical applications while ensuring a steady understanding of the underlying science * Follows a bottom-up approach to cover the theory, calculations, and modalities to aid students and researchers in biomedical imaging, radiology and instrumentation * Covers unique concepts of nanoparticle applications along with ethical issues in medical imaging

Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning of bio-implant interface reactions will have a tremendous impact on future design and prospects of implant treatments. Bio-Implant Interface: Improving Biomaterials and Tissue Reactions brings together a remarkable panel of scientists to present the state-of-the-art in our understanding of interactions at the interface between biomaterials and living tissue. Much of the focus is on the importance of the implant surface's topography and chemistry to its interaction with the biological environment. Biomineralization along with the biological content of the interface and its role in directing cellular response along desired pathways also receive particular attention. The pursuit of new and better designs for improved biocompatibility and patient response to implants continues to challenge clinicians and scientists alike. This book offers a unique opportunity to bring yourself up-to-date on recent advances in the field and new strategies for controlling the bio-implant interface.