Excel in your career as an occupation therapist with the expert information and easy-to-understand presentation in "Orthotic Intervention for the Hand and Upper Extremity: Splinting Principles and Process, 2nd Edition. "This proven book provides orthosis patterns for most upper extremity diagnoses and provides the information you need to make an informed decision about whether the best solution for a patient is to fabricate a thermoplastic or neoprene splint, or to cast, tape, or choose an over-the-counter solution. This detailed and easy-to-use reference demonstrates splint fabrication techniques and related interventions, highlights anatomical and biomechanical principles, discusses associated indications and precautions, details common orthotic interventions, and provides an overview of popular taping methods.

• Master key concepts and skills with pattern descriptions and photographs for each intervention, along with "Clinical Pearls," and "Pattern Pearls" that provide fabrication and orthosis modification tips, as well as insight for improving cost containment and maximizing time efficiency.
• Apply concepts to the clinical experience with case studies that stimulate clinical reasoning and help you synthesize text information.
• Find the information you need fast with lists of splints by name and by diagnosis in the index.
• See how research informs practice with evidence-based examples.
• Prepare for practice with consistent use of ASHT orthotics nomenclature throughout the book.

Rapid developments have taken place in biological/biomedical measurement and imaging technologies as well as in computer analysis and information technologies. The increase in data obtained with such technologies invites the reader into a virtual world that represents realistic biological tissue or organ structures in digital form and allows for simulation and what is called "in silico medicine." This volume is the third in a textbook series and covers both the basics of continuum mechanics of biosolids and biofluids and the theoretical core of computational methods for continuum mechanics analyses. Several biomechanics problems are provided for better understanding of computational modeling and analysis. Topics include the mechanics of solid and fluid bodies, fundamental characteristics of biosolids and biofluids, computational methods in biomechanics analysis/simulation, practical problems in orthopedic biomechanics, dental biomechanics, ophthalmic biomechanics, cardiovascular biomechanics, hemodynamics, cell mechanics, and model-, rule-, and image-based methods in computational biomechanics analysis and simulation. The book is an excellent resource for graduate school-level engineering students and young researchers in bioengineering and biomedicine.

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physics principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions.

Many universities now offer a course in biomedical optics, but lack a textbook specifically addressing the topic. Intended to fill this gap, An Introduction to Biomedical Optics is the first comprehensive, introductory text describing both diagnostic and therapeutic optical methods in medicine. It provides the fundamental background needed for graduate students in biomedical and electrical engineering, physics, biology, and medicine to learn about several biomedical optics issues. The textbook is divided into three main sections: general optics theory, therapeutic applications of light, and diagnostic optical methods. Each chapter has different levels of detail to build students' knowledge from one level to the next. The first section covers the history of optics theory and the basic science behind light-tissue interactions. It also introduces the relevant approaches and approximations used to describe light propagation in turbid biological media. In the second section, the authors look more closely at light-tissue interactions and their applications in different medical areas, such as wound healing and tissue welding. The final section examines the various diagnostic methods that are employed using optical techniques. Throughout the text, the authors employ numerical examples of clinical and research requirements. Fulfilling the need for a concise biomedical optics textbook, An Introduction to Biomedical Optics addresses the theory and applications of this growing field.

Biology is a critical application area for engineering analysis and design, and students in engineering programs as well as ecologists and environmentalists must be well-versed in the fundamentals of biology as they relate to their field. Biology for Engineers, Second Edition is an introductory text that minimizes unnecessary memorization of connections and classifications and instead emphasizes concepts, technology, and the utilization of living things. Whether students are headed toward a bio-related engineering degree or one of the more traditional majors, biology is so important that all engineering students should know how living things work and act. Emphasizing the ever-present interactions between a biological unit and its physical, chemical, and biological environments, the book provides ample instruction on the basics of physics, chemistry, mathematics, and engineering through a systems approach. It brings together all the concepts one needs to understand the role of biology in modern technology. Classroom-tested at the University of Maryland, this comprehensive text introduces concepts and terminology needed to understand more advanced biology literature. Filled with practical detailed examples, the book presents: Presents scientific principles relevant to biology that all engineers, ecologists and environmentalists must know A discussion of biological responses from the perspective of a broad range of fields such as psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine Includes end of chapter questions to test comprehension Provides updated material to reflect the latest research developments such as CRISPR. Introduces over 150 interesting application examples, incorporating a number of different engineering disciplines. Ties biological systems properties and behaviors to foundational sciences such as engineering sciences, chemistry, etc.

This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: * semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors * impedimetric biosensors using planar and 3D electrodes * nanocavity and solid-state nanopore devices * carbon nanotube and graphene/graphene oxide biosensors * electrochemical biosensors using molecularly imprinted polymers * biomimetic sensors based on acoustic signal transduction * enzyme logic systems and digital biosensors based on the biocomputing concept * heat-transfer as a novel transducer principle * ultrasensitive surface plasmon resonance biosensors * magnetic biosensors and magnetic imaging devices

Encyclopedia of Biomedical Engineering is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers.

Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge.

How does one deal with a moving control volume? What is the best way to make a complex biological transport problem tractable? Which principles need to be applied to solve a given problem? How do you know if your answer makes sense? This unique resource provides over two hundred well-tested biomedical engineering problems that can be used as classroom and homework assignments, quiz material and exam questions. Questions are drawn from a range of topics, covering fluid mechanics, mass transfer and heat transfer applications. Driven by the philosophy that mastery of biotransport is learned by practice, these problems aid students in developing the key skills of determining which principles to apply and how to apply them. Each chapter starts with basic problems and progresses to more difficult questions. Lists of material properties, governing equations and charts provided in the appendices make this a fully self-contained work. Solutions are provided online for instructors.

This book offers a clear, yet comprehensive overview of the role of robots in our society. It especially focuses on the interaction between humans and robots, and on the social and political aspects of the integration of robots with humans, in their everyday life, both in the private and working sphere alike. Based on the lessons held by the author at "Scuola di Politiche" (transl. School of Political Sciences), this self-contained book mainly addresses an educated, though not-specialist, audience.

This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.

This monograph addresses an innovative autologous muscle-derived stem cell therapy for urinary incontinence in women. It provides a detailed overview of studies and research projects on the use of stem cells for the treatment of urinary incontinence. It provides updated information about this condition for the era of regenerative medicine, making it a valuable resource for both students and physicians.

In Research as Development, Salla Sariola and Bob Simpson show how international collaboration operates in a setting that is typically portrayed as "resource-poor" and "scientifically lagging." Based on their long-term fieldwork in Sri Lanka, Sariola and Simpson bring into clear ethnographic focus the ways international scientific collaborations feature prominently in the pursuit of global health in which research operates "as" development and not merely "for" it. The authors follow the design, inception, and practice of two clinical trials: one a global health charity funded trial and the other a pharmaceutical industry-sponsored trial. Research as Development situates these two trials within their historical, political and cultural contexts and thus counters the idea that local actors are merely passive recipients of new technical and scientific rationalities. While social studies of clinical trials are beginning to be an established niche in academic writing, Research as Development helps fill important gaps in the literature through its examination of clinical research situated in cultures in low-income settings. Research as Development is noteworthy for the way it highlights the critical and creative role that local researchers play in establishing international collaborations and making them work into locally viable forms. The volume shows how these clinical and research interactions bring about changes in culture, technologies and expertise in Sri Lanka, contexts that have not previously been written about in any detail.

In this book, we approach neurophysiology at the interface of neurology and clinical neurophysiology. The medical disciplines of the nervous system, n- rology and clinical neurophysiology, rest heavily on other sciences, notably cellular biology, neuro-anatomy, neuro-physiology, applied physics and ma- ematical biology. Existing medical textbooks on neurophysiology, neurology and clinical neurophysiology are an excellent source of the phenomenology of various principles and diseases. Here, we choose to elucidate some of the under- ing physiological, physical processes and experimental methods, intended for a broad audience - medical residents and students, as well as students in the emerging area of medical technical sciences. We feel that a good understanding of fundamentals may signi?cantly - hance insight into various aspects of clinical neurology and clinical neu- physiology. This book, therefore, is focused on a selection of clinical signs and symptoms to highlight basic principles of neurology, (neuro-)physiology and neuroanatomy. While we believe this text to be of interest to medical students or residents in neurology or clinical neurophysiology, we speci?cally aim at students - terested in contributing to new developments and innovations in neurology and clinical neurophysiology. These students are involved with patients, even though they are not trained for routine patient care.

Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment.

Definitions of Biomaterials for the Twenty-First Century is a review of key, critical biomaterial terms and definitions endorsed by the International Union of Societies for Biomaterials Science and Engineering. The topics and definitions discussed include those in general biomaterials and applications, biocompatibility, implantable and interventional devices, drug delivery systems, regenerative medicine and emerging biomaterials. The book reviews the discussion of these terms by leaders in the global biomaterials community and summarizes the agreed upon definitions.

High-Density Integrated Electrocortical Neural Interfaces provides a basic understanding, design strategies and implementation applications for electrocortical neural interfaces with a focus on integrated circuit design technologies. A wide variety of topics associated with the design and application of electrocortical neural implants are covered in this book. Written by leading experts in the field-Dr. Sohmyung Ha and Dr. Gert Cauwenberghs-the book discusses basic principles and practical design strategies of electrocorticography, electrode interfaces, signal acquisition, power delivery, data communication, and stimulation. In addition, an overview and critical review of the state-of-the-art research is included. These methodologies present a path towards the development of minimally invasive brain-computer interfaces capable of resolving microscale neural activity with wide-ranging coverage across the cortical surface.

This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.

Disaster Epidemiology: Methods and Applications applies the core methods of epidemiological research and practice to the assessment of the short- and long-term health effects of disasters. The persistent movement of people and economic development to regions vulnerable to natural disasters, as well as new vulnerabilities related to environmental, technological, and terrorism incidents, means that in spite of large global efforts to reduce the impacts and costs of disasters, average annual expenditures to fund rebuilding from catastrophic losses is rising faster than either population or the gross world product. Improving the resilience of individuals and communities to these natural and technological disasters, climate change, and other natural and manmade stressors is one of the grand challenges of the 21st century. This book provides a guide to disaster epidemiology methods, supported with applications from practice. It helps researchers, public health practitioners, and governmental policy makers to better quantify the impacts of disaster on the health of individuals and communities to enhance resilience to future disasters. Disaster Epidemiology: Methods and Applications explains how public health surveillance, rapid assessments, and other epidemiologic studies can be conducted in the post-disaster setting to prevent injury, illness, or death; provide accurate and timely information for decisions makers; and improve prevention and mitigation strategies for future disasters. These methods can also be applied to the study of other types of public health emergencies, such as infectious outbreaks, emerging and re-emerging diseases, and refugee health. This book gives both the public health practitioner and researcher the tools they need to conduct epidemiological studies in a disaster setting and can be used as a reference or as part of a course.

This book highlights the development of a functional nucleic acid based biosensor detection method in the context of food safety. Although there have been major advances in food processing technology in both developed and developing countries, food safety assurance systems are generally becoming more stringent, in response to growing (both real and perceived) food safety problems. These problems are due in part to foodborne microorganisms, heavy metals, and small chemical molecules (biological toxins, pesticide residues, and veterinary drug residues), etc. In addition, the nucleic acid biomarkers (DNA methylation, microRNA, and circRNA) induced by these risk factors are also closely related to food safety. Accordingly, this book offers a brief guide to targets and strategies in functional nucleic acid based biosensors for food safety detection. Divided into several chapters that focus on various respective targets, it will be a valuable resource for students and researchers in the fields of biosensor detection, food science etc.

Bio-inspired concepts for biomedical engineering are at the forefront of tissue engineering and regenerative medicine. Providing a comprehensive overview of the latest advances and techniques in the field, Bio-inspired Materials for Biomedical Engineering demonstrates the dramatic clinical breakthroughs that have been made in engineering all four of the major tissue types and modulating the immune system. Written by prominent leaders in the fields of materials engineering, chemical engineering, cell biology, and regenerative medicine, this groundbreaking text provides scientists, professors, postdocs, and graduate students with the dramatic clinical breakthroughs related to tissue engineering applications.

This book offers a complete overview of photonic-enhanced materials from material development to a final photonic biomedical application. It includes fundamental, applied, and industrial photonics. The authors cover synthesis, the modification and the processing of a variety of (bio)polymers including thermoplasts (e.g. polyesters) and hydrogels (e.g. proteins and polysaccharides) for a plethora of applications in the field of optics and regenerative medicine.

This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level - e.g. different omics data at the molecular level - but also data from different levels - the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

This book discusses a number of case studies to showcase the translation of research concepts to lab-scale materials development for biomedical applications. The book intends to motivate active researchers to develop new generation biomaterials. This book is meant for readers, who are already familiar with the broad area of biomaterials. The book introduces readers to the field of additive manufacturing of biomaterials and teaches them how to extend this innovative processing approach to a variety of biomaterials for musculoskeletal applications. It covers both in vitro and in vivo biocompatibility and toxicity assessment for a broad range of biomaterials in the context of bone tissue engineering. It works to sensitise researchers in the field of translational biomedical engineering on the importance of clinical trials and discusses the challenges ahead in this important field of research. This book will be useful to clinicians, professionals and researchers alike.