Advances in Biomedical Polymers and Composites: Materials and Applications is a comprehensive guide to polymers and polymer composites for biomedical applications, bringing together detailed information on their preparation, properties, cutting-edge technologies, innovative materials and key application areas. Sections introduce polymers and composites in biomedical applications and cover characterization techniques, preparation and properties of composites and gel-based systems. Innovative technologies and instruments used in the fabrication of polymer composites for biomedical applications are then presented in detail, including 3D bioprinting, 4D printing, electrospinning, stimuli-responsive polymers and quantum dots. This is a valuable resource for anyone looking to gain a broader understanding of polymers and composites for biomedical applications. In addition, it is ideal for readers who want to conduct interdisciplinary research or explore new avenues for research and development.

Design and Applications of Theranostic Nanomedicines reviews the composition and design of various nanomedicines for theranostic applications, helping readers to make informed decisions when exploring novel treatments for disease. This book introduces readers to theranostic nanostructures as nanomedicines, beginning with a balanced look at the associated challenges, costs and benefits. The next section goes on to detail a range of different theranostic nanomedicines and their design, from nanodispersions and nanogels to exosomes and polymeric micelles. A variety of applications is covered, including in the treatment of pulmonary diseases, neurological disorders, cancers and more. The book also takes a look at the toxicological implications of nanotheranostics, an important aspect of any therapy or treatment. Design and Applications of Theranostic Nanomedicines provides a snapshot of the state-of-the-art, and will be of use to materials scientists, biomedical engineers and pharmaceutical scientists with an interest in nanotechnology and theranostics.

Engineered Nanostructures for Therapeutics and Biomedical Applications offers a single reference for a diverse biomedical readership to learn about the application of nanotechnology in biomedicine and biomedical engineering, from past developments to current research and future prospects. This book sets out a broad selection of biomedical and therapeutic applications for nanostructures, including bioimaging, nanorobotics, orthopedics, and tissue engineering, offering a useful, multidisciplinary approach. Each chapter discusses challenges faced in each discipline, including limiting factors, biocompatibility, and toxicity, thus enabling the reader to make informed decisions in their research. This book is a comprehensive, broad overview of the role and significance of nanomaterials and their composites that also includes discussions of key aspects in the field of biomedicine. It will be of significant interest to academics and researchers in materials science and engineering, biomedicine and biomedical engineering, chemical engineering, pharmaceutics, bioimaging, and nanorobotics.

Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles. Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles - such as mucosal and transdermal - and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation.

Nature-Inspired Optimization Algorithms, Second Edition provides an introduction to all major nature-inspired algorithms for optimization. The book's unified approach, balancing algorithm introduction, theoretical background and practical implementation, complements extensive literature with case studies to illustrate how these algorithms work. Topics include particle swarm optimization, ant and bee algorithms, simulated annealing, cuckoo search, firefly algorithm, bat algorithm, flower algorithm, harmony search, algorithm analysis, constraint handling, hybrid methods, parameter tuning and control, and multi-objective optimization. This book can serve as an introductory book for graduates, for lecturers in computer science, engineering and natural sciences, and as a source of inspiration for new applications.

Natural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage on the development and application of natural polymers in wound healing and repair, including fundamental concepts, traditional approaches, cutting-edge methods and emerging trends. The application of natural polymers has evolved from their use in the simplest wound management material, to drug eluting matrices, to cell-laden constructs, and to 3D bio-printed skin equivalents. This book reflects the remarkable progress that has been made in recent years in this innovative field. This is an essential resource for researchers, scientists, and advanced students across polymer science, biomaterials, bio-based and sustainable materials, biomedicine, biomedical engineering, pharmaceuticals, and materials science and engineering. It will also be valuable to R&D professionals, scientists, technologists and all those working in a medical setting who are interested in the latest developments in advanced materials for wound management, healing and repair.

Nanobioanalytical Approaches to Medical Diagnostics reviews a range of nanobiomaterials and bioanalytical nano-devices for medical diagnostics. Nanobiomaterials and nano-devices are used in various bioanalytical and biochemical systems to provide real-time, point-of-care diagnostics. The specialized properties of nanoparticles allow them to be engineered and adapted to produce the required effect within a bioanalytical or biochemical system - offering targeted and detailed diagnostic results in a range of biomedical applications. This book covers both traditional biochemical and modern, combined nano-approaches to medical diagnostics. Chapters detail a range of in vitro, in vivo and ex vivo models for nanobioanalytics, including DNA and peptide-based, erythrocyte, microfluidic and more. In addition, sections also look at various different medical diagnostic applications, such as in cancer detection, infectious disease diagnosis and blood glucose sensing.

Biomedical Engineering Applications for People with Disabilities and the Elderly in the COVID-19 Pandemic and Beyond presents biomedical engineering applications used to manage people's disabilities and care for the elderly to improve their quality of life and extend life expectancy. This edited book covers all aspects of assistive technologies, including the Internet of Things (IoT), telemedicine, e-Health, m-Health, smart sensors, robotics, devices for rehabilitation, and "serious" games. This book will prove useful for bioengineers, computer science undergraduate and postgraduate students, researchers, practitioners, biomedical engineering students, healthcare workers, and medical doctors. This volume introduces recent advances in biomaterials, sensors, cellular engineering, biomedical devices, nanotechnology, and biomechanics applied in caring for the elderly and people with disabilities. The unique focus of this book is on the needs of this user base during emergency and disaster situations. The content includes risk reduction, emergency planning, response, disaster recovery, and needs assessment. This book offers readers multiple perspectives on a wide range of topics from a variety of disciplines. This book answers two key questions: What challenges will the elderly and people with disabilities face during a pandemic? How can new (or emerging) advances in biomedical engineering help with these challenges?

Multi-Chaos, Fractal and Multi-Fractional Artificial Intelligence of Different Complex Systems addresses different uncertain processes inherent in the complex systems, attempting to provide global and robust optimized solutions distinctively through multifarious methods, technical analyses, modeling, optimization processes, numerical simulations, case studies as well as applications including theoretical aspects of complexity. Foregrounding Multi-chaos, Fractal and Multi-fractional in the era of Artificial Intelligence (AI), the edited book deals with multi- chaos, fractal, multifractional, fractional calculus, fractional operators, quantum, wavelet, entropy-based applications, artificial intelligence, mathematics-informed and data driven processes aside from the means of modelling, and simulations for the solution of multifaceted problems characterized by nonlinearity, non-regularity and self-similarity, frequently encountered in different complex systems. The fundamental interacting components underlying complexity, complexity thinking, processes and theory along with computational processes and technologies, with machine learning as the core component of AI demonstrate the enabling of complex data to augment some critical human skills. Appealing to an interdisciplinary network of scientists and researchers to disseminate the theory and application in medicine, neurology, mathematics, physics, biology, chemistry, information theory, engineering, computer science, social sciences and other far-reaching domains, the overarching aim is to empower out-of-the-box thinking through multifarious methods, directed towards paradoxical situations, uncertain processes, chaotic, transient and nonlinear dynamics of complex systems.

Immunomodulatory Effects of Nanomaterials: Assessment and Analysis provides an overview of the modulatory impact of nanomaterials on the immune system, as well as evaluative and analytical methods for assessing effects. Sections cover a range of common nanomaterials for biomedical use and how different properties can elicit varied responses from the immune system. The immunomodulatory effects of these materials are then discussed, with coverage on adverse and/or toxic effects on the immune system, as well as desired modulatory effects to improve efficacy of applied therapeutics. Readers will also learn about the best evaluation methods for immunomodulatory effects of nanomaterials and associated risks. This book is a useful reference for academics and researchers with an interest in immunology, but it is also idea for those working in the fields of materials science, biomedical engineering, pharmaceutical science, immunology and toxicology.

Advances in Cardiovascular Technology: New Devices and Concepts is a comprehensive reference for cardiovascular devices of all types. For engineers, this book provides a basic understanding of underlying pathologies and their prevalence/incidence. It also covers what devices are available, how they are clinically used, and their impact on pathophysiology. In addition, the book presents the constraints imposed on device design and manufacture by the environment in which it is used (e.g., exposure to tissues within the body, blood in particular) and the primary requirements for each specific type of device, including its durability and resistance to fatigue. For clinicians, this book contains information on primary engineering challenges, the types of devices available, their advantages and disadvantages, and the (current and emerging) tools and materials available to device designers.

Biomaterials for Angiogenesis and Vasculogenesis covers the application of materials designed to encourage new blood vessel formation. Angiogenesis and vasculogenesis play an important role in tissue engineering and regenerative medicine research by promoting vascular networks inside engineered tissues and thereby increasing tissue healing and regeneration. However, researchers are faced with the challenge of finding suitable materials for improving angiogenesis and vascular formation in assays. This book reviews a broad range of biomaterials for the promotion of blood vessel genesis, from polymers and bioactive glass, to nanomaterial scaffolds and 3D angiogenic constructs. In addition, the book covers a variety of applications for biomaterials in tissue repair and regeneration, including cardiovascular regeneration, liver tissue engineering and much more. It will serve as a detailed reference for researchers in academia and industry, working in the fields of biomedical science and engineering, materials science, regenerative medicine and translational medicine.

Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in healthcare and biomedicine. The book provides a fundamental overview of polymers and processing technologies to allow clinical scientists to explore the use of these polymers in alternative applications. A wide variety of healthcare applications are covered, including treatment for autoimmune diseases and bacterial infections, tissue engineering, gene delivery, wound dressing, and more. The book provides a core introductory text for clinical and materials scientists new to the area of polymeric biomaterials. This book will prove useful to academics and researchers in materials science, biomedical engineering, clinical science and pharmaceutical science.

Emerging Nanomedicines for Diabetes Mellitus Theranostics provides readers with information on the development of efficacious nanomedicines as potential theranostic agents for diabetes. The book discusses the application of various novel nanomaterials and nanocomposites for targeted delivery of insulin, glucose sensing, including nano-tattoos as glucose monitors, biosynthesized nanoparticles for diabetes treatment, and pre-clinical and clinical assays to evaluate the efficacy of nanomedicines for diabetes treatment. This is an important references source for materials scientists, pharmaceutical scientists and biomedical engineers who want to increase their understanding of how nanotechnology is being used to improve diabetes treatment. Diabetes has emerged as one of the most common diseases associated with lifestyle choices in the modern world, with significant mortality rates. Conventional treatment methods mainly involve insulin-based therapies. However, insulin therapy possesses several limitations such as weight gain and hypoglycemia. Thus, advanced research in nanomedicine is targeting the development of new and improved diagnostics and treatment methods for diabetes.

Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.

Multi-Objective Combinatorial Optimization Problems and Solution Methods discusses the results of a recent multi-objective combinatorial optimization achievement that considered metaheuristic, mathematical programming, heuristic, hyper heuristic and hybrid approaches. In other words, the book presents various multi-objective combinatorial optimization issues that may benefit from different methods in theory and practice. Combinatorial optimization problems appear in a wide range of applications in operations research, engineering, biological sciences and computer science, hence many optimization approaches have been developed that link the discrete universe to the continuous universe through geometric, analytic and algebraic techniques. This book covers this important topic as computational optimization has become increasingly popular as design optimization and its applications in engineering and industry have become ever more important due to more stringent design requirements in modern engineering practice.

Hybrid Nanomaterials for Drug Delivery covers a broad range of hybrid nanomaterials and nanocomposites used in drug delivery systems. The book reviews a variety of hybrid nanomaterials and structures, including polymer-lipid, chitosan-based, protein-inorganic, quantum dot hybrids, and more. The strengths, limitations and regulatory aspects of hybrid drug delivery systems are also discussed, allowing readers to make informed decisions when choosing to utilize hybrid nanomaterials. Users will find this to be an exciting and comprehensive look into this emerging area. It will be of particular interest to academics and researchers working in materials science, engineering, biomedical engineering, nanotechnology and pharmaceutical science. Multi nanocarrier-based hybrid systems are an emerging concept in the field of drug delivery that allow researchers to avoid some of the challenges faced when administering drugs, such as low bioavailability, development of drug resistance, toxicities, premature drug release, and therapeutic efficacy.

Titanium Alloys for Biomedical Development and Applications: Design, Microstructure, Properties and Application systematically introduces basic theories and progress in the research of biomedical ss-Ti alloys achieved by researchers from different fields. It focuses on a high-strength and low elastic modulus biomedical ss-Ti alloy (TLM), etc. designed by the authors. The alloy design methods, microstructural characteristics, mechanical properties, surface treatment methods and biocompatibility of the TLM alloy are discussed in detail, along with a concise description of the medical devices made from this alloy and the application examples. This book will appeal to researchers as well as students from different disciplines, including materials science, biology, medicine and engineering fields.

Biomedical Product and Materials Evaluation: Standards and Ethics provides a much-needed overview of the procedures, issues, standards and ethical issues in the early development of biomedical products. The book covers a range of key biomedical products, from 3D printed organs and blood derived products, to stem calls and decellularized tissue products. Each chapter reviews a single product type, associated materials, biomedical applications, proven development strategies, and potential challenges. The core focus of the book is on the standardization and ethical aspects of biomedical product development, with these elements addressed and discussed in chapters dedicated to product evaluation. This is a useful reference for academics, researchers and industry professionals in R&D groups with an interest in biomaterial research and production, as well as those working in the fields of biomedical engineering, biotechnology and toxicology.

As technology continues to develop, the healthcare industry must adapt and implement new technologies and services. Recent advancements, opportunities, and challenges for bio-medical image processing and authentication in telemedicine must be considered to ensure patients receive the best possible care. Advancements in Bio-Medical Image Processing and Authentication in Telemedicine introduces recent advancements, opportunities, and challenges for bio-medical image processing and authentication in telemedicine and discusses the design of high-accuracy decision support systems. Covering key topics such as artificial intelligence, medical imaging, telemedicine, and technology, this premier reference source is ideal for medical professionals, nurses, policymakers, researchers, scholars, academicians, practitioners, instructors, and students.

Applied Biomedical Engineering Using Artificial Intelligence and Cognitive Models focuses on the relationship between three different multidisciplinary branches of engineering: Biomedical Engineering, Cognitive Science and Computer Science through Artificial Intelligence models. These models will be used to study how the nervous system and musculoskeletal system obey movement orders from the brain, as well as the mental processes of the information during cognition when injuries and neurologic diseases are present in the human body. The interaction between these three areas are studied in this book with the objective of obtaining AI models on injuries and neurologic diseases of the human body, studying diseases of the brain, spine and the nerves that connect them with the musculoskeletal system. There are more than 600 diseases of the nervous system, including brain tumors, epilepsy, Parkinson's disease, stroke, and many others. These diseases affect the human cognitive system that sends orders from the central nervous system (CNS) through the peripheral nervous systems (PNS) to do tasks using the musculoskeletal system. These actions can be detected by many Bioinstruments (Biomedical Instruments) and cognitive device data, allowing us to apply AI using Machine Learning-Deep Learning-Cognitive Computing models through algorithms to analyze, detect, classify, and forecast the process of various illnesses, diseases, and injuries of the human body. Applied Biomedical Engineering Using Artificial Intelligence and Cognitive Models provides readers with the study of injuries, illness, and neurological diseases of the human body through Artificial Intelligence using Machine Learning (ML), Deep Learning (DL) and Cognitive Computing (CC) models based on algorithms developed with MATLAB (R) and IBM Watson (R).

Wearable Telemedicine Technology for the Healthcare Industry: Product Design and Development focuses on recent advances and benefits of wearable telemedicine techniques for remote health monitoring and prevention of chronic conditions, providing real time feedback and help with rehabilitation and biomedical applications. Readers will learn about various techniques used by software engineers, computer scientists and biomedical engineers to apply intelligent systems, artificial intelligence, machine learning, virtual reality and augmented reality to gather, transmit, analyze and deliver real-time clinical and biological data to clinicians, patients and researchers. Wearable telemedicine technology is currently establishing its place with large-scale impact in many healthcare sectors because information about patient health conditions can be gathered anytime and anywhere outside of traditional clinical settings, hence saving time, money and even lives.

Current Research in Neuroadaptive Technology provides readers with insight into the state-of-the-art field of neuroadaptive technology. The book covers the breadth and depth of current research in this field, covering a range of application domains in sufficient technical detail. The multidisciplinary character of this field means that the publication of key research is often fragmented across specialist journals. Here, the editors have consolidated current research, carefully selecting key topics that are clustered around the concept of neuroadaptive technology. In summary, the book meets the needs of readers by consolidating multidisciplinary research around a nascent technological concept. The topic of neuroadaptive technology is novel and contemporary and editors Dr. Stephen H. Fairclough and Dr. Thorsten O. Zander have captured issues related to this emerging technology at the point of inception. It is a key reference for biomedical engineers and researchers in neural engineering, biomedical engineering, computer science, and mathematics.

Photoplethysmography: Technology, Signal Analysis, and Applications is the first comprehensive volume on the theory, principles, and technology (sensors and electronics) of photoplethysmography (PPG). It provides a detailed description of the current state-of-the-art technologies/optical components enabling the extreme miniaturization of such sensors, as well as comprehensive coverage of PPG signal analysis techniques including machine learning and artificial intelligence. The book also outlines the huge range of PPG applications in healthcare, with a strong focus on the contribution of PPG in wearable sensors and PPG for cardiovascular assessment.