The third edition of this popular problem-solving guide for this widely-used method includes eleven completely new examples and
several updated ones, adding up to 100 contributions about pitfalls and errors in HPLC. Each example is presented on a double page with the
text on the left-hand and a fi gure on the right-hand side, true to the motto 'a picture says more than a thousand words'. In addition, the
author presents essential fundamentals as well as helpful strategies, such as equipment tests or quality assurance processes.
New in this edition
* Variability of the standard deviation
* Infl uence of the acid type and concentration in the eluent
* Water as an unintentional additive in the mobile phase
* Inadequate purity of mobile phase water
* Incomplete degassing
* Inadequate stabilization of the extraction solvent
* Tailing of phosphate compounds in the presence of steel
* Different detection properties of diastereomers
* Detector overload in ELSD
* System suitability test
* From repeatability to reproducibility
A must-have resource for all users - showing how to use HPLC efficiently and obtain reliable results.

Exam Board: OCR Level: A level Subject: Science / Chemistry First teaching: September 2015 First exams: June 2017 An ActiveBook is included with every Student Book, giving your students easy online access to the content in the Student Book. They can make it their own with notes, highlights and links to their wider reading. Perfect for supporting work and revision activities. Student Book 1 supports a standalone AS course and provides the first year of a two-year A level course; Student Books 1 and 2 together support the full A level course. A cumulative approach to learning constantly builds on what has previously been taught. The chapter openers highlight prior learning requirements and link to future learning. The required maths skills are highlighted at the start of each chapter providing opportunities for students to check understanding and remedy gaps. Bigger spreads require students to read real-life material that's relevant to the course and use knowledge in new contexts. Accompanying questions require students to analyse how scientists write, think critically and consider issues. Preparing for your exams sections highlight the key differences between preparing for an AS and full A level exam. Practice question spreads provide opportunities for students to regularly check their understanding using questions written in the style of the new exams from day one.

Basic Laboratory Methods for Biotechnology, Third Edition is a versatile textbook that provides students with a solid foundation to pursue employment in the biotech industry and can later serve as a practical reference to ensure success at each stage in their career. The authors focus on basic principles and methods while skillfully including recent innovations and industry trends throughout. Fundamental laboratory skills are emphasized, and boxed content provides step by step laboratory method instructions for ease of reference at any point in the students' progress. Worked through examples and practice problems and solutions assist student comprehension. Coverage includes safety practices and instructions on using common laboratory instruments. Key Features: Provides a valuable reference for laboratory professionals at all stages of their careers. Focuses on basic principles and methods to provide students with the knowledge needed to begin a career in the Biotechnology industry. Describes fundamental laboratory skills. Includes laboratory scenario-based questions that require students to write or discuss their answers to ensure they have mastered the chapter content. Updates reflect recent innovations and regulatory requirements to ensure students stay up to date. Tables, a detailed glossary, practice problems and solutions, case studies and anecdotes provide students with the tools needed to master the content. To succeed in the lab, it is crucial to be comfortable with the math calculations that are part of everyday work. This accessible introduction to common laboratory techniques focuses on the basics, helping even readers with good math skills to practice the most frequently encountered types of problems. Basic Laboratory Calculations for Biotechnology, Second Edition discusses very common laboratory problems, all applied to real situations. It explores multiple strategies for solving problems for a better understanding of the underlying math. Primarily organized around laboratory applications, the book begins with more general topics and moves into more specific biotechnology laboratory techniques at the end. This book features hundreds of practice problems, all with solutions and many with boxed, complete explanations; plus hundreds of "story problems" relating to real situations in the lab. Additional features include: Discusses common laboratory problems with all material applied to real situations Presents multiple strategies for solving problems help students to better understand the underlying math Provides hundreds of practice problems and their solutions Enables students to complete the material in a self-paced course structure with little teacher assistance Includes hundreds of "story problems"that relate to real situations encountered in the laboratory

Written by an experienced university teacher, this textbook is based on the author's lectures, and is designed to answer students' questions rather than delving into obscure details. The well-balanced approach gives precedence to a visual, intuitive understanding, with only as much math as is necessary. The author covers the topic of symmetry in crystals from basic elements to physical properties, backed by numerous clear-cut illustrations and easy-to-read crystallographic tables.
The result is a compact and self-contained treatment suitable for crystallography courses in physics, chemistry, materials science and biology - irrespective of the academic background.

High-level commentary on various facets of the pharmaceutical industry from a key leader in the field This book clearly explains the value that the pharmaceutical industry offers to society which is often underreported against the more negative topic of high drug prices. It also offers an overview for drug discovery and development professionals, highlighting the challenges that such drug hunters should be aware of when developing new drugs. Case studies to illustrate topics like hepatitis C, mRNA vaccines, insulin, and price controls are included to aid in seamless reader comprehension. Written by John LaMattina, former president of Pfizer Global Research and Development and well-known speaker and writer for the pharma industry, sample topics covered and questions explored within the work include: Fiscal consequences of curing hepatitis C mRNA vaccines and the race for a cure Why the government does not deserve a piece of Biopharma's profits Paying for drugs whose ultimate value is unknown The impact of reduced revenues on R&D This book is a must-read for biopharmaceutical professionals and executives who wish to gain high-level insight into key challenges that must be first understood, then overcome, within the pharmaceutical industry.

This concise, easy-to-read book outlines the basic principles needed to understand the chemical mechanisms of explosion. Written for students with no previous knowledge of explosives but some understanding of chemical reactions in mind, it takes the reader through the history of explosives and introduces the concepts of high explosives, propellants and pyrotechnics. Covering combustion, deflagration, and detonation; ignition, initiation, and thermal decomposition; thermochemistry, thermodynamics and kinetics, the text includes detailed formulations and reactions presented with thermochemical calculations to aid understanding. This edition includes environmental legislation and its impact on explosives, together with a section on safety hazard tests. It also contains the latest developments in synthesis and manufacturing of explosives. Covering all aspects of the properties of explosives, The Chemistry of Explosives is a unique text which introduces difficult subjects in a readable manner. Ideal for A-level students and new graduates with no previous knowledge of explosive materials, it will also be useful to anyone needing succinct information on the subject, such as the more experienced chemist in the explosives sector.

Although a large number of books are available in the fields of solvent extraction and ion exchangers (extraction by chelation or solvation), this book is the first of its kind in the field of liquid ion exchangers (extraction by ion pair formation) which is an upcoming field in solvent extraction chemistry. There are a number of monographs dealing with various aspects of solvent extraction. However, the present title deals in depth with analytical chemistry liquid ion exchangers. This monograph will be very useful to analytical chemists, environmental scientists, chemical processing and material scientists, research workers in solvent extraction as well as postgraduate students majoring in analytical chemistry.This monograph comprises of several chapters. The introduction deals with elementary ideas about liquid ion exchangers and their comparisons with the solid ion exchange resins. The chapter on solvent extraction covers the general classification of mechanisms of extraction and consideration of the extraction equilibria. There are two chapters pertaining to important characteristics and principles of extraction by both liquid anion as well as liquid cation exchangers. The rest of the chapters deal with the separation of elements with liquid ion exchangers, reverse phase partition chromatography and usage of solvent extraction in separation of metals for industrial purposes.

Project managers in drug development are the driving force behind the coordination of efforts. This book provides a practical reference for project managers in the pharmaceutical and biotech drug development industry, with the goal of assisting in creating an efficient and effective team structure and environment. The text details the role of project managers at each stage of drug development, the key interfaces that the PM will need to work closely with, and essential tools of the trade including frequently used techniques and methodologies. This book is useful for both entry-level and advanced-level PMs, as well as non-project managers from other functions. Features Includes authors' recent experience with improved tactics and technologies/software at various stages of drug development. Provides the most up-to-date and best practices, techniques, and methodologies in project management. Details the role of the PM at each stage of drug development, including working with the key interfaces throughout the process. Diverse audience including nonproject managers in clinical development, clinical operations, regulatory affairs, medical affairs, clinical pharmacology, and biostatistics. Provides templates and timelines for critical paths from development to commercialization and has potential as a textbook on relevant courses.

This new and improved CGP Complete Revision & Practice book for Year 2 of AQA A-Level Chemistry is perfect for reference throughout the year, and preparing for the final exams! It has straightforward study notes, helpful examples and full-colour diagrams. We've included more challenging exam practice than ever before with plenty of practice questions and exam-style questions (with detailed answers) for every topic - plus a section of mixed (synoptic) practice testing different parts of the course. To round things off there are sections of in-depth advice on Practical Skills and how to pick up top marks in the exams. There's even a free Online Edition of the whole book - just use the code printed inside the book to access it on your PC, Mac or tablet. For even more practice don't miss CGP's Year 2 of A-Level Chemistry Exam Practice Workbook (9781782949121).

This first systematic scientific reference in the area of micro- and nanostructured biopolymer systems discusses in two volumes the morphology, structure, dynamics, properties and applications of all important biopolymers, as well as their blends, composites, interpenetrating networks and gels.
Selected leading researchers from industry, academia, government and private research institutions around the globe comprehensively review recent accomplishments in the field. They examine the current state of the art, new challenges, and opportunities, discussing all
the synthetic routes to the generation of both micro- and nano-morphologies, as well as the synthesis, characterization and application of porous biopolymers.
An outstanding resource for anyone involved in the fi eld of eco-friendly biomaterials for advanced technologies.

Target exam success with My Revision Notes. Our updated approach to revision will help you learn, practise and apply your skills and understanding. Coverage of key content is combined with practical study tips and effective revision strategies to create a guide you can rely on to build both knowledge and confidence. My Revision Notes: WJEC/Eduqas A-level Chemistry will help you: * Develop your subject knowledge by making links between topics for more in-depth exam answers * Practise and apply your skills and knowledge with exam-style questions and frequent 'Now Test Yourself' questions with answer guidance online * Improve maths skills with helpful reminders and tips accompanied by worked examples * Avoid common mistakes and enhance your exam answers with 'Examiner tips' * Build quick recall with bullet-pointed summaries at the end of each chapter * Understand key terms you will need for the exam with user-friendly definitions and a glossary * Plan and manage your revision with our topic-by-topic planner and exam breakdown introduction

Welcome to a tour of some of the recent advances in chemistry, taking in the cosmetic factory, the pharmacy, the grooming salon, the diet clinic, the power plant, the domestic cleaning company, and the art gallery along the way. Award-winning popular science writer John Emsley is our guide as he addresses questions of grooming, health, food, and sex. The trip is for all those of us wanting to know more about the impact of chemical products on our everyday lives.
Each chapter begins with a fictional news item from the future speculating on the possible benefits that might develop from further approaches to research, and each chapter ends by addressing an issue of concern related to the topics discussed. These include whether homeopathic medicines really work, date rape drugs, how the toxic chemical acrylamide got into our food, and whether great artists were affected by the pigments they used.
With his informal style, linking well-founded chemicals knowledge to fun situations, the author presents the information in a way such that the layperson can easily understand the arguments, weighing up the risks and benefits for each product concerned.
Includes a glossary containing all the technical terms used for non-specialists.

Please note this title is suitable for any student studying: Exam Board: OCR Level: A Level Year 2 Subject: Chemistry First teaching: September 2015 First exams: June 2017 Written by curriculum and specification experts in partnership with OCR, this Student Book supports and extends students through the new course while delivering the breadth, depth, and skills needed to succeed in the new A Level and beyond. It develops true subject knowledge while also developing essential exam skills. Covers the second year worth of content required for the new OCR Chemistry A A Level specification.

The use of silver as an antibacterial agent has been known for thousands of years. This effect can be amplified by simply reducing the size of silver particles to the nanoscale, with an added advantage of reduction in cost and toxicity. Application of silver nanoparticles to textiles can bring considerable advantages, especially for materials that cannot be washed daily or medical support materials. This book describes a novel synthesis method that the author calls "in situ," in which these nanoparticles are obtained directly on materials. The method is simple and easy to apply and can also be considered green because the reducing agent involved is ascorbic acid, commonly known as vitamin C. It neither requires special modifications in the industrial equipment nor special pressure or temperature conditions. It can be used to grow other metals or metal oxides on a material. The book showcases studies carried out on silver nanoparticles by the author over several years, not only in terms of the synthesis but also the morphological characterization of the substrate to which they were applied. It exhibits SEM images displaying the homogeneity of the silver coating, highlighting that sometimes the simplest way is the best way.

This handy reference is the first comprehensive book covering both fundamentals and recent developments in the field with an emphasis on nanotechnology.

Written by a highly regarded author in the field, the book details state-of-the-art preparation, characterization and applications of thin films of organic molecules and biomaterials fabricated by wet processes and also highlights applications in nanotechnology

The categories of films covered include monomolecular films (monolayers) both on a water surface and on a solid plate, Langmuir-Blodgett films (transferred multilayer films on a solid plate from a water surface), layer-by-layer films (adsorbed multilayer films on a solid support), and spontaneously assembled films in solution.

Offering practical, real-life applications, coverage of basic concepts, and an engaging visual style, this proven book offers a writing style, approach, and selection of topics ideal for non-chemistry science majors. This edition offers an updated, dynamic art program (online, on CD, and in the text), new content to keep you current with developments in the organic chemistry field, and a revised lab manual.

Introduces an innovative and outstanding tool for the easy synthesis of complex chiral structures in a single step Covering all of the literature since the beginning of 2006, this must-have book for chemists collects the major progress in the field of enantioselective one-, two-, and multicomponent domino reactions promoted by chiral metal catalysts. It clearly illustrates how enantioselective metal-catalyzed processes constitute outstanding tools for the development of a wide variety of fascinating one-pot asymmetric domino reactions, thereby allowing many complex products to be easily generated from simple materials in one step. The book also strictly follows the definition of domino reactions by Tietze as single-, two-, as well as multicomponent transformations. Asymmetric Metal Catalysis in Enantioselective Domino Reactions is divided into twelve chapters, dealing with enantioselective copper-, palladium-, rhodium-, scandium-, silver-, nickel-, gold-, magnesium-, cobalt-, zinc-, yttrium and ytterbium-, and other metal-catalyzed domino reactions. Most of the chapters are divided into two parts dealing successively with one- and two-component domino reactions, and three-component processes. Each part is subdivided according to the nature of domino reactions. Each chapter of the book includes selected applications of synthetic methodologies to prepare natural and biologically active products. -Presents the novel combination of asymmetric metal catalysis with the concept of fascinating domino reactions, which allows high molecular complexity with a remarkable level of enantioselectivity -Showcases an incredible tool synthesizing complex and diverse chiral structures in a single reaction step -Includes applications in total synthesis of natural products and biologically active compounds -Written by a renowned international specialist in the field -Stimulates the design of novel asymmetric domino reactions and their use in the synthesis of natural products, pharmaceuticals, agrochemicals, and materials Asymmetric Metal Catalysis in Enantioselective Domino Reactions will be of high interest to synthetic, organic, medicinal, and catalytic chemists in academia and R&D departments.

Learn the skills you need to succeed in your chemistry course with CHEMISTRY, Tenth Edition. This trusted text has helped generations of students learn to "think like chemists" and develop problem-solving skills needed to master even the most challenging problems. Clear explanations and interactive examples help you build confidence for the exams, so that you can study to understand rather than simply memorize. Combined with the online resources and instant feedback in OWLv2, you'll be on your way to developing a deeper understanding of chemistry concepts and solving complex problems in all aspects of your life.

This profusely illustrated book is intended to provide a comprehensive exposition of different aspects of organic and name reactions in detail including rearrangements such as mechanisms, stereochemistry and their applications with illustrations, figures, schemes and reaction series in such a way that it should not be difficult for the reader to evaluate typical reaction condition, workup procedure etc. Each chapter is accompanied with conceptual, theoretical and numerical problems along with references. The reaction series of schemes of organic and name reactions provide the way for rapid revision of the topics. All this should be of great help to research scholars, postgraduate students and teachers.

The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and E. Khosravi, Volume 3 of the 3-volume work focusses on polymer synthesis. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry. View the set here - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527334246.html Other available volumes: Volume 1: Catalyst Development and Mechanism, Editors: R. H. Grubbs and A. G. Wenzel - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 2: Applications in Organic Synthesis, Editors: R. H. Grubbs and D. J. O'Leary - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339493.html

Exam Board: CCEA Level: A-level Subject: Chemistry First Teaching: September 2016 First Exam: June 2018 Reinforce students' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher grades Written by examiners and teachers, Student Guides: * Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification * Consolidate understanding with exam tips and knowledge check questions * Provide opportunities to improve exam technique with sample graded answers to exam-style questions * Develop independent learning and research skills * Provide the content for generating individual revision notes

Eine pragnante, gut strukturierte Einfuhrung in die Anwendungen von DFT-Berechnungen In der neu uberarbeiteten zweiten Auflage von Density Functional Theory: A Practical Introduction liefern die Autoren eine pragnante und leicht verstandliche Einfuhrung in die wichtigsten Konzepte und praktischen Anwendungen der Dichtefunktionaltheorie (DFT), wobei der Schwerpunkt auf die DFT der ebenen Wellen gelegt wird. Die Autoren, die uber jahrzehntelange Erfahrung auf diesem Gebiet verfugen, bieten Studierenden mit unterschiedlichen Vorkenntnissen ein ausgewogenes Mass an Verstandlichkeit und Klarheit und haben auf diese Weise ein insgesamt sehr gut zu verstehendes Fachbuch verfasst. * In dieser neuen Auflage werden die Genauigkeit von DFT-Berechnungen und die Wahl der Funktionale detailliert eroertert * Das Werk bietet einen UEberblick uber ein breites Spektrum an verfugbaren DFT-Codes * Mit zusatzlichen Beispielen zur Nutzung von DFT fur Berechnungen von Materialien mit hohem Durchsatz * Starkere Hervorhebung der Berechnung von Phasendiagrammen und offener Ensemble-Methoden, die in der Elektrochemie umfassend genutzt werden. * In dieser erweiterten Auflage werden auch Berechnungen abgedeckt, die uber die Standard-DFT hinausgehen, z. B. DFT mit Dispersionskorrektur, DFT+U und zeitabhangige DFT

Providing the reader with a solid understanding of the fundamentals as well as an awareness of recent advances in properties and applications of cellular and porous materials, this handbook and ready reference covers all important analytical and numerical methods for characterizing and predicting thermal properties. In so doing it directly addresses the special characteristics of foam-like and hole-riddled materials, combining theoretical and experimental aspects for characterization purposes.

The second, completely revised and enlarged edition of what has become the standard reference work in this fascinating field brings together the latest developments, supplemented by numerous practical tips, providing those working in both research and industry with an indispensable source of information. New contributions have been added, to reflect the fact that industrial processes are already established, and ionic liquids are now commercially available.
A must for everyone working in the field.