Simulation Methods for Reliability and Availability of Complex Systems discusses the use of computer simulation-based techniques and algorithms to determine reliability and availability (R and A) levels in complex systems. The book: shares theoretical or applied models and decision support systems that make use of simulation to estimate and to improve system R and A levels, forecasts emerging technologies and trends in the use of computer simulation for R and A and proposes hybrid approaches to the development of efficient methodologies designed to solve R and A-related problems in real-life systems.

Dealing with practical issues, Simulation Methods for Reliability and Availability of Complex Systems is designed to support managers and system engineers in the improvement of R and A, as well as providing a thorough exploration of the techniques and algorithms available for researchers, and for advanced undergraduate and postgraduate students.

This book aims to provide a description of these new Artificial Intelligence technologies and approaches to the modeling and simulation of complex systems, as well as an overview of the latest scientific efforts in this field such as the platforms and/or the software tools for smart modeling and simulating complex systems. These tasks are difficult to accomplish using traditional computational approaches due to the complex relationships of components and distributed features of resources, as well as the dynamic work environments. In order to effectively model the complex systems, intelligent technologies such as multi-agent systems and smart grids are employed to model and simulate the complex systems in the areas of ecosystem, social and economic organization, web-based grid service, transportation systems, power systems and evacuation systems.

This major reference work represents the first attempt to confront, on a world-wide basis, the way computer associations face up to their own responsibilities in an age increasingly dominated by information and communication technology. The book deals with the codes of ethics and conduct, and related issues. It is the first book to deal with homogenous codes namely codes of national computer societies. Some thirty codes are compared and analysed in depth. To put these into perspective, there are discussion papers covering the methodological, philosophical and organisational issues.

The operation of understanding is the fundamental methodical procedure of hermeneutics and is usually seen as contradiction to scientific explanation by the usage of mathematical models. Yet understanding is the basic way in which humans organize their everyday practice, namely by understanding other people and social situations. In this book the authors demonstrate how an integration of hermeneutical understanding and scientific explanation can be done via the construction of suited geometrical models with neural networks of processes of understanding. In this sense the authors develop some kind of mathematical hermeneutics. Connecting links for the integration of the two methodical poles are the developments of particular models of Artificial Intelligence (AI), which are able to perform certain tasks of understanding.

The book presents select proceedings of Global meet on 'Computational Modelling and Simulation, Recent Innovations, Challenges and Perspectives, 2020. This book covers leading-edge technologies from different domains such as computation in optimization and control, multiscale and multiphysics modeling and computation analysis, environmental modeling, modeling approaches to enterprise systems and services, finite element analysis, dependability and security, high-performance computation/cloud computing applications, computational biology and chemistry and computational mechanics. The primary goal of this book is to strengthen pre-eminence in computational modeling and simulation by catalyzing the transformative use of innovative developments in a wide range of disciplines to achieve lasting societal impact. The book discusses on how to perform simulation of large complex dynamic systems in an efficient manner using advanced computational analysis. The inter-disciplinary nature of the book would be a valuable reference for academicians and research scientists, industrialists interested in modelling and simulation driven by computational technology.

The planned construction of traffic routes through the European Alps represents a challenge for science and technology. In the past decades, Austria has gained a leading position in the field of tunnelling. This has been verified by many successful projects all over the world, which have been realised with the well-known "New Austrian Tunnelling Method". However, further development and economic success of modern tunnelling methods, which are still partly based on empirical assumptions, can only be assured if their scientific basis is improved. The book discusses the application of numerical simulation methods to assist tunnel engineers. Numerical simulation tools for the estimation of the required tunnel support and the required construction measures are described in this book. By using them, it is possible to study the impact on construction and environment during the planning stage and during construction. This will result in an improvement of the safety and economy of tunnels.

This fully updated book explores all-new and revised protocols involving the use of in silico models, particularly with regard to pharmaceuticals. Divided into five sections, the volume covers the modeling of pharmaceuticals in the body, toxicity data for modeling purposes, in silico models for multiple endpoints, a number of platforms for evaluating pharmaceuticals, as well as an exploration of challenges, both scientific and sociological. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice necessary for successful results. Authoritative and comprehensive, In Silico Methods for Predicting Drug Toxicity, Second Edition aims to guide the reader through the correct procedures needed to harness in silico models, a field which now touches a wide variety of research specialties.

This book provides a comprehensive overview of potential opportunities and the business value position related to implementing physics-based real-time simulation to production. The objective of real-time simulation is to provide value for all three dimensions of sustainability: economic, social, and environmental. By reviewing actual industrial cases and presenting relevant academic research, the book examines the topic from four interrelated viewpoints: the industrial need for sustainable production, the development of game-like virtual environments, capturing customer value and enhancing the user experience, and finally, establishing business value. It offers a framework that will enable a rethink and shift in mindset to appreciate how real-time simulation can change the way products are manufactured and services are produced. This book will appeal to researchers and scholars in areas as diverse as strategic management, manufacturing and operations management, marketing, industrial economics, and product lifecycle management.

Computer simulation, a powerful technological tool and research-proven pedagogical technique, holds great potential to enhance and transform teaching and learning in education and is therefore a viable tool to engage students in deep learning and higher-order thinking. With the advancement of simulation technology (e.g., virtual reality, artificial intelligence, machine learning) and the expanded disciplines where computer simulation is being used (e.g., data science, cyber security), computer simulation is playing an increasingly significant role in leading the digital transformation in K-12 schools and higher education institutions, as well as training and professional development in corporations, government, and the military. Teaching, Learning, and Leading With Computer Simulations is an important compilation of research that examines the recent advancement of simulation technology and explores innovative ways to utilize advanced simulation programs for the enhancement of teaching and learning outcomes. Highlighting a range of topics such as pedagogy, immersive learning, and social sciences, this book is essential for educators, higher education institutions, deans, curriculum designers, school administrators, principals, IT specialists, academicians, researchers, policymakers, and students.

This work contains an up-to-date coverage of the last 20 years' advances in Bayesian inference in econometrics, with an emphasis on dynamic models. It shows how to treat Bayesian inference in non linear models, by integrating the useful developments of numerical integration techniques based on simulations (such as Markov Chain Monte Carlo methods), and the long available analytical results of Bayesian inference for linear regression models. It thus covers a broad range of rather recent models for economic time series, such as non linear models, autoregressive conditional heteroskedastic regressions, and cointegrated vector autoregressive models. It contains also an extensive chapter on unit root inference from the Bayesian viewpoint. Several examples illustrate the methods. This book is intended for econometrics and statistics postgraduates, professors and researchers in economics departments, business schools, statistics departments, or any research centre in the same fields, especially econometricians.

The competitiveness of firms, regions and countries greatly depends on the generation, dissemination and application of new knowledge. Modern innovation research is challenged by the need to incorporate knowledge generation and dissemination processes into the analysis so as to disentangle the complexity of these dynamic processes. With innovation, however, strong uncertainty, nonlinearities and actor heterogeneity become central factors that are at odds with traditional modeling techniques anchored in equilibrium and homogeneity. This text introduces SKIN (Simulation Knowledge Dynamics in Innovation Networks), an agent-based simulation model that primarily focuses on joint knowledge creation and exchange of knowledge in innovation co-operations and networks. In this context, knowledge is explicitly modeled and not approximated by, for instance, the level of accumulated R&D investment. The SKIN approach supports applications in different domains ranging from sector-based research activities in knowledge-intensive industries to the activities of international research consortia engaged in basic and applied research. Following a general description of the SKIN model, several applications and modifications are presented. Each chapter introduces in detail the structure of the model, the relevant methodological considerations and the analysis of simulation results, while options for empirically validating the models' structure and outcomes are also discussed. The book considers the scope of further applications and outlines prospects for the development of joint modeling strategies.

This book focuses on the mathematical potential and computational efficiency of the Boundary Element Method (BEM) for modeling seismic wave propagation in either continuous or discrete inhomogeneous elastic/viscoelastic, isotropic/anisotropic media containing multiple cavities, cracks, inclusions and surface topography. BEM models may take into account the entire seismic wave path from the seismic source through the geological deposits all the way up to the local site under consideration. The general presentation of the theoretical basis of elastodynamics for inhomogeneous and heterogeneous continua in the first part is followed by the analytical derivation of fundamental solutions and Green's functions for the governing field equations by the usage of Fourier and Radon transforms. The numerical implementation of the BEM is for antiplane in the second part as well as for plane strain boundary value problems in the third part. Verification studies and parametric analysis appear throughout the book, as do both recent references and seminal ones from the past. Since the background of the authors is in solid mechanics and mathematical physics, the presented BEM formulations are valid for many areas such as civil engineering, geophysics, material science and all others concerning elastic wave propagation through inhomogeneous and heterogeneous media. The material presented in this book is suitable for self-study. The book is written at a level suitable for advanced undergraduates or beginning graduate students in solid mechanics, computational mechanics and fracture mechanics.

Over the past thirty years, with improvements in optics, electronics, and computer technology, great strides have been made in the quantitative analysis of the visual system. A number of books on eye movement research have been written that have dealt with specific aspects of either eye movement control. However, none of these books provide a comprehensive overview of multiple aspects of the visual system. Moreover, few of these books contain modeling and detailed quantitative analyses of the visual system. Further, since the major books are almost ten years old, there is a need for an update to include the most recent research findings. It is with these considerations in mind that we have carefully compiled this updated, comprehensive, and quantitative model-based edited book on various components of the visual system. Some of the best vision scientists in the world in their respective fields have contributed to chapters in this book. They have expertise in a wide variety of fields, including bioengineering, basic and clinical visual science, medicine, neurophysiology, optometry, and psychology. Their combined efforts have resulted in a high quality book that covers modeling and quantitative analysis of optical, neurosensory, oculomotor, perceptual and clinical systems. It includes only those techniques and models that have such fundamentally strong physiological, control system, and perceptual bases that they will serve as foundations for models and analysis techniques in the future. The book is aimed first towards seniors and beginning graduate students in biomedical engineering, neurophysiology, optometry, and psychology, who will gain a broad understanding of quantitative analysisof the visual system. In addition, it has sufficient depth in each area to be useful as an updated reference and tutorial for graduate and post-doctoral students, as well as general vision scientists.

"Social Simulation for a Digital Society" provides a cross-section of state-of-the-art research in social simulation and computational social science. With the availability of big data and faster computing power, the social sciences are undergoing a tremendous transformation. Research in computational social sciences has received considerable attention in the last few years, with advances in a wide range of methodologies and applications. Areas of application of computational methods range from the study of opinion and information dynamics in social networks, the formal modeling of resource use, the study of social conflict and cooperation to the development of cognitive models for social simulation and many more. This volume is based on the Social Simulation Conference of 2017 in Dublin and includes applications from across the social sciences, providing the reader with a demonstration of the highly versatile research in social simulation, with a particular focus on public policy relevance in a digital society. Chapters in the book include contributions to the methodology of simulation-based research, theoretical and philosophical considerations, as well as applied work. This book will appeal to students and researchers in the field.

The papers in this volume comprise the refereed proceedings of the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA2008), in Beijing, China, 2008. The conference on the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA 2008) is cooperatively sponsored and organized by the China Agricultural University (CAU), the National Engineering Research Center for Information Technology in Agriculture (NERCITA), the Chinese Society of Agricultural Engineering (CSAE) , International Federation for Information Processing (IFIP), Beijing Society for Information Technology in Agriculture, China and Beijing Research Center for Agro-products Test and Farmland Inspection, China. The related departments of China's central government bodies like: Ministry of Science and Technology, Ministry of Industry and Information Technology, Ministry of Education and the Beijing Municipal Natural Science Foundation, Beijing Academy of Agricultural and Forestry Sciences, etc. have greatly contributed and supported to this event. The conference is as good platform to bring together scientists and researchers, agronomists and information engineers, extension servers and entrepreneurs from a range of disciplines concerned with impact of Information technology for sustainable agriculture and rural development. The representatives of all the supporting organizations, a group of invited speakers, experts and researchers from more than 15 countries, such as: the Netherlands, Spain, Portugal, Mexico, Germany, Greece, Australia, Estonia, Japan, Korea, India, Iran, Nigeria, Brazil, China, etc.

Weed management Decision Support Systems (DSS) are increasingly important computer-based tools for modern agriculture. Nowadays, extensive agriculture has become highly dependent on external inputs and both economic costs, as well the negative environmental impact of agricultural activities, demands knowledge-based technology for the optimization and protection of non-renewable resources. In this context, weed management strategies should aim to maximize economic profit by preserving and enhancing agricultural systems. Although previous contributions focusing on weed biology and weed management provide valuable insight on many aspects of weed species ecology and practical guides for weed control, no attempts have been made to highlight the forthcoming importance of DSS in weed management. This book is a first attempt to integrate `concepts and practice' providing a novel guide to the state-of-art of DSS and the future prospects which hopefully would be of interest to higher-level students, academics and professionals in related areas.

This book focuses on the problem of responsibility voids: these are cases where responsibility for a morally undesirable outcome cannot be attributed to any of the involved agents. Responsibility voids are thought to occur in collective decision-making and in the context of artificial intelligent systems. In these cases, philosophers worry that there is a shortfall of moral responsibility. In particular, such voids are often assumed to justify a notion of collective responsibility that cannot be reduced to individual responsibility. One of the aims of the book is to study how collective responsibility and joint action relate to individual responsibility and individual actions. The book offers a unifying framework for modelling moral responsibility by drawing from modal logic and game theory. The book investigates the possibility and scope of the problem of responsibility voids. One of its characteristics is its pluralistic perspective on moral responsibility: in contrast to giving a unique and all-encompassing definition of it, the book makes progress by spelling out and modelling several conceptions of moral responsibility. One of the appealing features of the book is that a relatively small range of models is used to investigate a variety of conceptions of moral responsibility. The unifying framework can thus be used to characterize the conditions under which responsibility voids are ruled out.

3D Mesh Processing and Character Animation focusses specifically on topics that are important in three-dimensional modelling, surface design and real-time character animation. It provides an in-depth coverage of data structures and popular methods used in geometry processing, keyframe and inverse kinematics animations and shader based processing of mesh objects. It also introduces two powerful and versatile libraries, OpenMesh and Assimp, and demonstrates their usefulness through implementations of a wide range of algorithms in mesh processing and character animation respectively. This Textbook is written for students at an advanced undergraduate or postgraduate level who are interested in the study and development of graphics algorithms for three-dimensional mesh modeling and analysis, and animations of rigged character models. The key topics covered in the book are mesh data structures for processing adjacency queries, simplification and subdivision algorithms, mesh parameterization methods, 3D mesh morphing, skeletal animation, motion capture data, scene graphs, quaternions, inverse kinematics algorithms, OpenGL-4 tessellation and geometry shaders, geometry processing and terrain rendering.

This book introduces modeling and simulation of linear time invariant systems and demonstrates how these translate to systems engineering, mechatronics engineering, and biomedical engineering. It is organized into nine chapters that follow the lectures used for a one-semester course on this topic, making it appropriate for students as well as researchers. The author discusses state space modeling derived from two modeling techniques and the analysis of the system and usage of modeling in control systems design. It also contains a unique chapter on multidisciplinary energy systems with a special focus on bioengineering systems and expands upon how the bond graph augments research in biomedical and bio-mechatronics systems.

This essential volume explores a variety of tools and protocols of structure-based (homology modeling, molecular docking, molecular dynamics, protein-protein interaction network) and ligand-based (pharmacophore mapping, quantitative structure-activity relationships or QSARs) drug design for ranking and prioritization of candidate molecules in search of effective treatment strategy against coronaviruses. Beginning with an introductory section that discusses coronavirus interactions with humanity and COVID-19 in particular, the book then continues with sections on tools and methodologies, literature reports and case studies, as well as online tools and databases that can be used for computational anti-coronavirus drug research. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of practical detail and implementation advice that ensures high quality results in the lab. Comprehensive and timely, In Silico Modeling of Drugs Against Coronaviruses: Computational Tools and Protocols is an ideal reference for researchers working on the development of novel anti-coronavirus drugs for SARS-CoV-2 and for coronaviruses that will likely appear in the future.

This book is a collection of papers presented at the Forum The Impact of Applications on Mathematics in October 2013. It describes an appropriate framework in which to highlight how real-world problems, over the centuries and today, have influenced and are influencing the development of mathematics and thereby, how mathematics is reshaped, in order to advance mathematics and its application. The contents of this book address productive and successful interaction between industry and mathematicians, as well as the cross-fertilization and collaboration that result when mathematics is involved with the advancement of science and technology."

Aerodynamic design, like many other engineering applications, is increasingly relying on computational power. The growing need for multi-disciplinarity and high fidelity in design optimization for industrial applications requires a huge number of repeated simulations in order to find an optimal design candidate. The main drawback is that each simulation can be computationally expensive - this becomes an even bigger issue when used within parametric studies, automated search or optimization loops, which typically may require thousands of analysis evaluations. The core issue of a design-optimization problem is the search process involved. However, when facing complex problems, the high-dimensionality of the design space and the high-multi-modality of the target functions cannot be tackled with standard techniques. In recent years, global optimization using meta-models has been widely applied to design exploration in order to rapidly investigate the design space and find sub-optimal solutions. Indeed, surrogate and reduced-order models can provide a valuable alternative at a much lower computational cost. In this context, this volume offers advanced surrogate modeling applications and optimization techniques featuring reasonable computational resources. It also discusses basic theory concepts and their application to aerodynamic design cases. It is aimed at researchers and engineers who deal with complex aerodynamic design problems on a daily basis and employ expensive simulations to solve them.

This book explores Autonomic Nervous System (ANS) dynamics as investigated through Electrodermal Activity (EDA) processing. It presents groundbreaking research in the technical field of biomedical engineering, especially biomedical signal processing, as well as clinical fields of psychometrics, affective computing, and psychological assessment. This volume describes some of the most complete, effective, and personalized methodologies for extracting data from a non-stationary, nonlinear EDA signal in order to characterize the affective and emotional state of a human subject. These methodologies are underscored by discussion of real-world applications in mood assessment. The text also examines the physiological bases of emotion recognition through noninvasive monitoring of the autonomic nervous system. This is an ideal book for biomedical engineers, physiologists, neuroscientists, engineers, applied mathmeticians, psychiatric and psychological clinicians, and graduate students in these fields. This book also: Expertly introduces a novel approach for EDA analysis based on convex optimization and sparsity, a topic of rapidly increasing interest Authoritatively presents groundbreaking research achieved using EDA as an exemplary biomarker of ANS dynamics Deftly explores EDA's potential as a source of reliable and effective markers for the assessment of emotional responses in healthy subjects, as well as for the recognition of pathological mood states in bipolar patients

3D rotation analysis is widely encountered in everyday problems thanks to the development of computers. Sensing 3D using cameras and sensors, analyzing and modeling 3D for computer vision and computer graphics, and controlling and simulating robot motion all require 3D rotation computation. This book focuses on the computational analysis of 3D rotation, rather than classical motion analysis. It regards noise as random variables and models their probability distributions. It also pursues statistically optimal computation for maximizing the expected accuracy, as is typical of nonlinear optimization. All concepts are illustrated using computer vision applications as examples. Mathematically, the set of all 3D rotations forms a group denoted by SO(3). Exploiting this group property, we obtain an optimal solution analytical or numerically, depending on the problem. Our numerical scheme, which we call the "Lie algebra method," is based on the Lie group structure of SO(3). This book also proposes computing projects for readers who want to code the theories presented in this book, describing necessary 3D simulation setting as well as providing real GPS 3D measurement data. To help readers not very familiar with abstract mathematics, a brief overview of quaternion algebra, matrix analysis, Lie groups, and Lie algebras is provided as Appendix at the end of the volume.

This manual describes the wide range of electromechanical, electrochemical and electro-optical transducers at the heart of current field-deployable ocean observing instruments. Their modes of operation, precision and accuracy are discussed in detail. Observing platforms ranging from the traditional to the most recently developed are described, as are the challenges of integrating instrument suits to individual platforms. Technical approaches are discussed to address environmental constraints on instrument and platform operation such as power sources, corrosion, biofouling and mechanical abrasion. Particular attention is also given to data generated by the networks of observing platforms that are typically integrated into value-added data visualization products, including numerical simulations or models. Readers will learn about acceptable data formats and representative model products. The last section of the book is devoted to the challenges of planning, deploying and maintaining coastal ocean observing systems. Readers will discover practical applications of ocean observations in diverse fields including natural resource conservation, commerce and recreation, safety and security, and climate change resiliency and adaptation. This volume will appeal to ocean engineers, oceanographers, commercial and recreational ocean data users, observing systems operators, and advanced undergraduate and graduate students in the field of ocean observing.