The papers in this volume comprise the refereed proceedings of the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA2008), in Beijing, China, 2008. The conference on the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA 2008) is cooperatively sponsored and organized by the China Agricultural University (CAU), the National Engineering Research Center for Information Technology in Agriculture (NERCITA), the Chinese Society of Agricultural Engineering (CSAE) , International Federation for Information Processing (IFIP), Beijing Society for Information Technology in Agriculture, China and Beijing Research Center for Agro-products Test and Farmland Inspection, China. The related departments of China's central government bodies like: Ministry of Science and Technology, Ministry of Industry and Information Technology, Ministry of Education and the Beijing Municipal Natural Science Foundation, Beijing Academy of Agricultural and Forestry Sciences, etc. have greatly contributed and supported to this event. The conference is as good platform to bring together scientists and researchers, agronomists and information engineers, extension servers and entrepreneurs from a range of disciplines concerned with impact of Information technology for sustainable agriculture and rural development. The representatives of all the supporting organizations, a group of invited speakers, experts and researchers from more than 15 countries, such as: the Netherlands, Spain, Portugal, Mexico, Germany, Greece, Australia, Estonia, Japan, Korea, India, Iran, Nigeria, Brazil, China, etc.

This fully updated book explores all-new and revised protocols involving the use of in silico models, particularly with regard to pharmaceuticals. Divided into five sections, the volume covers the modeling of pharmaceuticals in the body, toxicity data for modeling purposes, in silico models for multiple endpoints, a number of platforms for evaluating pharmaceuticals, as well as an exploration of challenges, both scientific and sociological. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice necessary for successful results. Authoritative and comprehensive, In Silico Methods for Predicting Drug Toxicity, Second Edition aims to guide the reader through the correct procedures needed to harness in silico models, a field which now touches a wide variety of research specialties.

This book provides a comprehensive overview of potential opportunities and the business value position related to implementing physics-based real-time simulation to production. The objective of real-time simulation is to provide value for all three dimensions of sustainability: economic, social, and environmental. By reviewing actual industrial cases and presenting relevant academic research, the book examines the topic from four interrelated viewpoints: the industrial need for sustainable production, the development of game-like virtual environments, capturing customer value and enhancing the user experience, and finally, establishing business value. It offers a framework that will enable a rethink and shift in mindset to appreciate how real-time simulation can change the way products are manufactured and services are produced. This book will appeal to researchers and scholars in areas as diverse as strategic management, manufacturing and operations management, marketing, industrial economics, and product lifecycle management.

Algorithmic design is not simply the use of computer to design architecture and objects. Algorithms allow designers to overcome the limitations of traditional CAD software and 3D modelers, reaching a level of complexity and control which is beyond the human manual ability. Algorithms-Aided Design presents design methods based on the use of Grasshopper (R), a visual algorithm editor tightly integrated with Rhinoceros (R), the 3D modeling software by McNeel & Associates allowing users to explore accurate freeform shapes. The book provides computational techniques to develop and control complex geometries, covering parametric modeling, digital fabrication techniques, form-finding strategies, environmental analysis and structural optimization. It also features case studies and contributions by researchers and designers from world's most influential universities and leading architecture firms.

This book introduces modeling and simulation of linear time invariant systems and demonstrates how these translate to systems engineering, mechatronics engineering, and biomedical engineering. It is organized into nine chapters that follow the lectures used for a one-semester course on this topic, making it appropriate for students as well as researchers. The author discusses state space modeling derived from two modeling techniques and the analysis of the system and usage of modeling in control systems design. It also contains a unique chapter on multidisciplinary energy systems with a special focus on bioengineering systems and expands upon how the bond graph augments research in biomedical and bio-mechatronics systems.

"Social Simulation for a Digital Society" provides a cross-section of state-of-the-art research in social simulation and computational social science. With the availability of big data and faster computing power, the social sciences are undergoing a tremendous transformation. Research in computational social sciences has received considerable attention in the last few years, with advances in a wide range of methodologies and applications. Areas of application of computational methods range from the study of opinion and information dynamics in social networks, the formal modeling of resource use, the study of social conflict and cooperation to the development of cognitive models for social simulation and many more. This volume is based on the Social Simulation Conference of 2017 in Dublin and includes applications from across the social sciences, providing the reader with a demonstration of the highly versatile research in social simulation, with a particular focus on public policy relevance in a digital society. Chapters in the book include contributions to the methodology of simulation-based research, theoretical and philosophical considerations, as well as applied work. This book will appeal to students and researchers in the field.

Weed management Decision Support Systems (DSS) are increasingly important computer-based tools for modern agriculture. Nowadays, extensive agriculture has become highly dependent on external inputs and both economic costs, as well the negative environmental impact of agricultural activities, demands knowledge-based technology for the optimization and protection of non-renewable resources. In this context, weed management strategies should aim to maximize economic profit by preserving and enhancing agricultural systems. Although previous contributions focusing on weed biology and weed management provide valuable insight on many aspects of weed species ecology and practical guides for weed control, no attempts have been made to highlight the forthcoming importance of DSS in weed management. This book is a first attempt to integrate `concepts and practice' providing a novel guide to the state-of-art of DSS and the future prospects which hopefully would be of interest to higher-level students, academics and professionals in related areas.

This book is a collection of papers presented at the Forum The Impact of Applications on Mathematics in October 2013. It describes an appropriate framework in which to highlight how real-world problems, over the centuries and today, have influenced and are influencing the development of mathematics and thereby, how mathematics is reshaped, in order to advance mathematics and its application. The contents of this book address productive and successful interaction between industry and mathematicians, as well as the cross-fertilization and collaboration that result when mathematics is involved with the advancement of science and technology."

The book presents select proceedings of Global meet on 'Computational Modelling and Simulation, Recent Innovations, Challenges and Perspectives, 2020. This book covers leading-edge technologies from different domains such as computation in optimization and control, multiscale and multiphysics modeling and computation analysis, environmental modeling, modeling approaches to enterprise systems and services, finite element analysis, dependability and security, high-performance computation/cloud computing applications, computational biology and chemistry and computational mechanics. The primary goal of this book is to strengthen pre-eminence in computational modeling and simulation by catalyzing the transformative use of innovative developments in a wide range of disciplines to achieve lasting societal impact. The book discusses on how to perform simulation of large complex dynamic systems in an efficient manner using advanced computational analysis. The inter-disciplinary nature of the book would be a valuable reference for academicians and research scientists, industrialists interested in modelling and simulation driven by computational technology.

This essential volume explores a variety of tools and protocols of structure-based (homology modeling, molecular docking, molecular dynamics, protein-protein interaction network) and ligand-based (pharmacophore mapping, quantitative structure-activity relationships or QSARs) drug design for ranking and prioritization of candidate molecules in search of effective treatment strategy against coronaviruses. Beginning with an introductory section that discusses coronavirus interactions with humanity and COVID-19 in particular, the book then continues with sections on tools and methodologies, literature reports and case studies, as well as online tools and databases that can be used for computational anti-coronavirus drug research. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of practical detail and implementation advice that ensures high quality results in the lab. Comprehensive and timely, In Silico Modeling of Drugs Against Coronaviruses: Computational Tools and Protocols is an ideal reference for researchers working on the development of novel anti-coronavirus drugs for SARS-CoV-2 and for coronaviruses that will likely appear in the future.

This book focuses on the problem of responsibility voids: these are cases where responsibility for a morally undesirable outcome cannot be attributed to any of the involved agents. Responsibility voids are thought to occur in collective decision-making and in the context of artificial intelligent systems. In these cases, philosophers worry that there is a shortfall of moral responsibility. In particular, such voids are often assumed to justify a notion of collective responsibility that cannot be reduced to individual responsibility. One of the aims of the book is to study how collective responsibility and joint action relate to individual responsibility and individual actions. The book offers a unifying framework for modelling moral responsibility by drawing from modal logic and game theory. The book investigates the possibility and scope of the problem of responsibility voids. One of its characteristics is its pluralistic perspective on moral responsibility: in contrast to giving a unique and all-encompassing definition of it, the book makes progress by spelling out and modelling several conceptions of moral responsibility. One of the appealing features of the book is that a relatively small range of models is used to investigate a variety of conceptions of moral responsibility. The unifying framework can thus be used to characterize the conditions under which responsibility voids are ruled out.

Aerodynamic design, like many other engineering applications, is increasingly relying on computational power. The growing need for multi-disciplinarity and high fidelity in design optimization for industrial applications requires a huge number of repeated simulations in order to find an optimal design candidate. The main drawback is that each simulation can be computationally expensive - this becomes an even bigger issue when used within parametric studies, automated search or optimization loops, which typically may require thousands of analysis evaluations. The core issue of a design-optimization problem is the search process involved. However, when facing complex problems, the high-dimensionality of the design space and the high-multi-modality of the target functions cannot be tackled with standard techniques. In recent years, global optimization using meta-models has been widely applied to design exploration in order to rapidly investigate the design space and find sub-optimal solutions. Indeed, surrogate and reduced-order models can provide a valuable alternative at a much lower computational cost. In this context, this volume offers advanced surrogate modeling applications and optimization techniques featuring reasonable computational resources. It also discusses basic theory concepts and their application to aerodynamic design cases. It is aimed at researchers and engineers who deal with complex aerodynamic design problems on a daily basis and employ expensive simulations to solve them.

3D Mesh Processing and Character Animation focusses specifically on topics that are important in three-dimensional modelling, surface design and real-time character animation. It provides an in-depth coverage of data structures and popular methods used in geometry processing, keyframe and inverse kinematics animations and shader based processing of mesh objects. It also introduces two powerful and versatile libraries, OpenMesh and Assimp, and demonstrates their usefulness through implementations of a wide range of algorithms in mesh processing and character animation respectively. This Textbook is written for students at an advanced undergraduate or postgraduate level who are interested in the study and development of graphics algorithms for three-dimensional mesh modeling and analysis, and animations of rigged character models. The key topics covered in the book are mesh data structures for processing adjacency queries, simplification and subdivision algorithms, mesh parameterization methods, 3D mesh morphing, skeletal animation, motion capture data, scene graphs, quaternions, inverse kinematics algorithms, OpenGL-4 tessellation and geometry shaders, geometry processing and terrain rendering.

This book explores Autonomic Nervous System (ANS) dynamics as investigated through Electrodermal Activity (EDA) processing. It presents groundbreaking research in the technical field of biomedical engineering, especially biomedical signal processing, as well as clinical fields of psychometrics, affective computing, and psychological assessment. This volume describes some of the most complete, effective, and personalized methodologies for extracting data from a non-stationary, nonlinear EDA signal in order to characterize the affective and emotional state of a human subject. These methodologies are underscored by discussion of real-world applications in mood assessment. The text also examines the physiological bases of emotion recognition through noninvasive monitoring of the autonomic nervous system. This is an ideal book for biomedical engineers, physiologists, neuroscientists, engineers, applied mathmeticians, psychiatric and psychological clinicians, and graduate students in these fields. This book also: Expertly introduces a novel approach for EDA analysis based on convex optimization and sparsity, a topic of rapidly increasing interest Authoritatively presents groundbreaking research achieved using EDA as an exemplary biomarker of ANS dynamics Deftly explores EDA's potential as a source of reliable and effective markers for the assessment of emotional responses in healthy subjects, as well as for the recognition of pathological mood states in bipolar patients

This book explores how environmental urban design can benefit from established and emerging representation and simulation techniques that meet the need for a multisensory approach. Bringing together contributions by researchers and practicing professionals that approach the topics discussed from both theoretical and practical perspectives and draw on case-study applications, it addresses important themes including digital modeling, physical modeling, mapping, and simulation. The chapters are linked by their relevance to simple but crucial questions: How can representational solutions enhance an urban design approach in which people's well-being is considered the primary goal? How can one best represent and design the ambiance of places? What kinds of technologies and tools are available to support multisensory urban design? How can current and future environments be optimally represented and simulated, taking into account the way in which we experience places? Shedding new light on these key questions, the book offers both a reference guide for those engaged in applied research, and a toolkit for professionals and students.

This manual describes the wide range of electromechanical, electrochemical and electro-optical transducers at the heart of current field-deployable ocean observing instruments. Their modes of operation, precision and accuracy are discussed in detail. Observing platforms ranging from the traditional to the most recently developed are described, as are the challenges of integrating instrument suits to individual platforms. Technical approaches are discussed to address environmental constraints on instrument and platform operation such as power sources, corrosion, biofouling and mechanical abrasion. Particular attention is also given to data generated by the networks of observing platforms that are typically integrated into value-added data visualization products, including numerical simulations or models. Readers will learn about acceptable data formats and representative model products. The last section of the book is devoted to the challenges of planning, deploying and maintaining coastal ocean observing systems. Readers will discover practical applications of ocean observations in diverse fields including natural resource conservation, commerce and recreation, safety and security, and climate change resiliency and adaptation. This volume will appeal to ocean engineers, oceanographers, commercial and recreational ocean data users, observing systems operators, and advanced undergraduate and graduate students in the field of ocean observing.

The rapid evolution of computer science, communication, and information technology has enabled the application of control techniques to systems beyond the possibilities of control theory just a decade ago. Critical infrastructures such as electricity, water, trafficand intermodal transport networks are now in the scope of control engineers. The sheer size of such large-scale systems requires the adoption of advanced distributed control approaches. Distributed model predictive control (MPC) is one of the promising control methodologies for control of such systems.

This book provides a state-of-the-art overview of distributed MPC approaches, while at the same time making clear directions of research that deserve more attention. The core and rationale of 35 approaches are carefully explained. Moreover, detailed step-by-step algorithmic descriptions of each approach are provided. These features make the book a comprehensive guide both for those seeking an introduction to distributed MPC as well as for those who want to gain a deeper insight in the wide range of distributed MPC techniques available.

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Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies.

This book presents new results on applications of geometric algebra. The time when researchers and engineers were starting to realize the potential of quaternions for - plications in electrical, mechanic, and control engineering passed a long time ago. Since the publication of Space-Time Algebra by David Hestenes (1966) and Clifford Algebra to Geometric Calculus: A Uni?ed Language for Mathematics and Physics by David Hestenes and Garret Sobczyk (1984), consistent progress in the app- cations of geometric algebra has taken place. Particularly due to the great dev- opments in computer technology and the Internet, researchers have proposed new ideas and algorithms to tackle a variety of problems in the areas of computer science and engineering using the powerful language of geometric algebra. In this process, pioneer groups started the conference series entitled "Applications of Geometric Algebra in Computer Science and Engineering" (AGACSE) in order to promote the research activity in the domain of the application of geometric algebra. The ?rst conference, AGACSE'1999, organized by Eduardo Bayro-Corrochano and Garret Sobczyk, took place in Ixtapa-Zihuatanejo, Mexico, in July 1999. The contri- tions were published in Geometric Algebra with Applications in Science and En- neering, Birkhauser, 2001. The second conference, ACACSE'2001, was held in the Engineering Department of the Cambridge University on 9-13 July 2001 and was organizedbyLeoDorst,ChrisDoran,andJoanLasenby. Thebestconferencecont- butions appeared as a book entitled Applications of Geometric Algebra in Computer Science and Engineering, Birkhauser, 2002. The third conference, AGACSE'2008, took place in August 2008 in Grimma, Leipzig, Germany.

The papers in this volume comprise the refereed proceedings of the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA2008), in Beijing, China, 2008. The conference on the Second IFIP International Conference on Computer and Computing Technologies in Agriculture (CCTA 2008) is cooperatively sponsored and organized by the China Agricultural University (CAU), the National Engineering Research Center for Information Technology in Agriculture (NERCITA), the Chinese Society of Agricultural Engineering (CSAE) , International Federation for Information Processing (IFIP), Beijing Society for Information Technology in Agriculture, China and Beijing Research Center for Agro-products Test and Farmland Inspection, China. The related departments of China's central government bodies like: Ministry of Science and Technology, Ministry of Industry and Information Technology, Ministry of Education and the Beijing Municipal Natural Science Foundation, Beijing Academy of Agricultural and Forestry Sciences, etc. have greatly contributed and supported to this event. The conference is as good platform to bring together scientists and researchers, agronomists and information engineers, extension servers and entrepreneurs from a range of disciplines concerned with impact of Information technology for sustainable agriculture and rural development. The representatives of all the supporting organizations, a group of invited speakers, experts and researchers from more than 15 countries, such as: the Netherlands, Spain, Portugal, Mexico, Germany, Greece, Australia, Estonia, Japan, Korea, India, Iran, Nigeria, Brazil, China, etc.

In this concise yet comprehensive Open Access textbook, future inventors are introduced to the key concepts of Cyber-Physical Systems (CPS). Using modeling as a way to develop deeper understanding of the computational and physical components of these systems, one can express new designs in a way that facilitates their simulation, visualization, and analysis. Concepts are introduced in a cross-disciplinary way. Leveraging hybrid (continuous/discrete) systems as a unifying framework and Acumen as a modeling environment, the book bridges the conceptual gap in modeling skills needed for physical systems on the one hand and computational systems on the other. In doing so, the book gives the reader the modeling and design skills they need to build smart, IT-enabled products. Starting with a look at various examples and characteristics of Cyber-Physical Systems, the book progresses to explain how the area brings together several previously distinct ones such as Embedded Systems, Control Theory, and Mechatronics. Featuring a simulation-based project that focuses on a robotics problem (how to design a robot that can play ping-pong) as a useful example of a CPS domain, Cyber-Physical Systems: A Model-Based Approach demonstrates the intimate coupling between cyber and physical components, and how designing robots reveals several non-trivial control problems, significant embedded and real-time computation requirements, and a need to consider issues of communication and preconceptions.

Recent trends in the fashion market (including an impressive increase in the number of new collections, product assortments and variants, and the emerging mass-customization model) dictate the need for a new approach. "Transforming Clothing Production into a Demand-Driven, Knowledge-Based, High-Tech Industry" discusses the ramifications of such an approach, which must lead to a drastic shortening of the whole cycle from conception to production and retail, as well as a shift from a labor-intensive to a technology- and knowledge-intensive clothing manufacturing industry. "Transforming Clothing Production into a Demand-Driven, Knowledge-Based, High-Tech Industry" is a collection of short papers from prominent researchers involved with the LEAPFROG (Leadership for European Apparel Production From Research along Original Guidelines) initiative. LEAPFROG proposes a revolutionary industrial paradigm based on research results in scientific-technological fields.

The yard block of a container terminal is the central point of synchronisation for asynchronous container flows between deep-sea vessels and transport to the hinterland. The structure of the block stipulates that containers are stacked on top of each other with only the topmost container directly accessible by a yard crane. This book describes a holistic and integrative approach to container handling in yard blocks to optimise productivity by minimising re-handling operations. The results provide insights for academic scholars as well as for experts from practical terminal planning and operations. The approach presented is two-fold: first, a theoretical foundation of the interdependencies in decision-making is established using mathematical programming. Secondly, operations involving uncertain container arrival information are examined on the basis of a simulation with a rigorous experimental design and statistical evaluation. In this context, the book develops container-handling strategies and analyses the impact of a system for vehicle arrival management - the "Terminal Appointment System". The findings presented in this book are the result of a close cooperation with experts at the port of Hamburg and build on previous research.

The authors offer a revolutionary solution to risk management. It's the unknown risks that keep leaders awake at night-wondering how to prepare for and steer their organization clear from that which they cannot predict. Businesses, governments and regulatory bodies dedicate endless amounts of time and resources to the task of risk management, but every leader knows that the biggest threats will come from some new chain of events or unexpected surprises-none of which will be predicted using conventional wisdom or current risk management technologies and so management will be caught completely off guard when the next crisis hits. By adopting a scientific approach to risk management, we can escape the limited and historical view of experience and statistical based risk management models to expose dynamic complexity risks and prepare for new and never experienced events.