Structured Biological Modelling presents a straightforward introduction for computer-aided analysis, mathematical modelling, and simulation of cell biological systems. This unique guide brings together the physiological, structural, molecular biological, and theoretical aspects of the signal transduction network that regulates growth and proliferation in normal and tumor cells. It provides comprehensive survey of functional and theoretical features of intracellular signal processing and introduces the concept of cellular self-organization. Exemplified by oscillatory calcium waves, strategies for the design of computer experiments are presented that can assist or even substitute for time-consuming biological experiments. The presented minimal model for proliferation-associated signal transduction clearly shows the alterations of the cellular signal network involved in neoplastic growth. This book will be useful to cell and molecular biologists, oncologists, physiologists, theoretical biologists, computer scientists, and all other researchers and students studying functional aspects of cellular signaling.

Are you thinking about working in the board game industry? Here's what you need to know. There are so many jobs and roles that need to be filled in the board game industry. You might just have the right skills and experience to excel. But first you need to know what opportunities exist and what the hardest gaps are to fill! In this book, you'll discover * What jobs are really in demand * How you can get your foot in the door with a publisher * Jobs in the industry you've never even thought of * What other opportunities exist for people with skills just like yours With insights from over 40 industry pros, as well as the author's many years of experience, you'll be able to put your own skills and experience to great use in an amazing, growing industry.

Making a great board game and pitching it to publishers are two completely different things. If you've got a game that you want to share with the world but don't know what to do next, this book will help you navigate through exactly what steps to take. You'll discover: How to find the right publisher Exactly what publishers are looking for How to create a sell sheet that will actually sell your game How to negotiate the best deal and get paid more for your game What to look out for in contracts to make sure you don't get exploited You'll learn from Joe's experiences as a full-time board game designer and instructor, along with tips and stories from a dozen other published designers, plus the exact things that publishers want. Direct from 16 established publishers.

Werden Sie im Umgang mit dem Computer noch souveraner Christine Peyton und Olaf Altenhof Kopieren, Einfugen die Tastenkurzel fur diese Aktionen kennen die meisten, aber es gibt noch viele mehr, die Ihnen bei der Arbeit mit Windows und mit den Office-Programmen helfen konnen. Christine Peyton und Olaf Altenhof nennen Ihnen die wichtigsten. Dabei listen sie die Tastenkombinationen nicht einfach auf, sondern erlautern sie auch, mitunter erganzt durch einen Screenshot. Ausserdem erfahren Sie, wie Sie Tastenkurzel fur Ihre ganz speziellen Bedurfnisse selbst erstellen. So geht Ihnen die Arbeit mit Windows, Excel, Word und Co noch schneller von der Hand.

The quick way to learn Microsoft Teams! This is learning made easy. Get more done quickly with Microsoft Teams in any environment, and help your whole team succeed with it. Jump in wherever you need answers-brisk lessons and detailed screenshots show you exactly what to do, step by step. Build your own teams to enhance collaboration Use team channels to bring structure and relevance to your work Work smarter with apps, tabs, extensions, connectors, and bots Create, upload, edit, and share Microsoft 365 documents inside Teams Stay connected via chat and video calls Get more done in every Teams meeting Customize Teams to maximize personal and organizational efficiency Look up just the tasks and lessons you need

Contents:
Generalisation: State of the Art and Issues; GIS-Based Compilation and Generalisation; Three Essential Building Blocks for Automated Generalisation; Data and Knowledge Modelling for Generalisation; Controlling the Effects of Generalisation on GIS Map Manipulations; A Hierarchical top-down bottom-up Approach to Topographic Map Generalisation.

Use Excel 365 and Excel 2021 core features to build spreadsheets that solve business problems and deliver reliable answers. Drawing on his unsurpassed experience, Paul McFedries helps you make the most of formulas and functions, including recent improvements ranging from dynamic arrays to XLOOKUP and LET. McFedries' step-by-step projects walk you through handling key tasks, from building timesheets to projecting cash flow and aging receivables. His practical examples and clear instructions demystify intermediate-to-advanced-level formula construction, and help you leverage Excel's most useful functions in your everyday work. Becoming an Excel expert has never been easier! By reading this book, you will: Improve business analyses by adding intelligence and knowledge to your models Replace cumbersome formulas with convenient predefined functions Use modern lookups to make your formulas more powerful and flexible Simplify complex calculations with dynamic arrays in Excel 365 and Excel 2021 Use conditional formatting to reveal anomalies, problems, or opportunities Calculate loan payments, interest costs, terms, and amortization schedules Project the future value of investments, and plan to achieve investment goals Master essential discounting and cash-flow analysis tools, including NPV and IRR Sort, filter, and analyze any tabular data, from customers to inventory Easily analyze huge datasets with PivotTable calculations Perform sophisticated what-if analyses, scenario planning, and forecasting Optimize profit, cost, or operational efficiency with Solver About This Book For everyone who wants to get more done with Microsoft Excel in less time For business and financial professionals, entrepreneurs, students, and others who need to efficiently manage and analyze data

Crafted to resemble a set of Abstergo case files, this immersive and interactive book provides a glimpse into the technology that allows characters to inhabit the lives of their ancestors - a cornerstone of the Assassin's Creed narrative. In-depth and beautifully illustrated, the Assassin's Creed Manual will grant a never-before-seen look at the inner workings of the fictional corporation at the heart of the blockbuster franchise.

Highlighting and illustrating several important and interesting theoretical trends that have emerged in the continuing development of instructional technology, this book's organizational framework is based on the notion of two opposing camps. One evolves out of the intelligent tutoring movement, which employs artificial-intelligence technologies in the service of student modeling and precision diagnosis, and the other emerges from a constructivist/developmental perspective that promotes exploration and social interaction, but tends to reject the methods and goals of the student modelers. While the notion of opposing camps tends to create an artificial rift between groups of researchers, it represents a conceptual distinction that is inherently more interesting and informative than the relatively meaningless divide often drawn between "intelligent" and "unintelligent" instructional systems.
An evident trend is that researchers in both "camps" view their computer learning environments as "cognitive tools" that can enhance learning, performance, and understanding. Cognitive tools are objects provided by the instructional environment that allow students to incorporate new auxiliary methods or symbols into their social problem solving which otherwise would be unavailable. A final section of the book represents researchers who are assimilating and accommodating the wisdom and creativity of their neighbors from both camps, perhaps forming the look of technology for the future. When the idea of model tracing in a computer-based environment is combined with appreciation for creative mind-extension cognitive tools and for how a community of learners can facilitate learning, a camp is created where AI technologists and social constructivist learning theorists can feel equally at home.

This text provides a reference on the early 1990s state of the art in this field covering topics such as physics, chemistry, toxicology and human behaviour. It contains nearly 100 scientific papers on all aspects of the subject. Many papers are included which illustrate the early 1990s state of development in the mathematical modelling of fire phenomena using computing.

Discover every weapon from the world of Destiny in this comprehensive visual guide, loaded with stunning artwork! From the Thorn and Hawkmoon hand cannon, to the Outbreak Perfected rifle, the Destiny video games feature an incredible arsenal of weaponry. Now, fans of the hit series can experience these weapons like never before, with this definitive guide to the weapons of Destiny. Featuring photorealistic art from both the original game and Destiny 2, this book will be the ultimate word on the weapons of Destiny.

Although GIS has been in existence for over 20 years, the systems have only recently matured to the point where they have become accessible to geographers, planners, environmental scientists and others as an affordable and practical tool for spatial analysis. Much of the GIS literature is scattered over the journals and technical reports of a number of disciplines. These sources are often not widely available especially to the newcomer to the field. This text was assembled to bring together what we believe is a balanced sampling of written works that cover important aspects of the basic principles involved in GIS, as well as to provide some examples of GIS applications.

Discover all of the Exotic weapons from the world of Destiny 2 in this comprehensive visual guide, loaded with stunning artwork! From the Thorn and Hawkmoon hand cannon, to the Outbreak Perfected rifle, Destiny 2 features an incredible arsenal of exotic weaponry. Now, fans of the hit series can experience these weapons like never before, with this definitive guide to the exotic weapons of Destiny 2. Featuring magnificent art from Destiny 2, it is the ultimate book on the most unique weapons in Destiny 2. BEAUTIFUL EXOTIC WEAPON ARTWORK: From the Thorn and Hawkmoon hand cannon, to the Outbreak Perfected rifle, this book features the beautiful art of Destiny 2. The incredible detail of the illustrations featured in this book will give fans an unparalleled experience of the entire Destiny 2 exotic weapon arsenal. OWN THE DEFINITIVE DESTINY 2 EXOTIC WEAPONS GUIDE: This book will be the ultimate word on the exotic weapons of Destiny 2. COMPLETE YOUR DESTINY LIBRARY: Destiny: The Exotic Collection, Volume One stands alongside fan-favorite books such as Destiny: The Official Cookbook and Art of Destiny Volume One and Two.

This book offers examples of programs designed for analysis of variance and related statistical tests of significance that can be run with SPSS. The reader may copy these programs directly, changing only the names or numbers of levels of factors according to individual needs. Ways of altering command specifications to fit situations with larger numbers of factors are discussed and illustrated, as are ways of combining program statements to request a variety of analyses in the same program. The first two chapters provide an introduction to the use of SPSS, Versions 3 and 4. General rules concerning the use of commands, subcommands, and keywords are discussed, providing a specific introduction to the use of SPSS for analysis of variance. They provide detailed programs for obtaining omnibus F tests in completely randomized designs and for designs that include repeated measures factors. The remaining chapters may be read independently and in any order.

The Art of Game Design guides you through the design process step-by-step, helping you to develop new and innovative games that will be played again and again. It explains the fundamental principles of game design and demonstrates how tactics used in classic board, card and athletic games also work in top-quality video games. Good game design happens when you view your game from as many perspectives as possible, and award-winning author Jesse Schell presents over 100 sets of questions to ask yourself as you build, play and change your game until you finalise your design. This latest third edition includes examples from new VR and AR platforms as well as from modern games such as Uncharted 4 and The Last of Us, Free to Play games, hybrid games, transformational games, and more. Whatever your role in video game development an understanding of the principles of game design will make you better at what you do. For over 10 years this book has provided inspiration and guidance to budding and experienced game designers - helping to make better games faster.

Increase the photorealism of your 3d visualizations with enhanced toolsets of V-Ray 5 for 3ds Max 2020. The book is filled with colorful illustrations depicting step-by-step tutorials about the process of creating a photorealistic day-and-night exterior scene. Each tutorial includes a 3d project scene to guide users through the production and the post-production processes. The book begins with an overview of the best techniques to approach clients via emails, calls, meetings, and via social media. There are also key insights into the best practices of handling projects, pricing, contracts, invoices, the pre-production, production, and the post-production, to name but a few. Throughout the book, users are taken through VRayMtl functions such as Diffuse, Roughness, Reflect, Glossiness, Metalness, Refract, Index of Refraction (IOR), Abbe number, Fog color, Translucency, BRDF, Coat, Sheen, and Bump. Also, users will learn how to use procedural maps such as VRayBitmap, VRayTriplanarTex, Bricks, Metals, Carpaint, VRayDisplacementMod, VRayUVWRandomizer, VRayMultiSubTex, VRayPointCloudColor, VRayDirt, VRayAerialPersepective, VRayLightMtl, VRayMtlWrapper, VRayOverrideMtl, VRay2SidedMtl, VRayBlendMtl, and VRayEdgesTex. In addition, there are tips and tricks accompanied with videos highlighting how to create VR interactive apps using Verge 3d; how to create verified views; and how to use plug-ins and scripts such as Project Manager, Auto grid pivot point, GarageFarm, Zmapping, gobotree, and VIShopper. Finally, users will have a rare insight into all functionalities of a VRay camera, VRayLight objects, Render settings, Frame buffer, Global switches, IPR options, Bucket and Progressive image samplers, Image filters, Global DMC, Color mapping, Brute force global illumination, Light cache, Color management, Distributed rendering, Render elements, VRay image file format, VFB History settings, VFB Lens Effects, LightMix, Film tonemap, Hue/Saturation, Lookup Table, and much more. Key Features This book deals with real projects/3d scenes and delivers up-to-date V-Ray 5 functionalities and production workflows using 3ds Max 2020 This book has professional supporting files ready to open and explore This book details the meticulous step-by-step processes of creating jaw-dropping 3d renderings This book includes unrivaled in-depth coverage of V-Ray 5 for 3ds Max 2020 This book includes 3d rendering methodologies currently used by key industry players Author Jamie Cardoso is a renowned author, reviewer, computer artist, and technologist, with years of experience in creating state-of-the-art 3d photomontages, verified views, VR, AR, XR, MR, Stereos, and photorealistic interior and exterior visualizations for architects and designers.

* Targests readers with a background in programming, interested in an introduction/refresher in statistical hypothesis testing * Uses Python throughout * Provides the reader with the opportunity of using the book whenever needed rather than following a sequential path.

This book takes the practicality of other "Gems" series such as "Graphics Gems" and "Game Programming Gems" and provide a quick reference for novice and expert programmers alike to swiftly track down a solution to a task needed for their VR project. Reading the book from cover to cover is not the expected use case, but being familiar with the territory from the Introduction and then jumping to the needed explanations is how the book will mostly be used. Each chapter (other than Introduction) will contain between 5 to 10 "tips", each of which is a self-contained explanation with implementation detail generally demonstrated as pseudo code, or in cases where it makes sense, actual code. Key Features Sections written by veteran virtual reality researchers and developers Usable code snipits that readers can put to immediate use in their own projects. Tips of value both to readers entering the field as well as those looking for solutions that expand their repertoire.

This study surveys the approaches used and problems encountered in the modelling of real geophysical data. It addresses key themes of the modelling process including the selection of reliable data, the choice of data structure and the objective analysis of 3-D information presented in the model.

Game AI Pro2: Collected Wisdom of Game AI Professionals presents cutting-edge tips, tricks, and techniques for artificial intelligence (AI) in games, drawn from developers of shipped commercial games as well as some of the best-known academics in the field. It contains knowledge, advice, hard-earned wisdom, and insights gathered from across the community of developers and researchers who have devoted themselves to game AI. In this book, 47 expert developers and researchers have come together to bring you their newest advances in game AI, along with twists on proven techniques that have shipped in some of the most successful commercial games of the last few years. The book provides a toolbox of proven techniques that can be applied to many common and not-so-common situations. It is written to be accessible to a broad range of readers. Beginners will find good general coverage of game AI techniques and a number of comprehensive overviews, while intermediate to expert professional game developers will find focused, deeply technical chapters on specific topics of interest to them. Covers a wide range of AI in games, with topics applicable to almost any game Touches on most, if not all, of the topics necessary to get started in game AI Provides real-life case studies of game AI in published commercial games Gives in-depth, technical solutions from some of the industry's best-known games Includes downloadable demos and/or source code, available at http://www.gameaipro.com

This book introduces the basics in game usability and overall game UX mindset and techniques, as well as looking at current industry best practices and trends. Fully updated for its second edition, it includes practical advice on how to include usability in already tight development timelines, and how to advocate for UX and communicate results to higher-ups effectively. The book begins with an introduction to UX strategy considerations for games, and to UX design, before moving on to cover core user research and usability techniques as well as how to fit UX practices into the business process. It provides considerations of player differences and offers strategies for inclusion as well as chapters that give platform and context specific advice. With a wealth of new interviews with industry leaders and contributions from the very best in game UX, the book also includes brand new chapters on: Accessibility Mobile Game Usability Data Science Virtual and Augmented Reality Esports This book will be vital reading for all professional game developers and game UX advocates, as well as those students aspiring to work in game development and game UX.

Game Audio with FMOD and Unity introduces readers to the principles and practice of game audio through the process of creating their own First Person Shooter (FPS) game. All the basics are covered, as well as a simple introduction to coding. Using the free software Unity and FMOD Audio Middleware, the reader will be able to create a game of their own and develop a portfolio that demonstrates their capacities in interactive sound design. Perfect for classroom use or independent study, Game Audio with FMOD and Unity also comes with a full suite of audio assets provided on a companion website.