The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer. Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care. Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.

Acing the GI Board Exam: The Ultimate Crunch-Time Resource has been updated into a Second Edition. The Second Edition contains new vignettes, a discussion on Maintenance of Certification Exam (MOC), and discussion on test relevancy for residency rotations! In today's fast-paced world, gastroenterology and hepatology residents and fellows struggle to find the time to study for the board exams, prepare for the recertification exam, prepare for teaching rounds, or just plain read. What is the best way to effectively prepare and study, if reading multiple resources can't seem to fit into your daily schedule? The answer to your study questions (and study time!) can be found inside the newly updated Second Edition of Acing the GI Board Exam: The Ultimate Crunch-Time Resource! Why You Will Need to Read Acing the GI Board Exam, Second Edition: New! 41 new and carefully vetted board-style vignettes with color images New! Brief discussion on the Maintenance of Certification Exam (MOC) New! Discussion on test relevancy for residency rotations Comprehensive yet succinct answers using a high-yield format Emphasis on key clinical pearls and "board buzzwords" Answers to classic board "threshold values" questions that you need to know but always seem to forget Rapid-fire, crunch-time exam with 195 classic one-liners Dr. Brennan M. R. Spiegel has collected every pearl of wisdom, high-yield factlet, ""Board buzzword,"" micrograph, and classic imaging study he could muster, all while keeping Acing the GI Board Exam: The Ultimate Crunch-Time Resource, Second Edition a manageable size. Acing the GI Board Exam, Second Edition fills the unmet need in board review by presenting time-tested and high-yield information in a rational, useful, and contextually appropriate format suitable studying for the board exams and preparing for the recertification exam. Chapters Include: A compilation of general lessons learned from past test-takers "Tough Stuff" board review vignettes Board review "Clinical Threshold Values" "Crunch-Time" Self-Test and Answer Guide-time to get your game on! With its focus on pearl after pearl, emphasis on images, and attention to high-yield "tough stuff" vignettes you don't know the answers to (yet), Acing the GI Board Exam, Second Edition is truly the ultimate crunch-time resource for acing the GI and Hepatology examination, taking recertifying examinations, looking good on clerkship rounds, or for just challenging yourself with interesting and entertaining vignettes.

'A must-have for sufferers, medics, caterers and restaurant staff' - Ian Marber This authoritative, accessible and supportive book will help you to find out if you or child need to avoid gluten, and how to set about getting a diagnosis. If you do need to avoid gluten - or if you already know you or a family member are coeliac - it will help you to understand labelling, to shop safely (and affordably), to eat out without fear, and to make the best healthy, gluten-free choices for your diet. There is plenty of psychological and emotional support, and insight into managing everyday challenges, from safe travel to personal care and other non-food exposures. The book also gives some insight into the latest research into coeliac disease, and possible future developments for managing the condition, giving continued hope that the newest, groundbreaking therapies may transform the lives of coeliacs ten years hence. Practical, readable and with a Foreword by Coeliac UK, this book is indispensable for anyone seeking the very latest information and advice on how to live the best possible gluten-free life.

This volume provides in a conveniently accessible package a comprehensive collection of accurate and timely information on the management of patients with diarrhea, both in pediatric age and in the adult. As medical knowledge has recently expanded in this area, this volume is full of new practical, clinically useful material for the busy clinician. Illustrations are emphasized to permit rapid acquisition of practical information that is not readily available in the major texts. Each chapter is concise, concentrating on "clinical pearls," and new advances in diagnostic and therapeutic technology. Each chapter discusses the relative costs of diagnostic and therapeutic options to permit financial considerations to be taken into account in the decision making process. Additional unique features include, summaries of key points, recommendations, and indications for requesting GI subspecialty consultation. Providing a comprehensive but practical overview of the issues surrounding the diarrheal diseases, this volume will prove of great value and utility to gastroenterologists, surgeons, internists, primary care physicians.

Bariatric surgery has led to improved health outcomes including significant weight loss and reduction in co-morbidities among patients with obesity. Clinical practice guidelines recommend that patients considering bariatric surgery undergo a comprehensive nutritional assessment. Nutrition and Bariatric Surgery is the first comprehensive book that uniquely addresses the dietary and nutritional care of the bariatric surgery patient. This book reviews the nutritional and physiological changes imposed by surgical revision of the gastrointestinal tract. Also discussed are nutritional assessment of the bariatric surgical patient as well as pre- and postoperative dietary management recommendations. Other clinical topics covered include nutritional anemia, metabolic bone disease, neurological disorders, and protein-calorie malnutrition. Nutrition and Bariatric Surgery examines eating behaviors before and after bariatric surgery as well as psychological issues, mood disorders, and nutritional concerns associated with weight regain. The book also addresses nutritional needs of special populations undergoing bariatric surgery including adolescents, pregnant or lactating women, and severely obese ICU patients. The book is an authoritative guide for health care professionals caring for the bariatric patient including physicians, dietitians, physician assistants, nurses, and nurse practitioners.

Few human illnesses today are so challenging, medically, scientifically, and socio-economically, as the "nonspecific" inflammatory bowel diseases (IBD): ulcerative colitis and Crohn's disease. Originating several centuries ago but essentially diseases of the 20th century, often attacking children and young adults, involving all bodily systems as well as the gastrointestinal tract, ulcerative colitis and Crohn's disease have emerged in recent decades as among the more "glamorous" unsolved diseases, presenting unusual opportunities for insightful clinical and investigative study. Many of the prevailing concepts originated during the early and mid 20th century. The purpose of Origins and Directions of Inflammatory Bowel Disease is to review these earlier studies and their evolution "from the mystical to the molecular," and guide investigators and physicians through the challenging clinical and scientific maze of IBD.

Offering 171 unique cases, Gastrointestinal Imaging Cases features over 700 high-quality images. The clinically relevant cases cover both benign and malignant conditions and are grouped into 12 sections organized by the parts of the Gastrointestinal System including: the Pharynx and Esophagus, Stomach, Duodenum, Small Intestine, Appendix, Colon, Rectum, and Anus, Liver, Gallbladder, Bile Ducts, Pancreas, Spleen, and Mesentery and Peritoneum. Within each section, the cases appear in a random order to facilitate the self-assessment experience of reading cases as unknowns. Each case is complete with pertinent findings, differential diagnoses, management recommendations, teaching points, and suggested further reading. This comprehensive, yet easy-to-follow, casebook is an ideal tool for the resident preparing for the boards, the fellow for recertification exams, or the radiologist in need of a quick review.

From a Harvard Medical School dream team-the most important insights on managing digestive and hepatic diseases in the palm of your hand Presented in a streamlined, templated style that makes learning and retaining key information effortless, CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, and Endoscopy, Fourth Edition offers authoritative insights for accurately diagnosing and effectively treating digestive tract and liver disorders. This peerless guide delivers authoritative coverage of the entire spectrum of gastroenterology and hepatology conditions, from stomach and esophageal to pancreatic and liver disorders, with very chapter outlining the essentials of diagnosis for each condition. Logically organized, the book begins with a section on general concerns, such as acute abdominal pain, and progresses to specific disease categories. High-yield overview of an effective treatment approach for chronic hepatitis C provides key perspectives on improving patient outcomes. Features 90+ full-color endoscopic and radiographic images enhance clinical decision-making and clarify imaging techniques Essentials of Diagnosis provide at-a-glance review of both common and rare digestive disorder Updated references to recently-published clinically relevant articles Includes continued coverage of the revised national guidelines

Ischemic colitis is becoming increasingly one of the most important conditions involving the colon. This is due to a combination of multiple factors: (1) increasing age of the world population due to improved public health conditions and advances in medicine; (2) diagnostic advances in recognizing the condition; and, (3) education of physicians who suspect the disease in elderly individuals with colonic symptoms. The disease is a great masquerader of other conditions and can be mistaken for ulcerative colitis, Crohn's disease or almost any other inflammatory disease of the large bowel. It can have shallow ulcers, deep ulcers, filiform polyps, and pseudomembrane. It can produce fistulae or toxic megacolon. The thumb printing and other acute findings are not always seen and the site of involvement may be atypical. It is therefore so important to have a book dealing with this condition extensively and in detail. This scholarly presentation based on large clinical experience significantly contributes to the knowledge of this important disease that will assume even more importance as other conditions involving the colon are successfully treated. As physicians, radiologists and even pathologists have difficulty in diagnosing this condition that appears under multiple guises the information contained here should be invaluable. Alexander R. Margulis, M. D. March 1984, San Francisco PREFACE First of all, I would like to congratulate the authors on their successful publication of this monograph with many diagnostic radiographs of new touch taken by the modern technique."

It gives me great pleasure to have this opportunity to write a Foreword for this new book. In the past two decades we have witnessed very significant advances in the management of the very ill patient. The great success in this field of medical endeavour is largely due to the establishment of intensive care units, but a great deal of progress can also be attributed to the major developments in technology, which affect patient management and care as well as the many sophisticated techniques of diagnosis and patient monitoring. Imaging and Labelling Techniques in the Critically III covers this new important and difficult field of diagnosis and visual monitoring. By establishing the criteria and algorhythms for the choice of the different methods available for this purpose, defining the diagnostic signs on images and resolving some of the mis conceptions and pitfalls, this book will go a long way to help the reader, particularly those involved in the care of patients in the intensive care units. This book brings together many different methods of investigation and discusses the advantages and limitations of these techniques in different clinical circumstances. Some of the techniques are well established and their usefulness in the intensive care unit is in no doubt. Some of the newer techniques such as PET scanning or NMR imaging have not yet found a defined position of usage in the critically ill patient. There is, however, little doubt that in due course this situation will change.

The Bloomsbury Series in Clinical Science is growing and changing. Its Editorial Board and contributors were all originally selected from, or had links with, the University College and Middlesex School of Medicine. Now, as the Series develops, board members and con tributors alike identify with the wider reaches of Bloomsbury and Islington. The aims of the Series remain, however, to highlight, to review and to record significant areas of research and development in the field of clinical science. All contributors are experts in their particular field and monographs may be the work of a single author or several, guided by individual editors. Diseases in the Homosexual Male is the third monograph in the Series. Edited by Michael Adler, Professor of Genito-Urinary Medicine at the University College and Middlesex School of Medicine, it presents contributions from a number of distinguished workers with special expertise. AIDS has perhaps highlighted the problem but this monograph illustrates the wider profile and gives wit ness to the multidisciplinary nature of clinical science."

Many gastroenterologists are presented with patients complaining of one or more of several anorectal symptoms. Patients expect that a gastroenterologist can treat their symptomatic hemorrhoids or anal fissures or diagnose accurately their rectal bleeding. Today the evaluation and treatment of these common ailments is not included within the core curriculum of most gastrointestinal fellowship training programs, and therefore has not been incorporated into a typical GI practice. Diagnosis and Management Guide for Anorectal Disease: A Clinical Reference looks to fill that void. Dr. Waqar Ahmed Qureshi states that most of these perianal and anorectal problems can be successfully treated non-surgically. Diagnosis and Management Guide for Anorectal Disease: A Clinical Reference reviews a number of diseases that gastroenterologists should be able to effectively manage in their office, which eliminates extra cost, inconvenience, and frustration for their patients. A few of the topics that can be found inside: Anatomy and Examination Anatomy and Physiology of the Pelvic Floor Benign Anorectal Conditions Hemorrhoids, Anal Fissures, and Anal Pruritus Benign Soft Tissue, Perianal, Perineal, and Complicated Conditions Pilonidal Disease, Aanorectal IBD Management, and Defecation Disorders Neoplasms Anal Carcinoma and screening high-risk groups The gastroenterologist occupies a unique position between conservative treatment offered by primary care physicians and the more invasive procedures offered by the surgeon. Diagnosis and Management Guide for Anorectal Disease: A Clinical Reference is designed to provide a comprehensive understanding of anorectal diseases that they can manage and, therefore, improve the care of their patients in one comprehensive volume.

The Handbook of Electrogastrography is the first textbook dedicated to reviewing the physiology of gastric myelectrical activity and the measurement of this electrical activity with electrodes placed on the abdominal surface - the electrogastrogram. The Handbook is divided into three major sections. The first section (Chapters 1-3) focuses on the history of electrogastrography, electrical activity of the interstitial cells of Cajal, the cells from which gastric electrical rhythmicity emanates. The cellular level of gastric electrical rhythmicity provides an understanding of the physiological basis of the electrogastrogram signal.

The second major section of the book (Chapters 4-6) incorporates the practical aspects of recording a high quality electrogastrogram and approaches to the analysis of the electrogastrogram using visual inspection and computer techniques. This section focuses on the authors' combined experience of examining EGG recordings for more than sixty years. From this rich research and clinical experience, the clinical application of EGG recordings in an approach to patients with unexplained nausea and vomiting is described. Neuromuscular disorders of the stomach involving gastric dysrhythmias are reviewed.

The third major section of the book (Chapters 7-9) comprises many examples of gastric dysrythmias ranging from bradygastrias to tachygastrias and mixed dysrythmias. Current understanding of the mechanisms of gastric dysrhythmias is reviewed. Artifacts in the EGG signal, which may be confused with gastric dysrhythmias, are also presented.

The Handbook of Electrogastrography will be a valuable reference for physicians interested in recording gastric electrical activity in clinical practices or in clinical research. Gastroenterologists, internists, psychologists and others with an interest in gastric myoelectrical events will also find extensive and relevant information for recording and interpreting EGGs in the Handbook.

This book aims to examine all immunohistochemical and molecular pathological biomarkers that can be useful and effective in patient diagnosis, prognosis and treatment decision, especially when faced with a carcinoma of unknown primary. For this purpose, epithelial malignancies of all systems and related biomarkers are examined one by one, and to look at the subject through the metastatic regions window, biomarkers that can be used to determine the primary focus for carcinomas seen in the areas most frequently metastasized are emphasized. With this bi-directional perspective, the reader is able to find biomarkers of any type of carcinoma on a system basis, as well as access to which biomarkers can be used when faced with a metastatic carcinoma. The importance of biomarkers in patient follow-up and treatment is also conveyed through the clinician's eye, and so biomarkers are handled with a holistic approach in all aspects. This book primarily targets pathologists, as well as clinicians (oncologists and surgeons) who manage cancer patients.

This book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans. Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic. Building on general ecological principles, the book aims to help the reader to understand how the microbiota is formed, how it works, and what the consequences are to humans. Understanding the Gut Microbiota focuses on conceptual progress made from studies of the human bowel microbiota. Where appropriate, it draws on knowledge obtained from other animal species to provide conceptual enlightenment, but this is essentially a book about humans and their bowel microbes. Particular research approaches are recommended to fill knowledge gaps so that fundamental ecological theory and information about the microbiota can be translated into benefits for human health. The relationship between food for humans and resulting food for bowel bacteria emerges as an important topic for consideration. This concise scholarly treatise of the microbiota of the human bowel will be of great interest and use as a text and reference work for professionals, teachers and students across a wide range of disciplines, including the health sciences, general biology, and food science and technology. The provision of handy explanation of terms means that those with a general interest in science can also read the book with enjoyment.

Selected as a Doody's Core Title for 2022! Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily "scope-side guide," it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report. More than 1,600 high-quality photomicrographs capture the subtle morphologic spectrum of neoplastic processes of the tubular GI tract. Each image is captioned with key diagnostic considerations and includes call-outs showing subtle features and diagnostic clues. Practical tools throughout the text include: Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options o Discussions of how and when to incorporate molecular tools o Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports Relevant endoscopic images, photographs of select gross specimens, and medical figures Brief reviews of normal histology that provide contrast to succeeding patterns "Pearls and Pitfalls" and "Near Misses" sections with lessons from real life sign-out experience "Frequently Asked Questions" sections that discuss common diagnostic dilemmas "Sample Note" sections that offer a template of how to synthesize complicated or especially challenging topics Quizzes in every chapter that provide experience with high-yield, board-style teaching topics Enhance Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

This book provides a comprehensive state-of-the art overview on the main trends in the newest endoscopic, robotic, and minimal invasive surgical innovations. It also aims to give insight on some of the innovative ideas around Gastro-intestinal Surgery and Endoscopy to stimulate further activities. It contains established knowledge in the field of endoscopic and surgical techniques, and the integration of these new findings in updated therapeutic decision making are demonstrated. The text reviews the latest literature on the subjects and describes the decision making to establish new therapeutic options in the management of diseases applying new technologies. These new techniques are described in detail, which provide excellent back-up information for clinicians in daily practice. Written by experts in the field, Innovative Endoscopic and Surgical Technology in the GI Tract is a valuable resource of knowledge for clinicians, surgeons, nurses, technicians, students and researchers with an interest in GI- disease.

Recent discoveries and clarifications of known information about the mesentery have now established that these complex structures function together as an individual organ within the human body. As such, conditions that affect the mesentery can now be grouped within a single area of study and clinical practice. The various aspects of mesenteric diseases have not been brought together in a single source and this book aims to bring them together for the first time. It will cover general areas such as anatomy, histology and physiology of the mesentery. A description of diagnostic procedures used to evaluate patients with mesenteric disorders will follow. A practical survey with detailed descriptions of medical, surgical, and neoplastic disorders of the mesentery is also be included. This book is intended to be a guide for clinical practitioners including gastroenterologists, general surgeons, colorectal surgeons, primary care physicians, nurse practitioners and physician assistants who manage patients with mesenteric disorders.

This book opens with an introduction to the main purpose and tasks of the GIANA challenge, as well as a summary and an analysis of the results and performance obtained by the 20 participating teams. The early and accurate diagnosis of gastrointestinal diseases is critical for increasing the chances of patient survival, and efficient screening is vital for locating precursor lesions. Video colonoscopy and wireless capsule endoscopy (WCE) are the gold-standard tools for colon and intestinal tract screening, respectively. Yet these tools still present some drawbacks, such as lesion miss rate, lack of in vivo diagnosis capabilities, and perforation risk. To mitigate these, computer-aided detection/diagnosis systems can play a key role in assisting clinicians in the different stages of the exploration. This book presents the latest, state-of-the-art approaches in this field, and also tackles the clinical considerations required to efficiently deploy these systems in the exploration room. The coverage draws upon results from the Gastrointestinal Image Analysis (GIANA) Challenge, part of the EndoVis satellite events of the conferences MICCAI 2017 and 2018. Each method proposed to address the different subtasks of the challenges is detailed in a separate chapter, offering a deep insight into this topic of interest for public health. This book appeals to researchers, practitioners, and lecturers spanning both the computer vision and gastroenterology communities.

This book provides a concise, state-of-the-art overview of occult GI bleeding. The text reviews the epidemiology, screening and detection methods for localization, and prominent treatment strategies for occult GI bleeding. It also features a dedicated section on special patient populations including children, premenopausal women, older adults, and patients with other predisposing, and complicating medical conditions. This volume is supplemented with numerous color illustrations, photographs, and table, and is one of the few dedicated resources on occult GI bleeding. Written by experts in the field, Management of Occult GI Bleeding: A Clinical Guide is a valuable resource for clinicians, practitioners, and students who are involved in the treatment of patients with occult GI bleeding.

This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader's theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world's leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.

For Kathleen Nicholls, life with Crohn's disease has been a constant battle against her bowels. But life has also been about David Bowie, dancing, and laughter. Go Your Crohn Way follows the highs and lows of Kathleen's experiences, and is full of useful advice for maintaining self-confidence and positivity while navigating the world of work, relationships, and those conversations. Warm and inspiring, this book demonstrates how Crohn's can be life-changing, but not just for the worse. Kathleen gives advice and tips on adapting and thriving through Crohn's, including a specially created phrasebook, which proves that so long as you know how to ask for the nearest bathroom, globe-trotting is still firmly on the agenda. Full of fun and humour, Kathleen's journey through life with Crohn's disease will leave you - like her - in stitches.