This innovative handbook bridges the gap between the colorectal surgeon, the stoma nurse and the dermatologist. It addresses the questions of what pathology is involved, what can be done by nurses, when to refer to a dermatologist, and what can be done by a dermatologist. Now in its second edition, the book has been revised throughout and contains new information on nutrition and child stoma patients.

Acute pancreatitis is a common cause of acute abdomen. Diagnoses is difficult as the symptoms mimic that of many other medical and surgical conditions. Patients with severe acute pancreatitis can develop multiple organ failure and need intensive care. As its management is multi-disciplinary involving gastroenterologists, radiologists and surgeons, this book shall appeal to every doctor, irrespective of the specialty. This focused book conveys the knowledge of the basic concepts of acute pancreatitis in an innovative way. Original photographs and figures are used for the better understanding of the readers. In this pocketbook, various aspects related to acute pancreatitis are covered in a unique, simple and easy-to-read A-to-Z format and will be useful to medical students, post-graduate trainees and practicing doctors as a ready reckoner for pancreatitis. Key Features: * Innovative and unique A - Z format. * focuses on signal knowledge and fast clinical management of various facets of different types of acute pancreatitis. * Comprehensive approach with interesting facts. * Lucid and self-explanatory text. * Can be used as a ready reckoner pocketbook .

A practical handbook on fecal microbiota transplantation (FMT) for physicians, nurses, physician assistants, students, residents, and fellows, The 6 Ds of FMT: A Primer for Clinicians from Decision to Discharge and Beyond provides a clinical framework to understand and administer this treatment as safely and effectively as possible. FMT has emerged as a promising treatment for C. difficile infection (CDI), and there is a major need for educational resources on the topic. Drs. Jessica Allegretti, Zain Kassam, and their expert contributors are leaders in the field and have collectively cared for thousands of patients suffering from recurrent CDI who have benefitted from FMT. This guide provides practical tools, clinical pearls, and answers to frequently asked questions. Beginning with introductory information on the microbiome and exploring the history of FMT, The 6 Ds of FMT outlines a step-by-step checklist for administering FMT: Decision: Who is the right CDI patient to receive FMT? What clinical questions should you ask patients in your FMT clinical assessment? Donor: How do you select and screen a donor for FMT? Discussion: What are the risks, benefits, and alternatives that need to be discussed with patients? Delivery: What is the best delivery method for FMT - colonoscopy, nasogastric tube, enema, or capsules? Discharge and follow-up: What is the ideal post-FMT care? How should you council patients following FMT? Discovery: What are the most promising emerging clinical applications for FMT? What is the evidence for FMT in obesity, autism, irritable bowel syndrome, inflammatory bowel disease, antibiotic resistant bacteria, and liver disease? Arming healthcare professionals with the ability to answer questions from patients regarding FMT and the microbiome, The 6 Ds of FMT provides a pragmatic guide for this exciting treatment.

Advanced Nutrition and Dietetics in Gastroenterology provides informative and broad-ranging coverage of the relation between nutrition and diet and the gastrointestinal tract. It explores dietary factors involved in causation of a variety of gastrointestinal disorders, as well as the effects on diet and the treatments available. It also provides an overview of anatomy and physiology, measurement and assessment of function, and dietary components relevant to gastrointestinal health. ABOUT THE SERIES Dietary recommendations need to be based on solid evidence, but where can you find this information? The British Dietetic Association and the publishers of the Manual of Dietetic Practice present an essential and authoritative reference series on the evidence base relating to advanced aspects of nutrition and diet in selected clinical specialties. Each book provides a comprehensive and critical review of key literature in its subject. Each covers established areas of understanding, current controversies and areas of future development and investigation, and is oriented around six key themes: Disease processes, including metabolism, physiology, and genetics Disease consequences, including morbidity, mortality, nutritional epidemiology and patient perspectives Nutritional consequences of diseases Nutritional assessment, drawing on anthropometric, biochemical, clinical, dietary, economic and social approaches Clinical investigation and management Nutritional and dietary management Trustworthy, international in scope, and accessible, Advanced Nutrition and Dietetics is a vital resource for a range of practitioners, researchers and educators in nutrition and dietetics, including dietitians, nutritionists, doctors and specialist nurses.

Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: * Introduction of drug class * Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations * Dosing information for each GI condition and on- and off-label use * Consistent use of both generic and trade names throughout * Specific reference to drug use in pediatric patients and during pregnancy Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists.

This book covers all aspects of small intestinal disease with the aim of providing an up-to-date reference of the highest quality that will assist in everyday clinical practice. After introductory chapters on anatomy, pathophysiology, epidemiology, and signs and symptoms, the roles of different imaging modalities in the diagnosis of small intestinal disease are clearly explained, focusing particularly on capsule endoscopy, device-assisted enteroscopy, CT and MR enterography, and nuclear medicine techniques. A series of chapters then address each of the diseases and conditions that may be encountered. The coverage is wide ranging, including, for example, obscure gastrointestinal bleeding, Crohn's disease and other inflammatory conditions, celiac disease, Behcet's disease, Meckel's diverticulum, intestinal tuberculosis, and various malignancies. Numerous informative clinical cases are presented to identify characteristic imaging findings and assist in treatment decision making. Small intestinal disease continues to represent a significant challenge. The scope and detail of this book will make it an invaluable asset for gastroenterologists and other clinicians.

The latest guidance on challenging and controversial aspects of colorectal cancer

Colorectal cancer is one of the most common forms of cancer in the US and Europe. Thousands of people are diagnosed with the disease every year and nearly half of these die as a result. As colorectal cancer is curable when detected early, a significant proportion of these deaths could be prevented by earlier diagnosis.

Much has changed since the publication of the first edition of this book in 2001: introduction of screening programs, improved diagnosis and surgery for rectal cancer, and advances in adjuvant and palliative medical therapy to name but a few.

"Challenges in Colorectal Cancer" provides the most up-to-date information on the new and emerging treatments. The second edition looks at the total patient management of this condition and is aimed at the entire medical team caring for those with colorectal cancer. It also contains the latest guidelines on epidemiology and prevention of colorectal cancer, and the application of molecular genetics.

The expanded international editor team present advice on surgical management, including new laparoscopic and endoscopic techniques and the role of the pathologist. They also review hot topics in colorectal cancer treatment, including the role of radiotherapy, options for chemotherapy and new developments in vaccines and immunotherapy.

Clostridium difficile and its toxin-producing strains are the most common causative agents of Clostridium difficile infections. It is an inflammatory bowel disease predominantly caused by prior antibiotic treatment. The use of broad-spectrum antibiotics suppresses bacterial intestinal microflora and causes overgrowth of the Clostridium difficile, and often occurs in immunocompromised, older and polymorbid patients. Following this, the authors discuss inflammatory bowel disease (including ulcerative colitis), a complex, multifactorial disease of unknown aetiology. Intestinal sulphate-reducing bacteria, especially Desuflovibrio, are often found in the intestines and faeces of people and animals with inflammatory bowel disease. Of late, the incidence of autoimmune colitis both in adults and children has been progressively increasing globally. The efficacy of conventional therapeutic measures is questionably limited due to short-term immunosuppressive effect along with possible serious side effects. As such, the authors present evidence from epidemiological studies that has demonstrated an inverse relationship between the occurrence of parasitic diseases and various autoimmune pathologies.

This practical text is indispensable to all clinicians working with dysphagia and is suitable for those involved in a range of settings and with a diversity of client groups. With its perspective on everyday working practice, "Working with Dysphagia" fills a gap in an area where practical and workable material is much sought after. This book is a useful resource for all therapists, ranging from students to specialist, as the practical assessment approach and comprehensive management strategies are supported throughout with references of recent relevant research.

This book focuses on the management of children with fecal incontinence and constipation. Despite accurate anatomic reconstruction, many children still suffer from a variety of functional bowel problems. These include not only children with congenital anatomic problems such as anorectal malformations and Hirschsprung disease, but also includes the huge population of children who suffer from constipation, with or without soiling, and a large spinal population (spina bifida) who have bowel problems.

Acute appendicitis is one of the most common surgical abdominal emergencies worldwide, with a lifetime risk of 8.6% for males and 6.7% for females. This compilation discusses how while non-operative treatment of appendicitis has been proposed as an alternative to surgery, appendicectomy remains the mainstay of treatment in most cases and techniques have shifted from open to laparoscopic methods. The current knowledge in pathogenesis, diagnosis, and clinical management of acute appendicitis is also discussed. Next, the authors present an updated review chapter of appendicitis regarding its prevalence and risk factors, particularly how the diagnosis of appendicitis is based on a history of diffuse abdominal pain, which usually starts in the central region of the abdomen and migrates to the lower right quadrant of the abdomen. The residual remnant or "stump" of the appendix after an initial appendectomy may become inflamed causing what is commonly referred to as stump appendicitis. Treatment with antibiotics may be attempted as an alternative to surgery; however, the vast majority of cases require definitive surgical excision of the remnant appendix. The authors propose that keeping this disease in the differential is important in reducing complications associated with delayed diagnosis.

For Kathleen Nicholls, life with Crohn's disease has been a constant battle against her bowels. But life has also been about David Bowie, dancing, and laughter. Go Your Crohn Way follows the highs and lows of Kathleen's experiences, and is full of useful advice for maintaining self-confidence and positivity while navigating the world of work, relationships, and those conversations. Warm and inspiring, this book demonstrates how Crohn's can be life-changing, but not just for the worse. Kathleen gives advice and tips on adapting and thriving through Crohn's, including a specially created phrasebook, which proves that so long as you know how to ask for the nearest bathroom, globe-trotting is still firmly on the agenda. Full of fun and humour, Kathleen's journey through life with Crohn's disease will leave you - like her - in stitches.

This comprehensive manual discusses the many aspects of inflammatory bowel disease (IBD), providing relevant information along with practical guidance. The reader is also directed to additional resources for extra and current information. This book comes at a time when the number of people suffering from the two major forms of IBD, ulcerative colitis (UC) and Crohn's disease (CD), is rising around the globe. Despite their huge impact on daily life and health economics, these diseases are not fully understood, and diagnosis and treatment remains a significant challenge. IBD nurses are increasingly recognised as key clinicians within the multidisciplinary team caring for people with IBD. Through experience and specialist knowledge IBD nurses provide timely support, advice, and treatment for people living with this unpredictable condition. IBD nurses are also well placed to liaise with the wider team, developing patient centred services which best fit their local health framework. The combined international expertise and accessible guidance here will equip nurses, or any clinician wanting to increase their competence in IBD management. Thereby this manual aims to contribute to the optimisation of IBD care throughout the world.

This book is written to assist those who have responsibility for the nutritional and gastrointestinal care of children with neurodisability. The emphasis throughout is on the importance of multidisciplinary care. It is concerned with the problems surrounding the nutritional management of children with neurological impairment who have difficulty swallowing and feeding. Written from a multidisciplinary perspective by a group of authors with considerable clinical and research experience in this area, it covers: ?The epidemiology of feeding disorders in children with cerebral palsy ?Nutritional assessment?Evaluation of oral-motor function?Dietetic management?Nursing issues in the nutritional care of the disabled child?Tube feeding?Gastrointestinal problems and their investigatio

A stoma is the result of an operation to remove disease such as cancer, Crohn's disease or diverticulitis - or from a bowel obstruction or injury to the digestive or urinary system. It is an artificial opening that allows faeces or urine either from the intestine or from the urinary tract to pass. There are three main types of stoma related to the digestive and urinary system - these are: colostomy, ileostomy and urostomy (Coloplast.co.uk). This book is a guide to stoma surgery and care for GI surgeons, from basic information to the latest advances in the field. Beginning with an overview of the digestive system, the next chapters explain the physiology and different types of stoma, including both permanent and temporary. The following chapters cover stoma surgery, post-surgical maintenance and possible complications. Other topics include sustenance with stoma, stoma care for different patient groups such as children or those with disabilities, the role of the stoma nurse and more. The book concludes with a section of frequently asked questions with detailed answers. Key points Comprehensive guide to stoma surgery and care for GI surgeons Covers permanent and temporary stoma and possible complications Includes FAQs with detailed answers Features clinical photographs, diagrams and tables to assist learning

Flavonoids are plant secondary metabolites with a basic polyphenolic skeleton and anticancer properties have greatly attracted the interest of scientists already for several years. This structurally diverse group of phytochemicals can be found abundantly in various edible plant products, such as fruits and vegetables, tea and cocoa, nuts, spices, grains and medicinal herbs. In the past decades, numerous experimental studies have shown antiproliferative, proapoptotic, antiinflammatory, antiangiogenic, antiinvasive and antimetastatic activities of these compounds in different cancerous systems. Because of close contacts and interactions of ingested food components with the epithelial lining of organ sites of the upper gastrointestinal tract, flavonoids can directly affect the development and progression of malignant neoplasms in the oral cavity, esophagus and stomach. This book gives a comprehensive and contemporary survey about the different anticancer actions of various natural and semisynthetic flavonoids in experimental models of oral, pharyngeal, esophageal and gastric cancers, involving the data obtained from studies of both cell lines as well as laboratorial animals. Also, the effects of flavonoids on the therapeutic responses of conventional cancer treatment modalities, i.e., different chemotherapeutic drugs and irradiation, are presented and analyzed. Moreover, the current epidemiological knowledge about the role of dietary intake of flavonoids on the risk of carcinogenesis in the upper digestive tract in populations with different dietary and lifestyle habits is described. By virtue of the high topicality of the subject but also the thoroughness of its discussion, this book could be interesting and attractive to basic scientists working in the field of plant chemicals, molecular cancer research or design and development of novel anticancer drugs; synthetic chemists in different pharmaceutical companies; health workers and nutritional counselors; medical doctors working with cancer patients; people suffering from any type of upper digestive tract tumors and their family members; and anyone who is interested in the natural tools for the fight against malignant neoplasms and whose purpose is to consciously prevent carcinogenesis within the upper gastrointestinal tract.

To all readers of this book on pancreatitis: The idea of centering a book on pancreatitis came to the authors mind after working as a general surgeon at his hospital over a period of twenty-seven years after his return from Britain, where he finished his postgraduate training and received the fellowship from the Royal College of Surgeons of Edinburgh. This book covers topics of pancreatitis including pathology, clinical presentation, investigations and treatment; it is recommended for resident surgeons and will help them to attain knowledge on pancreatitis. The author would like to thank the staff of the HBP unit at Queen Elizabeth Hospital at Birmingham, particularly Professor J. Buckle and Mr. D. Mirza, who gave the author the chance to practice his skills when he was a visiting surgeon at their unit.

Cystic tumours of the pancreas today are diagnosed more frequently in clinical practice, mainly due to an increased use of the modern advanced imaging modalities. Bland cysts of the pancreas most often develop after chronic or acute inflammation of the pancreas. However, the current knowledge concerning the development of cystic neoplasias of the pancreas is still rudimentary. Histopathologically, 90% of pancreatic cystic neoplasias are represented by four types: serous microcystic (SCN), mucinous cystic (MCN), intraductal papillary mucinous (IPMN) and solid pseudopapillary (SPN) neoplasias. Surgical treatment of these lesions can be highly challenging and occasionally demands complex surgical approaches that should be put in the hands of skilled pancreatic surgeons in experienced high-volume centres. While some of the described cystic tumours are harmless, such as SCNs of the pancreas, others such as IPMN and MCN harbour relevant malignant potential. The differential diagnosis of these lesions is critical for the patient- but often difficult. In addition, surgical treatment, even in the hands of skilled surgeons in centres of pancreatic surgery, can be complicated and can result in relevant morbidity and mortality. Therefore, it is of great importance for all doctors treating and advising patients with cystic tumours of the pancreas, i.e. surgeons, gastroenterologists, radiologists and pathologists as well as for the general practitioner, to have funded knowledge in regard to epidemiology, pathology, diagnostics and prognosis of the various pancreatic lesions, regardless of the necessity for surgical treatment. Together with recognised specialists in this field from Europe, the United States, and Japan, the authors offer a broad and detailed overview over diagnosis and the current treatment strategies for patients with cystic tumours of the pancreas.

Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and< Disease provides an overview of the basic principles of free radical formation. The text delves into free radical formation in molecular biology and its effect on subcellular damage, as well as the role of antioxidant reserves as a protective mechanism. Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

A practical, portable handbook, newly updated with nearly 100 color images and figures, The Little GI Book: An Easily Digestible Guide to Understanding Gastroenterology, Second Edition is an invaluable resource for anyone new to the world of gastroenterology and hepatology. Featuring new information on the latest advancements in gastroenterology and hepatology and written in a friendly, conversational style, The Little GI Book will help readers learn the core concepts of digestive health and disease and absorb important information without a hiccup. Author Dr. Douglas G. Adler provides a comprehensive, soup-to-nuts guide to gastrointestinal anatomy, physiology, disease states, and treatment. With new color images throughout, The Little GI Book guides the reader through the entire gastrointestinal tract, starting at the top with the esophagus, ending at the bottom with the colon and rectum, and covering everything in between: the stomach, small intestine, liver, pancreas, bile ducts, and gallbladder. The Little GI Book is an indispensable pocket guide for residents, students, nurse practitioners, office staff, industry sales force, and anyone who works in the GI industry but isn't a gastroenterologist.

Perfect for residents, generalists, medical students, nurses, and other healthcare professionals who need a practical, working knowledge of gastroenterology, Netter's Gastroenterology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This superb visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition. Up-to-date coverage of the full range of digestive diseases-including gastroenterology, hepatology, and nutrition- keeps you current with the latest information in the field. Offers a quick and memorable summary of nearly 200 of the most commonly encountered clinical conditions, from classic to contemporary. Concise text is presented in a templated format for fast, easy access to information. Features over 300 Netter and Netter-style images that highlight key aspects of patient presentation, pathophysiology, and relevant anatomy to provide a rich visual understanding of the most important concepts. Includes access to 25 printable patient education brochures in the enhanced eBook version. Provides complete guidance on all major GI diseases and conditions through sections on normal structure and function, the clinical picture, diagnosis, treatment and management, course and progress, and prevention and control. Offers dependable clinical advice from Drs. Martin H. Floch, Neil R. Floch, Joseph K. Lim, C. S. Pitchumoni, Raul J. Rosenthal, and James S. Scolapio, as well as many world-renowned chapter contributors. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

The field of gastrointestinal biology has been transformed by an explosion of knowledge for gastrointestinal motility, absorption, and secretion. The chapters in this book summarise the methods of molecular biology and the cell biology of gut enzymes, secreting cells and cells that respond to these enzymes. This book is a valuable reference for students, researchers and faculties of gastrointestinal motility, absorption and secretion. No other single source covers this field so comprehensively. It contains a considerable amount of detail on subjects such as gut hormones, gut malabsorption, alcohol toxicity on the stomach and methods used in physiologic study of the digestive tract. Disease conditions are discussed only to the extent that they illustrate physiologic mechanisms. It is difficult for such a comprehensive work to remain up to date for very long, considering how rapidly our knowledge of life sciences expands. This book, a comprehensive treatise on the causes, diagnosis, and management of gastrointestinal-motility disorders, consists of eighteen chapters with extensive references contained in slightly fewer than 300 pages. It achieves its goal through generally lucid writing and the overlap of information from chapter to chapter commonly observed in multi-authored works. Therefore, the reader is best advised to go through this book in a relaxed manner; this will allow them to finish it in a relatively short amount of time and appreciate the field of gastrointestinal motility, particularly current practices and research methods for solving its many riddles. All the chapters are clearly written, but the target audience seems to vary from medical students to practicing gastroenterologists. Despite these drawbacks, gastroenterologists, surgeons, and basic scientists wishing to bring their general knowledge of clinical motility disorders up to date will find this book useful.

Short bowel syndrome (SBS) is a pathologic condition which is characterised by reduced intestinal length and diminished intestinal absorptive capacity mainly due to extensive surgical resection, congenital defect, or pathological process affecting the small bowel. In recent decades, a better understanding of the underlying pathophysiology, new and modified surgical techniques and improvements in enteral and parenteral nutritional support improved the results of therapy of patients with SBS. This book provides research on the etiology, symptoms, surgical options and outcomes, and complications of SBS.

Nurses must deliver up-to-date, clinically effective, evidence-based care across a range of settings and develop nursing services to meet changing demands. The thoroughly revised and restructured Oxford Handbook of Gastrointestinal Nursing 2nd edition is tailored to provide the essential knowledge nurses need; at their fingertips when they need it. This handbook will guide the reader through the care of patients with a wide range of conditions of the gastrointestinal tract. Each chapter is written in a consistent structure for ease-of-use, including symptoms, causes, investigations, and treatments. Key information is provided clearly and succinctly with tables and bullet points. Chapters cover everything from anatomy to the appropriate treatment or nursing care. It now includes new conditions including colorectal cancer, anal warts, cleft lip, and volvulus, as well as the enhanced recovery after surgery pathway. Providing key summaries of common problems and essential issues, it will provide both an invaluable reference for gastrointestinal nurses, as well as a precise, targeted guide for nurses from other specialties caring for patients with GI problems.

This book provides a comprehensive overview of the epidemiology, clinical features, radiology, classification, molecular genetics, diagnosis and treatment of gastrointestinal stromal tumors in both adults and children. Various chapters of the book summarise all the important research findings and provide an updated text for all those involved in the research and clinical management of this tumor. This book is written by experts in the field from all over the world who have considerable research, clinical interest and experience in the management of this tumor. The book is a concise review of the relevant basic and clinical research on gastrointestinal stromal tumors, and provides a summary of their current classification, diagnosis and treatment strategies in both adults and children. It intends to provide a deep insight into the current knowledge on the subject and summarises all the important relevant data. It contains numerous radiologic and pathologic images, research illustrations and data that is valuable in the overall understanding of all aspects of this important tumor. This book is intended for researchers, students, paramedical staff, patients and doctors involved in the management of patients with this tumor, including gastrointestinal physicians, pediatricians, oncologists, surgeons, radiologists and pathologists. By reading this book, patients gain insight into the management of their own tumors, students find a platform on which they can build their research projects, and nurses and doctors maintain an overall understanding of the subject.