Reduce IBS symptoms with a 4-week meal plan and simple, delicious recipes! The Low-FODMAP IBS Solution Plan and Cookbook is your guide to successfully navigating the low-FODMAP diet and reducing IBS symptoms, including a 4-week meal plan and more than 100 low-FODMAP, gluten-free recipes that can be easily prepared in less than 30 minutes. If you are one of the 45 million Americans suffering from Irritable Bowel Syndrome (IBS), eating food may be the start of a vicious cycle. The Low-FODMAP IBS Solution Plan and Cookbook will provide everything you need to stop this cycle and heal your gut, using the medically proven low-FODMAP diet. Reduce symptoms of IBS and other digestive conditions with an easy-to-understand introduction to the low-FODMAP diet, a 4-week meal plan to guide you through the first phases, and more than 100 delicious low-FODMAP, gluten-free recipes that can be easily prepared in less than 30 minutes. You will receive sound, results-based advice from internationally recognized physician, surgeon and researcher Dr. Rachel Pauls, who uses the low-FODMAP diet to successfully treat her own IBS symptoms. Inside, you'll find guidance and straightforward low-FODMAP recipes that put you back in control, plus numerous vegan and vegetarian options. Enjoy mealtime once again with recipes such as: Lemon Blueberry Mug Muffins Make-Ahead Breakfast Burritos Flat-Tummy Chicken Corn Chowder Summertime Salad with Toasted Pecans Lemon Chicken with Rotini and Vegetables Tangy Turkey Sloppy Joes Peanut Pad Thai Hummus Pizza with Greek Salad Banana Chocolate Chip Oat Bars Chewy Brownie Cookies with Walnuts Scrumptious Pumpkin Pie Energy Bites Make this book the start of a healthier and happier lifestyle and a healthier and happier you!

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Gastrointestinal, fourth edition, is an invaluable resource for gastrointestinal radiologists, general radiologists, and trainees-anyone who requires an easily accessible, highly visual reference on today's GI imaging. Drs. Siva P. Raman, Atif Zaheer, and their team of highly regarded experts provide up-to-date information on recent advances in technology and the understanding of GI diseases and disorders to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice. Serves as a one-stop resource for key concepts and information on gastrointestinal imaging, including a wealth of new material and content updates throughout Features more than 2,900 illustrations (multiplanar CT, sonography, MR, and PET/CT; clinical photos; radiologic images; histologic images; H&E stains; and full-color illustrations) as well as an additional 3K digital-only images and new video clips Features updates from cover to cover including new information on MRI imaging of rectal cancer, iron quantification, and MRI protocols; new cases and images, and new staging details and diagrams Contains new chapters on treatment response criteria for systemic conditions (RECIST, irRECIST, etc.), dual energy CT for pancreas, vascular abnormalities, MR elastography of the liver, pretransplant liver evaluation, and more Covers all aspects of GI imaging, including pathophysiology, imaging findings, and disease management options such as the radiologist's role in evaluating patients for bariatric surgery, antireflux procedures, esophageal and bowel resections, and more Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers' understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special "clinical correlates" sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.

This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

We live in an era of personalized medicine and the knowledge about pathophysiology of diffuse gastric cancer has had many advances. Thus, the role of this work is to clarify what is new from diagnosis to treatment of this disease in order to treat patients in the most tailored manner as possible. Almost all phase III trials in gastric cancer have been performed without taking in consideration histologic subtypes, i.e. they have disregarded the differences between diffuse gastric cancer and general gastric cancer. However, the clinical practice reveals that diffuse gastric cancer is a completely distinct disease, with an aggressive course and generally worse prognosis. The loss of cohesion between tumor cells due to the loss of E-cadherin synthesis is the critical point on the oncogenesis of diffuse gastric cancer and is at the root of its marked heredity. This book intends to give special attention to Diffuse Gastric Cancer as a particular oncological entity, differentiating it from general gastric cancer, exploring and discussing all its peculiarities, and addressing the basic aspects (pathology and genetics) along with the most recent therapeutic alternatives for this condition.

This book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use of radiological and endoscopic studies that are performed to make a diagnosis, and the role of the pathological examination. The book also includes detailed information on the medical treatment of the disease, written by some of the most expert gastroenterologists in the field, while also paying considerable attention to the latest medical treatments and to expected future developments. The book describes various surgical techniques for ulcerative colitis in detail, providing readers with concrete guidelines on which is the most appropriate operation to perform in any given case. It also presents extensive information on the most important operation, the formation of the IPAA (ileal pouch-anal anastomosis), together with helpful tips and tricks. A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastroenterologists, researchers and students alike.

The Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition outlines nursing care before, during, and after endoscopic procedures. Written with both the novice and experienced nurse in mind, the Third Edition of The Johns Hopkins Manual for GI Endoscopic Nurses provides practical tips for all basic and advanced endoscopic procedures. Dr. Anthony Kalloo is joined by Mouen Khashab and Toshunia Robinson on the Third Edition of this popular manual. The Johns Hopkins Manual for GI Endoscopic Nurses features up-to-date guides to new endoscopic procedures and techniques, such as fiducial placement, balloon-assisted enteroscopy, Barrett's ablation, Spyglass cholangioscopy, and pancreatoscopy. Additional chapters cover sedation, antibiotic prophylaxis, disinfection, and the management of patients on anticoagulation medication. General guidelines for moderate sedation, equipment disinfection, and sterilization are also discussed, as well as special considerations for patients with specific medical conditions who are undergoing endoscopy. Endoscopy nurses, gastroenterology fellows, and gastroenterology practitioners alike can use The Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition's endoscopic preparation regimens to facilitate the correct instruction of patients, reducing the likelihood of unsuccessful procedures. This spiral-bound resource also includes the definitions and indications for both common and advanced endoscopic procedures along with listings of necessary equipment. The Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition is easy to read and comprehend, with photographs and illustrations replacing cumbersome long descriptions, making this the ideal reference for a nurse on the go.

This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.

This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.

This volume provides a comprehensive and up-to-date theoretical review and practical guide on pediatric gastrointestinal motility and functional disorders. The latest edition includes extensively revised and new chapters to reflect the rapidly growing field of pediatric neurogastroenterology. New topics covered include neurobiology of pain in children, functional oropharyngoesophageal assessment, dysautonomia, and psychotropic drugs. The text also features instructive illustrations, photographs, and tables. Written by world-renown experts in the field, Pediatric Neurogastroenterology: Gastrointestinal Motility and Functional Disorders in Children, Second Edition is a valuable resource for pediatric gastroenterologists, adult gastroenterologists, pediatricians, and all professionals involved in the treatment and management of children with such disorders.

This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett's esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett's esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer's Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.

Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

Surgery has traditionally been the standard of care for the treatment of neoplastic lesions in the gastrointestinal tract. With advances in endoscopic resection techniques, there has been a paradigm shift in how to approach many of these precancerous and early cancerous lesions. Potential advantages of endoscopic resection include its minimally invasiveness which often translates into quicker patient recovery. In recent years, there have been major strides in safety and efficacy of minimally invasive endoscopic approaches with ongoing advances in therapeutic endoscopy. Advanced Techniques for Endoscopic Resection in the GI Tract by Drs. Peter V. Draganov, Takuji Gotoda, and Dennis J. Yang provides an in-depth analysis of the current state of advanced endoscopic techniques for the evaluation and resection in the gastrointestinal tract. Each chapter in the book addresses specific topics such as: - Endoscopic evaluation of lesions - Technical aspects of the procedure - Management of adverse events - Post-procedural care and follow-up Advanced Techniques for Endoscopic Resection in the GI Tract provides a comprehensive review of all the different aspects of advanced endoscopic resection in the gastrointestinal tract which makes it ideal for interventional GI endoscopists and general gastroenterologists, as well as surgeons.

Nearly 30 years ago, a number of scientists working on the Enteric Nervous System (ENS) gathered at Flinders University, in Adelaide, Australia to discuss the advances and future of their research. It was a friendly and stimulating meeting, attended by most of the major players, in what was to become the discipline of 'Neurogastroenterology'. In 2014, the main Australasian Neuroscience Society meeting was held in Adelaide, Australia, providing the perfect opportunity to recreate a follow-up ENS meeting. As such, the 'ENS II 2014 meeting' aimed to identify how far the field of enteric neuroscience had developed, where the future was heading, and what technological advances had been made to address current and future unresolved questions. 30 speakers from around the world were invited to give talks and revisit the original expectations, the advances made since, and the future directions of ENS research. These discussions included three generations of investigators from 7 different countries. This publication represents the majority of proceedings from the 'The Enteric Nervous System II 2014' conference, which was held on February 1st - 2nd 2014 at the National Wine Centre of Australia, Adelaide. This meeting was an Official satellite meeting of the 34th Annual Meeting of Australasian Neuroscience Society, which was also held in Adelaide. The 20 contributions contained within this submission are from international researchers in the field of the ENS, who reviewed the advances made since the first meeting in the early 1980s and summarizes the present and future perspectives of neuro-gastroenterology. Some colleagues could not attend but did send greetings and their messages are included in these proceedings.

The brain-gut connection has been increasingly implicated in biopsychosocial well-being. While there are numerous factors that directly and indirectly impact on how the gut and the brain interact, there is a growing awareness that gastrointestinal conditions need to be viewed and treated as part of a multidisciplinary approach. Psychogastroenterology for Adults: A Handbook for Mental Health Professionals is the first book to provide mental health professionals with an evidence-based, practical guide for working with patients living with gastrointestinal conditions. Timely and accessibly written, this book provides a unique, comprehensive introduction to psychogastroenterology, offering a step-by-step guide to evidence-based psychological treatment protocols. Broad in scope and expertise, the book is divided into four parts. It opens with an overview of the field, moving on to outline psychological concerns and conditions in gastroenterological (GI) cohorts. Further, it covers various approaches to psychogastroenterology, including psychopharmacological and eHealth practices. In closing, the book looks to the future, providing guidance on supervision in psychogastroenterology, and exploring challenges in the field. Written by experts in the field, this book will be an indispensable resource for those who wish to enhance their knowledge and practice of psychogastroenterology in the mental health profession, including psychologists, psychiatrists, psychosomatic medicine specialists, nurses and social workers.

Gastroenteritis viruses are a major cause of morbidity and mortality in humans. Many hundreds of thousands of children die annually from rotavirus diarrhoea in the developing world, and although in industrialized countries rotavieus infection is rarely fatal, the economic burden of the disease is substantial. Human caliciviruses have emerged as a significant cause of viral gastroenteritis globally. This book contains presentations and discussions by internationally recognized experts on virus structure, replication, pathogenesis, immune response and correlates of protection, molecular-epidemiological surveillance, advances in treatment, and efforts to develop vaccines, particularly against rotavirus disease. The spectrum of viruses covered comprises rotaviruses, human caliciviruses, astroviruses, coronaviruses and viruses causing gut disease in the immunocompromized host. The book not only conveys facts but also gives ample room to lively discussions on many issues at the forefront of research and development.

Endoscopic access to the small intestine has long presented a challenge to physicians. This book describes the principles, insertion technique, and clinical applications of double-balloon endoscopy, which will become the gold standard of enteroscopy and which may well eliminate the need for intraoperative enteroscopy in many patients. Leading the way to a new approach, this book provides an invaluable source of reference for all practitioners working in the field.

Advanced Imaging of the Abdomen is invaluable to the practising radiologist, and the more senior radiology resident and fellow, who is looking for a background reference source when discussing a suggested imaging approach with the referring physician. The book includes extensive lists, tables, line drawings and illustrations - ultrasonography, computed tomography, magnetic resonance images, scintigraphy. It bridges the interface between the referring clinician and radiologist when faced with a patient suspected of having a complex or more unusual abdominal condition.

• Contributors are internationally known experts • Richly illustrated • Focuses on the differences of diagnostic methods between Japan and other countries by using endoscopic and pathologic pictures • For the first time, the Japanese progress in the field is published in English and made accessible to researchers worldwide

Atlas of Virtual Colonoscopy thoroughly revises and updates Abraham Dachman's bestselling first edition. Joined in this edition by co-editor Andrea Laghi, Dr. Dachman has expanded the focus of the text to cover fundamental topics of this rapidly evolving technology, including the history of virtual colonoscopy, a review of clinical trial data from throughout the world, and a presentation of clinical background information. Also included are chapters covering patient preparation and tagging, performing and reporting virtual colonoscopy, viewing methods, MR colonography, and computer aided detection. The second part of the text presents an atlas of high-resolution images with detailed explanations of teaching points, covering normal anatomy; sessile, pedunculated, diminutive and flat lesions; masses; stool and diverticula; and common pitfalls. Atlas of Virtual Colonoscopy is a valuable resource for all radiologists and gastroenterologists interested in learning the fundamentals of this exciting technique.

This is the first book compiling current research on the gut-bone signaling axis and its implications in the pathophysiology of GI and bone diseases. Rather than focusing on a single mechanism, this book provides the reader with a broad view on gut-bone signaling and the most up-to-date information in this rapidly growing area. The volume is also unique in that it looks at what is known about GI diseases affecting bone and then examines the role of the microbiome and its modulation by pre and probiotics to treat bone disease, placing this topic within the context of gut-bone signaling pathways. Understanding the Gut-Bone Signaling Axis will thus provide an understanding of how various therapies could be applied to this area.

This book concerns the mathematical modeling and computer simulation of the human stomach. It follows the four modern P's (prevention, prediction, personalization, and precision in medicine) approach in addressing the highly heterogeneous nature of processes underlying gastric motility disorders manifested as gastroparesis, functional dyspepsia, myenteric enteropathy etc. The book comprehensively guides readers through the fundamental theoretical concepts to complex physiological models of the organ. This requires a deep and thorough understanding of driving pathophysiological mechanisms as well as the collaborative effort of specialists working in fundamental and biological science. Such a multidisciplinary partnership is vital because it upholds gnostic capabilities and provides the exchange of thoughts and ideas thus offering broad perspectives into the evolution and management of diseases. The book is a valuable resource for applied mathematicians, computational biologists, bioengineers, physicians, physiologists and researchers working in various fields of biomedicine.