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Books > Medicine > Clinical & internal medicine > Gastroenterology

Intestinal Failure - Diagnosis, Management and Transplantation (Hardcover): A Langnas Intestinal Failure - Diagnosis, Management and Transplantation (Hardcover)
A Langnas
R4,195 Discovery Miles 41 950 Ships in 12 - 17 working days

Intestinal failure is a challenging, emerging field that has been the subject of much research and debate in recent years and has only recently become widely accepted as a distinct clinical syndrome.
This comprehensive book provides an in-depth review of scientific theory and clinical practice relating to intestinal failure with specific emphasis on assessment and management as part of a multidisciplinary team. Compiled by an internationally recognised editorial team, the book provides a practical how-to guide to the management of adult and pediatric patients with intestinal failure, focusing on quality-of-life issues that are at the heart of patient care.
* World experts from centers of excellence share their clinical experience and expertise, offering the first ever authoritative resource on intestinal failure
* All aspects of patient management are covered, from diagnosis and medical and surgical management (including transplantation) to nutritional consideration and psychosocial aspects of care
* Numerous illustrations, flow diagrams and summary boxes complement the text and emphasize important concepts, providing an accessible approach to this complex field
This landmark book is essential reading for any gastroenterologists, surgeons, transplant teams or clinical nutritionists involved in the care of patients with intestinal failure.

Digestive Intelligence - A Holistic View of Your Second Brain (Paperback): Irina Matveikova Digestive Intelligence - A Holistic View of Your Second Brain (Paperback)
Irina Matveikova 1
R311 R211 Discovery Miles 2 110 Save R100 (32%) Ships in 12 - 17 working days

Digestive Intelligence tells the fascinating story of how our digestive systems are the centre of our bodies' second brain and how we think and live our emotions via our stomachs. Not surprising when you consider there is something equivalent to the size of a village football pitch hiding inside our bellies - that's the incredible magnitude of our digestive systems. Dr Matveikova answers the obvious questions: "How?" and "Why can this be so?" by explaining, in straight forward layman's language, that the digestive system contains more than one million neurones, identical to those in the brain and is responsible for producing 90% of the body's hormone, serotonin, the all-important hormone which makes us feel happy and full of wellbeing. It follows that, if our stomach is "out of sorts" we feel irritable and lacking in energy; and those feelings block our intellectual productivity, disorientate us and completely change our thought patterns and physical processes.

Clostridioides difficile - Infections, Risk Factors, Prevention and Treatment (Paperback, 1st ed. 2021): Henning Sommermeyer,... Clostridioides difficile - Infections, Risk Factors, Prevention and Treatment (Paperback, 1st ed. 2021)
Henning Sommermeyer, Jacek Piatek
R2,589 Discovery Miles 25 890 Ships in 10 - 15 working days

The book provides a comprehensive overview of the current knowledge about Clostridioides (C.) difficile (formerly known as Clostridium difficile) and Clostridioides difficile infections (CDI). The diseases caused by C. difficile range from mild diarrhea to fulminant and in some cases fatal colitis. Historically, CDI was considered mainly as a hospital-acquired problem. Today, a significant portion of CDI is community acquired. Triggered by the introduction of new antibiotics, hypervirulent and multi-drug resistant strains of C. difficile (e.g., C. difficile ribotype R027) have emerged and spread across the globe. The volume covers the microbiology, pathophysiology, epidemiology, risk factors for CDI, diagnosis, clinical pictures, treatment and prophylaxis. It includes an extensive reference list that allows an easy navigation through the original research publications. Clostridioides difficile helps the reader gain a better understanding of C. difficile, the challenges that may arise and the available treatment options. Given its broad coverage and features, it will appeal to a wide readership, from gastroenterologists through general physicians, nurses, and other healthcare providers, to students.

Hepatocellular Carcinoma - Translational Precision Medicine Approaches (Hardcover, 1st ed. 2019): Yujin Hoshida Hepatocellular Carcinoma - Translational Precision Medicine Approaches (Hardcover, 1st ed. 2019)
Yujin Hoshida
R3,973 Discovery Miles 39 730 Ships in 10 - 15 working days

This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Surgery in the Multimodal Management of Gastric Cancer (Hardcover, 2012): Giovanni De Manzoni, Franco Roviello, Walter Siquini Surgery in the Multimodal Management of Gastric Cancer (Hardcover, 2012)
Giovanni De Manzoni, Franco Roviello, Walter Siquini
R4,420 Discovery Miles 44 200 Ships in 10 - 15 working days

Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.

The A.S.P.E.N. Pediatric Nutrition Support Core Curriculum (Paperback, 2nd Revised edition): Mark R Corkins The A.S.P.E.N. Pediatric Nutrition Support Core Curriculum (Paperback, 2nd Revised edition)
Mark R Corkins
R4,827 Discovery Miles 48 270 Ships in 12 - 17 working days

Written with an interdisciplinary, evidence-based approach, the second edition of The A.S.P.E.N. Pediatric Nutrition Support Core Curriculum provides a firm foundation of nutrition support knowledge for health professionals caring for infants and children. In the preface, Dr Corkins noted that this text was "designed to start with the basic nutrition physiology before progressing through the principles for nutrition in specific disease states. It ends with the 'nuts and bolts' for daily care." This core textbook features 37 chapters, each with learning objectives and 'Test Your Knowledge' review questions. The chapters are organized into four main sections: Introductory and Basic Physiology: covers macronutrients, micronutrients, fluids and electrolytes, the mechanics of intake, and digestion and absorption. Age-Specific Nutrition for Growth and Development: provides considerations for human milk, infant formulas, complementary feeding, enteral formulas, and changes that occur with development. Obesity, lipid disorders and sports nutrition are also given a thorough review. Disease States and Nutrition: delves into acute and chronic diseases of infants and children from birth, including topics as diverse as inborn errors of metabolism, eating disorders, food allergies, trauma and burns, and oncology. Nutrition Care of the Pediatric Patient: a practical reference for nutrition assessment, route of feeding, ethical issues, and monitoring and evaluating patient responses to feeding.

Cancer Screening in Inflammatory Bowel Disease - A Guide to Risk Management and Techniques (Hardcover, 1st ed. 2019): Joseph D.... Cancer Screening in Inflammatory Bowel Disease - A Guide to Risk Management and Techniques (Hardcover, 1st ed. 2019)
Joseph D. Feuerstein, Adam S Cheifetz
R1,533 Discovery Miles 15 330 Ships in 10 - 15 working days

This book provides a concise, yet comprehensive overview of cancer risks in patients with inflammatory bowel disease (IBD), as well as the screening modalities used to reduce these risks. Each chapter presents a major malignancy that patients with IBD are at risk from, stemming from the disease itself or from the medications used to treat the disease. Malignancies covered include colorectal cancer, skin cancer, lymphoma, and other cancers. Cancer risk and screening with current and emerging drug therapies are also discussed. Written by experts in the field, Cancer Screening in Inflammatory Bowel Disease: A Guide to Risk Management and Techniques is a valuable resource for gastroenterologists, colorectal surgeons, and primary care physicians who treat and manage patients with inflammatory bowel disease.

Liver Disease - A Clinical Casebook (Paperback, 1st ed. 2019): Stanley Martin Cohen, Perica Davitkov Liver Disease - A Clinical Casebook (Paperback, 1st ed. 2019)
Stanley Martin Cohen, Perica Davitkov
R2,919 R2,555 Discovery Miles 25 550 Save R364 (12%) Ships in 12 - 17 working days

This clinical casebook provides a concise yet comprehensive state-of-the-art review of liver disease. Presented in a case-based format, each case features a scenario centered on a different variant of liver disease, with sections on case history, diagnosis/assessment, treatment, outcomes, alternative approaches, and clinical pearls. Diseases covered include drug-induced liver injury, acute hepatitis, chronic hepatitis, NAFLD, and cholangitis. Scenarios such as liver disease in pregnancy, elevated liver function tests, and liver transplants are also presented in the casebook. Written by experts in the field, Liver Disease: A Clinical Casebook is a valuable resource for clinicians and practitioners who treat patients with liver disease.

Gastroenterology & Hepatology - The Next Millennium (Paperback): G.N.J. Tytgat, G.J. Krejs Gastroenterology & Hepatology - The Next Millennium (Paperback)
G.N.J. Tytgat, G.J. Krejs
R854 R657 Discovery Miles 6 570 Save R197 (23%) Ships in 12 - 17 working days

Postgraduate education courses taught by the leading hepato-gastroenterologists in Europe, members of the EAGE, are published each year as part of this collection.

Viral Hepatitis: Acute Hepatitis (Paperback, 1st ed. 2019): Resat Ozaras, Joop E. Arends Viral Hepatitis: Acute Hepatitis (Paperback, 1st ed. 2019)
Resat Ozaras, Joop E. Arends
R1,520 Discovery Miles 15 200 Ships in 10 - 15 working days

This book presents up-to-date, practically oriented information on major topics in acute hepatitis. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. The book opens by examining the local and global epidemiology of acute hepatitis. Detailed attention is then paid to each of acute hepatitis A, acute hepatitis B, acute hepatitis C, hepatitis D co-infection, and hepatitis E. Acute Hepatitis will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Hemorrhoids (Hardcover, 2014 ed.): Hyung Kyu Yang Hemorrhoids (Hardcover, 2014 ed.)
Hyung Kyu Yang
R2,654 R2,455 Discovery Miles 24 550 Save R199 (7%) Ships in 9 - 15 working days

This book provides up-to-date knowledge on hemorrhoids for proctologists. It covers all aspects, including the history of hemorrhoids, the anatomy of the anal canal, pathophysiology, diagnosis, and treatment. Both conservative treatment approaches and surgical methods are explained with the aid of numerous high- quality illustrations and schematic drawings. Particular attention is paid to lift-up submucosal hemorrhoidectomy, developed by the author by modifying Parks' original method. Additionally, other important techniques proposed by world leaders in the field are described and illustrated. The international trend towards use of day-case hemorrhoidectomy is acknowledged by considering this approach in detail, with discussion of patient preparation, anesthesia, surgical technique, and postoperative management. The treatment of hemorrhoids in a variety of special circumstances is examined, including new trends in PPH. The closing chapter is devoted to the various forms of anesthesia for anal surgery.

Acing the IBD Questions on the GI Board Exam - The Ultimate Crunch-Time Resource (Paperback): Brennan Spiegel, Hetal Karsan Acing the IBD Questions on the GI Board Exam - The Ultimate Crunch-Time Resource (Paperback)
Brennan Spiegel, Hetal Karsan
R4,357 Discovery Miles 43 570 Ships in 12 - 17 working days

The world of inflammatory bowel disease (IBD) knowledge is vast. Within that world is a sub-set of knowledge that is especially important for everyday clinical care. And a sub-set of that is testable for the Board exam. The testable material includes time-honoured, locked-in-stone, mostly uncontroversial facts that have withstood the test of time. The answer to your study questions (and reduction of your study time!) can be found inside Acing the IBD Questions on the GI Board Exam: The Ultimate Crunch-Time Resource. Until now, there has been no single, slim, but high-yield volume that summarises the IBD you really need to know for the board exams, preparing for rounds, or just plain read. The authors have collected every pearl of wisdom, high-yield factlet, IBD ""Board buzzword"", micrograph, and classic imaging study they could muster, all while keeping Acing the IBD Questions on the GI Board Exam: The Ultimate Crunch-Time Resource a manageable size. In today's fast-paced world it is hard to keep up with the burgeoning IBD literature. Traditional textbooks usually feature long and detailed discussions that don't directly address board and recertification exams. On the flip side, many board review manuals provide lists and bullet points lacking sufficient background and context. Acing the IBD Questions on the GI Board Exam by Drs. Brennan Spiegel and Hetal Karsan, fills the unmet need in board review by presenting time-tested and high-yield information in a rational, useful, and contextually appropriate format. With its focus on pearl after pearl, emphasis on images, and attention to high-yield "tough stuff" vignettes you don't know the answers to (yet), Acing the IBD Questions on the GI Board Exam: The Ultimate Crunch-Time Resource will help you ace the GI and recertifying examinations, look good on clerkship rounds, simply challenge you with interesting and entertaining vignettes, and take optimal care of your IBD patients in clinical practice.

The Digestive Involvement in Systemic Autoimmune Diseases, Volume 13 (Hardcover, 2nd edition): Manuel Ramos-Casals, Munther A.... The Digestive Involvement in Systemic Autoimmune Diseases, Volume 13 (Hardcover, 2nd edition)
Manuel Ramos-Casals, Munther A. Khamashta, Pilar Brito-Zeron, Fabiola Atzeni, Joan Rod es
R4,028 Discovery Miles 40 280 Ships in 12 - 17 working days

The Digestive System in Systemic Autoimmune Diseases, Second Edition, represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. This volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico, and South Africa share their knowledge in this detailed volume. The book provides an overview of our current understanding of digestive disorders in the most common systemic autoimmune diseases.

The Gastritis Healing Book - A Comprehensive Guide to Heal Gastritis and Restore Your Stomach Health (Paperback): L G Capellan The Gastritis Healing Book - A Comprehensive Guide to Heal Gastritis and Restore Your Stomach Health (Paperback)
L G Capellan
R533 R444 Discovery Miles 4 440 Save R89 (17%) Ships in 10 - 15 working days
Liver Pathophysiology - Therapies and Antioxidants (Hardcover): Pablo Muriel Liver Pathophysiology - Therapies and Antioxidants (Hardcover)
Pablo Muriel
R3,829 Discovery Miles 38 290 Ships in 12 - 17 working days

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies.

Multidisciplinary Management of Eating Disorders (Hardcover, 1st ed. 2018): Jane Morris, Alastair McKinlay Multidisciplinary Management of Eating Disorders (Hardcover, 1st ed. 2018)
Jane Morris, Alastair McKinlay
R2,984 Discovery Miles 29 840 Ships in 10 - 15 working days

This Handbook is an indispensable guide for the multidisciplinary management of eating disorders. It discusses a broad range of issues: managing high-risk patients, the challenges of inserting feeding tubes, addressing nutritional aspects and dealing with additional disorders which might complicate matters, such as diabetes, coeliac disease and cystic fibrosis. It discusses fertility, pregnancy, and eating disorders in children and adolescents, as well as addressing the needs of families. Chapters contain key checklists and flow diagrams. Abundant pictures and conversations, coloured diagrams, charts, maps and boxes, support readers' varying learning styles and assist retention of key points. Vignettes taken from real (but strenuously anonymised) cases appeal to clinicians' preference for case-based learning. The book also functions as a practical manual of 'What to do - and what NOT to do' with practical scenarios. In the acute situation, clinicians will be able to go directly to the relevant chapter to guide the team through the 'when, where, how, why and with whom' of assessing and managing patients with eating disorders. The book is primarily aimed at postgraduate physicians managing patients with Eating disorders on Gastrointestinal, Endocrine or general medical wards, and those who seek to deepen their expertise as they sit higher professional examinations. It is of interest to both medical and psychiatric clinicians, as well as useful to nursing and multidisciplinary staff who want to develop a compassionate understanding of the true pain driving their patients' behaviours.

Hemorrhoids (Hardcover, 1st ed. 2018): Carlo Ratto, Angelo Parello, Francesco Litta Hemorrhoids (Hardcover, 1st ed. 2018)
Carlo Ratto, Angelo Parello, Francesco Litta
R8,583 Discovery Miles 85 830 Ships in 10 - 15 working days

This book offers a comprehensive guide to hemorrhoidal disease, the most frequent coloproctological affection. In addition to amply illustrated chapters covering the epidemiology and anatomic, physiologic, and pathophysiologic bases of hemorrhoids, readers will find helpful information on the classification of hemorrhoidal disease and modalities to assess it, as well as their significant impact on the choice of treatment. The work presents a complete panel of all therapies usually adopted to treat this condition and their outcomes, which are critically commented on by prominent specialists. Further, management of the disease in special conditions is also discussed. Lastly, a literature review and evaluation of the impact of different treatments on the patient's quality of life round out the volume, which is part of the Reference Work series entitled Coloproctology.

The Microbiota in Gastrointestinal Pathophysiology - Implications for Human Health, Prebiotics, Probiotics, and Dysbiosis... The Microbiota in Gastrointestinal Pathophysiology - Implications for Human Health, Prebiotics, Probiotics, and Dysbiosis (Hardcover)
Martin H. Floch, Yehuda Ringel, W Allen Walker
R4,191 Discovery Miles 41 910 Ships in 12 - 17 working days

The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research.

Bariatric Surgery Patients - A Nutritional Guide (Paperback): Betty Wedman-St. Louis Bariatric Surgery Patients - A Nutritional Guide (Paperback)
Betty Wedman-St. Louis
R2,873 Discovery Miles 28 730 Ships in 12 - 17 working days

"Approximately 65% of our population is overweight and 12% are morbidly obese. This is despite more than 25 years of attempted medical management. Clearly all current efforts have failed to control this enormous problem. Could it be that we have failed to recognize the cause of the disease and therefore have misdirected our efforts?" - Alfredo Fernandez, MD, FASMBS, Surgeon, Tampa, Florida Reducing obesity through bariatric surgery provides a sustainable weight loss regimen, because it restricts the size of the stomach and limits food intake. However, the surgery limits the amount of nutrients absorbed by the stomach and small intestine. This book provides a comprehensive, practical guide on pre- and post-nutrition considerations in bariatric patients. It describes surgeries including gastric bypass, lap band, and sleeve; nutrition protocols for surgery patients; pregnancy considerations- pre- and post-surgery; food consumption post-surgery; advancing healthy food intake after surgery; minimizing negative side effects; and recommendations to maintain healthy diet. This nutritional guide provides health care practitioners descriptions and answers to the many questions bariatric surgery patients need to know and ask in support group meetings and individual counseling sessions. The first chapter focuses on Selling Obesity and Food as a Cheap and Legal Drug, outlining how food advertising, portion size increases, and food frauds have contributed to the obesity crisis. New research into gut hormones, microbiome influence on obesity, firmicutes, and histamine are included, as well as pregnancy after bariatric surgery and lifestyle changes-eating, sleep, hydration, stress management-needed for success after surgery. Many health care practitioners will use the Post Op Discharge Diet stages of progression to explain how the patient needs to prepare for their liquid diet and overcome numerous issues like dumping syndrome, hypoglycemia, and alcohol and caffeine consumption. Diet plans for Ketogenic, Mediterranean DASH, Glycemic, and Low FODMAP are included within this book.

Barrett's Esophagus - Emerging Evidence for Improved Clinical Practice (Paperback): Douglas Pleskow, Tolga Erim Barrett's Esophagus - Emerging Evidence for Improved Clinical Practice (Paperback)
Douglas Pleskow, Tolga Erim
R2,578 Discovery Miles 25 780 Ships in 12 - 17 working days

Barrett's Esophagus: Emerging Evidence for Improved Clinical Practice is a comprehensive reference on the treatment and new imaging modalities of Barrett's Esophagus for researchers, clinicians, and scholars. Each chapter is composed from the perspective of investigators who summarize the data as well as the reasoning behind why those studies were conceived. In addition, the future directions of research are discussed within each chapter, providing insights from the investigators. Research questions are described, and cutting-edge applications are explained. Each chapter contains clinical scenarios to highlight the directions in which the research is, and should be, heading.

Variceal Bleeding in Liver Cirrhosis (Hardcover, 1st ed. 2021): Xiaozhong Guo, Xingshun Qi Variceal Bleeding in Liver Cirrhosis (Hardcover, 1st ed. 2021)
Xiaozhong Guo, Xingshun Qi
R2,897 Discovery Miles 28 970 Ships in 10 - 15 working days

This book discusses the management of variceal bleeding in liver cirrhosis, covering a wide range of topics, including epidemiology, mechanism, diagnosis and monitoring, prophylaxis, treatment, and prognostic assessment. It also presents the latest research in the field, such as non-invasive approaches, self-expanding metal stents, hemostatic powder, and early TIPS. The book is a valuable resource for physicians wanting to establish standard treatment strategies, researchers launching innovative clinical and experimental studies, and also for patients and their relatives wishing to gain a better understanding of this disease.

OESO - Barrett's Esophagus (Paperback): L. Lundell, Daniel Couturier, Carmelo Scarpignato OESO - Barrett's Esophagus (Paperback)
L. Lundell, Daniel Couturier, Carmelo Scarpignato
R6,401 R4,490 Discovery Miles 44 900 Save R1,911 (30%) Ships in 12 - 17 working days

This 6th volume of OESO has the advantage to address a topic which is at the forefront of concern for all those involved with disease of the upper digestive tract: an entity inserted in the epidemiological sequence of GERD, a benign affection among the most widespread in the world, Barrett's esophagus, has become today a problem of Public Health. Its recognised propensity to degenerate has, in fact, made it one of the benign lesions of the upper digestive tract which legitimately arouses the convergent interest of clinicians, as well as those devoted to fundamental research. Large scale epidemiological studies, the development of even sharper means for early detection of the precursory signs of its degeneration, the extreme diversity of the treatments available today, all lend new perspectives to the different centres of interest of this book.

Uremic Toxins and Organ Failure (Hardcover, 1st ed. 2020): Hideyuki Saito, Takaaki Abe Uremic Toxins and Organ Failure (Hardcover, 1st ed. 2020)
Hideyuki Saito, Takaaki Abe
R2,893 Discovery Miles 28 930 Ships in 10 - 15 working days

This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.

Hepatocellular Carcinoma - Diagnosis and Treatment (Hardcover, 3rd ed. 2016): Brian I. Carr Hepatocellular Carcinoma - Diagnosis and Treatment (Hardcover, 3rd ed. 2016)
Brian I. Carr
R4,784 Discovery Miles 47 840 Ships in 10 - 15 working days

* Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today's hepatologists and medical and surgical oncologists. "This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology "...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease

Cancer - Bowel Screening A Simple Guide About How It Works To Help You Decide (Paperback): Anthea Peries Cancer - Bowel Screening A Simple Guide About How It Works To Help You Decide (Paperback)
Anthea Peries
R289 Discovery Miles 2 890 Ships in 10 - 15 working days
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