Do you suffer from bloating, a chronic cough or sore throat? Relieve and heal your acid reflux symptoms with this tried-and-tested 28-day dietary programme!

In The Acid Watcher Diet, Dr Jonathan Aviv, a leading authority on the diagnosis and treatment of acid reflux disease, helps readers identify those often misunderstood symptoms while providing a proven solution for reducing whole-body acid damage quickly and easily.

His 28-day programme is part of a two-phase eating plan, with a healthy balance of both macronutrients (proteins, carbs and fats) and micronutrients (vitamins, minerals and antioxidants), that works to immediately neutralize acid and relieve the inflammation at the root of acid reflux. Dr Aviv guides readers through healthy dietary choices with targeted recipes, helping them balance their bodies and minds for optimal health and break acid-generating habits for good.

"BetaSys" uses the example of regulated exocytosis in pancreatic -cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.

With 2300 radiological images dispersed throughout the text, this source provides an expansive armamentarium of case studies and examples showcasing both common and uncommon liver pathologies. Serving as an unparalleled how-to source for the investigation of liver disease by MRI, this guide demonstrates key MRI techniques currently utilized in clinical practice, as well as explains the choice of acquisition sequences, specific parameters, and the use of contrast media for each application.

This book contains the proceedings of Falk Symposium 167 entitled 'Liver under Constant Attack - From Fat to Viruses', which was held in Mainz, Germany, on 20-21 September 2008. It merges up-to-date viral liver immunology with relevant topics in clinical practice. Sections cover viral hepatitis, immunosuppressive approaches in liver patients, malignant liver diseases, inflammatory liver diseases and complications of liver cirrhosis. Interdisciplinary discussion of new concepts in the treatment of liver diseases makes this book valuable for scientists and clinicians alike.

Despite the expected decline in the mid-1970s in the use of computed tomography (CT) following the excitement of magnetic resonance imaging (MRI), CT has confounded its detractors and remains the imaging modality of choice, particularly for the chest and abdomen. Spiral/helical CT with the development of 64-multislice variant has revolutionized diagnostic imaging: image acquistion of large body volumes are obtained in short times during a single-breath hold. Scanning protocols without contrast enhancement are not a challenge; however, with intravenous contrast agents, critical choices are made and bad choices inevitably produce bad scans. This handy guide provides the reader with a simple introduction to the essential ideas involved and a practical guide to the implementation of rational scanning protocols for multislice spiral instruments. Written by Peter Dawson, a well-respected figure in computed tomography and radiology, and a world expert on contrast agents, Scanning Protocols for Multislice Helical Computed Tomography is an essential guide for all those working with CT, as well as those in training.

A detailed compilation of the latest research and recommendations for the diagnosis and assessment of esophageal disorders, this reference delves into a wide range of applications and technologies currently utilized in the field including radiology, endoscopy, endoscopic ultrasonography, manometry, ambulatory manometry, pH testing, catheter-free pH testing, bilitec monitoring, and impedance plethysmography.

Dr. Alan Buchman, Consulting Editor, selected world renown experts on celiac disease, Dr. Green and Dr. Lebwohl, to update the topic for gastroenterology readers. They have secured expert authors from top institutions to contribute articles with high clinical utility on the diagnosis, treatment, and management of celiac disease. These clinical reviews are devoted to the following topics: Clinical features and diagnosis of celiac disease; The gluten-free diet; Histopathology of celiac disease; Epidemiology and risk factors for celiac disease; Enteroscopy and capsule endoscopy in celiac disease; Measuring symptoms and other outcomes in celiac disease; Celiac disease in Asia; The microbiome and celiac disease; Follow-up of celiac disease; Refractory celiac disease; Non-dietary therapies for celiac disease; and Non-Celiac gluten or wheat sensitivity. Readers will come away with the most current clinical information they need to inform clinical decisions to improve patient outcomes.

The intestine (and the gut microbiota), often referred to as the "real brain" of the body, has been implicated in a wide range of diseases, including obesity, and diet has a direct impact on intestinal health. While bloating, flatulence and constipation seem like routine, everyday symptoms, one cannot deny the significant societal burden they impart partly through their effect on the quality of life and partly through the medical and surgical costs they incur on patients desperate to improve symptoms. This book discusses irritable bowel syndrome, which is accompanied by complaints of bloating, flatulence, constipation and diarrhea, from which many people routinely suffer. Furthermore, it presents treatment methods, e.g., dietary and nutritional approaches, and recommendations to change lifestyle and manage digestive symptoms.

Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more.

This reference supplies a comprehensive and current overview of every aspect of gastrointestinal microbiota. Expertly written chapters cover conventional and molecular techniques for the study of differing microbial populations, as well as the analysis of microbial activity and interaction with host bodies. Illustrative and up-to-date, this source showcases how fluctuations in our diet, environment, and pharmaceutical intake affect microbial composition and behavior.

With collaboration of Dr. Alan Buchman, Consulting Editor, Dr. Perry J. Pickhardt has created a comprehensive issue of Gastroenterology Clinics that looks at imaging techniques for gastrointestinal diseases. Experts in their respective fields have contributed clinical reviews in the following areas: Evaluation of Dysphagia: The Role of Barium Fluoroscopy; CT and MR Small Bowel Enterography: Current Status and Future Trends; Radiologic Assessment of Gastrointestinal Bleeding; CT Colonography: Implementation for Screening; Rectal MR for Cancer Staging and Surveillance; Defecography (fluoro vs MR); Noninvasive Imaging Techniques for Staging Liver Fibrosis; HCC Screening: Comparison of US, CT, and MR Approaches; Pancreatic Cystic Lesions; Overview of biliary imaging; Splenomegaly: Clinico-Radiologic Approach to the Differential Diagnosis; MR for Non-Traumatic Acute Abdominal Pain: Comparison with CT and US; and PET/MR: Current Clinical Status and Future Prospects. Gastroenterologists will come away with the knowledge they need to understand the latest imaging modalities for diagnosis and assessment of gastrointestinal diseases and disorders.

Clinical and Translational Perspectives on Wilson Disease brings together the genetics, cell and structural biology of Wilson Disease into one contemporary, easy to navigate handbook. Created to meet the diverse needs of the clinical and research communities surrounding Wilson Disease, this reference provides a worldwide approach that is concise and translational. Specifically, it provides a basis for clinicians to appreciate 'basic science' aspects of Wilson disease, presenting a guide for researchers to understand the clinical disorder on which their research is focused and fostering constructive dialogue and progress for this puzzling disorder.

This book is the proceedings of the Falk Symposium No. 122 on "Inflammatory Bowel Disease - A Clinical Case Approach to Pathophysiology, Diagnosis, and Treatment," held in Bologna, Italy, on June 22-23, 2001, and deals with some major issues concerning Genetics of IBD, Pediatrics in IBD, Early vs Late IBD, Bacteria and Gut Inflammation, Refractory CD, Fistulizing CD, Refractory Distal Colitis, and Complications of Ileal-Pouch Anastomosis. The main aim of the meeting was to highlight the value of an integrated clinical approach and the importance of clinical research in developing innovative methods of treatment.

Helicobacter pylori Protocols offers an outstanding collection of state-of-the-art protocols for the identification and molecular manipulation of H. pylori. The authoritative contributors supply detailed and readily reproducible protocols for the culturing of H. pylori, for the isolation and restriction endonuclease digestion of H. pylori chromosomal DNA, and for the transformation and insertional mutagenesis of H. pylori. They also provide molecular epidemiological techniques, including ribotyping, PCR-RFLP, and RAPD-PCR. These procedures have been developed by leading practitioners to solve the difficult technical problems created by the application of the powerful bacterial genetic and molecular cloning techniques to H. pylori.

Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field.

This book brings together world experts in the field of Functional Gastrointestinal Disorders (FGIDs) who practice an integrated and holistic approach in their care for patients to provide an up-to-date and comprehensive evaluation of a range of issues associated with the biopsychosocial treatment of FGIDs. Examining topics such as neurological and biological aspects of FGIDs, common concerns faced in relation to diagnosis, and ongoing medical decisions and interventions, each chapter provides crucial practical recommendations, as well as future directions of psychosocial work in multi-team environments. Functional Gastrointestinal Disorders considers individual conditions in detail, including the current Rome IV diagnostic criteria for FGIDs required to make a positive diagnosis, the role of psychological and other biopsychosocial and biofeedback aspects of treatment, and general recommendations with regard to diet and medications. Each chapter also provides an up-to-date consolidation and evaluation of the current literature as well as practical recommendations, which can then be applied by the reader in their own interaction with FGID patients. Topics covered include: the common concerns and issues faced by individuals with FGIDs in relation to pre-and post-diagnosis, ongoing medical decisions and interventions review of current evidence-based biopsychosocial treatment practices for each FGID condition the differences and challenges associated with FGIDs across individual life stages special topics such as the relationship with eating disorders and the role of psychotropic medications modern patient centred initiatives such as patient empowerment, distance and e-therapies the future challenges facing FGID treatment. Throughout the entire book, common themes and practical recommendations are described. Functional Gastrointestinal Disorders, has broad applicability across multiple spheres, including treatment, research and teaching and is accessible to those working in gastroenterology and primary care alike.

The field of liver transplantation has undergone tremendous change and continues to evolve at a fast pace. This book covers topics beyond standard care and discusses issues that are new and rapidly evolving in the field. These include innovative surgical methods to maximize the donor pool, non-surgical methods to expand the existing pool of additional donors, the changing face of liver rejection, and management of infections in the presence of new antivirals.This book is an interesting read for surgeons, hepatologists, and healthcare workers looking after patients who need or have had a liver transplant.

Brain Tryptophan Perturbation in Hepatic Encephalopathy: Implications for Effects by Neuropsychoactive Drugs in Clinical Practice; F. Bengtsson, et al. Hepatic Encephalopathy in Acute Liver Failure: Role of the Glutamate System; A. Michalak, et al. Glutamate and Muscarinic Receptors in the Molecular Mechanisms of Acute Ammonia Toxicity and of Its Prevention; M.D. Minana, et al. Studies on the Pharmacological Properties of Oxindole (2-Hydroxyindole) and 5-Hydroxyindole: Are They Involved in Hepatic Encephalopathy?; F. Moroni, et al. The Involvement of Ammonia with the Mechanisms That Enhance GABA-ergic Neurotransmission in Hepatic Failure; E.A. Jones, A.S. Basile. Direct Enhancement of GABA-ergic Neurotransmission by Ammonia; J.-H. Ha, et al. The Peripheral Benzodiazepine Receptor and Neurosteroids in Hepatic Encephalopathy; M.D. Norenberg, et al. Ornithine Aminotransferase as a Therapeutic Target in Hyperammonemias; N. Seiler. Sparse-Fur (spf) Mouse as a Model of Hyperammonemia: Alterations in the Neurotransmitter Systems; I.A. Qureshi, K.V.R. Rao. Abnormal Gene Expression Causing Hyperammonemia in Carnitine-Deficient Juvenile Visceral Steatosis (JVS) Mice; T. Saheki, et al. 7 Additional Articles. Index.

This book, the proceedings of Falk Symposium 163 Chronic Inflammation of Liver and Gut, held in Hangzhou, P.R. China, on March 14--15, 2008, presents the most recent progress in chronic inflammatory diseases of liver and gut. It focusses on molecular understanding, the therapeutic state of the art and future options of treatment.

The first part of the book concentrates on basic and clinical aspects of IBD. Chapters demonstrate the role of the immune system, genetic factors and the intestinal microflora in IBD, and give an evidence-based update on the current diagnostic and therapeutic options and present future perspectives for the management of IBD. The second part is devoted to chronic liver diseases with particular focus on the liver as an immune organ, treatment strategies of viral hepatitis and liver fibrogenesis. The final part deals with basic and clinical aspects of liver cirrhosis, hepatocellular carcinoma and liver transplantation. The book concludes with an outlook on therapeutic options of hepatic stem cells. Throughout, international experts from the USA, the People s Republic of China and Europe contribute their experience in different aspects of the mechanisms and management of chronic inflammatory diseases of liver and gut. "

This project will cover the diagnosis and treatment of esophageal diseases in a concise and easy-to-read format. Pathophysiology, diagnostic evaluation, treatment and strategies for avoiding and managing complications are included and based both on evidence-based data and the experience of the Editors and the roster of international contributors. Each chapter will describe the current diagnostic and management strategies of the disease process and simplified operative approaches with relevant technical considerations will be outlined in an easily understandable manner for the specific target audience. The text will be illustrated throughout by easy to understand illustration line graphs that depict fundamental anatomic or technical principles.

Krankheiten der Leber.- Akute und chronische Virushepatitiden.- Bakterielle und parasitare Leberkrankheiten.- Leberkrankheiten bei Aids.- Autoimmunhepatitiden und Overlap syndrome.- Primar-biliare Zirrhose, primar-sklerosierende Cholangitis und "Vanishing-bile-duct"-Syndrom.- Hamochromatose (hereditare Hamochromatose; sekundare Eisenuberladungssyndrome).- Morbus Wilson.- ?1-Antitrypsinmangel.- Zystische Fibroese.- Primare Stoffwechsel- und Speicherkrankheiten.- Porphyrien.- Hyperbilirubinsyndrome.- Medikamentoese/toxische Leberschaden und alkoholische Leberkrankheiten.- Nichtalkoholische Steatohepatitis (NASH).- A Vaskulare Lebererkrankungen.- B Graft-versus-Host-Krankheit der Leber.- Pulmonale Komplikationen bei Leberkrankheiten.- Leber- und Systemerkrankungen.- Leber: Wechselwirkungen mit dem hamatopoetischen System.- Hep atop athien in der Schwangerschaft.- Krankheiten der Gallenblase und Gallengange.- Cholezystolithiasis und Choledocholithiasis.- Cholezystitis.- Cholangitis.- Anomalien der Gallenwege und Strikturen.- Sphinkter-Oddi-Dysfunktion.- Aids-assoziierte Cholangitis.- Leberzirrhose und Komplikationen.- Leberzirrhose.- Leberzirrhose und portale Hypertension.- Leberzirrhose und Aszites.- Hepatische Enzephalopathie.- Leberzirrhose und spontan-bakterielle Peritonitis.- Leberzirrhose und Nierenfunktionsstoerungen.- Leberzirrhose und Gerinnungsstoerungen.- Tumoren der Leber, Gallenblase und Gallenwege.- Benigne Tumoren der Leber, Gallenblase und Gallenwege.- Maligne Tumoren der Leber und Gallenwege.- Lebermetastasen.- Leberveranderungen bei hamatologischen Neoplasien.- Akutes Leberversagen und Transplantation.- Akutes fulminantes Leberversagen.- Indikationen zur Lebertransplantation.- Vorbereitung zur Lebertransplantation.- Intra- und postoperatives Management bei Lebertransplantation.- Nachsorge bei Lebertransplantation.- Pharmakotherapie und Ernahrung.- Pharmakotherapie bei vorgeschadigter Leber.- Leber und Ernahrung.- Sozialmedizinische Beurteilung bei Leber und Gallekrankheiten.- Sozialmedizinische Aspekte.

Since the previous M.D. Anderson Solid Tumor Oncology Series publication on pancreatic cancer, there have been major advances in our understanding of molecular events which underlie pancreatic cancer development, both in the sporadic and inherited forms. This book provides information on the recent progress and improvements. It brings to the forefront the most current advances that have been made in understanding pancreatic cancer development and successfully treating this disease.

This book provides a comprehensive overview of the full spectrum of benign oesophageal disorders with an emphasis on surgical approaches. There are now new, sophisticated diagnostic methods and endoscopic treatment modalities which represent the high level of innovation within the field. These innovations are assimilated here through evidence-based chapters, written by practitioners and experts in their specific subjects. Some of the topics include gastroesophageal reflux disease, Barrett's oesophagus, oesophageal motility disorders, oesophageal diverticula, oesophageal caustic injuries, and discussion of minimally invasive surgery.This comprehensive, practical overview is suitable not only for medical students or residents interested in gastroenterology and gastroenterological surgery, but also for clinicians and practitioners.

This volume provides a comprehensive overview of quality metrics and methods used to improve quality for all major modalities of CRC screening. It introduces the readers to the evidence of effectiveness behind various CRC screening modalities: stool-based tests (Fecal Occult Blood, Fecal Immunochemical and Fecal DNA tests), flexible sigmoidoscopy, colonoscopy and CT colonography. In-depth chapters review the latest guidelines for CRC screening, compare differences among the five major national guidelines, and highlight the need for valid quality and cost indicators. While the main focus of this volume is on colonoscopy, since most quality indicators and analyses have focused on this modality of screening and surveillance, one chapter is devoted to quality indicators of other screening modalities. Differences between process and outcome measures are also highlighted and a small but valid set of recommended national measures are listed. Written by experts in the field, Colorectal Cancer Screening: Quality and Benchmarks is an important and useful resource written for gastroenterologists, primary care physicians, general and colorectal surgeons, family physicians, and investigators with research focus in screening and quality metrics.

This issue of Surgical Clinics of North America focuses on Advances in Colorectal Neoplasia, and is edited by Dr. Sean J. Langenfeld. Articles will include: Colorectal cancer screening; Imaging for colon and rectal cancer; The difficult colorectal polyp; Emergency presentations of colorectal cancer; Advances in laparoscopic colorectal surgery; Robotic colorectal surgery; Local excision of rectal cancer; New strategies in rectal cancer; Hereditary colorectal cancer syndromes; Dysplasia and cancer in inflammatory bowel disease; Atypical colorectal neoplasms; Resection of the primary tumor in stage IV colorectal cancer: when is it necessary?; Cytoreduction and HIPEC for colorectal cancer; Molecular markers for colorectal cancer, and more!