About this book— In recent years, a number of different spectroscopic techniques have been applied to the study of a wide range of biomedical topics. Biomedical investigations in fields as diverse as eye lens research, the study of cardiovascular and inflammatory diseases, and the study of oxidative stress in disease can now be carried out by spectroscopic means. The nine chapters in Biomedical Applications of Spectroscopy present an authoritative overview of the current status of the field, with each chapter written by acknowledged experts. A wide range of techniques is considered, including optical microspectroscopy, Raman spectroscopy, FTIR spectroscopy, NMR and EPR spectroscopy and mass spectrometry. This highly topical volume will stimulate interest in this expanding field, and point the way towards future directions in research. The major objectives of this established series are to integrate theory and practice and to bring together different branches of both academic and industrial research through the presentation of critical review articles in fundamental and applied spectroscopy. The policy of the editors is to commission authoritative reviews by acknowledged leaders in the various fields of spectroscopy. Thus each volume presents a carefully composed picture of the ‘state of the art’ for a particular area. For each volume the subject matter is presented in a manner which is Comprehensible to the non-expert, for whom the series will continue to provide a valuable introduction, and a timely overview of topics in spectroscopy which are of current interest and importance. At the same time the involved expert will find much to engage his or her attention. The series is of interest to research scientists and technologists, to teachers and both graduate and undergraduate students.

Society-sanctioned guidelines are valuable tools, but accessing key information can be a daunting task. This book illuminates a clear path to successful application of the American Heart Association/American Stroke Association guidelines. Organized for fast reference, this new volume helps practitioners improve patient care.

It has never been easy to introduce new concepts and therapeutic in-terventions into surgical practice. When attempting to do so, one is faced with the interagency of traditional dogma, which still in this era of evidence-based medicine tends to dominate the surgical thought pr- ess. This is particularly so in the area of coloproctology, where prejudice and personal opinion often influence objective analysis whenever tradition is challenged. A large body of literature on anorectal prolapse has accumulated over the years; although much is based on personal viewpoint rather than scientific evidence, it has nevertheless been passed down through the generations as ac-cepted wisdom and practice. As a consequence, it is a challenge to change the mindset of a generation of surgeons and to introduce new concepts and novel techniques which at first might appear to be a radical departure from conventional teaching. It is obviously not possible to present the basis for the develop-ment of transanal stapling techniques for anorectal prolapse in this Foreword; this is dealt with in detail elsewhere in this book. The in-terested reader will have the opportunity to share in the new and emerging concepts surrounding anorectal prolapse and to deepen their understanding of the pat- physiology and basis for surgical correction. Although hemorrhoidal disease and external rectal prolapse have been known about for centuries, the understanding of internal rectal prolapse (intussusception) and rectocele has only really advanced with the emergence of radiological imaging tech-niques, such as defecography.

Our increased understanding of health and disease coupled with major technologic advances has resulted in rapid and significant changes in the practice of medicine. How we prepare physicians for clinical practice 20, 30, or 40 years from now is of paramount importance to medical educators, to the future professionals, and to society at large. Implementing Biomedical Innovations into Health, Education, and Practice delves into this important question, discussing the effects of precision medicine, bioinformatics, biologic and environmental forces, and societal shifts on the physician's approach to diagnosis and therapy. The author interviewed world-renowned physicians, medical educators, healthcare leaders, and research professionals-their insights and quotes are woven throughout the narrative. Professionally illustrated, this relevant resource is a must-have for all medical professionals who incorporate technology and biomedical innovations in their research and clinical practice. It encourages thoughtful analysis on adapting and developing the foundational knowledge, skills, and aptitudes of future physicians and other healthcare professionals, and it belongs in your library. "Having completed deanship at one of America's leading medical schools, Jim Woolliscroft produces an insightful, contemplative projection of the likely skill and behavioral needs of the physician workforce for the mid-21st century...The result is a playbook for physician training that responds effectively to the daunting challenges faced in the coming transformation of the role of physicians in protecting the health of our nation." James L. Madara, MD, CEO, American Medical Association "Dr. Woolliscroft's provocative new book will become must reading for all who are serious about educating the next generation of physicians and health care leaders. Leveraging his own experience as a consummate educator and interviews with numerous thought leaders, he identifies the uncertainties, challenges and disruptions to the practice of medicine in the decades ahead. The implications and imperatives for the coming generations of physicians are compelling and of critical importance for care givers, policy makers, and most pointedly educators in the U.S. and around the world." Gary S. Kaplan MD, Chairman and CEO, Virginia Mason Health System "This ambitious masterpiece, by one of the leading medical educators of our time, fully captures the ongoing changes and disruptions in medicine today, and how they will influence the care of patients and the training of young physicians in the future." Eric Topol, MD, Executive Vice President, Scripps Research, Author of Deep Medicine

This work brings together a selection of Clinical Forum features from the journal "Aphasiology". The fora are designed to cover issues in clinical aphasiology which are central, topical and controversial. Each forum concerns a main article and a number of commentaries.

In der Intensivmedizin ist es oft notwendig, rasch erste therapeutische Massnahmen ohne Fehler und Unsicherheiten vorzunehmen. Dieses Buch bietet den Arzten wahrend ihrer intensivmedizinischen Ausbildung eine schnelle und ubersichtliche Hilfe in der kompetenten Betreuung eines breiten Patientenspektrums an einer chirurgischen Intensivstation. Haufige Krankheitsbilder aus Abdominalchirurgie, Thoraxchirurgie, Herzchirurgie, Traumatologie, Geburtshilfe und Innerer Medizin werden behandelt und die pathophysiologischen Vorstellungen erlautert. Daruber hinaus werden grundlegende Kenntnisse in Bezug auf kunstliche Beatmung sowie alternative Techniken vermittelt und die Thematik der parenteralen und enteralen Ernahrung ubersichtlich und praxisnah dargelegt. Krankheitsbildern wie Sepsis mit ihrer Pathophysiologie und damit verbundener Verzahnung von Gerinnung und Inflammation wurde besonderes Augenmerk gewidmet, so dass neue und teils noch in Entwicklung befindliche Therapieansatze beurteilt werden konnen."

Integrated Medical Sciences: The Essentials is a concise, accessible, problem-based approach to the subject using case scenarios to facilitate students taking their pre-clinical or basic sciences examinations.Using a family of characters in each case scenario, the aim of the text is to reflect the current changes in medical and biomedical science curriculum that is increasingly moving towards a more integrated approach through problem-based learning. The characters, all members of an extended family, will appear in several scenarios and the student will become familiar with their personalities and their disease processes. Each case study will therefore cover the relevant anatomy, physiology, pathology, pharmacology, microbiology, immunology and biochemistry and enable the reader to grasp the key concepts of basic medical sciences in an integrated fashion.

Takes an integrated approach to the subject to reflect recent changes in medical and biomedical science curriculum Further Study sections to enhance understanding and enable the student to read around the subject Intended learning outcomes included at the beginning of each chapter Trigger Boxes containing key facts and revision questions included throughout to ensure key concepts are fully understood

An essential text for first and second year undergraduates taking medical or biomedical sciences (during the pre-clinical phase for medical students.). The book will also be invaluable to nursing degree students and allied health students taking courses in dentistry, physiotherapy and pharmacy. In addition, the book will be ideal for US and International medical students preparing for the USMLE Step 1 examination.

Despite what you might have been told, we're not inherently selfish. The truth is we're inherently kind.Scientific evidence has proven that kindness changes the brain, impacts the heart and immune system, is an antidote to depression and even slows the ageing process. We're actually genetically wired to be kind. In The Five Side Effects of Kindness, David Hamilton shows that the effects of kindness are felt daily throughout our nervous system. When we're kind we feel happier and our bodies are healthiest.In his down-to-earth and accessible style, David shares how: *Kindness makes us happier *Kindness is good for the heart *Kindness slows ageing *Kindness improves relationships *Kindness is contagious

This comprehensive book thoroughly addresses all aspects of health care transition of adolescents and young adults with chronic illness or disability; and includes the framework, tools and case-based examples needed to develop and evaluate a Health Care Transition (HCT) planning program that can be implemented regardless of a patient's disease or disability. Health Care Transition: Building a Program for Adolescents and Young Adults with Chronic Illness and Disability is a uniquely inclusive resource, incorporating youth/young adult, caregiver, and pediatric and adult provider voices and perspectives. Part I of the book opens by defining Health Care Transition, describing the urgent need for comprehensive transition planning, barriers to HCT and then offering a framework for developing and evaluating health care transition programs. Part II focuses on the anatomic and neuro-chemical changes that occur in the brain during adolescence and young adulthood, and how they affect function and behavior. Part III covers the perspectives of important participants in the HCT transition process - youth and young adults, caregivers, and both pediatric and adult providers. Each chapter in Part IV addresses a unique aspect of developing HCT programs. Part V explores various examples of successful transition from the perspective of five key participants in the transition process - patients, caregivers, pediatric providers, adult providers and third party payers. Related financial matters are covered in part VI, while Part VII explores special issues such as HCT and the medical home, international perspectives, and potential legal issues. Models of HCT programs are presented in Part VIII, utilizing an example case study. Representing perspectives from over 75 authors and more than 100 medical centers in North America and Europe, Health Care Transition: Building a Program for Adolescents and Young Adults with Chronic Illness and Disability is an ideal resource for any clinician, policy maker, caregiver, or hospitalist working with youth in transition.

The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.

Die akute Appendizitis gilt in der heutigen Zeit als die haufigste operationsbedurftige Erkrankung des Bauchraums und als die Hauptursache des akuten Abdomen. Seit Anfang des 20. Jh.s ist die Appendektomie als Therapiemassnahme bei akuter Appendizitis eine der am meisten durchgefuhrten chirurgischen Eingriffe, sodass sie mittlerweile zur Routine gezahlt wird. Jedoch weit weniger bekannt ist die Tatsache, dass die Existenz des Wurmfortsatzes erst am Ende des 15. Jh.s durch Leonardo da Vinci erkannt wurde und das Krankheitsbild einer entzundeten Appendix vermiformis erst viel spater im 19. Jh. unter den Medizinern etabliert war. Vor diesem Hintergrund untersucht die Autorin, wie sich der Weg hin bis zur Entdeckung der Appendix vermiformis und die Etablierung des Krankheitsbildes und dessen Therapie im klinischen Alltag gestaltete und welche Grunde diesen Weg zu einem langwierigen machten.

I wrote this book urged by the overwhelming desire that arises towards the end of life to recapitulate the past. My goal was to summarize my experience of practicing science at the end of the 20th and early 21st centuries in Argentina, a country located far away from the world's leading scientific centers. In the book, I summarize the intricacies of the pineal gland ("the stone of madness") as historical, mystical and medical entity and its entry in contemporary medicine with the description of melatonin. I also reflect on how being associated with an unexplored subject at the beginning of his scientific career impacts the life of a scientist throughout their entire life. Today we know that in humans pineal melatonin is released every day late in the evening, and there is evidence that it is the trigger for the sleep process. But the most exciting aspect of melatonin is that it is a substance that is present in all living creatures, from unicellular organisms to plants and higher mammals, a fact that evinces its importance for life. Further, the neuroprotective action of melatonin promises to be crucial for the control of neurodegenerative diseases we face as a pandemic in this century. The discoverer of melatonin, Aaron Lerner, based its name on melano, the Greek word for black, because of its effect on the pigment cells of the skin. As in "La vie en rose", the immortal Edith Piaf song written in 1946, my lifelong work with melatonin could well be called "Ma vie en noir".

Advances in Clinical Chemistry, Volume 88, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

This issue of Medical Clinics, Guest Edited by Dr. Kerry B. Dunbar, is devoted to Gastroenterology. Articles in this issue include: Proton Pump Inhibitors: What the Internist Needs to Know; Management of Refractory GERD; Colonoscopy, Polypectomy, and the Risk of Bleeding; Pancreatic Cysts: Sinister Findings or 'Incidentalomas'?; The Future of Non-Alcoholic Fatty Liver Disease Treatment; Effective Treatments for Irritable Bowel Syndrome; The Revolution in Treatment of Hepatitis C; Diet and the Role of Food in GI Symptoms; Eosinophilic Esophagitis; Colorectal Cancer Screening: Is Colonoscopy the Best Option?; Celiac Disease and Gluten Sensitivity; Management of Chronic Pancreatitis; and Helping Patients with Gastroparesis.