Why can two people use a drug and one person becomes addicted while the other does not? Determinants of Addiction: Neurobiological, Behavioral, Cognitive, and Sociocultural Factors unravels the complexities underlying addiction to understand how individual factors at the genetic, cellular, anatomical, cognitive-behavioral, and sociocultural level can influence susceptibility to substance use disorders. The first section reviews the neurobiological determinants of addiction and examines how drugs hijack the reward pathway and alter numerous neurotransmitter systems such as dopamine. The second section covers the behavioral-cognitive determinants of addiction such a conditioning, memory processes, and decision-making. The final section examines individual differences in addiction vulnerability, with a focus on personality factors, sociocultural factors, sex/gender, and stress. The book references commonly used drugs such as nicotine, ethanol (alcohol), opioids, and cocaine.

Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment.

This atlas, compiled by experienced specialists in the field, is designed as a ready reference on the use of parathyroid scintigraphy in patients with hyperparathyroidism, both for the localisation of parathyroid pathology and as an aid to surgery. The introductory chapters review the basic core knowledge on the subject. Eighty case reviews are then presented, covering gamma camera planar imaging, SPECT, hybrid SPECT-CT, and also PET-CT. In total, 240 illustrations are included, comprising 160 grey-scale photos depicting nuclear medicine and CT images and 80 dual-modality fusion colour photos. This compilation of illustrative clinical cases will greatly assist clinicians and imaging specialists in image interpretation in different settings. The images replicate normal conventional formats used for routine reporting and hence facilitate fast and reliable diagnosis. Each of the case reviews includes documentation of the procedure, findings, and conclusions with relevant commentary. Surgeons, nuclear medicine physicians, and radiologists will find the Radionuclide Parathyroid Imaging: Book and Atlas to be a valuable practical tool and learning aid.

Developed by a renowned group of international authors, this engaging, case-based title once again offers readers a wide range of thought-provoking case studies that reflect contemporary, challenging, hands-on clinical care. Expanded and fully updated, Endocrinology and Diabetes: A Problem Oriented Approach, 2nd Edition addresses the complete range of endocrinologic problems found in patient care, offering the reader a convenient and pointed way to solve clinical problems in a timely manner. Due to its comprehensive coverage and practical focus, this title has developed a special place in the field of endocrinology and will again be of great interest to endocrinologists, diabetologists, internal medicine physicians, family physicians, fellows, and residents. The enthusiastic reception and warm welcome of the first edition of this book was overwhelming and gratifying. Despite many standard texts that cover physiology and clinical aspects of endocrinology, this book found a special place because it focused on patient care and practical aspects of endocrine practice. In the current volume we were fortunate to again have the honor of collaboration by international authors who pride themselves foremost as clinical endocrinologists. We hope our readers will find this updated, improved edition worthwhile, and use it for the benefit of their patients.

This book is a comprehensive guide to the assessment and management of adults with thyroid disorders in daily clinical practice. All important aspects and disorders are considered. Relevant information on basic anatomy, embryology, immunology, and physiology is included to provide a better basis for understanding the development of disease and its diagnosis and treatment. Currently available biochemical tests and other specific diagnostic tools are also considered in detail. The various common thyroid disorders are then discussed in a series of individual chapters that focus on etiology, pathophysiology, symptomatology, diagnosis, and treatment. Numerous high-quality illustrations and concise fact boxes are included. The authors are all experts with wide experience in three disciplines and a long-standing interest in thyroid disease.

This innovative textbook provides a readable, contemporary and fully integrated introduction to endocrine glands, their hormones and how their function relates to homeostasis. It explores the pathology of endocrine disease by relating the underpinning science through a wealth of clinical scenarios and examples. The book integrates basic and clinical aspects for a range of endocrine glands and their hormones and includes a number of specialist chapters that also address areas of intense research and clinical interest including the regulation of salt, appetite and endocrine-immune interactions.

Provides a fully-integrated, scientific and clinical introduction to endocrinology. Includes a wealth of colour illustrations to reinforce key concepts.Introduces clinical scenarios and leading questions to engage interest and illustrate the relevance of the underpinning science.Includes key references and suggestions for further reading at the end of each chapter.

Written by a highly respected and experienced author team this new textbook will prove invaluable to students needing an original, integrated introduction to the subject across a variety of disciplines including biomedical science, pharmacology, bioengineering and pre-clinical medicine.

Bone Marrow Diagnosis, Third Edition, is an essential resource for pathologists and haematologists who need to report bone marrow trephine biopsies. Practical and highly illustrated this edition has been comprehensively updated whilst remaining succinct and concentrating on the core information necessary to make an accurate diagnosis. The text provides comparisons of the common methods of sample collection, fixation and staining, and a clear description of how to examine a trephine section. Applying a consistent approach, the chapters cover the range of disorders of bone marrow, discussing the clinical features, histopathology of bone marrow and diagnostic problems of each condition. Each chapter closes with a summary of key points and each diagnostic entity is accompanied by high quality images, over 900 in all, showing typical and more unusual examples of histological features. This compact text, oriented at diagnosis and comprehensively accompanied by usable illustrations, is an invaluable reference tool for the trainee and practicing histopathologists, pathologists and haematologists. * A practical guide aimed at allowing a busy pathologist to easily find the essential description and illustration of the most common bone marrow diseases seen in trephines * Covers new treatment for chronic myeloid leukaemia, B-cell lymphoma and antibody treatments * High quality colour images accompany each diagnostic entity * Coverage of cytology in sections relating to myeloid dysplasias and acute leukaemias * Addresses lymphoma categorization and individual lymphoma entities * Incorporates new WHO classifications of lymphomas and leukaemias

The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe. This volume summarizes research on the anatomy and function of the temporal lobe under both normal and pathological conditions. In addition, it discusses the interactions of the temporal lobe with other brain structures. The book highlights the role of the temporal lobe in language processing as well as vision, object, face recognition and processing. The book also discusses the temporal lobe's role in reading, speech and the processing of color, music, action and memory. Temporal lobe disorders, assessments and treatments are also covered, including encephalitis, Alzheimer's, epilepsy, Korsakov's syndrome, and more.

Auf die Bedurfnisse der taglichen Praxis abgestimmt
Strukturierte, klar definierte Vorgehensweisen fur Diagnostik, Therapiekonzepte und personalisierte Therapieziele.

Umfassende Information, inklusive
- Pravention, Fruherkennung
- Begleiterkrankungen: Fettstoffwechselstorungen, Hypertonie ...
- Folgeerkrankungen: Gefasserkrankungen, Nephropathie, Neuropathien ...
- Patientenschulung: Ernahrung, Lebensfuhrung ...
Besonderheiten bei
- Kindern/Jugendlichen, Schwangeren, alten Patienten
- perioperativer Betreuung, enteraler und parenteraler Ernahrung
- psychiatrischen Erkrankungen einschliesslich Demenz
- Sport, Reisen
Komplexe Fragen kompetente Antworten
- Stufentherapie individuell abgestimmt auf Begleiterkrankungen, Bedurfnisse und Moglichkeiten des Patienten
- Praxistipps fur typische und atypische Therapieprobleme
- neue und zukunftige Therapieformen

NEU u.a.
- Bariatrische Chirurgie
- Compliance und Empowerment
- Qualitatssicherung und Versorgungsforschung
- DMPs, DRGs

Nach den Leitlinien/Richtlinien
- Deutsche Diabetes Gesellschaft (DDG)
- Osterreichische Diabetesgesellschaft (ODG)
- Schweizerische Gesellschaft fur Endokrinologie und Diabetologie (SGED)

Interdisziplinar, topaktuell. Von den fuhrenden Experten aus Deutschland, Osterreich, Schweiz.

Wissen fur das optimale Diabetes-Management gerade heute besonders wichtig."

Effectively manage parathyroid and bone metabolism disorders with The Parathyroid Gland and Bone Metabolism! Brought to you by the same leading endocrinologists responsible for the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric, this derivative book presents a compilation of chapters covering all endocrinology material related to parathyroid and bone metabolism. Never before available as a stand-alone offering, this content will enable you to give your patients the benefit of today's best know-how on parathyroid and bone metabolism from the leading resource in endocrinology. Stay abreast of the newest knowledge and advances on parathyroid and bone metabolism, including. pediatric parathyroid disorders and bone metabolism disorders major diseases common to the aging population such as osteoporosis advances in the genetics of disorders involving calciotropic hormones newer diagnostic approaches and therapies for bone diseases, from osteoporosis to Paget's disease and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion.

Apply the latest advances in management of neuroendocrine and pituitary disorders with the Neuroendocrinology & The Pituitary Gland! Brought to you by the same expert endocrinologists responsible for the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric, this derivative book presents a compilation of chapters covering all material related to neuroendocrinology and the pituitary gland. Never before available as a stand-alone offering, this content will enable you to give your patients the benefit of today's best neuroendocrine and pituitary know-how from the leading resource in endocrinology. Stay abreast of the newest knowledge in neuroendocrinology and the pituitary gland, including. the most recent understanding of fundamental cellular and physiologic functions of the neuroendocrine system mechanisms underlying clinical disorders approaches to managing patients harboring disorders of the hypothalamus and pituitary gland and much more. Approach any subject either by specific gland or through a discussion of multi-hormonal integration of endocrine function, as led by the "master conductor of the endocrine orchestra," the pituitary gland. Gain a state-of-the-art understanding of comprehensive descriptors, integrating endocrine cell ontogeny, hormonal control of growth and maturation processes, and childhood and young adult pathophysiology with maturation and aging processes. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical endocrinology decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion.

Effectively manage reproductive endocrinology issues with Reproductive Endocrinology, a new book derived from the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric. Never before available as a stand-alone offering, this compilation of chapters will enable you to give your patients the benefit of today's best know-how from the leading resource in endocrinology. Stay abreast of the newest knowledge in reproductive endocrinology, including. endocrinology of sexual behavior and gender identity genetic pathways that control gonadal development and sex differentiation management of PCOS and hirsutism, male androgen deficiency, and gynecomastia and much more. Effectively review the causes and management of precocious or delayed puberty. Count on all the authority that has made Endocrinology, 6th Edition, edited by leading endocrinologists Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical decisions in reproductive endocrinology with an enhanced emphasis on evidence-based practice in conjunction with expert opinion.

Give your patients the benefit of today's best adrenal endocrinology know-how with The Adrenal Gland, a new derivative book from the same expert endocrinologists responsible for the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric. Never before available as a stand-alone offering, this compilation of chapters from the leading resource in endocrinology covers all material related to the adrenal gland. Stay abreast of the newest knowledge and advances in adrenal endocrinology, including. the molecular genetics of pheochromocytomas and paragangliomas the newest therapies for adrenocortical carcinoma, written by the organizers of the first major international trials a survey of adrenal imaging, authored by the world's major diagnostic imaging specialist on cross-sectional CT and MR scanning of the adrenal gland a comprehensive survey of adrenarche and the adrenopause - topics not adequately covered in most other adrenal endocrinology books and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical endocrinology decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion.

This book provides a complete review of multiple metabolic disorders and the use of phytochemicals for their prevention and treatment. When describing each metabolic disorder, all authors describe de main health alterations, providing the most current figures and statistics worldwide; medicinal plants used in traditional medicine for its treatment and scientific information related to their potential to prevent or treat each condition. Authors also include a complete scientific background check, complete analysis of all phytochemicals recommended for each disorder, a description of the mechanism(s) of action and in vivo and/or in vitro studies. Within this volume, a series of 3 plant species, recommended to treat or prevent the previously described disorders, are presented with their botanical information, traditional use in different cultures and countries, and the available scientific information validating their health benefits. Besides six main metabolic disorders are described, providing a full scientific background for its general understanding, and three study cases are presented, where metabolic disorders are analyzed and approached from different medical and pharmaceutical angles.

Schwangerschaft bei Diabetes? Dank neuer Therapien konnen sich Diabetikerinnen heutzutage ihren Kinderwunsch erfullen. Voraussetzung ist allerdings die kompetente, luckenlose Begleitung der Schwangerschaft. Experten bieten hierfur alle notwendigen Informationen (inkl. Gestationsdiabetes) - praxisbezogen, ubersichtlich und verstandlich. Exakt erlautern sie welche Massnahmen, wann und wie einzusetzen sind. Alles rund um die Pravention sowie Begleit- und Folgeerkrankungen: wichtige Parameter und deren Uberwachung, Diagnose, Therapie, medikamentose Intervention. Ein hilfreicher Ratgeber fur werdende Mutter sowie alle Fachleute, die sie betreuen."

If you or a loved one has been diagnosed with a thyroid condition, you've probably found out at least a little about this mysterious gland-just enough to want to look for answers to the many questions that keep popping up in your mind. What causes this condition? How is it treated? What can you do to get healthy again? Thyroid for Dummies, 2nd Edition gives you the detailed information you're looking for on new methods for detecting thyroid disease in both adults and children, alternative treatments, pros and cons of powerful new drugs now on the market, advice for managing the disease through changes in exercise and diet, and much more. You're discover: * What the thyroid does * How to identify a sick thyroid and recognize who's at risk * Ways to find the right thyroid doctor * How to cope with hypothyroidism in children * The hereditary connection to thyroid disease * How thyroid disease affects the elderly * The effects of hyperthyroidism during pregnancy * How to decide if surgery is necessary * Ten myths about thyroid health Updated to address advances made since the first edition, including the latest thinking on understanding thyroid disease's connection to depression and mania, Thyroid for Dummies, 2nd Edition will tell you everything you need to know about how the thyroid functions, what makes it malfunction, and what to do when a problem occurs.

Recognising a need to promote and enhance teaching of clinical endocrinology and diabetes in UK medical schools, the Society for Endocrinology, in collaboration with Diabetes UK and the Association of British Clinical Diabetologists, created a national curriculum that sets out the minimum recommended standards for undergraduate medical education. Clinical Endocrinology and Diabetes at a Glance corresponds to the curriculum and covers all important areas of diabetes and endocrinology in a clinically relevant and concise manner, with complementary figures to ensure principles are explained clearly. It highlights key practical skills for undergraduates in line with the GMC recommendations that medical graduates should be well prepared for their Foundation posts. There is also emphasis on the importance of multidisciplinary teams in the management of endocrine diseases and diabetes. These include sections on structured education programmes, psychosocial aspects, and patient self-management and monitoring. Clinical Endocrinology and Diabetes at a Glance will serve as a valuable resource for medical students and junior doctors treating patients with these conditions.

Air pollution has been associated with significant adverse health effects, including increased morbidity and mortality. The global increase in the prevalence of diseases that are associated with exposure to air pollution is of great concern. In particular, severe PM2.5 pollution occurs in Asian countries due to increasing emissions of air pollutants caused by the countries' rapid economic growth. A number of studies have been performed to clarify the association between PM2.5 and disorders such as asthma, ischemic cardiovascular diseases, arteriosclerosis, cancer, and neurological disorders. It is important to protect populations that are susceptible to such pollution. While the characterisation and monitoring of pollutant components currently dictates pollution control policies, it will be necessary to identify susceptible populations in order to adequately target prevention strategies for the health effects of air pollution. This book offers a comprehensive review of the recent advances in our understanding of the health effects of PM2.5, the role of oxidative stress in these effects, the contribution of ultrafine fractions of PM2.5 to the health effects, and discusses prevention strategies for these health effects. It also suggests further risk assessment, risk management, and novel policies for PM2.5 pollution, required to protect public health.

The present book provides a state-of-the-art overview of the adrenal gland pathophysiology. It covers both up-to-date basic and clinical notions on adrenal glands. Amidst the molecular aspects, discussed by leading scientists in the field, there are ER stress, microRNA, hormone biosynthesis, and interactions with other organs. Clinical insights for students and physicians are also provided, from the imaging to the therapeutic management of common disorders of the gland, including adrenal failure, hyperaldosteronism, Cushing's syndrome, neurologic disease, and cancer both in adults and pediatric patients. As mentioned above, chapter contributions are made by worldwide renowned experts, scientists and physicians, working in prestigious hospitals and universities including Brown, Oxford, Case Western Reserve University, Cleveland Clinic, Chinese University of Honk Kong, University of Tennessee, Indiana University School of Medicine, Monash Health in Clayton, Australia, University of Calgary, Northern Ontario School of Medicine and Laurentian University, Medical University of Gdansk, Universite Pierre et Marie Curie in Paris, France, University of Minho, Braga, Portugal, St. Vincent's University Hospital in Dublin, Universities of Londrina, Alfenas, Sao Paulo, and Rio de Janeiro, Brazil. Throughout these chapters, the authors spotlight future avenues for research in basic pathophysiology and in therapy/prevention, in addition to thorough overviews of the current literature pertaining to the adrenal gland and its functional roles. The book also includes several color photographs, schemes and diagrams of molecular relationships, and tables that support and complement the text. The comprehensive and systematic overview provided within this book is expected to assist the reader in comprehending the importance of taking into account the functional roles of the adrenal gland and also to address questions and unresolved issues regarding the treatment of its disorders. Finally, the editor would like to express his sincere appreciation to all the contributors for their dedicated collaboration in this project. He would also like to thank Ms. Carra Feagaiga for her patient support. He sincerely hopes this book will enable readers to connect basic research principles with up-to-date clinical knowledge, thereby encouraging future discoveries and developments of new therapeutic strategies to treat disorders of the adrenal gland.

Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.